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The map label for this gene is ftsW [H]

Identifier: 238916877

GI number: 238916877

Start: 963168

End: 964544

Strand: Direct

Name: ftsW [H]

Synonym: EUBELI_00946

Alternate gene names: 238916877

Gene position: 963168-964544 (Clockwise)

Preceding gene: 238916876

Following gene: 238916878

Centisome position: 44.92

GC content: 35.73

Gene sequence:

>1377_bases
ATGCAGTCAGTTTTTATTGAACTTACAAAATACATATTTGCGTTTCTGATGGCGTTTTATGTTCTTTCTGCTTACAGAGG
AGCAATAATCCATAAGGAAGAAAAGAGAAAAGGAATATATGTCCAGCAGTATATTATAATATTTGCGATACATTTTCTTG
GATATTATGTATTGTATATAATGAAGCAGGATGTGAAGTATATAGGTTTTTATTTTGTGCAGCTTATATATCTTATAATA
TTCATAGCATTTTATTATATATTGTATCCAAAGGCTTCAAGGCTTCTTGTCAATAATATGTGCATGCTCATGGCGGTAGG
CTTTATCATGATTGCAAGGCTTAATTTTGACAAATGTGTAAAACAGTTCGTAATTGCTGTGCTTGGAACGGTAATAATGT
TTATGGTTCCATGGCTTTTAAAGACAGTTAAAAGCTTTAGAAATTTTGGATGGATATATTGTATCACAGGGCTTGTGCTT
TTATGTGCTGTTTTGTTAGGAAGCAAGGTATATGGTGCAAATCTTACTTTAAGTATTGGCGCGTTTTCTGTACAGCCGGC
AGAGTTTGTTAAGATTTTGTATGTTATGTTTGTTGCTTCGATGTTTAATAAGTCAACGACATTTAAACAGACATGTATTG
TTACAGCGTTTGCAGCACTTCATGTTATTATTCTTGTGCTTTCAACTGACCTTGGTGCTGCACTTATATTCTTTGTGGTG
TATATTGCAATGCTTTATATAGCAACAAGAAAACTGGTCTATGCCGGGGCAGGACTGATTGCCGGAGCAGGTGCATCTGT
TATTGCATATAAGCTTTTTGCACATGTGAGAGCGAGAGTTATTGTATGGCGTAATCCGTGGGAATATATTGATACAAGCG
GATATCAGATATGTCAGTCTCTTTTTGCAATAGGAATGGGGTCATGGTTTGGTTATGGACTGTGTCAGGGTATGCCTGAT
AAGATACCTGTGGCAGAGAAAGATTTTATGTTTTCTGCTATATCTGAAGAATTTGGACTTATATTTTCGATAGCCCTATT
CCTGGTGTGTCTTAATAATCTTATTCTTATGATGAATATAGCTTCAAGATGTAAGACTCTTTTTTATCGTCTTGTGGCAG
TAGGACTTGGTGTTACATATGGGGTTCAGGTGTTCTTAACTGTCGGAGGTGCGATTAAGTTCATACCAATGACAGGCGTT
ACACTTCCTTTTGTAAGTTACGGAGGAAGCTCAATATTAAGCTCACTGATAATGTTTGCATTAATAAATGGAATGTATAC
TATGAGACAGGATGAAGGTGACAGGAAAGATGGCAGAAAACAAAAAGCAGGTCAGACAAAGAAAAAACAAAAATGCACAG
AACGATATAGTAGATAA

Upstream 100 bases:

>100_bases
TATACAATTAGTTATGACTGATGGAGTGTGTGGTGGTACTACAGGGCATTTTCATCAGGCAATCGACTAAGATTAAGTGA
CTTGAATAAAGGAGATTGCT

Downstream 100 bases:

>100_bases
TGAAAAGAAGGATTTAAGAAATAAGGAAACTAATATAATAGCATTCTTTTTTGTAGGACTTTTTATGGCTACAATTGTTT
ATCTGTGCGTATTCAATATA

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MQSVFIELTKYIFAFLMAFYVLSAYRGAIIHKEEKRKGIYVQQYIIIFAIHFLGYYVLYIMKQDVKYIGFYFVQLIYLII
FIAFYYILYPKASRLLVNNMCMLMAVGFIMIARLNFDKCVKQFVIAVLGTVIMFMVPWLLKTVKSFRNFGWIYCITGLVL
LCAVLLGSKVYGANLTLSIGAFSVQPAEFVKILYVMFVASMFNKSTTFKQTCIVTAFAALHVIILVLSTDLGAALIFFVV
YIAMLYIATRKLVYAGAGLIAGAGASVIAYKLFAHVRARVIVWRNPWEYIDTSGYQICQSLFAIGMGSWFGYGLCQGMPD
KIPVAEKDFMFSAISEEFGLIFSIALFLVCLNNLILMMNIASRCKTLFYRLVAVGLGVTYGVQVFLTVGGAIKFIPMTGV
TLPFVSYGGSSILSSLIMFALINGMYTMRQDEGDRKDGRKQKAGQTKKKQKCTERYSR

Sequences:

>Translated_458_residues
MQSVFIELTKYIFAFLMAFYVLSAYRGAIIHKEEKRKGIYVQQYIIIFAIHFLGYYVLYIMKQDVKYIGFYFVQLIYLII
FIAFYYILYPKASRLLVNNMCMLMAVGFIMIARLNFDKCVKQFVIAVLGTVIMFMVPWLLKTVKSFRNFGWIYCITGLVL
LCAVLLGSKVYGANLTLSIGAFSVQPAEFVKILYVMFVASMFNKSTTFKQTCIVTAFAALHVIILVLSTDLGAALIFFVV
YIAMLYIATRKLVYAGAGLIAGAGASVIAYKLFAHVRARVIVWRNPWEYIDTSGYQICQSLFAIGMGSWFGYGLCQGMPD
KIPVAEKDFMFSAISEEFGLIFSIALFLVCLNNLILMMNIASRCKTLFYRLVAVGLGVTYGVQVFLTVGGAIKFIPMTGV
TLPFVSYGGSSILSSLIMFALINGMYTMRQDEGDRKDGRKQKAGQTKKKQKCTERYSR
>Mature_458_residues
MQSVFIELTKYIFAFLMAFYVLSAYRGAIIHKEEKRKGIYVQQYIIIFAIHFLGYYVLYIMKQDVKYIGFYFVQLIYLII
FIAFYYILYPKASRLLVNNMCMLMAVGFIMIARLNFDKCVKQFVIAVLGTVIMFMVPWLLKTVKSFRNFGWIYCITGLVL
LCAVLLGSKVYGANLTLSIGAFSVQPAEFVKILYVMFVASMFNKSTTFKQTCIVTAFAALHVIILVLSTDLGAALIFFVV
YIAMLYIATRKLVYAGAGLIAGAGASVIAYKLFAHVRARVIVWRNPWEYIDTSGYQICQSLFAIGMGSWFGYGLCQGMPD
KIPVAEKDFMFSAISEEFGLIFSIALFLVCLNNLILMMNIASRCKTLFYRLVAVGLGVTYGVQVFLTVGGAIKFIPMTGV
TLPFVSYGGSSILSSLIMFALINGMYTMRQDEGDRKDGRKQKAGQTKKKQKCTERYSR

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=279, Percent_Identity=31.1827956989247, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786853, Length=322, Percent_Identity=26.7080745341615, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 51655; Mature: 51655

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]