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The map label for this gene is fabH [H]

Identifier: 238917644

GI number: 238917644

Start: 1790844

End: 1791779

Strand: Reverse

Name: fabH [H]

Synonym: EUBELI_01723

Alternate gene names: 238917644

Gene position: 1791779-1790844 (Counterclockwise)

Preceding gene: 238917645

Following gene: 238917643

Centisome position: 83.56

GC content: 39.42

Gene sequence:

>936_bases
GTGAAAGGCATTCAGATAGTGTCCACAGGGAAAGCACTCCCAGAAGAGATAATTACGAATGATGACTTAAGCCGGATTGT
TGATACAAATGATGAATGGATAACAACAAGAACAGGTATTAAGAAAAGATACAGATGTACACAGGAAAATACTACATCAC
TTGCAGTCAGAGCAGCATATGAAGCGGTAGAGGCATCAGGTGTGGATATTGCAGAAATAGGTGCAGTTATAGTTGCAACT
TCAACTGCAGATAATGCATTTCCATCTACTGCAGCAATTGTACAGAAGGAGCTTGGATTGGCTGAGAATGTACTTGCATT
TGATTTAAGCAGTGCATGTACAGGTTTTCTGCATGCATTAAATGTTGGACAGGCACTGTTTAACAGCACTGATTATAAAT
ACATACTGCTTATTGGAAGCGAGCAGATGTCTAAGATATTAGATTATACAGACCGCTCAACATGCGTGCTTTTTGGAGAT
GGTGCAGGTGCAGTTCTTATAAAAGCGGCTGACAATATGTATAGACAGATTAATTACACAAGAGGCGATACTGATGTACT
TGTATGCAGAGGTATAGGTGCACAGGATGCATATGTAAAGATGAATGGAAATGCGGTGTTCCGTTTTGCAGTTGATGTTC
TTAAACAGGGAATTGATGAAATATTGAAAAAATCGGACATGACACTTGATGACATAGATTATATTGTGTGCCATCAGGCT
AATGAAAGAATTATCAATCATGTAAAGAAAAAATATCCGGGACATGAAGATAAGTTCTATATAAATATAGCGGAATACGG
TAATACATCAGCGGCAAGTATCCCAATAGCACTAGATGAGTTAGCACAAAGAGGATGCTTTGACAAAGGCAGAAAGCTGA
TTCTTGCGGGCTTTGGAGCGGGGCTTAGCTGGAGCAGTGCTTTGATAGAGACATAA

Upstream 100 bases:

>100_bases
TGTTAGAAAAAGAACTCGGAATTCTTGGCAGGATGAAATCAAAAGAGCTTGTTAATTCAAGATATGACAAATTCAGGAAT
ATAGACAGGGGAGAGATAAA

Downstream 100 bases:

>100_bases
TAAGGAGCAGCATAATGAGATTAGATAAGATGTTAGGAATAAAATATCCGTTTATACAGGGCGGAATGGCTAATATTGCA
ACAGGAGAATTTGCAGCTGC

Product: 3-oxoacyl-[acyl-carrier-protein] synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKGIQIVSTGKALPEEIITNDDLSRIVDTNDEWITTRTGIKKRYRCTQENTTSLAVRAAYEAVEASGVDIAEIGAVIVAT
STADNAFPSTAAIVQKELGLAENVLAFDLSSACTGFLHALNVGQALFNSTDYKYILLIGSEQMSKILDYTDRSTCVLFGD
GAGAVLIKAADNMYRQINYTRGDTDVLVCRGIGAQDAYVKMNGNAVFRFAVDVLKQGIDEILKKSDMTLDDIDYIVCHQA
NERIINHVKKKYPGHEDKFYINIAEYGNTSAASIPIALDELAQRGCFDKGRKLILAGFGAGLSWSSALIET

Sequences:

>Translated_311_residues
MKGIQIVSTGKALPEEIITNDDLSRIVDTNDEWITTRTGIKKRYRCTQENTTSLAVRAAYEAVEASGVDIAEIGAVIVAT
STADNAFPSTAAIVQKELGLAENVLAFDLSSACTGFLHALNVGQALFNSTDYKYILLIGSEQMSKILDYTDRSTCVLFGD
GAGAVLIKAADNMYRQINYTRGDTDVLVCRGIGAQDAYVKMNGNAVFRFAVDVLKQGIDEILKKSDMTLDDIDYIVCHQA
NERIINHVKKKYPGHEDKFYINIAEYGNTSAASIPIALDELAQRGCFDKGRKLILAGFGAGLSWSSALIET
>Mature_311_residues
MKGIQIVSTGKALPEEIITNDDLSRIVDTNDEWITTRTGIKKRYRCTQENTTSLAVRAAYEAVEASGVDIAEIGAVIVAT
STADNAFPSTAAIVQKELGLAENVLAFDLSSACTGFLHALNVGQALFNSTDYKYILLIGSEQMSKILDYTDRSTCVLFGD
GAGAVLIKAADNMYRQINYTRGDTDVLVCRGIGAQDAYVKMNGNAVFRFAVDVLKQGIDEILKKSDMTLDDIDYIVCHQA
NERIINHVKKKYPGHEDKFYINIAEYGNTSAASIPIALDELAQRGCFDKGRKLILAGFGAGLSWSSALIET

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=318, Percent_Identity=38.6792452830189, Blast_Score=224, Evalue=5e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 33832; Mature: 33832

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGIQIVSTGKALPEEIITNDDLSRIVDTNDEWITTRTGIKKRYRCTQENTTSLAVRAAY
CCCCEEEECCCCCHHHHHCCCCHHHHHCCCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHH
EAVEASGVDIAEIGAVIVATSTADNAFPSTAAIVQKELGLAENVLAFDLSSACTGFLHAL
HHHHCCCCCHHHCCEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
NVGQALFNSTDYKYILLIGSEQMSKILDYTDRSTCVLFGDGAGAVLIKAADNMYRQINYT
HHHHHHHCCCCCEEEEEECCHHHHHHHCCCCCCEEEEEECCCCEEEEEEHHHHHHHEECC
RGDTDVLVCRGIGAQDAYVKMNGNAVFRFAVDVLKQGIDEILKKSDMTLDDIDYIVCHQA
CCCCCEEEEECCCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHCCCCHHHCCEEEEECC
NERIINHVKKKYPGHEDKFYINIAEYGNTSAASIPIALDELAQRGCFDKGRKLILAGFGA
HHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCEEHHHHHHCCCHHCCCEEEEEECCC
GLSWSSALIET
CCCCCHHHHCC
>Mature Secondary Structure
MKGIQIVSTGKALPEEIITNDDLSRIVDTNDEWITTRTGIKKRYRCTQENTTSLAVRAAY
CCCCEEEECCCCCHHHHHCCCCHHHHHCCCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHH
EAVEASGVDIAEIGAVIVATSTADNAFPSTAAIVQKELGLAENVLAFDLSSACTGFLHAL
HHHHCCCCCHHHCCEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
NVGQALFNSTDYKYILLIGSEQMSKILDYTDRSTCVLFGDGAGAVLIKAADNMYRQINYT
HHHHHHHCCCCCEEEEEECCHHHHHHHCCCCCCEEEEEECCCCEEEEEEHHHHHHHEECC
RGDTDVLVCRGIGAQDAYVKMNGNAVFRFAVDVLKQGIDEILKKSDMTLDDIDYIVCHQA
CCCCCEEEEECCCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHCCCCHHHCCEEEEECC
NERIINHVKKKYPGHEDKFYINIAEYGNTSAASIPIALDELAQRGCFDKGRKLILAGFGA
HHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCEEHHHHHHCCCHHCCCEEEEEECCC
GLSWSSALIET
CCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]