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The map label for this gene is ilvC [H]

Identifier: 238917298

GI number: 238917298

Start: 1414233

End: 1415258

Strand: Reverse

Name: ilvC [H]

Synonym: EUBELI_01373

Alternate gene names: 238917298

Gene position: 1415258-1414233 (Counterclockwise)

Preceding gene: 238917299

Following gene: 238917296

Centisome position: 66.0

GC content: 42.2

Gene sequence:

>1026_bases
ATGGCAGAAGCTAAGATCTATTATCAGTCAGATTGTAATTTATCATTACTTGACGGTAAGACAATCGCTATTATCGGTTA
TGGTAGCCAGGGACATGCACACGCATTAAATCTTAAGGATTCAGGTTGTCATGTAATTATCGGACTTTATGAGGGCTCTA
AGTCATGGAAGAGAGCTGAAGAGCAGGGATTTGAAGTATTCACTGCTGCAGAGGCTGCTAAGAGAGCTGATATCATCATG
ATTCTTATCAATGATGAGAAGCAGGCTAAGCTTTATAAGGAAGATATCGAGCCAAATCTTGAGCCGGGTAACATGCTTAT
GTTCGCACATGGTTTCAACATTCACTTTGGTTTAATTAAGGCTCCTAAGGGTGTTGATGTAACAATGATCGCACCTAAGG
CACCTGGACATACAGTTCGTTCAGAATATCAGGCTGGAAAGGGTACTCCTTGTCTTGTAGCTGTAGAGCAGGATGAGACA
GGTAAGGCTCTTGATATGGCACTTGCTTATGGTCTTGGTATTGGTGGAGCAAGAGCCGGTCTTCTTGAGACTACATTCAG
AACAGAGACAGAGACAGACCTCTTCGGTGAGCAGGCAGTTCTTTGCGGTGGTGTTTGTGCACTTATGCAGGCTGGTTTCG
AAACTCTTTGCGAAGCTGGATATGATCCACGTAACGCTTACTTCGAGTGTATCCACGAGATGAAGCTTATTGTTGACCTT
ATTTACCAGTCAGGTTTTGCAGGAATGAGATATTCAATCTCTAACACAGCTGAGTATGGTGATTACATAACAGGACCTAA
GATTATCACAGAGGATACTAAGAAGGCTATGAAGAAGATTCTTTCTGATATTCAGGATGGTACATTTGCTAAGGAATTCT
TACTTGACATGAGCGATGCTGGTGGACAGGTACATTTCAAGGCTATGAGAAAGCTTGCTTCTGAGCATCCATCTGAGAAG
GTTGGAGCTGAGATTAGAAAGCTTTACAGCTGGAACAATGAAAAGGATATGCTTATCAACAACTAA

Upstream 100 bases:

>100_bases
TTGCAAGAGGGAGTGCTGATTTGAAAAAGAGGTAATAATTCTTTGGAGTATCCAGAGAACTTTTACAATATAAAACACAT
TTATATGGAGGTAGTTTAAA

Downstream 100 bases:

>100_bases
TAATCAGTAATTGATAATATTTAAGGGCTGCCGTTATGGCAGCCCTTTTTGAATGTAATGATGAGTCAGAGAAAATCATT
TATTCCTGATCTTTTTTGAA

Product: ketol-acid reductoisomerase

Products: NA

Alternate protein names: Acetohydroxy-acid isomeroreductase; Alpha-keto-beta-hydroxylacil reductoisomerase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MAEAKIYYQSDCNLSLLDGKTIAIIGYGSQGHAHALNLKDSGCHVIIGLYEGSKSWKRAEEQGFEVFTAAEAAKRADIIM
ILINDEKQAKLYKEDIEPNLEPGNMLMFAHGFNIHFGLIKAPKGVDVTMIAPKAPGHTVRSEYQAGKGTPCLVAVEQDET
GKALDMALAYGLGIGGARAGLLETTFRTETETDLFGEQAVLCGGVCALMQAGFETLCEAGYDPRNAYFECIHEMKLIVDL
IYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKKAMKKILSDIQDGTFAKEFLLDMSDAGGQVHFKAMRKLASEHPSEK
VGAEIRKLYSWNNEKDMLINN

Sequences:

>Translated_341_residues
MAEAKIYYQSDCNLSLLDGKTIAIIGYGSQGHAHALNLKDSGCHVIIGLYEGSKSWKRAEEQGFEVFTAAEAAKRADIIM
ILINDEKQAKLYKEDIEPNLEPGNMLMFAHGFNIHFGLIKAPKGVDVTMIAPKAPGHTVRSEYQAGKGTPCLVAVEQDET
GKALDMALAYGLGIGGARAGLLETTFRTETETDLFGEQAVLCGGVCALMQAGFETLCEAGYDPRNAYFECIHEMKLIVDL
IYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKKAMKKILSDIQDGTFAKEFLLDMSDAGGQVHFKAMRKLASEHPSEK
VGAEIRKLYSWNNEKDMLINN
>Mature_340_residues
AEAKIYYQSDCNLSLLDGKTIAIIGYGSQGHAHALNLKDSGCHVIIGLYEGSKSWKRAEEQGFEVFTAAEAAKRADIIMI
LINDEKQAKLYKEDIEPNLEPGNMLMFAHGFNIHFGLIKAPKGVDVTMIAPKAPGHTVRSEYQAGKGTPCLVAVEQDETG
KALDMALAYGLGIGGARAGLLETTFRTETETDLFGEQAVLCGGVCALMQAGFETLCEAGYDPRNAYFECIHEMKLIVDLI
YQSGFAGMRYSISNTAEYGDYITGPKIITEDTKKAMKKILSDIQDGTFAKEFLLDMSDAGGQVHFKAMRKLASEHPSEKV
GAEIRKLYSWNNEKDMLINN

Specific function: Valine and isoleucine biosynthesis; second step. [C]

COG id: COG0059

COG function: function code EH; Ketol-acid reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketol-acid reductoisomerase family [H]

Homologues:

Organism=Escherichia coli, GI1790210, Length=302, Percent_Identity=35.0993377483444, Blast_Score=154, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6323387, Length=327, Percent_Identity=34.5565749235474, Blast_Score=146, Evalue=4e-36,

Paralogues:

None

Copy number: 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013023
- InterPro:   IPR000506
- InterPro:   IPR013328
- InterPro:   IPR013116 [H]

Pfam domain/function: PF01450 IlvC; PF07991 IlvN [H]

EC number: =1.1.1.86 [H]

Molecular weight: Translated: 37380; Mature: 37249

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEAKIYYQSDCNLSLLDGKTIAIIGYGSQGHAHALNLKDSGCHVIIGLYEGSKSWKRAE
CCCCEEEEECCCCEEEECCCEEEEEEECCCCCEEEEEECCCCCEEEEEEEECCCHHHHHH
EQGFEVFTAAEAAKRADIIMILINDEKQAKLYKEDIEPNLEPGNMLMFAHGFNIHFGLIK
HCCCEEEEHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCEEEEEECCEEEEEEEE
APKGVDVTMIAPKAPGHTVRSEYQAGKGTPCLVAVEQDETGKALDMALAYGLGIGGARAG
CCCCCEEEEECCCCCCCHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCHHCC
LLETTFRTETETDLFGEQAVLCGGVCALMQAGFETLCEAGYDPRNAYFECIHEMKLIVDL
HHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKKAMKKILSDIQDGTFAKEFLLDMSDA
HHHCCCCCEEEEECCCHHCCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
GGQVHFKAMRKLASEHPSEKVGAEIRKLYSWNNEKDMLINN
CCEEHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECC
>Mature Secondary Structure 
AEAKIYYQSDCNLSLLDGKTIAIIGYGSQGHAHALNLKDSGCHVIIGLYEGSKSWKRAE
CCCEEEEECCCCEEEECCCEEEEEEECCCCCEEEEEECCCCCEEEEEEEECCCHHHHHH
EQGFEVFTAAEAAKRADIIMILINDEKQAKLYKEDIEPNLEPGNMLMFAHGFNIHFGLIK
HCCCEEEEHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCEEEEEECCEEEEEEEE
APKGVDVTMIAPKAPGHTVRSEYQAGKGTPCLVAVEQDETGKALDMALAYGLGIGGARAG
CCCCCEEEEECCCCCCCHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCHHCC
LLETTFRTETETDLFGEQAVLCGGVCALMQAGFETLCEAGYDPRNAYFECIHEMKLIVDL
HHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKKAMKKILSDIQDGTFAKEFLLDMSDA
HHHCCCCCEEEEECCCHHCCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
GGQVHFKAMRKLASEHPSEKVGAEIRKLYSWNNEKDMLINN
CCEEHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA