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The map label for this gene is ilvH [H]

Identifier: 238917299

GI number: 238917299

Start: 1415324

End: 1415821

Strand: Reverse

Name: ilvH [H]

Synonym: EUBELI_01374

Alternate gene names: 238917299

Gene position: 1415821-1415324 (Counterclockwise)

Preceding gene: 238917301

Following gene: 238917298

Centisome position: 66.03

GC content: 39.76

Gene sequence:

>498_bases
ATGAGACGAGCAGTTTTTTCTATTCTCGTAGGTAATTCAGCCGGTGTACTTAGCCGTGTTGCTGGTATGTTCAGCCGCAG
AGGATATAATATAGACAGCCTTACTGTTGGTGAGACTCTCAACCCTGAGTATTCACGAATGACTATCGCAGTAACAGGTG
AGGATGATGTTCTTGAGCAGATTGAGAAACAGCTTAACAAACTCATTGATGTGAAGGAAATTGTAGAACTTCCTGCACAT
GAGTCTGTTTGCAGGGAACTTGTTATGATTAAGGTTGAATGTGGTCCGGAGAAGAGACAGCAGGTTTCATCTATAGCAGA
TATATTCAGAGCCAATATTGTTGATGTATCAAAAGAGTCAATGATAATTGCACTTACAGGAAGTTTGAGTAAGATGAATG
CATTTATTGAACTTCTTGAAGACTTCAATATTACAGAGGTTGCAAGAACAGGTATTACAGGTCTTGCAAGAGGGAGTGCT
GATTTGAAAAAGAGGTAA

Upstream 100 bases:

>100_bases
ATGCTATAAGTGGGCGATTGACAGATTGATGTTGTGTGCTATAATTAATTGGCAATTAAAAGTAATTTGCAGATGAATTA
GAGTTTTAGGAGTGTTAGAT

Downstream 100 bases:

>100_bases
TAATTCTTTGGAGTATCCAGAGAACTTTTACAATATAAAACACATTTATATGGAGGTAGTTTAAAATGGCAGAAGCTAAG
ATCTATTATCAGTCAGATTG

Product: acetolactate synthase

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MRRAVFSILVGNSAGVLSRVAGMFSRRGYNIDSLTVGETLNPEYSRMTIAVTGEDDVLEQIEKQLNKLIDVKEIVELPAH
ESVCRELVMIKVECGPEKRQQVSSIADIFRANIVDVSKESMIIALTGSLSKMNAFIELLEDFNITEVARTGITGLARGSA
DLKKR

Sequences:

>Translated_165_residues
MRRAVFSILVGNSAGVLSRVAGMFSRRGYNIDSLTVGETLNPEYSRMTIAVTGEDDVLEQIEKQLNKLIDVKEIVELPAH
ESVCRELVMIKVECGPEKRQQVSSIADIFRANIVDVSKESMIIALTGSLSKMNAFIELLEDFNITEVARTGITGLARGSA
DLKKR
>Mature_165_residues
MRRAVFSILVGNSAGVLSRVAGMFSRRGYNIDSLTVGETLNPEYSRMTIAVTGEDDVLEQIEKQLNKLIDVKEIVELPAH
ESVCRELVMIKVECGPEKRQQVSSIADIFRANIVDVSKESMIIALTGSLSKMNAFIELLEDFNITEVARTGITGLARGSA
DLKKR

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=159, Percent_Identity=46.5408805031447, Blast_Score=142, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6319837, Length=205, Percent_Identity=29.7560975609756, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 18188; Mature: 18188

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAVFSILVGNSAGVLSRVAGMFSRRGYNIDSLTVGETLNPEYSRMTIAVTGEDDVLEQ
CCHHHEEEEECCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEEEEECCHHHHHH
IEKQLNKLIDVKEIVELPAHESVCRELVMIKVECGPEKRQQVSSIADIFRANIVDVSKES
HHHHHHHHHCHHHHHHCCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCC
MIIALTGSLSKMNAFIELLEDFNITEVARTGITGLARGSADLKKR
EEEEEECCHHHHHHHHHHHHCCCHHHHHHHCCHHHCCCCCCCCCC
>Mature Secondary Structure
MRRAVFSILVGNSAGVLSRVAGMFSRRGYNIDSLTVGETLNPEYSRMTIAVTGEDDVLEQ
CCHHHEEEEECCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEEEEECCHHHHHH
IEKQLNKLIDVKEIVELPAHESVCRELVMIKVECGPEKRQQVSSIADIFRANIVDVSKES
HHHHHHHHHCHHHHHHCCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCC
MIIALTGSLSKMNAFIELLEDFNITEVARTGITGLARGSADLKKR
EEEEEECCHHHHHHHHHHHHCCCHHHHHHHCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]