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The map label for this gene is nudE [C]

Identifier: 238917385

GI number: 238917385

Start: 1515495

End: 1516055

Strand: Reverse

Name: nudE [C]

Synonym: EUBELI_01462

Alternate gene names: 238917385

Gene position: 1516055-1515495 (Counterclockwise)

Preceding gene: 238917386

Following gene: 238917384

Centisome position: 70.71

GC content: 36.72

Gene sequence:

>561_bases
ATGAAATTCGATGGAATAAAAAAGGTTTCAGAGGGAAGATTCATAAACAGATACGATCTGTATTATACAACTGAGGATGA
TAAGAAAAAGGTTTACGAAATCATAAGCAGAAACAAGGATATAAAAACTATTGAAGATATAAGAAACGAAAAGACTGATG
GTGTGGTTATTGTTGCAACAGACGAATCGGACGAACATATTCTGATTAATAAGGAATATAGAATGTCTGTGGGAGATTAT
GTTTATAATTTTCCGGCAGGACTTATTGATGAAGGAGAAACTCCTGAGATGGCAGCAAAACGTGAGCTCAAAGAGGAGAC
AGGACTTGATCTTATTATAATTGAGGATAAACTCTATGACAGCTACAGTGCCATAGGATTTTCTAATGAGACAAATGCCG
TGGTTATAGGAAAAGCTACAGGAGAATTTTCACCCAGTACATCTACATTTGAGGAAATTGCAGCAGCATGGTATTCGAAG
GAAGAAGTAAAGGCACTTCTTAAAGACAGTCATTTTGCAGCGAGAACACAGGCGTTCTGCTATATGTGGGCAAGAAATTA
A

Upstream 100 bases:

>100_bases
CATGAAATACGGTATTGCAATGAGAAACTCGACTAATGGATGGATGATGGATGTTGTTCATGAAGCGGTTGGCAGAATGA
AGGGAAAGAAGGACAGGTAA

Downstream 100 bases:

>100_bases
TAATAAAGAGGCAATGGTATGATGAAAGGTAAAAGAATAATAACAGGTATTATGCTGGTACTGGTGATGGTCTGTATATC
AGGATGTAAAAAGATATCAA

Product: ADP-ribose pyrophosphatase

Products: AMP; D-Ribose 5- Phosphate. [C]

Alternate protein names: MutT/NUDIX Family Hydrolase; Nucleotide Diphosphate NUDIX Family Hydrolase; Nudix-Family Hydrolase; Zn-Finger Containing NTP Pyrophosphohydrolase; Nudix Family Hydrolase; ADP-Ribose Pyrophosphatase; NUDIX Domain-Containing Protein; NUDIX Hydrolase; Nucleotide Diphosphate Hydrolase

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MKFDGIKKVSEGRFINRYDLYYTTEDDKKKVYEIISRNKDIKTIEDIRNEKTDGVVIVATDESDEHILINKEYRMSVGDY
VYNFPAGLIDEGETPEMAAKRELKEETGLDLIIIEDKLYDSYSAIGFSNETNAVVIGKATGEFSPSTSTFEEIAAAWYSK
EEVKALLKDSHFAARTQAFCYMWARN

Sequences:

>Translated_186_residues
MKFDGIKKVSEGRFINRYDLYYTTEDDKKKVYEIISRNKDIKTIEDIRNEKTDGVVIVATDESDEHILINKEYRMSVGDY
VYNFPAGLIDEGETPEMAAKRELKEETGLDLIIIEDKLYDSYSAIGFSNETNAVVIGKATGEFSPSTSTFEEIAAAWYSK
EEVKALLKDSHFAARTQAFCYMWARN
>Mature_186_residues
MKFDGIKKVSEGRFINRYDLYYTTEDDKKKVYEIISRNKDIKTIEDIRNEKTDGVVIVATDESDEHILINKEYRMSVGDY
VYNFPAGLIDEGETPEMAAKRELKEETGLDLIIIEDKLYDSYSAIGFSNETNAVVIGKATGEFSPSTSTFEEIAAAWYSK
EEVKALLKDSHFAARTQAFCYMWARN

Specific function: Active On Adenosine(5')Triphospho(5')Adenosine (Ap3a), ADP-Ribose, NADH, Adenosine(5')Diphospho(5')Adenosine (Ap2a). [C]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI37594464, Length=104, Percent_Identity=38.4615384615385, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 21292; Mature: 21292

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFDGIKKVSEGRFINRYDLYYTTEDDKKKVYEIISRNKDIKTIEDIRNEKTDGVVIVAT
CCCCCCCHHCCCCEEEEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEEEEE
DESDEHILINKEYRMSVGDYVYNFPAGLIDEGETPEMAAKRELKEETGLDLIIIEDKLYD
CCCCCEEEEECHHHCCHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCC
SYSAIGFSNETNAVVIGKATGEFSPSTSTFEEIAAAWYSKEEVKALLKDSHFAARTQAFC
CHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHEEEE
YMWARN
EEEECC
>Mature Secondary Structure
MKFDGIKKVSEGRFINRYDLYYTTEDDKKKVYEIISRNKDIKTIEDIRNEKTDGVVIVAT
CCCCCCCHHCCCCEEEEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEEEEE
DESDEHILINKEYRMSVGDYVYNFPAGLIDEGETPEMAAKRELKEETGLDLIIIEDKLYD
CCCCCEEEEECHHHCCHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCC
SYSAIGFSNETNAVVIGKATGEFSPSTSTFEEIAAAWYSKEEVKALLKDSHFAARTQAFC
CHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHEEEE
YMWARN
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ADP-Ribose; H2O [C]

Specific reaction: ADP-Ribose + H2O = AMP + D-Ribose 5- Phosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA