| Definition | Eubacterium eligens ATCC 27750 chromosome, complete genome. |
|---|---|
| Accession | NC_012778 |
| Length | 2,144,190 |
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The map label for this gene is comEC [H]
Identifier: 238917139
GI number: 238917139
Start: 1222459
End: 1224879
Strand: Reverse
Name: comEC [H]
Synonym: EUBELI_01211
Alternate gene names: 238917139
Gene position: 1224879-1222459 (Counterclockwise)
Preceding gene: 238917140
Following gene: 238917138
Centisome position: 57.13
GC content: 36.14
Gene sequence:
>2421_bases TTGAAAAGACCTTTTTTTGTTGCAGCAGTTATCGGACTGGCTGCTGCGTATTTGTCAATATATTCATCTGGATATATTGT ATTGTCAGCAGGCGTTATAATTATTGCTTGCTATTTTATATTCTATAAATACAGTAAAACACCATTGTTTTACATTCTGT TTGTTTTGATTTTTCCAATTATGGTAATAAGAACTGAATATTACAGCAGGGGGATGCGTTATCAGGGAAAGCTGACGCAG GACTGTTACGCATATATAAAAGGCGAAGCAGTGTCTGTAATAAAAGGTGGTAACAGTTATGCAACAAGGCTTAATAATGC ATTGCTCATTCCTGACTGGAAAAATAATGATGAAAAGGTTAATGAATCGGTAAAATCTGGAATTATTATATATTCGGAAG ATTCATTCTGTCATGCTGGTGATTATATCTGGGTGAGAGTAAAACTAAAGGATTTTGAAGAACCAACAAATGAAGGCCAG TTTAATGCAAGAGCTTATTATACATCAGATGGTATTAATTATCAGGGGATTTTTAATAAAACTGTTAATATAACACCATG CGAAGGAACTTTAAAAGCAAGCCTGTTAAATATAGCTGATTCAATAAAAAATGTATATGTTAATACATTTACACAAAAGA ATGCAGGTACCATGAGGGCGATTGTGCTTGGGGACAGGAGTGTTCTGGATGATGAGATTAAGGAGTTATACAAGAAAAAC GGAATATCACATATTCTTGCAATCAGTGCACTTCATATAACGATGGTTGGTATGCTGGTATACAGGATGCTGAAAAAAAT TATAAGCGTAATACAGGCGGCAGTGTTAAGCAGCGTTATAATGCTTTTCTATCTGTATATTACAGGAAACAGCGTGTCTG CCGGGCGTGCTGTCATTATGATTCTTGTTTTTATGCTTGCAGATGTGCTTGGCAGAACAAGTGATGGTGCTAATACGCTT GGATTGGCGGTTGTAATACTAATTATCAGAAATCCTTATTGTATAAGTAACGCAGGTTTTTTAATGTCATTTCTTGCTAT GGCAGGAATTATATTTGTAAAGCCGATTTTTTCTAATGAAGAAACAATTATGCTTTTTTTCAGAAAAAAGAAAATGGTAT CCATTACAGAAATGTTTATATACCACAATATCATAGATATGCTGATTACAGGCTTGTGTGTTCAGATTGCAACGCTTCCT GTTGTTTTAAGCATGTCAGGACAGATTGCCATTATAAGTCTTTTGCTTAATATAGTAGTTATACCGTTGATGTCAGTTAT TATGGTAAGTGGGATATTAACAGGAATTATGGGACTTATATCAATGAAAGCTGCGATATGGACTGCAGGTGCCGGAGAGT ACATTCTTGACTTATATAGCTGGTTGTGTGAAAAGGCATCAGGTTCATCAGGTGCAGTTATAGTAACAGGTCATCCTCCG GAAAAAGCGGTTGTTTTGTATTATGTGTTTCTTATTGTATGGTGTGTGATTTATTATATGAAAGTATTTTCCGGTATTTC AGGGAAATATAGAAATGTACTGCCTGCAATATTGTATTTGATTATTACTATACAGTTAAGATATAATACAGGCTGTTCAA TGAAGATAAGTATGCTTGATGTGGGACAGGGAGATTCAATAGTTTTGCAGACAAGTGATGGCTTCAATGCTTTATTTGAT GGAGGGAGTACAAGCAAGAAGAATATTGGACGGTACAGGATATATACTTATCTGAAATATGCCGGGGTACGGAGTCTTGA TTATGTATTTGTGAGTCATCCCGATAAGGATCACATAAGTGGAATATACGAACTTATTGATATGTGTGATAATACATTTG AAATAAAAAACATTGTTCTGCCGCATATTAACGATACGGATGAAACATTATTGGAAATCAGGAAAATGGCTGACAGAGTA GGAATAAATGTTTTATACGCGTGCAGGGGAGATGCTTTATCAGCAGGTAATCTTAGTATAAGCTGTGTACATCCATGTAA GAACTACAATTATGAATCAGCTAATGACTATTCAGCAGTCTATCTTATATCATTTGGAAAATTTTCCATGCTTATGACAG GAGATGCAGAGAGTAAAGCAGAGAAATGTCTGATACAGGATGCCAGAAAGTCAGACAGTGTGGTGGATTTGCAGAAGCTG TCTGGCATAAATGTATTAAAAGCTGGGCATCATGGCAGCAGAGGTGCAAGTTCAGAGAATTTTTTAAGGTTTGTTAAGCC TGAAACTGCACTGATATCCTGTGGAGTGGATAATTCATATGGACATCCGCATAATGAGACTTTGCAGAGATTAAAAGAGG CAGGTACGAAGGTGTACAGGACTGATGACAGAGGAGAGATTATGGTGCGGGTATGGGAAGATTCATATGCGATTGAAGTG TTTGGTGAGCAAAAAGAATAG
Upstream 100 bases:
>100_bases TATGTATCGTGATGTTATAAGTCTTGATGGTATTTTTTACATGAATAATGAAATTGTTGAAAAATAATTATATCTACGGT TATTTCCAGAAAGGAAATAC
Downstream 100 bases:
>100_bases AAGATGCATAGCATGCTATGATAAAATATTTTCAACTTGAACCACTTGTACATATCTGATACTATTGTTTAAGATTAGAA ACGGAGGCAGCAGGTTTGAA
Product: competence protein ComEC
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 806; Mature: 806
Protein sequence:
>806_residues MKRPFFVAAVIGLAAAYLSIYSSGYIVLSAGVIIIACYFIFYKYSKTPLFYILFVLIFPIMVIRTEYYSRGMRYQGKLTQ DCYAYIKGEAVSVIKGGNSYATRLNNALLIPDWKNNDEKVNESVKSGIIIYSEDSFCHAGDYIWVRVKLKDFEEPTNEGQ FNARAYYTSDGINYQGIFNKTVNITPCEGTLKASLLNIADSIKNVYVNTFTQKNAGTMRAIVLGDRSVLDDEIKELYKKN GISHILAISALHITMVGMLVYRMLKKIISVIQAAVLSSVIMLFYLYITGNSVSAGRAVIMILVFMLADVLGRTSDGANTL GLAVVILIIRNPYCISNAGFLMSFLAMAGIIFVKPIFSNEETIMLFFRKKKMVSITEMFIYHNIIDMLITGLCVQIATLP VVLSMSGQIAIISLLLNIVVIPLMSVIMVSGILTGIMGLISMKAAIWTAGAGEYILDLYSWLCEKASGSSGAVIVTGHPP EKAVVLYYVFLIVWCVIYYMKVFSGISGKYRNVLPAILYLIITIQLRYNTGCSMKISMLDVGQGDSIVLQTSDGFNALFD GGSTSKKNIGRYRIYTYLKYAGVRSLDYVFVSHPDKDHISGIYELIDMCDNTFEIKNIVLPHINDTDETLLEIRKMADRV GINVLYACRGDALSAGNLSISCVHPCKNYNYESANDYSAVYLISFGKFSMLMTGDAESKAEKCLIQDARKSDSVVDLQKL SGINVLKAGHHGSRGASSENFLRFVKPETALISCGVDNSYGHPHNETLQRLKEAGTKVYRTDDRGEIMVRVWEDSYAIEV FGEQKE
Sequences:
>Translated_806_residues MKRPFFVAAVIGLAAAYLSIYSSGYIVLSAGVIIIACYFIFYKYSKTPLFYILFVLIFPIMVIRTEYYSRGMRYQGKLTQ DCYAYIKGEAVSVIKGGNSYATRLNNALLIPDWKNNDEKVNESVKSGIIIYSEDSFCHAGDYIWVRVKLKDFEEPTNEGQ FNARAYYTSDGINYQGIFNKTVNITPCEGTLKASLLNIADSIKNVYVNTFTQKNAGTMRAIVLGDRSVLDDEIKELYKKN GISHILAISALHITMVGMLVYRMLKKIISVIQAAVLSSVIMLFYLYITGNSVSAGRAVIMILVFMLADVLGRTSDGANTL GLAVVILIIRNPYCISNAGFLMSFLAMAGIIFVKPIFSNEETIMLFFRKKKMVSITEMFIYHNIIDMLITGLCVQIATLP VVLSMSGQIAIISLLLNIVVIPLMSVIMVSGILTGIMGLISMKAAIWTAGAGEYILDLYSWLCEKASGSSGAVIVTGHPP EKAVVLYYVFLIVWCVIYYMKVFSGISGKYRNVLPAILYLIITIQLRYNTGCSMKISMLDVGQGDSIVLQTSDGFNALFD GGSTSKKNIGRYRIYTYLKYAGVRSLDYVFVSHPDKDHISGIYELIDMCDNTFEIKNIVLPHINDTDETLLEIRKMADRV GINVLYACRGDALSAGNLSISCVHPCKNYNYESANDYSAVYLISFGKFSMLMTGDAESKAEKCLIQDARKSDSVVDLQKL SGINVLKAGHHGSRGASSENFLRFVKPETALISCGVDNSYGHPHNETLQRLKEAGTKVYRTDDRGEIMVRVWEDSYAIEV FGEQKE >Mature_806_residues MKRPFFVAAVIGLAAAYLSIYSSGYIVLSAGVIIIACYFIFYKYSKTPLFYILFVLIFPIMVIRTEYYSRGMRYQGKLTQ DCYAYIKGEAVSVIKGGNSYATRLNNALLIPDWKNNDEKVNESVKSGIIIYSEDSFCHAGDYIWVRVKLKDFEEPTNEGQ FNARAYYTSDGINYQGIFNKTVNITPCEGTLKASLLNIADSIKNVYVNTFTQKNAGTMRAIVLGDRSVLDDEIKELYKKN GISHILAISALHITMVGMLVYRMLKKIISVIQAAVLSSVIMLFYLYITGNSVSAGRAVIMILVFMLADVLGRTSDGANTL GLAVVILIIRNPYCISNAGFLMSFLAMAGIIFVKPIFSNEETIMLFFRKKKMVSITEMFIYHNIIDMLITGLCVQIATLP VVLSMSGQIAIISLLLNIVVIPLMSVIMVSGILTGIMGLISMKAAIWTAGAGEYILDLYSWLCEKASGSSGAVIVTGHPP EKAVVLYYVFLIVWCVIYYMKVFSGISGKYRNVLPAILYLIITIQLRYNTGCSMKISMLDVGQGDSIVLQTSDGFNALFD GGSTSKKNIGRYRIYTYLKYAGVRSLDYVFVSHPDKDHISGIYELIDMCDNTFEIKNIVLPHINDTDETLLEIRKMADRV GINVLYACRGDALSAGNLSISCVHPCKNYNYESANDYSAVYLISFGKFSMLMTGDAESKAEKCLIQDARKSDSVVDLQKL SGINVLKAGHHGSRGASSENFLRFVKPETALISCGVDNSYGHPHNETLQRLKEAGTKVYRTDDRGEIMVRVWEDSYAIEV FGEQKE
Specific function: The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding [H]
COG id: COG2333
COG function: function code R; Predicted hydrolase (metallo-beta-lactamase superfamily)
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: To H.influenzae REC2, N.gonorrhoeae ComA and E.coli YcaI [H]
Homologues:
Organism=Escherichia coli, GI87081801, Length=711, Percent_Identity=21.9409282700422, Blast_Score=112, Evalue=9e-26,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001279 - InterPro: IPR004477 - InterPro: IPR004797 [H]
Pfam domain/function: PF03772 Competence; PF00753 Lactamase_B [H]
EC number: NA
Molecular weight: Translated: 89572; Mature: 89572
Theoretical pI: Translated: 8.22; Mature: 8.22
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.9 %Cys (Translated Protein) 3.6 %Met (Translated Protein) 5.5 %Cys+Met (Translated Protein) 1.9 %Cys (Mature Protein) 3.6 %Met (Mature Protein) 5.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKRPFFVAAVIGLAAAYLSIYSSGYIVLSAGVIIIACYFIFYKYSKTPLFYILFVLIFPI CCCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH MVIRTEYYSRGMRYQGKLTQDCYAYIKGEAVSVIKGGNSYATRLNNALLIPDWKNNDEKV HHHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEEECCCHHHHHCCCEEEECCCCCCHHHH NESVKSGIIIYSEDSFCHAGDYIWVRVKLKDFEEPTNEGQFNARAYYTSDGINYQGIFNK HHHHHCCEEEEECCCCEECCCEEEEEEEEECCCCCCCCCCCEEEEEEECCCCEECEEECC TVNITPCEGTLKASLLNIADSIKNVYVNTFTQKNAGTMRAIVLGDRSVLDDEIKELYKKN CEEEECCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHC GISHILAISALHITMVGMLVYRMLKKIISVIQAAVLSSVIMLFYLYITGNSVSAGRAVIM CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHH ILVFMLADVLGRTSDGANTLGLAVVILIIRNPYCISNAGFLMSFLAMAGIIFVKPIFSNE HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHEEEEECCCC ETIMLFFRKKKMVSITEMFIYHNIIDMLITGLCVQIATLPVVLSMSGQIAIISLLLNIVV CEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHH IPLMSVIMVSGILTGIMGLISMKAAIWTAGAGEYILDLYSWLCEKASGSSGAVIVTGHPP HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCCCEEEEECCCC EKAVVLYYVFLIVWCVIYYMKVFSGISGKYRNVLPAILYLIITIQLRYNTGCSMKISMLD CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEEECCCCCEEEEEEE VGQGDSIVLQTSDGFNALFDGGSTSKKNIGRYRIYTYLKYAGVRSLDYVFVSHPDKDHIS CCCCCEEEEEECCCCCEEECCCCCCCCCCCCEEHHHHHHHCCCCEEEEEEEECCCHHHHH GIYELIDMCDNTFEIKNIVLPHINDTDETLLEIRKMADRVGINVLYACRGDALSAGNLSI HHHHHHHHCCCCEEECCEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEE SCVHPCKNYNYESANDYSAVYLISFGKFSMLMTGDAESKAEKCLIQDARKSDSVVDLQKL EEECCCCCCCCCCCCCCCEEEEEEECCEEEEEECCCHHHHHHHHHHHHCCCCCEEEHHHH SGINVLKAGHHGSRGASSENFLRFVKPETALISCGVDNSYGHPHNETLQRLKEAGTKVYR CCCCEEECCCCCCCCCCCHHHEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEE TDDRGEIMVRVWEDSYAIEVFGEQKE ECCCCCEEEEEECCCEEEEEECCCCC >Mature Secondary Structure MKRPFFVAAVIGLAAAYLSIYSSGYIVLSAGVIIIACYFIFYKYSKTPLFYILFVLIFPI CCCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH MVIRTEYYSRGMRYQGKLTQDCYAYIKGEAVSVIKGGNSYATRLNNALLIPDWKNNDEKV HHHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEEECCCHHHHHCCCEEEECCCCCCHHHH NESVKSGIIIYSEDSFCHAGDYIWVRVKLKDFEEPTNEGQFNARAYYTSDGINYQGIFNK HHHHHCCEEEEECCCCEECCCEEEEEEEEECCCCCCCCCCCEEEEEEECCCCEECEEECC TVNITPCEGTLKASLLNIADSIKNVYVNTFTQKNAGTMRAIVLGDRSVLDDEIKELYKKN CEEEECCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHC GISHILAISALHITMVGMLVYRMLKKIISVIQAAVLSSVIMLFYLYITGNSVSAGRAVIM CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHH ILVFMLADVLGRTSDGANTLGLAVVILIIRNPYCISNAGFLMSFLAMAGIIFVKPIFSNE HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHEEEEECCCC ETIMLFFRKKKMVSITEMFIYHNIIDMLITGLCVQIATLPVVLSMSGQIAIISLLLNIVV CEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHH IPLMSVIMVSGILTGIMGLISMKAAIWTAGAGEYILDLYSWLCEKASGSSGAVIVTGHPP HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCCCEEEEECCCC EKAVVLYYVFLIVWCVIYYMKVFSGISGKYRNVLPAILYLIITIQLRYNTGCSMKISMLD CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEEECCCCCEEEEEEE VGQGDSIVLQTSDGFNALFDGGSTSKKNIGRYRIYTYLKYAGVRSLDYVFVSHPDKDHIS CCCCCEEEEEECCCCCEEECCCCCCCCCCCCEEHHHHHHHCCCCEEEEEEEECCCHHHHH GIYELIDMCDNTFEIKNIVLPHINDTDETLLEIRKMADRVGINVLYACRGDALSAGNLSI HHHHHHHHCCCCEEECCEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEE SCVHPCKNYNYESANDYSAVYLISFGKFSMLMTGDAESKAEKCLIQDARKSDSVVDLQKL EEECCCCCCCCCCCCCCCEEEEEEECCEEEEEECCCHHHHHHHHHHHHCCCCCEEEHHHH SGINVLKAGHHGSRGASSENFLRFVKPETALISCGVDNSYGHPHNETLQRLKEAGTKVYR CCCCEEECCCCCCCCCCCHHHEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEE TDDRGEIMVRVWEDSYAIEVFGEQKE ECCCCCEEEEEECCCEEEEEECCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7968523; 8969508; 9384377 [H]