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The map label for this gene is pgsA [H]

Identifier: 238917053

GI number: 238917053

Start: 1133311

End: 1133853

Strand: Reverse

Name: pgsA [H]

Synonym: EUBELI_01123

Alternate gene names: 238917053

Gene position: 1133853-1133311 (Counterclockwise)

Preceding gene: 238917054

Following gene: 238917052

Centisome position: 52.88

GC content: 30.76

Gene sequence:

>543_bases
ATGAATTTACCTAACAAACTTACAATTGCAAGAGTTATTATGATTCCTTTGTTTCTGATATGTCTGTATCTTAACATTGG
ATGTGGCAAATATATTGCAGTAGGAATATTTATTCTTGCAAGTTTAACAGACCTTTTAGATGGTAAGATTGCAAGAAAGT
ATAATCTTGTTACTAACTTCGGAAAATTTATGGATCCACTTGCAGATAAGCTTTTAGTATGCTCTGCACTTATTGCACTT
GTTGACCTTGAAAGAATTGCAGCATGGATTGTTATTATTATAATTGCAAGAGAATTTATTATTAGCGGATTCAGACTTGT
TGCATCAGATAATGGTGTTGTTATAGCAGCAAGCTACTGGGGCAAGTTCAAGACAGCATTTCAGATGATTACAATTATTA
TGCTTGTTCTTAATCTTAGTGTACCATTTATGAATATTATTAATACTGTTCTCATATATATATCATTAGGATTGACAGTG
ATTTCTCTTATTGATTATATTGCAAAGAATTATAAAGTTTTTCTGGAAGGTTCGGGTAAATAA

Upstream 100 bases:

>100_bases
TGAATGTGACAGGGAACTTATGTCAGGAGATTTTGTATCTGTAAAGATTACCAGTTCAACTGAATATGATTTAATGGGAA
TAATGGAGGAAAATGTTTAA

Downstream 100 bases:

>100_bases
TAATGGTTGATTATCTCGGCTGTCTTGATAAGGCTCTTGTTGAGACATTAAAGAACAAATCCCTGACTATAACTACAGCT
GAGTCATGCACAGGCGGCAT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MNLPNKLTIARVIMIPLFLICLYLNIGCGKYIAVGIFILASLTDLLDGKIARKYNLVTNFGKFMDPLADKLLVCSALIAL
VDLERIAAWIVIIIIAREFIISGFRLVASDNGVVIAASYWGKFKTAFQMITIIMLVLNLSVPFMNIINTVLIYISLGLTV
ISLIDYIAKNYKVFLEGSGK

Sequences:

>Translated_180_residues
MNLPNKLTIARVIMIPLFLICLYLNIGCGKYIAVGIFILASLTDLLDGKIARKYNLVTNFGKFMDPLADKLLVCSALIAL
VDLERIAAWIVIIIIAREFIISGFRLVASDNGVVIAASYWGKFKTAFQMITIIMLVLNLSVPFMNIINTVLIYISLGLTV
ISLIDYIAKNYKVFLEGSGK
>Mature_180_residues
MNLPNKLTIARVIMIPLFLICLYLNIGCGKYIAVGIFILASLTDLLDGKIARKYNLVTNFGKFMDPLADKLLVCSALIAL
VDLERIAAWIVIIIIAREFIISGFRLVASDNGVVIAASYWGKFKTAFQMITIIMLVLNLSVPFMNIINTVLIYISLGLTV
ISLIDYIAKNYKVFLEGSGK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=173, Percent_Identity=35.2601156069364, Blast_Score=104, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6320059, Length=158, Percent_Identity=34.8101265822785, Blast_Score=62, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24650130, Length=173, Percent_Identity=29.4797687861272, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24650126, Length=173, Percent_Identity=29.4797687861272, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24650128, Length=173, Percent_Identity=29.4797687861272, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 19940; Mature: 19940

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPNKLTIARVIMIPLFLICLYLNIGCGKYIAVGIFILASLTDLLDGKIARKYNLVTNF
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GKFMDPLADKLLVCSALIALVDLERIAAWIVIIIIAREFIISGFRLVASDNGVVIAASYW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCEEEEEHHH
GKFKTAFQMITIIMLVLNLSVPFMNIINTVLIYISLGLTVISLIDYIAKNYKVFLEGSGK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
>Mature Secondary Structure
MNLPNKLTIARVIMIPLFLICLYLNIGCGKYIAVGIFILASLTDLLDGKIARKYNLVTNF
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GKFMDPLADKLLVCSALIALVDLERIAAWIVIIIIAREFIISGFRLVASDNGVVIAASYW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCEEEEEHHH
GKFKTAFQMITIIMLVLNLSVPFMNIINTVLIYISLGLTVISLIDYIAKNYKVFLEGSGK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]