Click here to switch to the map view.

The map label for this gene is atpA [H]

Identifier: 238917849

GI number: 238917849

Start: 2001100

End: 2002608

Strand: Reverse

Name: atpA [H]

Synonym: EUBELI_01930

Alternate gene names: 238917849

Gene position: 2002608-2001100 (Counterclockwise)

Preceding gene: 238917850

Following gene: 238917848

Centisome position: 93.4

GC content: 41.35

Gene sequence:

>1509_bases
ATGAATTTAAGACCGGAAGAAATCAGTTCAGTTATAAAAGAACAGATAAAGAGATATTCTACCGAACTTGAAGTATCAGA
TGTTGGTACTGTTATTCAGGTAGCAGATGGTATCGCACGAATTCATGGATTAGAAAAGGCCATGCAGGGAGAACTTCTTG
AGTTCCCAGGCGAGGTATATGGAATGGTACTTAACCTTGAAGAGGATAATGTTGGTGCCGTTTTACTTGGTGATTCAAGA
AATGTTAATGAAGGCGATACTGTTAAGACAACTGGACGAGTTGTTGAGGTTCCAGTTGGTGACGCATTGACAGGACGAGT
TGTCAATGCATTAGGACAGCCTATTGATGGCAAAGGACCAATCGTTACAGATAAGTATCGTAAGATTGAGAGAGTTGCAT
CAGGCGTTATTACAAGAAAGTCAGTAAGCGTACCACTTCAGACAGGTATTAAGGCTATTGATGCCATGGTTCCTATCGGA
AGAGGACAGAGAGAGCTTATTATCGGTGACCGTCAGACAGGTAAGACGGCTATCGCTATTGATACTATTATTAACCAGAA
GGGTCAGGGCGTACATTGTATATATGTTGCCATCGGACAGAAGGCTTCAACTGTTGCAAGTATTGTTAAGACTCTTGAAG
AGTACGGTGCAATGGCATATACAACTGTAGTTGCATCTACAGCCAGCGAGCTTGCTCCTTTACAGTATATCGCTCCTTAT
TCAGGATGCGCTATTGGTGAAGAGTGGATGGAGAACGGTGGAGATGTATTAGTTGTTTACGATGATTTAAGTAAGCATGC
TGCAGCATACAGAACACTTTCACTTCTTCTTAAGAGAGCACCTGGACGAGAGGCTTATCCTGGTGATGTATTCTATCTTC
ATTCAAGACTTCTTGAGAGAGCAGCCAGAATGTCAGATGAATACGGTGGAGGTTCACTTACAGCACTTCCAATTATTGAA
ACTCAGGCAGGAGATGTTTCAGCATATATTCCTACTAATGTTATTTCTATCACAGATGGACAGATATATCTTGAGACAGA
AATGTTTAATTCAGGTTTCAGACCAGCTATTAATGCCGGTTTGTCTGTATCACGAGTTGGTGGTTCAGCACAGATTAAGG
CTATTAAGAAGATTGCTGCTCCTATCCGTACAGAGCTTGCCCAGTACAGAGAGCTTGCATCATTCTCACAGTTCGGTTCA
GAGCTTGATGCTGATACTAAGGAAAAGCTTGCACAGGGTGAAAGAATCAGAGAGATGCTTAAGCAGCCACAGTACAAGCC
AATGCCGGTTGAGTATCAGGTTATAATCATTTATGCAGTTACCAAGAAGTATGTTATCGATATAGATGTTGACAGAATTC
TTGATTTTGAGCAGGGATTATTCGACTTTATTGATACCAAGTATCCACAGATTCCAGAGTCTATCAAGGAGACTAAGGAA
CTGACAGCAGATAATGAGAAGGCACTTATAGCTGCCATCGAGGAGTTTAAGAAAACATTTATCCAGTAA

Upstream 100 bases:

>100_bases
GCATAAAATAGACGAACTTTCCAGAAGTCTGATGAAGATTCAGTTATAGGAATATCAGACAGGTTAGTTTAATTAATCAG
AAAGCGGGTGCATAGAGCTA

Downstream 100 bases:

>100_bases
ATGTTTTGGAATGGAGGTAATAATTTATGGCCTCAATGAGAGACATAAAAAGACGCAGAGATAGTATTCAAAGTACCGGT
CAGATTACCAAAGCCATGAA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MNLRPEEISSVIKEQIKRYSTELEVSDVGTVIQVADGIARIHGLEKAMQGELLEFPGEVYGMVLNLEEDNVGAVLLGDSR
NVNEGDTVKTTGRVVEVPVGDALTGRVVNALGQPIDGKGPIVTDKYRKIERVASGVITRKSVSVPLQTGIKAIDAMVPIG
RGQRELIIGDRQTGKTAIAIDTIINQKGQGVHCIYVAIGQKASTVASIVKTLEEYGAMAYTTVVASTASELAPLQYIAPY
SGCAIGEEWMENGGDVLVVYDDLSKHAAAYRTLSLLLKRAPGREAYPGDVFYLHSRLLERAARMSDEYGGGSLTALPIIE
TQAGDVSAYIPTNVISITDGQIYLETEMFNSGFRPAINAGLSVSRVGGSAQIKAIKKIAAPIRTELAQYRELASFSQFGS
ELDADTKEKLAQGERIREMLKQPQYKPMPVEYQVIIIYAVTKKYVIDIDVDRILDFEQGLFDFIDTKYPQIPESIKETKE
LTADNEKALIAAIEEFKKTFIQ

Sequences:

>Translated_502_residues
MNLRPEEISSVIKEQIKRYSTELEVSDVGTVIQVADGIARIHGLEKAMQGELLEFPGEVYGMVLNLEEDNVGAVLLGDSR
NVNEGDTVKTTGRVVEVPVGDALTGRVVNALGQPIDGKGPIVTDKYRKIERVASGVITRKSVSVPLQTGIKAIDAMVPIG
RGQRELIIGDRQTGKTAIAIDTIINQKGQGVHCIYVAIGQKASTVASIVKTLEEYGAMAYTTVVASTASELAPLQYIAPY
SGCAIGEEWMENGGDVLVVYDDLSKHAAAYRTLSLLLKRAPGREAYPGDVFYLHSRLLERAARMSDEYGGGSLTALPIIE
TQAGDVSAYIPTNVISITDGQIYLETEMFNSGFRPAINAGLSVSRVGGSAQIKAIKKIAAPIRTELAQYRELASFSQFGS
ELDADTKEKLAQGERIREMLKQPQYKPMPVEYQVIIIYAVTKKYVIDIDVDRILDFEQGLFDFIDTKYPQIPESIKETKE
LTADNEKALIAAIEEFKKTFIQ
>Mature_502_residues
MNLRPEEISSVIKEQIKRYSTELEVSDVGTVIQVADGIARIHGLEKAMQGELLEFPGEVYGMVLNLEEDNVGAVLLGDSR
NVNEGDTVKTTGRVVEVPVGDALTGRVVNALGQPIDGKGPIVTDKYRKIERVASGVITRKSVSVPLQTGIKAIDAMVPIG
RGQRELIIGDRQTGKTAIAIDTIINQKGQGVHCIYVAIGQKASTVASIVKTLEEYGAMAYTTVVASTASELAPLQYIAPY
SGCAIGEEWMENGGDVLVVYDDLSKHAAAYRTLSLLLKRAPGREAYPGDVFYLHSRLLERAARMSDEYGGGSLTALPIIE
TQAGDVSAYIPTNVISITDGQIYLETEMFNSGFRPAINAGLSVSRVGGSAQIKAIKKIAAPIRTELAQYRELASFSQFGS
ELDADTKEKLAQGERIREMLKQPQYKPMPVEYQVIIIYAVTKKYVIDIDVDRILDFEQGLFDFIDTKYPQIPESIKETKE
LTADNEKALIAAIEEFKKTFIQ

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=502, Percent_Identity=56.1752988047809, Blast_Score=576, Evalue=1e-164,
Organism=Homo sapiens, GI4757810, Length=502, Percent_Identity=56.1752988047809, Blast_Score=576, Evalue=1e-164,
Organism=Homo sapiens, GI19913426, Length=298, Percent_Identity=28.8590604026846, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI19913428, Length=299, Percent_Identity=29.0969899665552, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI32189394, Length=370, Percent_Identity=23.5135135135135, Blast_Score=89, Evalue=9e-18,
Organism=Escherichia coli, GI1790172, Length=510, Percent_Identity=56.2745098039216, Blast_Score=597, Evalue=1e-172,
Organism=Escherichia coli, GI1790170, Length=366, Percent_Identity=25.1366120218579, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788251, Length=280, Percent_Identity=27.1428571428571, Blast_Score=92, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71988063, Length=502, Percent_Identity=56.3745019920319, Blast_Score=575, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI71988080, Length=502, Percent_Identity=56.3745019920319, Blast_Score=574, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI71988074, Length=502, Percent_Identity=52.390438247012, Blast_Score=518, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI17510931, Length=371, Percent_Identity=27.2237196765499, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=323, Percent_Identity=27.8637770897833, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=370, Percent_Identity=22.972972972973, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17509265, Length=51, Percent_Identity=60.7843137254902, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=505, Percent_Identity=56.2376237623762, Blast_Score=577, Evalue=1e-165,
Organism=Saccharomyces cerevisiae, GI6319603, Length=298, Percent_Identity=29.1946308724832, Blast_Score=113, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6322581, Length=397, Percent_Identity=24.9370277078086, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=56.039603960396, Blast_Score=567, Evalue=1e-162,
Organism=Drosophila melanogaster, GI281361666, Length=353, Percent_Identity=27.4787535410765, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24646341, Length=353, Percent_Identity=27.4787535410765, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI17136796, Length=353, Percent_Identity=27.4787535410765, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24638766, Length=370, Percent_Identity=24.5945945945946, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI28574560, Length=422, Percent_Identity=23.9336492890995, Blast_Score=87, Evalue=4e-17,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54816; Mature: 54816

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRPEEISSVIKEQIKRYSTELEVSDVGTVIQVADGIARIHGLEKAMQGELLEFPGEVY
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCE
GMVLNLEEDNVGAVLLGDSRNVNEGDTVKTTGRVVEVPVGDALTGRVVNALGQPIDGKGP
EEEEEECCCCCCEEEECCCCCCCCCCCEEECCCEEEECCCCHHHHHHHHHHCCCCCCCCC
IVTDKYRKIERVASGVITRKSVSVPLQTGIKAIDAMVPIGRGQRELIIGDRQTGKTAIAI
EECHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEE
DTIINQKGQGVHCIYVAIGQKASTVASIVKTLEEYGAMAYTTVVASTASELAPLQYIAPY
EHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHCCCC
SGCAIGEEWMENGGDVLVVYDDLSKHAAAYRTLSLLLKRAPGREAYPGDVFYLHSRLLER
CCCCCCHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
AARMSDEYGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIYLETEMFNSGFRPAINAG
HHHCCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEECCEEEEEEEHHCCCCCHHHHCC
LSVSRVGGSAQIKAIKKIAAPIRTELAQYRELASFSQFGSELDADTKEKLAQGERIREML
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
KQPQYKPMPVEYQVIIIYAVTKKYVIDIDVDRILDFEQGLFDFIDTKYPQIPESIKETKE
HCCCCCCCCCEEEEEEEEEECCCEEEEECHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LTADNEKALIAAIEEFKKTFIQ
HCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLRPEEISSVIKEQIKRYSTELEVSDVGTVIQVADGIARIHGLEKAMQGELLEFPGEVY
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCE
GMVLNLEEDNVGAVLLGDSRNVNEGDTVKTTGRVVEVPVGDALTGRVVNALGQPIDGKGP
EEEEEECCCCCCEEEECCCCCCCCCCCEEECCCEEEECCCCHHHHHHHHHHCCCCCCCCC
IVTDKYRKIERVASGVITRKSVSVPLQTGIKAIDAMVPIGRGQRELIIGDRQTGKTAIAI
EECHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEE
DTIINQKGQGVHCIYVAIGQKASTVASIVKTLEEYGAMAYTTVVASTASELAPLQYIAPY
EHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHCCCC
SGCAIGEEWMENGGDVLVVYDDLSKHAAAYRTLSLLLKRAPGREAYPGDVFYLHSRLLER
CCCCCCHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
AARMSDEYGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIYLETEMFNSGFRPAINAG
HHHCCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEECCEEEEEEEHHCCCCCHHHHCC
LSVSRVGGSAQIKAIKKIAAPIRTELAQYRELASFSQFGSELDADTKEKLAQGERIREML
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
KQPQYKPMPVEYQVIIIYAVTKKYVIDIDVDRILDFEQGLFDFIDTKYPQIPESIKETKE
HCCCCCCCCCEEEEEEEEEECCCEEEEECHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LTADNEKALIAAIEEFKKTFIQ
HCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA