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The map label for this gene is pdp [H]

Identifier: 238917042

GI number: 238917042

Start: 1121558

End: 1122862

Strand: Reverse

Name: pdp [H]

Synonym: EUBELI_01112

Alternate gene names: 238917042

Gene position: 1122862-1121558 (Counterclockwise)

Preceding gene: 238917043

Following gene: 238917041

Centisome position: 52.37

GC content: 40.61

Gene sequence:

>1305_bases
ATGAGAATGGTTGATATTATAGAGAAGAAAAGAGATGGTGGAAAGCTTACTAAAGAAGAGATAGAGTTCTTTGTTAATGG
CTATGTCAGGGGGGATATACCTGATTATCAGGCTTCTGCCCTTCTTATGGCAATATATTTCAGACATATGGATTATGATG
AGACTCTTAACCTGACGCTTGCAATGGAAAACAGCGGAGACAAGCTGGATTTGTCGGATATTAATGGAATTAAAGTAGAC
AAGCACAGTACAGGTGGCGTTGGAGATAAGACTTCGCTTGTTCTTGCACCTATGGTTGCAGCACTTGGCGGCAAAGTTGC
AAAGATGAGTGGAAGAGGACTTGGACATACAGGAGGCACGATTGATAAACTGGAAAGTATTCCGGGATTTAACACTTCTC
TGTCTGAGGAAGCATTTGTTAAGCAGGTTAATGATATAGGAATTGCAATAACAGGGCAGACAGGTAATCTTGCACCTGCA
GATAAGAAGATATATGCACTAAGGGATGTTACGGCAACGGTCGAGAATATTTCGCTTATTGCAAGCAGTATTATGAGTAA
GAAACTGGCTTCTGGTGCTGATGCGATTGTTCTTGATGTCAAGACCGGAAGCGGCGCATTTATGAAAAATGAGACTGATG
CCGTAAGTCTTGCTAAGGAGATGGTTCGTATTGGAAAAGGCGCTGGAAGAAATGTAACAGCACTTATTACTGATATGGAC
CAGCCGTTAGGATATGCAGTTGGAAATGCACTTGAAGTTATCGAGGCTATCAATACTTTAAAAGGTGAAGGACCAGAGGA
TTTAACTAAGCTTGTCCTTAATCTTGGAACATATATGGTGCTTGCTGCAAGAGATGACCTTGATAAAGAAACTGTAAGAA
AAGAATTGGAGAGAGTAATAAGTGACGGAAGTGCGTTGGACAAGATGGCAGAGTTCGTTAAAGCCCAGGGTGGAGATCCT
GACGCAGTATATAACACAGATAAGTTAAAGATATCTGATACAATAACAGAGGTGTGTGCAGATAGCGATGGATACATCCA
GTCAATCCAGTCTGAGCTGATAGGAAAATCTTCAATGATTCTTGGAGGCGGAAGGGCAGCCAAGGACGATGTGATTGATT
TATCAGTTGGAGTTGTGCTTTCTAAGAAAATAGGCGACAAAGTCAGCAAAGGTGATGTGATTGCAAGAATTTACTGTGAT
AATGCAGAAAAGACTAAAGAAGCAGAAACAATGATTAAGGATGCGTATACATTTTCGCGAGAATTTGTCGAAAAAAATGT
ACTTATAAAGGGAATAGTTGGTTAA

Upstream 100 bases:

>100_bases
TTATGCTGATATAGCACAGACACTGGCTGAGATTTTTGGCACAGAACCGGTTAAGATAGGAAAGAGTTTTCTTAATAAGA
TTATGTAGGAGGTCTGCATT

Downstream 100 bases:

>100_bases
TAGTTGTAAATAATTGGTTTTTGTGGTATTATAAACACCAAACGGGGCTTTGCCCTAGGTTTGTGAATTGAAAAGGAGAG
TTACGATGGAAGTAAGACAG

Product: pyrimidine-nucleoside phosphorylase

Products: NA

Alternate protein names: PYNP [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MRMVDIIEKKRDGGKLTKEEIEFFVNGYVRGDIPDYQASALLMAIYFRHMDYDETLNLTLAMENSGDKLDLSDINGIKVD
KHSTGGVGDKTSLVLAPMVAALGGKVAKMSGRGLGHTGGTIDKLESIPGFNTSLSEEAFVKQVNDIGIAITGQTGNLAPA
DKKIYALRDVTATVENISLIASSIMSKKLASGADAIVLDVKTGSGAFMKNETDAVSLAKEMVRIGKGAGRNVTALITDMD
QPLGYAVGNALEVIEAINTLKGEGPEDLTKLVLNLGTYMVLAARDDLDKETVRKELERVISDGSALDKMAEFVKAQGGDP
DAVYNTDKLKISDTITEVCADSDGYIQSIQSELIGKSSMILGGGRAAKDDVIDLSVGVVLSKKIGDKVSKGDVIARIYCD
NAEKTKEAETMIKDAYTFSREFVEKNVLIKGIVG

Sequences:

>Translated_434_residues
MRMVDIIEKKRDGGKLTKEEIEFFVNGYVRGDIPDYQASALLMAIYFRHMDYDETLNLTLAMENSGDKLDLSDINGIKVD
KHSTGGVGDKTSLVLAPMVAALGGKVAKMSGRGLGHTGGTIDKLESIPGFNTSLSEEAFVKQVNDIGIAITGQTGNLAPA
DKKIYALRDVTATVENISLIASSIMSKKLASGADAIVLDVKTGSGAFMKNETDAVSLAKEMVRIGKGAGRNVTALITDMD
QPLGYAVGNALEVIEAINTLKGEGPEDLTKLVLNLGTYMVLAARDDLDKETVRKELERVISDGSALDKMAEFVKAQGGDP
DAVYNTDKLKISDTITEVCADSDGYIQSIQSELIGKSSMILGGGRAAKDDVIDLSVGVVLSKKIGDKVSKGDVIARIYCD
NAEKTKEAETMIKDAYTFSREFVEKNVLIKGIVG
>Mature_434_residues
MRMVDIIEKKRDGGKLTKEEIEFFVNGYVRGDIPDYQASALLMAIYFRHMDYDETLNLTLAMENSGDKLDLSDINGIKVD
KHSTGGVGDKTSLVLAPMVAALGGKVAKMSGRGLGHTGGTIDKLESIPGFNTSLSEEAFVKQVNDIGIAITGQTGNLAPA
DKKIYALRDVTATVENISLIASSIMSKKLASGADAIVLDVKTGSGAFMKNETDAVSLAKEMVRIGKGAGRNVTALITDMD
QPLGYAVGNALEVIEAINTLKGEGPEDLTKLVLNLGTYMVLAARDDLDKETVRKELERVISDGSALDKMAEFVKAQGGDP
DAVYNTDKLKISDTITEVCADSDGYIQSIQSELIGKSSMILGGGRAAKDDVIDLSVGVVLSKKIGDKVSKGDVIARIYCD
NAEKTKEAETMIKDAYTFSREFVEKNVLIKGIVG

Specific function: The Enzymes Which Catalyze The Reversible Phosphorolysis Of Pyrimidine Nucleosides Are Involved In The Degradation Of These Compounds And In Their Utilization As Carbon And Energy Sources, Or In The Rescue Of Pyrimidine Bases For Nucleotide Synthesis. [C

COG id: COG0213

COG function: function code F; Thymidine phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI166158925, Length=428, Percent_Identity=39.7196261682243, Blast_Score=287, Evalue=1e-77,
Organism=Homo sapiens, GI4503445, Length=428, Percent_Identity=39.7196261682243, Blast_Score=287, Evalue=1e-77,
Organism=Homo sapiens, GI166158922, Length=428, Percent_Identity=39.7196261682243, Blast_Score=287, Evalue=1e-77,
Organism=Escherichia coli, GI1790842, Length=408, Percent_Identity=45.0980392156863, Blast_Score=326, Evalue=2e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR013102
- InterPro:   IPR018090
- InterPro:   IPR000053
- InterPro:   IPR017872 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; PF07831 PYNP_C [H]

EC number: =2.4.2.2 [H]

Molecular weight: Translated: 46366; Mature: 46366

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00647 THYMID_PHOSPHORYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMVDIIEKKRDGGKLTKEEIEFFVNGYVRGDIPDYQASALLMAIYFRHMDYDETLNLTL
CCCHHHHHHCCCCCCCCHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEE
AMENSGDKLDLSDINGIKVDKHSTGGVGDKTSLVLAPMVAALGGKVAKMSGRGLGHTGGT
EECCCCCEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCC
IDKLESIPGFNTSLSEEAFVKQVNDIGIAITGQTGNLAPADKKIYALRDVTATVENISLI
HHHHHCCCCCCCCCCHHHHHHHHHHCEEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHH
ASSIMSKKLASGADAIVLDVKTGSGAFMKNETDAVSLAKEMVRIGKGAGRNVTALITDMD
HHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCC
QPLGYAVGNALEVIEAINTLKGEGPEDLTKLVLNLGTYMVLAARDDLDKETVRKELERVI
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHH
SDGSALDKMAEFVKAQGGDPDAVYNTDKLKISDTITEVCADSDGYIQSIQSELIGKSSMI
CCCHHHHHHHHHHHHCCCCCCCEECCCCEEEHHHHHHHHCCCCHHHHHHHHHHCCCCCEE
LGGGRAAKDDVIDLSVGVVLSKKIGDKVSKGDVIARIYCDNAEKTKEAETMIKDAYTFSR
EECCCCCCCCEEEEHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
EFVEKNVLIKGIVG
HHHHHCCEEEECCC
>Mature Secondary Structure
MRMVDIIEKKRDGGKLTKEEIEFFVNGYVRGDIPDYQASALLMAIYFRHMDYDETLNLTL
CCCHHHHHHCCCCCCCCHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEE
AMENSGDKLDLSDINGIKVDKHSTGGVGDKTSLVLAPMVAALGGKVAKMSGRGLGHTGGT
EECCCCCEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCC
IDKLESIPGFNTSLSEEAFVKQVNDIGIAITGQTGNLAPADKKIYALRDVTATVENISLI
HHHHHCCCCCCCCCCHHHHHHHHHHCEEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHH
ASSIMSKKLASGADAIVLDVKTGSGAFMKNETDAVSLAKEMVRIGKGAGRNVTALITDMD
HHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCC
QPLGYAVGNALEVIEAINTLKGEGPEDLTKLVLNLGTYMVLAARDDLDKETVRKELERVI
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHH
SDGSALDKMAEFVKAQGGDPDAVYNTDKLKISDTITEVCADSDGYIQSIQSELIGKSSMI
CCCHHHHHHHHHHHHCCCCCCCEECCCCEEEHHHHHHHHCCCCHHHHHHHHHHCCCCCEE
LGGGRAAKDDVIDLSVGVVLSKKIGDKVSKGDVIARIYCDNAEKTKEAETMIKDAYTFSR
EECCCCCCCCEEEEHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
EFVEKNVLIKGIVG
HHHHHCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA