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The map label for this gene is yocR [H]

Identifier: 238917008

GI number: 238917008

Start: 1090896

End: 1092245

Strand: Reverse

Name: yocR [H]

Synonym: EUBELI_01078

Alternate gene names: 238917008

Gene position: 1092245-1090896 (Counterclockwise)

Preceding gene: 238917009

Following gene: 238917007

Centisome position: 50.94

GC content: 35.85

Gene sequence:

>1350_bases
ATGGAAAGAGAGAAATTTGGCAGCAGACTTGGATTCATACTTATAAGTGCAGGCTGCGCAATCGGAATTGGAAATGTATG
GCGTTTTCCATATGTTGCAGGCAATAACGGAGGTGGAATATTTGTTTTATTATATATGTTGTTCCTTCTTATGTTTGGAA
TTCCTGTACTATCAATGGAACTTGCAATGGGAAGAGCTTCTAAAAGCAGTATAATAAGGGCATATCATGAATTGGAGCAA
CCTGGACAGAAGTGGCATATTCATGGATATCTTGGAATGATAGGCAATTATATACTTTTATTCTTCTATACTACTGTTTC
AGGATGGATGTTAGGATATTTTATCAAGTATGTAACTGGTGATATTACTAAAAACACTGACAGTTCACAGATGTTTGCTG
ATGTAACTGCTAATCCATGGATAATGTTTGTGTGGATGGCAGTAATAGTTCTTATTGCGGTTATTGTTTGCAGTATGGGA
CTTCAGAATGGTGTTGAGAAGATTACAAAATATATGATGCTTATTCTTCTTGGACTTATTGTTGTTCTTGCTATCCACAG
TCTTACACTTGATGGTGCCGGAAAAGGAATGCAATATTTTCTTGTTCCTGATATGGATAAGATAAAAGAGGTTGGCCTTG
GAAATATTATTATTGAGGCAATGAGGCAGGCTTTCTTTACTTTAAGTGTAGGAATGGGTTCAATGATGATATTTGGAAGT
TATATTGGGAAAGAACGTGCGCTTGTAGGAGAGGGAATACAGATTACATTACTTGACACATTTGTTGCAATTATGTCAGG
AGTTATCATATTTCCAGCATGTATGTCATATAATATACCAACAGACAGTGGTCCAAGCCTTATATTTGTCACACTTCCAA
AGGTGTTCGAACATATGTCAGGTGGAAGATTCTGGGGCACAATGTTTTTTCTTTTTATGACATTTGCGGCATTATCCACA
GTTATTGCTGTTCTGGAGAATATTATTGCATGCAATATGGAAGCTTTTGGATGGAACCGTAAGAAAGCAGGTGTAATTAA
CCTGTTTATTATAATTATCATGAGTATTCCATGCATTCTTGGCTTCAATGTATTAAGTGGATTTACACCGCTTGGTGCTG
GAACTAATGTGCTTGATCTGGAAGATTTCCTTGTAAGCAGCCTTATTCTCCCTATAGGAAGCCTTGTTATACTTCTTTTC
TGTACGACTAAGCATGGCTGGGGATATGATAATTATATGAATGAAGTTAATACAGGAAAGGGTATTGGCATGCCTAAGAT
TTTTAAGTTTTATCTTAAATATATCCTGCCTCTGGTTATTTTATTCATTATTATTGATGGTTTGATTTAA

Upstream 100 bases:

>100_bases
TGTATTTGTAGATGATTCTACTTGCGGATATGGTATATTTATTGATAGAATGCTTGATAAAGACGAAAAAGAAACTAATT
AAGAAAAGGATTATGATACG

Downstream 100 bases:

>100_bases
TAATCATAAATATGTGTCGAATTTTGTCGAATGCTGCGATATCTTGCGATAAAAAGTGCTTGCGGACTGCTGCTGTTAAA
ACTATACTAGTTGTTGTGAA

Product: neurotransmitter:Na+ symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MEREKFGSRLGFILISAGCAIGIGNVWRFPYVAGNNGGGIFVLLYMLFLLMFGIPVLSMELAMGRASKSSIIRAYHELEQ
PGQKWHIHGYLGMIGNYILLFFYTTVSGWMLGYFIKYVTGDITKNTDSSQMFADVTANPWIMFVWMAVIVLIAVIVCSMG
LQNGVEKITKYMMLILLGLIVVLAIHSLTLDGAGKGMQYFLVPDMDKIKEVGLGNIIIEAMRQAFFTLSVGMGSMMIFGS
YIGKERALVGEGIQITLLDTFVAIMSGVIIFPACMSYNIPTDSGPSLIFVTLPKVFEHMSGGRFWGTMFFLFMTFAALST
VIAVLENIIACNMEAFGWNRKKAGVINLFIIIIMSIPCILGFNVLSGFTPLGAGTNVLDLEDFLVSSLILPIGSLVILLF
CTTKHGWGYDNYMNEVNTGKGIGMPKIFKFYLKYILPLVILFIIIDGLI

Sequences:

>Translated_449_residues
MEREKFGSRLGFILISAGCAIGIGNVWRFPYVAGNNGGGIFVLLYMLFLLMFGIPVLSMELAMGRASKSSIIRAYHELEQ
PGQKWHIHGYLGMIGNYILLFFYTTVSGWMLGYFIKYVTGDITKNTDSSQMFADVTANPWIMFVWMAVIVLIAVIVCSMG
LQNGVEKITKYMMLILLGLIVVLAIHSLTLDGAGKGMQYFLVPDMDKIKEVGLGNIIIEAMRQAFFTLSVGMGSMMIFGS
YIGKERALVGEGIQITLLDTFVAIMSGVIIFPACMSYNIPTDSGPSLIFVTLPKVFEHMSGGRFWGTMFFLFMTFAALST
VIAVLENIIACNMEAFGWNRKKAGVINLFIIIIMSIPCILGFNVLSGFTPLGAGTNVLDLEDFLVSSLILPIGSLVILLF
CTTKHGWGYDNYMNEVNTGKGIGMPKIFKFYLKYILPLVILFIIIDGLI
>Mature_449_residues
MEREKFGSRLGFILISAGCAIGIGNVWRFPYVAGNNGGGIFVLLYMLFLLMFGIPVLSMELAMGRASKSSIIRAYHELEQ
PGQKWHIHGYLGMIGNYILLFFYTTVSGWMLGYFIKYVTGDITKNTDSSQMFADVTANPWIMFVWMAVIVLIAVIVCSMG
LQNGVEKITKYMMLILLGLIVVLAIHSLTLDGAGKGMQYFLVPDMDKIKEVGLGNIIIEAMRQAFFTLSVGMGSMMIFGS
YIGKERALVGEGIQITLLDTFVAIMSGVIIFPACMSYNIPTDSGPSLIFVTLPKVFEHMSGGRFWGTMFFLFMTFAALST
VIAVLENIIACNMEAFGWNRKKAGVINLFIIIIMSIPCILGFNVLSGFTPLGAGTNVLDLEDFLVSSLILPIGSLVILLF
CTTKHGWGYDNYMNEVNTGKGIGMPKIFKFYLKYILPLVILFIIIDGLI

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI4507043, Length=499, Percent_Identity=24.4488977955912, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI171184408, Length=435, Percent_Identity=24.5977011494253, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI171184406, Length=435, Percent_Identity=24.5977011494253, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI171184404, Length=435, Percent_Identity=24.5977011494253, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI289191351, Length=511, Percent_Identity=24.26614481409, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI4557046, Length=511, Percent_Identity=24.26614481409, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI289191377, Length=511, Percent_Identity=23.8747553816047, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI21361581, Length=434, Percent_Identity=23.5023041474654, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI7657587, Length=414, Percent_Identity=23.1884057971014, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI4507041, Length=441, Percent_Identity=24.0362811791383, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI58219014, Length=306, Percent_Identity=25.4901960784314, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI197276623, Length=436, Percent_Identity=24.5412844036697, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI54607094, Length=436, Percent_Identity=24.5412844036697, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI33354281, Length=300, Percent_Identity=22.6666666666667, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI194018524, Length=424, Percent_Identity=23.3490566037736, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI188528618, Length=432, Percent_Identity=21.9907407407407, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI134304856, Length=412, Percent_Identity=25.4854368932039, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI11181770, Length=307, Percent_Identity=25.4071661237785, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI5032097, Length=366, Percent_Identity=25.9562841530055, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI51468073, Length=302, Percent_Identity=22.8476821192053, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI218563756, Length=363, Percent_Identity=26.1707988980716, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI12408638, Length=285, Percent_Identity=24.9122807017544, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI21361693, Length=121, Percent_Identity=34.7107438016529, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI289191353, Length=316, Percent_Identity=23.1012658227848, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI92859670, Length=202, Percent_Identity=25.2475247524752, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI197276625, Length=77, Percent_Identity=40.2597402597403, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI300360519, Length=253, Percent_Identity=20.9486166007905, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI67782313, Length=65, Percent_Identity=46.1538461538462, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI67782315, Length=65, Percent_Identity=46.1538461538462, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI67782317, Length=65, Percent_Identity=46.1538461538462, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17554804, Length=442, Percent_Identity=25.5656108597285, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71998244, Length=347, Percent_Identity=25.3602305475504, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI133952791, Length=323, Percent_Identity=23.8390092879257, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17555248, Length=111, Percent_Identity=32.4324324324324, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25146584, Length=321, Percent_Identity=23.3644859813084, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17542050, Length=125, Percent_Identity=29.6, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71995588, Length=230, Percent_Identity=24.7826086956522, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24762620, Length=399, Percent_Identity=25.8145363408521, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17136952, Length=450, Percent_Identity=22, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281364394, Length=415, Percent_Identity=22.1686746987952, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28574704, Length=415, Percent_Identity=22.1686746987952, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17136950, Length=415, Percent_Identity=22.1686746987952, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28574702, Length=415, Percent_Identity=22.1686746987952, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24639514, Length=515, Percent_Identity=21.9417475728155, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI221329674, Length=515, Percent_Identity=21.9417475728155, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24661428, Length=506, Percent_Identity=24.5059288537549, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24639516, Length=304, Percent_Identity=24.6710526315789, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19921936, Length=346, Percent_Identity=25.4335260115607, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655079, Length=305, Percent_Identity=23.9344262295082, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24582567, Length=467, Percent_Identity=25.0535331905782, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281363702, Length=496, Percent_Identity=22.9838709677419, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24654186, Length=407, Percent_Identity=22.1130221130221, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI19921352, Length=395, Percent_Identity=22.7848101265823, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24584353, Length=395, Percent_Identity=22.7848101265823, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45550877, Length=64, Percent_Identity=51.5625, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI45551183, Length=64, Percent_Identity=51.5625, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI281363700, Length=73, Percent_Identity=38.3561643835616, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24652942, Length=75, Percent_Identity=37.3333333333333, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI45551088, Length=75, Percent_Identity=37.3333333333333, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 49586; Mature: 49586

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEREKFGSRLGFILISAGCAIGIGNVWRFPYVAGNNGGGIFVLLYMLFLLMFGIPVLSME
CCCHHHHHHHHHHHEECCCCCCCCCHHCCCEEECCCCCHHHHHHHHHHHHHHCCHHHHHH
LAMGRASKSSIIRAYHELEQPGQKWHIHGYLGMIGNYILLFFYTTVSGWMLGYFIKYVTG
HHHCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DITKNTDSSQMFADVTANPWIMFVWMAVIVLIAVIVCSMGLQNGVEKITKYMMLILLGLI
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VVLAIHSLTLDGAGKGMQYFLVPDMDKIKEVGLGNIIIEAMRQAFFTLSVGMGSMMIFGS
HHHHHHHHCCCCCCCCCEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
YIGKERALVGEGIQITLLDTFVAIMSGVIIFPACMSYNIPTDSGPSLIFVTLPKVFEHMS
HHCCCHHEECCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHCC
GGRFWGTMFFLFMTFAALSTVIAVLENIIACNMEAFGWNRKKAGVINLFIIIIMSIPCIL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHHHHHH
GFNVLSGFTPLGAGTNVLDLEDFLVSSLILPIGSLVILLFCTTKHGWGYDNYMNEVNTGK
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
GIGMPKIFKFYLKYILPLVILFIIIDGLI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEREKFGSRLGFILISAGCAIGIGNVWRFPYVAGNNGGGIFVLLYMLFLLMFGIPVLSME
CCCHHHHHHHHHHHEECCCCCCCCCHHCCCEEECCCCCHHHHHHHHHHHHHHCCHHHHHH
LAMGRASKSSIIRAYHELEQPGQKWHIHGYLGMIGNYILLFFYTTVSGWMLGYFIKYVTG
HHHCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DITKNTDSSQMFADVTANPWIMFVWMAVIVLIAVIVCSMGLQNGVEKITKYMMLILLGLI
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VVLAIHSLTLDGAGKGMQYFLVPDMDKIKEVGLGNIIIEAMRQAFFTLSVGMGSMMIFGS
HHHHHHHHCCCCCCCCCEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
YIGKERALVGEGIQITLLDTFVAIMSGVIIFPACMSYNIPTDSGPSLIFVTLPKVFEHMS
HHCCCHHEECCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHCC
GGRFWGTMFFLFMTFAALSTVIAVLENIIACNMEAFGWNRKKAGVINLFIIIIMSIPCIL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHHHHHH
GFNVLSGFTPLGAGTNVLDLEDFLVSSLILPIGSLVILLFCTTKHGWGYDNYMNEVNTGK
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
GIGMPKIFKFYLKYILPLVILFIIIDGLI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]