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The map label for this gene is cysW [H]

Identifier: 238917803

GI number: 238917803

Start: 1948045

End: 1948890

Strand: Reverse

Name: cysW [H]

Synonym: EUBELI_01884

Alternate gene names: 238917803

Gene position: 1948890-1948045 (Counterclockwise)

Preceding gene: 238917804

Following gene: 238917802

Centisome position: 90.89

GC content: 41.96

Gene sequence:

>846_bases
ATGAACATCAGAAAAGATTCAGGTCCGTTAAAATGGATTCTAATAGGTATAAGTGTGTTGTTTTTATTTGTGATGCTTAT
TCTGCCCCTCAGCTATGTAATGTATACAGCATTTTCTAAGGGCATAAAGGTGTTTCTGGCAGCTGTTACCGACAAATACG
CACTTCATTCGATTAAGCTGACAATAGAGGTTTCGCTTATTGCGGTTGTGTGTAACACATTTTTCGGAATATTTGCTTCA
TGGCTTATTACGAAATTCCAGTTTAAGGGCAAGAAGATTATATCTACTTTAATAGATTTACCACTCACAGTTTCACCGAT
TATAGCAGGTCTTATATATGTGCTTACATTCGGTAGACAGAGTTTTATATATCCATATCTTAAGGCTATGGGAGTAAGAA
TTATATTCGCAGTTCCGGGTATCGTGCTTGCGACTATATTTGTAACGTTTCCATTCATATCAAGGGAGCTGATACCGGTT
CTTACCTCGCAGGGAACTGACGAGGAGGAGGCTGCAGCGCTTATGGGTGCAAATGGCTGGACTATATTCTGGAAGGTTAC
ATTCCCACATATCAAATGGCCGCTTCTCTACGGTATTGTACTGTGTACAGCGAGAGCAATGGGCGAGTTTGGCGCGGTAT
CCGTTCTTTCAGGACATTTGCGCGGAAGAACTAACACGATGCCGTTGTATATTGAACTTCTGTATCAGGGATATGATTTT
ACGGGAGCATTTGCAGTGTCAGCAATTCTTGTGCTGATGGCGGTTATTATACTTGTGCTTCGAAGTGTACTTGAATACAA
GGGGCAGCAGGCAGCTAAGGCAGAGAAAGAGCGGCAGGAAGGATAG

Upstream 100 bases:

>100_bases
TAATGCTTTTTATCGCATTTATTATTCTCTTTATAAATGCAGTGTTACAGAGCAGGACATCGAAGATTGTAAGTGGAATT
TCATAGAAAGGGGTTAGCGT

Downstream 100 bases:

>100_bases
AAACGCACTACAACAGAAAGGCGGAACAGATTATGGCAGAATTACAGCAGGACACAGAAAAATATGTAGAGCTTCGTAAT
ATCAATAAGACATATGGCAC

Product: sulfate transport system permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MNIRKDSGPLKWILIGISVLFLFVMLILPLSYVMYTAFSKGIKVFLAAVTDKYALHSIKLTIEVSLIAVVCNTFFGIFAS
WLITKFQFKGKKIISTLIDLPLTVSPIIAGLIYVLTFGRQSFIYPYLKAMGVRIIFAVPGIVLATIFVTFPFISRELIPV
LTSQGTDEEEAAALMGANGWTIFWKVTFPHIKWPLLYGIVLCTARAMGEFGAVSVLSGHLRGRTNTMPLYIELLYQGYDF
TGAFAVSAILVLMAVIILVLRSVLEYKGQQAAKAEKERQEG

Sequences:

>Translated_281_residues
MNIRKDSGPLKWILIGISVLFLFVMLILPLSYVMYTAFSKGIKVFLAAVTDKYALHSIKLTIEVSLIAVVCNTFFGIFAS
WLITKFQFKGKKIISTLIDLPLTVSPIIAGLIYVLTFGRQSFIYPYLKAMGVRIIFAVPGIVLATIFVTFPFISRELIPV
LTSQGTDEEEAAALMGANGWTIFWKVTFPHIKWPLLYGIVLCTARAMGEFGAVSVLSGHLRGRTNTMPLYIELLYQGYDF
TGAFAVSAILVLMAVIILVLRSVLEYKGQQAAKAEKERQEG
>Mature_281_residues
MNIRKDSGPLKWILIGISVLFLFVMLILPLSYVMYTAFSKGIKVFLAAVTDKYALHSIKLTIEVSLIAVVCNTFFGIFAS
WLITKFQFKGKKIISTLIDLPLTVSPIIAGLIYVLTFGRQSFIYPYLKAMGVRIIFAVPGIVLATIFVTFPFISRELIPV
LTSQGTDEEEAAALMGANGWTIFWKVTFPHIKWPLLYGIVLCTARAMGEFGAVSVLSGHLRGRTNTMPLYIELLYQGYDF
TGAFAVSAILVLMAVIILVLRSVLEYKGQQAAKAEKERQEG

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=281, Percent_Identity=47.6868327402135, Blast_Score=273, Evalue=8e-75,
Organism=Escherichia coli, GI1788764, Length=202, Percent_Identity=30.1980198019802, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1786980, Length=226, Percent_Identity=30.9734513274336, Blast_Score=88, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31194; Mature: 31194

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRKDSGPLKWILIGISVLFLFVMLILPLSYVMYTAFSKGIKVFLAAVTDKYALHSIKL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
TIEVSLIAVVCNTFFGIFASWLITKFQFKGKKIISTLIDLPLTVSPIIAGLIYVLTFGRQ
EEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCH
SFIYPYLKAMGVRIIFAVPGIVLATIFVTFPFISRELIPVLTSQGTDEEEAAALMGANGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCC
TIFWKVTFPHIKWPLLYGIVLCTARAMGEFGAVSVLSGHLRGRTNTMPLYIELLYQGYDF
EEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
TGAFAVSAILVLMAVIILVLRSVLEYKGQQAAKAEKERQEG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNIRKDSGPLKWILIGISVLFLFVMLILPLSYVMYTAFSKGIKVFLAAVTDKYALHSIKL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
TIEVSLIAVVCNTFFGIFASWLITKFQFKGKKIISTLIDLPLTVSPIIAGLIYVLTFGRQ
EEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCH
SFIYPYLKAMGVRIIFAVPGIVLATIFVTFPFISRELIPVLTSQGTDEEEAAALMGANGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCC
TIFWKVTFPHIKWPLLYGIVLCTARAMGEFGAVSVLSGHLRGRTNTMPLYIELLYQGYDF
EEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
TGAFAVSAILVLMAVIILVLRSVLEYKGQQAAKAEKERQEG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]