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The map label for this gene is hisK [H]

Identifier: 238917121

GI number: 238917121

Start: 1205816

End: 1206640

Strand: Direct

Name: hisK [H]

Synonym: EUBELI_01192

Alternate gene names: 238917121

Gene position: 1205816-1206640 (Clockwise)

Preceding gene: 238917104

Following gene: 238917125

Centisome position: 56.24

GC content: 35.15

Gene sequence:

>825_bases
ATGGAGGACATTACTATGCTGTTATCAGATTCACATATACATACTATGTTCTCTTCTGATTCAGAGGAGAACCCTGTAAA
TGTTGTTAACAATGCTATTTCACTGGGATTTAAACACATCTGTTTTACCGACCATAATGACTTTGATGCTCCTTTAGAAG
ATGGAAAAGTCATGTTTAACCTTGATTTTCCGGAATACATTAAGTATTTCCAGAATCTGAAAGAATCATACAAAAATAAA
ATCAATATTCACATAGGTGTTGAACAGGGACTTATGAGAAGTGTCGCAGACAGAGTCAATTCATACGATTCTGCAAAACA
GCTTGATTTTATAATAGGCTCGTCACATCTTGTATATGGAGAAGATCCCTACTACCCTGAATTCTGGGAGAAACGTTCTA
CAAAGGATACTGTTTTAACTTATTACGAAAGTATTCTTGATAATCTTGGCTGTTGTCACAACTTTGATGTGTATGGTCAT
CTTGATTATATTGCAAGATATATTCCTGCCAATTCTTACGCATATGACTGGCATGATTTTGATGATTTAATTAATACCAT
CCTCAAAACAATCATTGAGAAAGGCAAAGGTATTGAAATCAACACTGCCGGTCTTAAATACGGAATGCCTGAACCTAATC
CATGCCTTGATATTGTTAAAATCTATCACAACCTCGGAGGAGAGATAATCACTGTAGGTTCTGATGCACACGAAGTTAAG
TTTTTTGCTTACAGATTTGATGTCGTGTCAGATATGCTTAAAAACGCGGGGTTTAATTATTACACCATATTTAATGAAAG
AAAGCCTGAGTTCATCAGATTATGA

Upstream 100 bases:

>100_bases
TTAGTTTACATGTTCTACATAAACATCAAAAATATCAATTGCGGATTAATTATGTTTATGTATAATGTATATTGACATTT
AAGCATATGACTAATATTTG

Downstream 100 bases:

>100_bases
TGAGCTCAGGCTTATTTTATATACATGTATCTTATCTGCACCTTCTACATACATCTGTAAAATCTGAAGCTGTAAGATGG
AAGAACTATTTTTCCAGATA

Product: histidinol-phosphatase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MEDITMLLSDSHIHTMFSSDSEENPVNVVNNAISLGFKHICFTDHNDFDAPLEDGKVMFNLDFPEYIKYFQNLKESYKNK
INIHIGVEQGLMRSVADRVNSYDSAKQLDFIIGSSHLVYGEDPYYPEFWEKRSTKDTVLTYYESILDNLGCCHNFDVYGH
LDYIARYIPANSYAYDWHDFDDLINTILKTIIEKGKGIEINTAGLKYGMPEPNPCLDIVKIYHNLGGEIITVGSDAHEVK
FFAYRFDVVSDMLKNAGFNYYTIFNERKPEFIRL

Sequences:

>Translated_274_residues
MEDITMLLSDSHIHTMFSSDSEENPVNVVNNAISLGFKHICFTDHNDFDAPLEDGKVMFNLDFPEYIKYFQNLKESYKNK
INIHIGVEQGLMRSVADRVNSYDSAKQLDFIIGSSHLVYGEDPYYPEFWEKRSTKDTVLTYYESILDNLGCCHNFDVYGH
LDYIARYIPANSYAYDWHDFDDLINTILKTIIEKGKGIEINTAGLKYGMPEPNPCLDIVKIYHNLGGEIITVGSDAHEVK
FFAYRFDVVSDMLKNAGFNYYTIFNERKPEFIRL
>Mature_274_residues
MEDITMLLSDSHIHTMFSSDSEENPVNVVNNAISLGFKHICFTDHNDFDAPLEDGKVMFNLDFPEYIKYFQNLKESYKNK
INIHIGVEQGLMRSVADRVNSYDSAKQLDFIIGSSHLVYGEDPYYPEFWEKRSTKDTVLTYYESILDNLGCCHNFDVYGH
LDYIARYIPANSYAYDWHDFDDLINTILKTIIEKGKGIEINTAGLKYGMPEPNPCLDIVKIYHNLGGEIITVGSDAHEVK
FFAYRFDVVSDMLKNAGFNYYTIFNERKPEFIRL

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 31695; Mature: 31695

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDITMLLSDSHIHTMFSSDSEENPVNVVNNAISLGFKHICFTDHNDFDAPLEDGKVMFN
CCCEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHCEEEEEEECCCCCCCCCCCCEEEEE
LDFPEYIKYFQNLKESYKNKINIHIGVEQGLMRSVADRVNSYDSAKQLDFIIGSSHLVYG
CCCHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHCCCCHHHEEEEECCCEEEEC
EDPYYPEFWEKRSTKDTVLTYYESILDNLGCCHNFDVYGHLDYIARYIPANSYAYDWHDF
CCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEECHHHHHHHCCCCCCEECCCCH
DDLINTILKTIIEKGKGIEINTAGLKYGMPEPNPCLDIVKIYHNLGGEIITVGSDAHEVK
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCHHE
FFAYRFDVVSDMLKNAGFNYYTIFNERKPEFIRL
EHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MEDITMLLSDSHIHTMFSSDSEENPVNVVNNAISLGFKHICFTDHNDFDAPLEDGKVMFN
CCCEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHCEEEEEEECCCCCCCCCCCCEEEEE
LDFPEYIKYFQNLKESYKNKINIHIGVEQGLMRSVADRVNSYDSAKQLDFIIGSSHLVYG
CCCHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHCCCCHHHEEEEECCCEEEEC
EDPYYPEFWEKRSTKDTVLTYYESILDNLGCCHNFDVYGHLDYIARYIPANSYAYDWHDF
CCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEECHHHHHHHCCCCCCEECCCCH
DDLINTILKTIIEKGKGIEINTAGLKYGMPEPNPCLDIVKIYHNLGGEIITVGSDAHEVK
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCHHE
FFAYRFDVVSDMLKNAGFNYYTIFNERKPEFIRL
EHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400209; 11337471 [H]