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The map label for this gene is accA [H]

Identifier: 238917645

GI number: 238917645

Start: 1791776

End: 1792567

Strand: Reverse

Name: accA [H]

Synonym: EUBELI_01724

Alternate gene names: 238917645

Gene position: 1792567-1791776 (Counterclockwise)

Preceding gene: 238917646

Following gene: 238917644

Centisome position: 83.6

GC content: 40.15

Gene sequence:

>792_bases
ATGAGCAGTGAAAATGTTTTAACACCATATGAGAAAGTCCTTGCAGCCAGAAAAAGTGACCGTCCGGATATTATGAAATA
CATAGAAGTGCTTTTCGATGATTTTATAGAAATGCATGGTGACAGATACTATAAAGATGATAAAAGCCTTGTTGCAGGAA
TTGCTTCATTTAATGGAAAAACGGTAACTGTTATTGGAAACCGTAAAGGAAAGAATATAGAAGAGAATATAAGATATAAC
TTCGGAATGGCGTCACCTGAAGGGTATAGAAAAGCAGTCCGTGTTATGAAACAGGCTGAAAAATTCAGGAGACCTGTCAT
AACATTTGTTGACACGCCAGGTGCATATCCAGGCATGGAAGCAGAAAGCAACGGACAGAGTAATGCGATTGCGGGAAGTA
TAGCAGCAATGCTTAAGCTTACAGTACCTGTTATATCAGTAATCACAGGTGAAGGCGGAAGTGGCGGTGCATTGGCACTG
GCAGCAGCCGACAGGGTGTATATGCTTGAAAATGCAGTATATTCGATTCTGTCTCCGGAAGGTTTTGCGTCAATAATATA
TAAGGATGCTAAGAAAGCACCACAGGCAAGTGAGATTATGAAGCTTACTGCACAGGAGCTTTTTACTGCCGGACTCGTTG
ATGGTGTAATTGCAGAAGGAGACAGGTGTTTTTCAGATATAGCAAGAATGTTAGAAAAAGAACTCGGAATTCTTGGCAGG
ATGAAATCAAAAGAGCTTGTTAATTCAAGATATGACAAATTCAGGAATATAGACAGGGGAGAGATAAAGTGA

Upstream 100 bases:

>100_bases
TGTTAGAACATGGCATGATAGATATGATAGTTGACAGAAAAGATATGAAGCAGACTTTATCAAAGATATTGAAAATGCAT
GTGAATACCGGAGGAGAAGC

Downstream 100 bases:

>100_bases
AAGGCATTCAGATAGTGTCCACAGGGAAAGCACTCCCAGAAGAGATAATTACGAATGATGACTTAAGCCGGATTGTTGAT
ACAAATGATGAATGGATAAC

Product: acetyl-CoA carboxylase carboxyl transferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSSENVLTPYEKVLAARKSDRPDIMKYIEVLFDDFIEMHGDRYYKDDKSLVAGIASFNGKTVTVIGNRKGKNIEENIRYN
FGMASPEGYRKAVRVMKQAEKFRRPVITFVDTPGAYPGMEAESNGQSNAIAGSIAAMLKLTVPVISVITGEGGSGGALAL
AAADRVYMLENAVYSILSPEGFASIIYKDAKKAPQASEIMKLTAQELFTAGLVDGVIAEGDRCFSDIARMLEKELGILGR
MKSKELVNSRYDKFRNIDRGEIK

Sequences:

>Translated_263_residues
MSSENVLTPYEKVLAARKSDRPDIMKYIEVLFDDFIEMHGDRYYKDDKSLVAGIASFNGKTVTVIGNRKGKNIEENIRYN
FGMASPEGYRKAVRVMKQAEKFRRPVITFVDTPGAYPGMEAESNGQSNAIAGSIAAMLKLTVPVISVITGEGGSGGALAL
AAADRVYMLENAVYSILSPEGFASIIYKDAKKAPQASEIMKLTAQELFTAGLVDGVIAEGDRCFSDIARMLEKELGILGR
MKSKELVNSRYDKFRNIDRGEIK
>Mature_262_residues
SSENVLTPYEKVLAARKSDRPDIMKYIEVLFDDFIEMHGDRYYKDDKSLVAGIASFNGKTVTVIGNRKGKNIEENIRYNF
GMASPEGYRKAVRVMKQAEKFRRPVITFVDTPGAYPGMEAESNGQSNAIAGSIAAMLKLTVPVISVITGEGGSGGALALA
AADRVYMLENAVYSILSPEGFASIIYKDAKKAPQASEIMKLTAQELFTAGLVDGVIAEGDRCFSDIARMLEKELGILGRM
KSKELVNSRYDKFRNIDRGEIK

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family [H]

Homologues:

Organism=Escherichia coli, GI1786382, Length=256, Percent_Identity=44.921875, Blast_Score=233, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI25147362, Length=267, Percent_Identity=27.3408239700375, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25147359, Length=267, Percent_Identity=27.3408239700375, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001095
- InterPro:   IPR011763 [H]

Pfam domain/function: PF03255 ACCA [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 28903; Mature: 28771

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSENVLTPYEKVLAARKSDRPDIMKYIEVLFDDFIEMHGDRYYKDDKSLVAGIASFNGK
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
TVTVIGNRKGKNIEENIRYNFGMASPEGYRKAVRVMKQAEKFRRPVITFVDTPGAYPGME
EEEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
AESNGQSNAIAGSIAAMLKLTVPVISVITGEGGSGGALALAAADRVYMLENAVYSILSPE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCC
GFASIIYKDAKKAPQASEIMKLTAQELFTAGLVDGVIAEGDRCFSDIARMLEKELGILGR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
MKSKELVNSRYDKFRNIDRGEIK
CHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SSENVLTPYEKVLAARKSDRPDIMKYIEVLFDDFIEMHGDRYYKDDKSLVAGIASFNGK
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
TVTVIGNRKGKNIEENIRYNFGMASPEGYRKAVRVMKQAEKFRRPVITFVDTPGAYPGME
EEEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
AESNGQSNAIAGSIAAMLKLTVPVISVITGEGGSGGALALAAADRVYMLENAVYSILSPE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCC
GFASIIYKDAKKAPQASEIMKLTAQELFTAGLVDGVIAEGDRCFSDIARMLEKELGILGR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
MKSKELVNSRYDKFRNIDRGEIK
CHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]