| Definition | Eubacterium eligens ATCC 27750 chromosome, complete genome. |
|---|---|
| Accession | NC_012778 |
| Length | 2,144,190 |
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The map label for this gene is pbpA [H]
Identifier: 238917521
GI number: 238917521
Start: 1654857
End: 1657550
Strand: Direct
Name: pbpA [H]
Synonym: EUBELI_01600
Alternate gene names: 238917521
Gene position: 1654857-1657550 (Clockwise)
Preceding gene: 238917513
Following gene: 238917539
Centisome position: 77.18
GC content: 38.57
Gene sequence:
>2694_bases ATGAATTATGGTGATAAAGGCATAAAACAAAAGAAAAAGCTGCTCAATTCAGCTACTACCAAGCTTGGCACCAAATTAGG TATATTTTTTATAAAGCTGGCTCTGGTCGGAATAATAGCATTAGTTGTAGCAGGTTCATGCCTTGTATTCGGTTCATTTC AGGGAATTATAGAAAACGCTCCTGATATAGCTTCTATTAATGTTTCGCCCGAAGGATTTGCGACCAAAATATATGATACT GATAATAATGAAATACAGACACTTTCATCTGCTGGAGCTAACAGGACTTATGTTACCATTGACCAGATTCCTTTAAATCT TCAGCATGCATTTATTGCTATTGAGGATGAACGTTTTTATGAGCATAACGGCATAGACATGAAAGGTATTTTAAGAGCTG CATCTATCACTCTTTCTTCAGGACACATGTCGCAGGGTGCCAGTACAATTACACAGCAGCTGATTAAGAATAATGTATTT AATGCCTACAACGAATCTGACATTGAAAAGATAAAACGAAAAGTACAGGAACAGTATCTTGCCATAAAGCTTGAAACTGT AATGTCAAAGAAATCAATACTTGAGAACTATCTTAATACTATTAATCTTGGAAACGGCTATTATGGTGTCCAGGCTGCTG CGAAAGGTTACTTTAATAAAGATGTATCTGAGCTTTCATTAAGCGAGTGCGCAGTTATTGCCTCTATCACTAAAAGTCCT ACCGGTCTTAATCCAATAAGACACGCTGACAGAAACAGAGACAGACAAAGCCAGGTTCTTCTTAATATGAAAGATCAGGG ATATATTTCACAGGCTGAATATGATGATGCTCTTACAGATGATGTATATGCAAGACTTGAAGGCATTGAACTTGCCGGAA CATCTACAACTACCTATTCATATTTTGTAGATGAACTTATTAACCAGCTTACCTCAGATCTTATGTCACAGAAAGGCTAT ACAGAATCTCAGGCAACAAGCCTTATATACCGCGGAGGACTTCAGGTTTATTCAACGCAGGATACAATGATGCAGCAGGT TGCTGATGATGTGATTAATGACCCTGATAATTACAATGATAATACACATTTTTCAATTAACTATGCTTTAACTGTCAAGC AGACAGATGGGACATTTTCGTATTATTCACATAACTCAATGGCTAACTGGTATACCAAAAAACTCGGTGACACAAGTTTC AGCCTCACATTGACTGATGAGGATGCTGCCAGAGCATATGTTGAAGCATATAAAGAAGAACTCCTTAAGGAAGGGGGAGA AGTTTATTCAGAAACGCTTACCTTTACATTACAGCCACAGATTTCATTTACAATAATGGATCAGACCAATGGACATGTTA AAGTAATGGTTGGTGGGCGCGGCGATAAAACTCTTAACCGAAGCTTAAACCGTGCTTCTAATGATATTGCAAGACAACCG GGCTCAAGTATTAAACCACTTGTGGCATATGGCCCCGCTCTTGATACAGGAACATATACACTTGCTTCTGCCATTGATGA TGCACCTTATTATTACTCTGGCACAGATGCCAAGCTTGTAACTAATTTCACAAAAGGAGAATATCGTGGTCTGATTACAT TAAGACAGGCACTTACAATTTCACAGAATGTACCTGCTGTTAAGATTCTTACAAAGCTGACTCCTCAGGTCGGATACAAT TATCTTGAGAAATTCGGTATATCAACACTTGTTTCTCCTAAGAATGCAATTAACGGTGCACATGATGTTGTCCAGTCACT TGCACTTGGTGGTATGACCCGTGGTGTTTCCAATATCGATATGTGTGCTGCTTATGCTGCTATCGCTAACAAGGGAACCT ATACAAAACCAGTTTATTACACAAAGGTACTTGATTCAGATGGCAATATTATCATTGATAATACCATTCCAGAAACGCAT AAGGTTCTTAATGAGAACTCAGACTGGCTCCTTATACAGGGTCTCCGTTCAGTTGCAACTGATGGTACAGCACGTTCAGC AAACTTTTCAAGCCAGCCTGTAGCAGGTAAGACAGGTACAACACAGTATGACAGCGACAGATGGTTCTGTGGCTTCACTC CATATTATACAGCCACAATATGGGTTGGATATGATGACAATTCAAGAGAGCTTGGAAATGTTGTAAATCATAATATTATT TGGCGTTCAATTATGCAGACAATCCATGAAAACCTTAATCTTCCAACCGGAACATATGAACAGCCTTCTGGTATTGTAGA AGCATCTGTCTGCTCTAAATCAGGCCTTCTTCCTGTTGAAGGATTATGTGATCAGGATTCTGAAGGAAACTGCATAATAA CTGAATATTTTACAGAAGACACAGTTCCAACAGAATACTGTACAACACATACCAAAGTAACTTTCTGTAATGTATCAGGA GATATTGCTACATCAGGTTGTCCAAGCACAACAACCAAAATTATGAGAAAGAAATCTTCTGCTGATAAGCTTGGTGATGA TAAGGAAGGCTCGGAATTCAAGACATGGGATGCTGATATTTCAATAACAGACACTGAATTATCTAAGCTATGTACTCTTC ACAGTGCCACAACAAAGCCAACCAAAGCAACAAATACTAATAAAAGTACTGAGGAAACTTCATCTGCAACGCAGTCGGAA ACTAAAACAGATAAAAGTACATCCTCATCGTCTTCATCAACCAGACGGCCATAA
Upstream 100 bases:
>100_bases ATATTTTTTCCTTTTCCAAATCACTCGGCACAACTCCAATTATTTGCCTGTGCCTTCTTTTTATGATATAATATCATGAC TTTATTAAGGAGGACAATAT
Downstream 100 bases:
>100_bases TTAATTTAAAATCACAAAAAAGAGATGTCAGATGATTTCTATTCTGGCATCTCTTTTCATATCTACTCTTTTTTCATCTT AGGTTCAAATATAAGCGACG
Product: peptidoglycan glycosyltransferase
Products: NA
Alternate protein names: PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 897; Mature: 897
Protein sequence:
>897_residues MNYGDKGIKQKKKLLNSATTKLGTKLGIFFIKLALVGIIALVVAGSCLVFGSFQGIIENAPDIASINVSPEGFATKIYDT DNNEIQTLSSAGANRTYVTIDQIPLNLQHAFIAIEDERFYEHNGIDMKGILRAASITLSSGHMSQGASTITQQLIKNNVF NAYNESDIEKIKRKVQEQYLAIKLETVMSKKSILENYLNTINLGNGYYGVQAAAKGYFNKDVSELSLSECAVIASITKSP TGLNPIRHADRNRDRQSQVLLNMKDQGYISQAEYDDALTDDVYARLEGIELAGTSTTTYSYFVDELINQLTSDLMSQKGY TESQATSLIYRGGLQVYSTQDTMMQQVADDVINDPDNYNDNTHFSINYALTVKQTDGTFSYYSHNSMANWYTKKLGDTSF SLTLTDEDAARAYVEAYKEELLKEGGEVYSETLTFTLQPQISFTIMDQTNGHVKVMVGGRGDKTLNRSLNRASNDIARQP GSSIKPLVAYGPALDTGTYTLASAIDDAPYYYSGTDAKLVTNFTKGEYRGLITLRQALTISQNVPAVKILTKLTPQVGYN YLEKFGISTLVSPKNAINGAHDVVQSLALGGMTRGVSNIDMCAAYAAIANKGTYTKPVYYTKVLDSDGNIIIDNTIPETH KVLNENSDWLLIQGLRSVATDGTARSANFSSQPVAGKTGTTQYDSDRWFCGFTPYYTATIWVGYDDNSRELGNVVNHNII WRSIMQTIHENLNLPTGTYEQPSGIVEASVCSKSGLLPVEGLCDQDSEGNCIITEYFTEDTVPTEYCTTHTKVTFCNVSG DIATSGCPSTTTKIMRKKSSADKLGDDKEGSEFKTWDADISITDTELSKLCTLHSATTKPTKATNTNKSTEETSSATQSE TKTDKSTSSSSSSTRRP
Sequences:
>Translated_897_residues MNYGDKGIKQKKKLLNSATTKLGTKLGIFFIKLALVGIIALVVAGSCLVFGSFQGIIENAPDIASINVSPEGFATKIYDT DNNEIQTLSSAGANRTYVTIDQIPLNLQHAFIAIEDERFYEHNGIDMKGILRAASITLSSGHMSQGASTITQQLIKNNVF NAYNESDIEKIKRKVQEQYLAIKLETVMSKKSILENYLNTINLGNGYYGVQAAAKGYFNKDVSELSLSECAVIASITKSP TGLNPIRHADRNRDRQSQVLLNMKDQGYISQAEYDDALTDDVYARLEGIELAGTSTTTYSYFVDELINQLTSDLMSQKGY TESQATSLIYRGGLQVYSTQDTMMQQVADDVINDPDNYNDNTHFSINYALTVKQTDGTFSYYSHNSMANWYTKKLGDTSF SLTLTDEDAARAYVEAYKEELLKEGGEVYSETLTFTLQPQISFTIMDQTNGHVKVMVGGRGDKTLNRSLNRASNDIARQP GSSIKPLVAYGPALDTGTYTLASAIDDAPYYYSGTDAKLVTNFTKGEYRGLITLRQALTISQNVPAVKILTKLTPQVGYN YLEKFGISTLVSPKNAINGAHDVVQSLALGGMTRGVSNIDMCAAYAAIANKGTYTKPVYYTKVLDSDGNIIIDNTIPETH KVLNENSDWLLIQGLRSVATDGTARSANFSSQPVAGKTGTTQYDSDRWFCGFTPYYTATIWVGYDDNSRELGNVVNHNII WRSIMQTIHENLNLPTGTYEQPSGIVEASVCSKSGLLPVEGLCDQDSEGNCIITEYFTEDTVPTEYCTTHTKVTFCNVSG DIATSGCPSTTTKIMRKKSSADKLGDDKEGSEFKTWDADISITDTELSKLCTLHSATTKPTKATNTNKSTEETSSATQSE TKTDKSTSSSSSSTRRP >Mature_897_residues MNYGDKGIKQKKKLLNSATTKLGTKLGIFFIKLALVGIIALVVAGSCLVFGSFQGIIENAPDIASINVSPEGFATKIYDT DNNEIQTLSSAGANRTYVTIDQIPLNLQHAFIAIEDERFYEHNGIDMKGILRAASITLSSGHMSQGASTITQQLIKNNVF NAYNESDIEKIKRKVQEQYLAIKLETVMSKKSILENYLNTINLGNGYYGVQAAAKGYFNKDVSELSLSECAVIASITKSP TGLNPIRHADRNRDRQSQVLLNMKDQGYISQAEYDDALTDDVYARLEGIELAGTSTTTYSYFVDELINQLTSDLMSQKGY TESQATSLIYRGGLQVYSTQDTMMQQVADDVINDPDNYNDNTHFSINYALTVKQTDGTFSYYSHNSMANWYTKKLGDTSF SLTLTDEDAARAYVEAYKEELLKEGGEVYSETLTFTLQPQISFTIMDQTNGHVKVMVGGRGDKTLNRSLNRASNDIARQP GSSIKPLVAYGPALDTGTYTLASAIDDAPYYYSGTDAKLVTNFTKGEYRGLITLRQALTISQNVPAVKILTKLTPQVGYN YLEKFGISTLVSPKNAINGAHDVVQSLALGGMTRGVSNIDMCAAYAAIANKGTYTKPVYYTKVLDSDGNIIIDNTIPETH KVLNENSDWLLIQGLRSVATDGTARSANFSSQPVAGKTGTTQYDSDRWFCGFTPYYTATIWVGYDDNSRELGNVVNHNII WRSIMQTIHENLNLPTGTYEQPSGIVEASVCSKSGLLPVEGLCDQDSEGNCIITEYFTEDTVPTEYCTTHTKVTFCNVSG DIATSGCPSTTTKIMRKKSSADKLGDDKEGSEFKTWDADISITDTELSKLCTLHSATTKPTKATNTNKSTEETSSATQSE TKTDKSTSSSSSSTRRP
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG0744
COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)
Gene ontology:
Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=647, Percent_Identity=31.5301391035549, Blast_Score=251, Evalue=1e-67, Organism=Escherichia coli, GI1786343, Length=278, Percent_Identity=30.5755395683453, Blast_Score=101, Evalue=2e-22, Organism=Escherichia coli, GI1789601, Length=186, Percent_Identity=36.0215053763441, Blast_Score=100, Evalue=3e-22, Organism=Escherichia coli, GI1788867, Length=211, Percent_Identity=28.436018957346, Blast_Score=98, Evalue=2e-21,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.- [C]
Molecular weight: Translated: 98272; Mature: 98272
Theoretical pI: Translated: 5.09; Mature: 5.09
Prosite motif: PS00421 TM4_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNYGDKGIKQKKKLLNSATTKLGTKLGIFFIKLALVGIIALVVAGSCLVFGSFQGIIENA CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHCCC PDIASINVSPEGFATKIYDTDNNEIQTLSSAGANRTYVTIDQIPLNLQHAFIAIEDERFY CCEEEEECCCCCCEEEEEECCCCCCHHHHCCCCCCEEEEEECCCCCEEEEEEEEECCHHH EHNGIDMKGILRAASITLSSGHMSQGASTITQQLIKNNVFNAYNESDIEKIKRKVQEQYL HCCCCCHHHHHHHHEEEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH AIKLETVMSKKSILENYLNTINLGNGYYGVQAAAKGYFNKDVSELSLSECAVIASITKSP HHHHHHHHHHHHHHHHHHHHEECCCCEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC TGLNPIRHADRNRDRQSQVLLNMKDQGYISQAEYDDALTDDVYARLEGIELAGTSTTTYS CCCCHHHHHHCCCCCCHHEEEEECCCCCEECCCCCCHHHHHHHHHHCCEEEECCCCCHHH YFVDELINQLTSDLMSQKGYTESQATSLIYRGGLQVYSTQDTMMQQVADDVINDPDNYND HHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCEEEEECHHHHHHHHHHHHHCCCCCCCC NTHFSINYALTVKQTDGTFSYYSHNSMANWYTKKLGDTSFSLTLTDEDAARAYVEAYKEE CCEEEEEEEEEEEECCCCEEEECCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHH LLKEGGEVYSETLTFTLQPQISFTIMDQTNGHVKVMVGGRGDKTLNRSLNRASNDIARQP HHHCCCCEEEEEEEEEECCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCC GSSIKPLVAYGPALDTGTYTLASAIDDAPYYYSGTDAKLVTNFTKGEYRGLITLRQALTI CCCCCCCEEECCCCCCCCCHHHHHHCCCCCEECCCCCEEEEECCCCCHHHHHHHHHHHHH SQNVPAVKILTKLTPQVGYNYLEKFGISTLVSPKNAINGAHDVVQSLALGGMTRGVSNID CCCCCHHHHHHHHCHHHHHHHHHHCCCHHCCCCHHHCCHHHHHHHHHHHHHHHCCCCHHH MCAAYAAIANKGTYTKPVYYTKVLDSDGNIIIDNTIPETHKVLNENSDWLLIQGLRSVAT HHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEECCCCHHHHHHCCCCCEEEEECHHHHHC DGTARSANFSSQPVAGKTGTTQYDSDRWFCGFTPYYTATIWVGYDDNSRELGNVVNHNII CCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEEEECCCCHHHHHHHHHHHH WRSIMQTIHENLNLPTGTYEQPSGIVEASVCSKSGLLPVEGLCDQDSEGNCIITEYFTED HHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCC TVPTEYCTTHTKVTFCNVSGDIATSGCPSTTTKIMRKKSSADKLGDDKEGSEFKTWDADI CCCHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHHCCCCCCCCCEEEECCCE SITDTELSKLCTLHSATTKPTKATNTNKSTEETSSATQSETKTDKSTSSSSSSTRRP EEEHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC >Mature Secondary Structure MNYGDKGIKQKKKLLNSATTKLGTKLGIFFIKLALVGIIALVVAGSCLVFGSFQGIIENA CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHCCC PDIASINVSPEGFATKIYDTDNNEIQTLSSAGANRTYVTIDQIPLNLQHAFIAIEDERFY CCEEEEECCCCCCEEEEEECCCCCCHHHHCCCCCCEEEEEECCCCCEEEEEEEEECCHHH EHNGIDMKGILRAASITLSSGHMSQGASTITQQLIKNNVFNAYNESDIEKIKRKVQEQYL HCCCCCHHHHHHHHEEEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH AIKLETVMSKKSILENYLNTINLGNGYYGVQAAAKGYFNKDVSELSLSECAVIASITKSP HHHHHHHHHHHHHHHHHHHHEECCCCEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC TGLNPIRHADRNRDRQSQVLLNMKDQGYISQAEYDDALTDDVYARLEGIELAGTSTTTYS CCCCHHHHHHCCCCCCHHEEEEECCCCCEECCCCCCHHHHHHHHHHCCEEEECCCCCHHH YFVDELINQLTSDLMSQKGYTESQATSLIYRGGLQVYSTQDTMMQQVADDVINDPDNYND HHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCEEEEECHHHHHHHHHHHHHCCCCCCCC NTHFSINYALTVKQTDGTFSYYSHNSMANWYTKKLGDTSFSLTLTDEDAARAYVEAYKEE CCEEEEEEEEEEEECCCCEEEECCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHH LLKEGGEVYSETLTFTLQPQISFTIMDQTNGHVKVMVGGRGDKTLNRSLNRASNDIARQP HHHCCCCEEEEEEEEEECCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCC GSSIKPLVAYGPALDTGTYTLASAIDDAPYYYSGTDAKLVTNFTKGEYRGLITLRQALTI CCCCCCCEEECCCCCCCCCHHHHHHCCCCCEECCCCCEEEEECCCCCHHHHHHHHHHHHH SQNVPAVKILTKLTPQVGYNYLEKFGISTLVSPKNAINGAHDVVQSLALGGMTRGVSNID CCCCCHHHHHHHHCHHHHHHHHHHCCCHHCCCCHHHCCHHHHHHHHHHHHHHHCCCCHHH MCAAYAAIANKGTYTKPVYYTKVLDSDGNIIIDNTIPETHKVLNENSDWLLIQGLRSVAT HHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEECCCCHHHHHHCCCCCEEEEECHHHHHC DGTARSANFSSQPVAGKTGTTQYDSDRWFCGFTPYYTATIWVGYDDNSRELGNVVNHNII CCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEEEECCCCHHHHHHHHHHHH WRSIMQTIHENLNLPTGTYEQPSGIVEASVCSKSGLLPVEGLCDQDSEGNCIITEYFTED HHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCC TVPTEYCTTHTKVTFCNVSGDIATSGCPSTTTKIMRKKSSADKLGDDKEGSEFKTWDADI CCCHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHHCCCCCCCCCEEEECCCE SITDTELSKLCTLHSATTKPTKATNTNKSTEETSSATQSETKTDKSTSSSSSSTRRP EEEHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA