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The map label for this gene is glnS [H]

Identifier: 238916446

GI number: 238916446

Start: 507486

End: 509162

Strand: Direct

Name: glnS [H]

Synonym: EUBELI_00503

Alternate gene names: 238916446

Gene position: 507486-509162 (Clockwise)

Preceding gene: 238916445

Following gene: 238916447

Centisome position: 23.67

GC content: 36.91

Gene sequence:

>1677_bases
ATGGAAAACGAAGCTCTTTCTAAGAACTTTATTGAGCAGATTATAGATAAGGATATTGAGAGTGGCCATTGCAAGAAGGT
CATTACAAGATTTCCACCAGAACCTAATGGATATCTTCATATTGGACATGCCAAGTCTATATTATTGAATTATGGACTTG
CAAAGGAATATGGCGGGCAGTTTAATATGAGATTTGATGATACTAATCCAACTAAAGAAAAGGTTGAATTTGTAGATTCA
ATTAAGGCGGATGTTGAGTGGCTTGGCGCAGAGTGGAATGGAGACGTTCTTTTTGCATCAGATTATTTTCCACAGATGTA
TGAAGCAGCTGTAAAGCTTATCAAGAAGGGAAAAGCTTATGTAGATGATTTGTCTGCTGAGGAGATTAGACAGTACAGAG
GAACTCTTACTGAACCAGGTAAGGAAAGTCCTTATAGAAACCGTTCTGTAGAAGAGAATCTTCAGCTTTTTGAGGAGATG
AAGGAAGGAAAATATGCAGACGGAACGAAGGTTTTAAGAGCAAAGATTGATATGGCATCTCCTAATATTAACATGAGAGA
TCCTATTATTTACAGAGTTGCACATATGACACATCACAGAACAGGAGATCAGTGGTGCATATATCCTATGTATGATTTTG
CACATCCTATTGAAGATGCAGTAGAGGGAATTACACACTCTATATGTACACTTGAGTTTGAGGATCACAGACCTCTTTAT
GACTGGGTTGTAATTGAGACCGGTTATAAGACATCTCCAGAGGAGAATCCTAAGCAGATTGAATTTGCAAAGTTATATCT
TACTAATGTTGTAACAGGTAAGAGATATATTAAGAAGCTTGTAGAAGATGGAATTGTTGACGGATGGGATGATCCAAGAC
TTGTATCTATTGCAGCTTTAAGAAGAAGAGGATTTACTCCTGAAGCTATTAAGATGTTCGTTGAGCTTGTTGGTGTTACT
AAGGCACAGGGTTCAGTTGAATATCCAATGCTTGAATATTGTATAAGAGAAGATTTAAAGCTTAAGGTTAAGAGAATGAT
GGCTGTTCTTGATCCTGTTAAGCTTGTTATTGATAATTATCCTGAAGGCCAGGTTGAATATATGGAAGTGGCTAATAATC
AGGAAAATCCAGAGATGGGAACAAGAAAAGTTCCATTTACAAAGGAACTTTATATTGAGAGAGAGGATTTCATGGAAGAG
CCTCCTAAGAAATATTTCAGACTTTTCCCTGGTAATGAAGTGCGTCTTATGAATGCATATTTTGTTACATGTACTGACTA
TGTCAAGGATGAGAATGGGAAGGTTATAGAAGTACATTGTACTTATGATCCTGAGACTAAGGGTGGAAATTTCACAGGCC
GTAAGGTTAAGGGAACAATACACTGGGTTTCTGCTACAGAAGGCTGTAAAGCAGAAGTCAGATTATACGAGAATATCGTA
GATGAAGAAAAGGGTGTTTATAACGAAGAAGATGGTTCTATGAATATCAATCCGAACTCTAAGACTGTTCTTACAGAGTG
TTATCTTGAACCAGAGCTTATGAAAGCTGTAAGTGAAGATAAGTTCCAGTTTGTAAGAAATGGCTATTTCTGCGTTGATA
ATAAAGATTCAGAGCCGGGTAAGCCTATATTTAACAGGATAGTTTCACTTAAGAGTTCATTCAAATTACAGAAATAG

Upstream 100 bases:

>100_bases
TTAAATACGAAAACAAGGAGGAAAAATCCTCTCCTCACCAGAGGAGAATGTGCTTACAATAAGCACATGGATTTTGCTTC
GCAAAACAAGGAGGATTAAC

Downstream 100 bases:

>100_bases
TGAGGTTATCCTGATGGAAGGTATTGGACAAAAGAAGGAAACAGATTATATTTTTGATAAGACAATCAAATGTGATGTAT
GTGGGAAGGAATTTAAAACA

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MENEALSKNFIEQIIDKDIESGHCKKVITRFPPEPNGYLHIGHAKSILLNYGLAKEYGGQFNMRFDDTNPTKEKVEFVDS
IKADVEWLGAEWNGDVLFASDYFPQMYEAAVKLIKKGKAYVDDLSAEEIRQYRGTLTEPGKESPYRNRSVEENLQLFEEM
KEGKYADGTKVLRAKIDMASPNINMRDPIIYRVAHMTHHRTGDQWCIYPMYDFAHPIEDAVEGITHSICTLEFEDHRPLY
DWVVIETGYKTSPEENPKQIEFAKLYLTNVVTGKRYIKKLVEDGIVDGWDDPRLVSIAALRRRGFTPEAIKMFVELVGVT
KAQGSVEYPMLEYCIREDLKLKVKRMMAVLDPVKLVIDNYPEGQVEYMEVANNQENPEMGTRKVPFTKELYIEREDFMEE
PPKKYFRLFPGNEVRLMNAYFVTCTDYVKDENGKVIEVHCTYDPETKGGNFTGRKVKGTIHWVSATEGCKAEVRLYENIV
DEEKGVYNEEDGSMNINPNSKTVLTECYLEPELMKAVSEDKFQFVRNGYFCVDNKDSEPGKPIFNRIVSLKSSFKLQK

Sequences:

>Translated_558_residues
MENEALSKNFIEQIIDKDIESGHCKKVITRFPPEPNGYLHIGHAKSILLNYGLAKEYGGQFNMRFDDTNPTKEKVEFVDS
IKADVEWLGAEWNGDVLFASDYFPQMYEAAVKLIKKGKAYVDDLSAEEIRQYRGTLTEPGKESPYRNRSVEENLQLFEEM
KEGKYADGTKVLRAKIDMASPNINMRDPIIYRVAHMTHHRTGDQWCIYPMYDFAHPIEDAVEGITHSICTLEFEDHRPLY
DWVVIETGYKTSPEENPKQIEFAKLYLTNVVTGKRYIKKLVEDGIVDGWDDPRLVSIAALRRRGFTPEAIKMFVELVGVT
KAQGSVEYPMLEYCIREDLKLKVKRMMAVLDPVKLVIDNYPEGQVEYMEVANNQENPEMGTRKVPFTKELYIEREDFMEE
PPKKYFRLFPGNEVRLMNAYFVTCTDYVKDENGKVIEVHCTYDPETKGGNFTGRKVKGTIHWVSATEGCKAEVRLYENIV
DEEKGVYNEEDGSMNINPNSKTVLTECYLEPELMKAVSEDKFQFVRNGYFCVDNKDSEPGKPIFNRIVSLKSSFKLQK
>Mature_558_residues
MENEALSKNFIEQIIDKDIESGHCKKVITRFPPEPNGYLHIGHAKSILLNYGLAKEYGGQFNMRFDDTNPTKEKVEFVDS
IKADVEWLGAEWNGDVLFASDYFPQMYEAAVKLIKKGKAYVDDLSAEEIRQYRGTLTEPGKESPYRNRSVEENLQLFEEM
KEGKYADGTKVLRAKIDMASPNINMRDPIIYRVAHMTHHRTGDQWCIYPMYDFAHPIEDAVEGITHSICTLEFEDHRPLY
DWVVIETGYKTSPEENPKQIEFAKLYLTNVVTGKRYIKKLVEDGIVDGWDDPRLVSIAALRRRGFTPEAIKMFVELVGVT
KAQGSVEYPMLEYCIREDLKLKVKRMMAVLDPVKLVIDNYPEGQVEYMEVANNQENPEMGTRKVPFTKELYIEREDFMEE
PPKKYFRLFPGNEVRLMNAYFVTCTDYVKDENGKVIEVHCTYDPETKGGNFTGRKVKGTIHWVSATEGCKAEVRLYENIV
DEEKGVYNEEDGSMNINPNSKTVLTECYLEPELMKAVSEDKFQFVRNGYFCVDNKDSEPGKPIFNRIVSLKSSFKLQK

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=536, Percent_Identity=42.910447761194, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI62241042, Length=525, Percent_Identity=34.8571428571429, Blast_Score=275, Evalue=1e-73,
Organism=Escherichia coli, GI1786895, Length=554, Percent_Identity=53.7906137184115, Blast_Score=601, Evalue=1e-173,
Organism=Escherichia coli, GI1788743, Length=387, Percent_Identity=23.5142118863049, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17543332, Length=539, Percent_Identity=40.0742115027829, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17511007, Length=375, Percent_Identity=38.4, Blast_Score=236, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6324742, Length=565, Percent_Identity=41.0619469026549, Blast_Score=387, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6321192, Length=530, Percent_Identity=34.3396226415094, Blast_Score=280, Evalue=5e-76,
Organism=Saccharomyces cerevisiae, GI6324540, Length=315, Percent_Identity=26.3492063492064, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17864488, Length=535, Percent_Identity=41.8691588785047, Blast_Score=382, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24649466, Length=521, Percent_Identity=33.3973128598848, Blast_Score=255, Evalue=5e-68,
Organism=Drosophila melanogaster, GI24665321, Length=319, Percent_Identity=26.3322884012539, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 64394; Mature: 64394

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENEALSKNFIEQIIDKDIESGHCKKVITRFPPEPNGYLHIGHAKSILLNYGLAKEYGGQ
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEECCHHHHHHHCCHHHHHCCE
FNMRFDDTNPTKEKVEFVDSIKADVEWLGAEWNGDVLFASDYFPQMYEAAVKLIKKGKAY
EEEEECCCCCHHHHHHHHHHHHHHHHEECCCCCCCEEEECCCCHHHHHHHHHHHHCCCHH
VDDLSAEEIRQYRGTLTEPGKESPYRNRSVEENLQLFEEMKEGKYADGTKVLRAKIDMAS
HHCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCC
PNINMRDPIIYRVAHMTHHRTGDQWCIYPMYDFAHPIEDAVEGITHSICTLEFEDHRPLY
CCCCCCCCHHHHHHHHHHCCCCCCEEEEEHHHHCCHHHHHHHHHHHHEEEEEECCCCCCE
DWVVIETGYKTSPEENPKQIEFAKLYLTNVVTGKRYIKKLVEDGIVDGWDDPRLVSIAAL
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
RRRGFTPEAIKMFVELVGVTKAQGSVEYPMLEYCIREDLKLKVKRMMAVLDPVKLVIDNY
HHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PEGQVEYMEVANNQENPEMGTRKVPFTKELYIEREDFMEEPPKKYFRLFPGNEVRLMNAY
CCCCEEHHHHHCCCCCCCCCCCCCCCHHHHEEEHHHHHCCCCHHHHEECCCCCEEEEEEE
FVTCTDYVKDENGKVIEVHCTYDPETKGGNFTGRKVKGTIHWVSATEGCKAEVRLYENIV
EEEEEHHEECCCCCEEEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHH
DEEKGVYNEEDGSMNINPNSKTVLTECYLEPELMKAVSEDKFQFVRNGYFCVDNKDSEPG
HHHCCCCCCCCCCEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
KPIFNRIVSLKSSFKLQK
CHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MENEALSKNFIEQIIDKDIESGHCKKVITRFPPEPNGYLHIGHAKSILLNYGLAKEYGGQ
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEECCHHHHHHHCCHHHHHCCE
FNMRFDDTNPTKEKVEFVDSIKADVEWLGAEWNGDVLFASDYFPQMYEAAVKLIKKGKAY
EEEEECCCCCHHHHHHHHHHHHHHHHEECCCCCCCEEEECCCCHHHHHHHHHHHHCCCHH
VDDLSAEEIRQYRGTLTEPGKESPYRNRSVEENLQLFEEMKEGKYADGTKVLRAKIDMAS
HHCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCC
PNINMRDPIIYRVAHMTHHRTGDQWCIYPMYDFAHPIEDAVEGITHSICTLEFEDHRPLY
CCCCCCCCHHHHHHHHHHCCCCCCEEEEEHHHHCCHHHHHHHHHHHHEEEEEECCCCCCE
DWVVIETGYKTSPEENPKQIEFAKLYLTNVVTGKRYIKKLVEDGIVDGWDDPRLVSIAAL
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
RRRGFTPEAIKMFVELVGVTKAQGSVEYPMLEYCIREDLKLKVKRMMAVLDPVKLVIDNY
HHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PEGQVEYMEVANNQENPEMGTRKVPFTKELYIEREDFMEEPPKKYFRLFPGNEVRLMNAY
CCCCEEHHHHHCCCCCCCCCCCCCCCHHHHEEEHHHHHCCCCHHHHEECCCCCEEEEEEE
FVTCTDYVKDENGKVIEVHCTYDPETKGGNFTGRKVKGTIHWVSATEGCKAEVRLYENIV
EEEEEHHEECCCCCEEEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHH
DEEKGVYNEEDGSMNINPNSKTVLTECYLEPELMKAVSEDKFQFVRNGYFCVDNKDSEPG
HHHCCCCCCCCCCEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
KPIFNRIVSLKSSFKLQK
CHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA