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The map label for this gene is yajL [H]

Identifier: 238917381

GI number: 238917381

Start: 1512100

End: 1512648

Strand: Reverse

Name: yajL [H]

Synonym: EUBELI_01458

Alternate gene names: 238917381

Gene position: 1512648-1512100 (Counterclockwise)

Preceding gene: 238917383

Following gene: 238917380

Centisome position: 70.55

GC content: 38.07

Gene sequence:

>549_bases
ATGAAGGTATGTGCATTTCTTACAGATGGTTTTGAAACGGTAGAAGCACTTGCAGTTGTAGATATATTAAGAAGAGCGGA
TATTAAGACAGATGTGATATCAATAACAGGTGACATTAATGTAAAAAGTGCTCAGGGGGTAATTGTTCAGGCTGATGAGC
TTTTGGATGAATATGTATTTGAAGGAGATGAACTATTATTCCTTCCGGGTGGTCCGGGTCATAAGTCATATTATGATTGC
AAGGATTTACTGGAACTTCTTAAAGAATACAATAAGAAGAATAACAGAATTGCAGCCATATGTGCAGCACCTTCGGTTCT
GGGAAATCTCGGACTTCTTGATGGAAAGAAAGCAATGGCATTTCCTGGATTTGAAGATCAGTTAAATGGTGCAACTGTAG
TTACAGCTCCTGAGCGCGTTGTTACAGATGGTAATATTACAACATCAAGAGGAATGGGAACATCTATTGATTTGGGACTC
GAACTTGTAAGACTTATCAAAGGGGAAGAACTGGCAGAAAAATTAAAAGCTTCTACCCAGTATATTTAG

Upstream 100 bases:

>100_bases
ACATTAATATTAATATTTTGTAAAATATAAGTTTGTAAAAATAAAAAAATGTTGTATAATCAACTCGTATGTATATTTTT
TCGAGCGGAGGAAATAATTG

Downstream 100 bases:

>100_bases
TATGAGGGAGAGAAATTACGATGGGATTCGATAATTATGATGAAGAAAAAATACGCCGCAACAGAAAAAGAAAAATGCTG
TTGATGAAGAAGAAAAGACA

Product: 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKVCAFLTDGFETVEALAVVDILRRADIKTDVISITGDINVKSAQGVIVQADELLDEYVFEGDELLFLPGGPGHKSYYDC
KDLLELLKEYNKKNNRIAAICAAPSVLGNLGLLDGKKAMAFPGFEDQLNGATVVTAPERVVTDGNITTSRGMGTSIDLGL
ELVRLIKGEELAEKLKASTQYI

Sequences:

>Translated_182_residues
MKVCAFLTDGFETVEALAVVDILRRADIKTDVISITGDINVKSAQGVIVQADELLDEYVFEGDELLFLPGGPGHKSYYDC
KDLLELLKEYNKKNNRIAAICAAPSVLGNLGLLDGKKAMAFPGFEDQLNGATVVTAPERVVTDGNITTSRGMGTSIDLGL
ELVRLIKGEELAEKLKASTQYI
>Mature_182_residues
MKVCAFLTDGFETVEALAVVDILRRADIKTDVISITGDINVKSAQGVIVQADELLDEYVFEGDELLFLPGGPGHKSYYDC
KDLLELLKEYNKKNNRIAAICAAPSVLGNLGLLDGKKAMAFPGFEDQLNGATVVTAPERVVTDGNITTSRGMGTSIDLGL
ELVRLIKGEELAEKLKASTQYI

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=175, Percent_Identity=34.8571428571429, Blast_Score=91, Evalue=5e-19,
Organism=Homo sapiens, GI31543380, Length=175, Percent_Identity=34.8571428571429, Blast_Score=91, Evalue=5e-19,
Organism=Escherichia coli, GI87081736, Length=181, Percent_Identity=32.5966850828729, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531319, Length=171, Percent_Identity=30.4093567251462, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24653499, Length=178, Percent_Identity=33.1460674157303, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28571932, Length=170, Percent_Identity=32.9411764705882, Blast_Score=88, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 19653; Mature: 19653

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVCAFLTDGFETVEALAVVDILRRADIKTDVISITGDINVKSAQGVIVQADELLDEYVF
CCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEECCCCEEEEHHHHHHHHHH
EGDELLFLPGGPGHKSYYDCKDLLELLKEYNKKNNRIAAICAAPSVLGNLGLLDGKKAMA
CCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECHHHHHCCCCCCCCCCEE
FPGFEDQLNGATVVTAPERVVTDGNITTSRGMGTSIDLGLELVRLIKGEELAEKLKASTQ
CCCCHHHCCCCEEEECCCEEEECCCEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCC
YI
CC
>Mature Secondary Structure
MKVCAFLTDGFETVEALAVVDILRRADIKTDVISITGDINVKSAQGVIVQADELLDEYVF
CCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEECCCCEEEEHHHHHHHHHH
EGDELLFLPGGPGHKSYYDCKDLLELLKEYNKKNNRIAAICAAPSVLGNLGLLDGKKAMA
CCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECHHHHHCCCCCCCCCCEE
FPGFEDQLNGATVVTAPERVVTDGNITTSRGMGTSIDLGLELVRLIKGEELAEKLKASTQ
CCCCHHHCCCCEEEECCCEEEECCCEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCC
YI
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]