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The map label for this gene is yoeA [H]

Identifier: 238916368

GI number: 238916368

Start: 433396

End: 434763

Strand: Direct

Name: yoeA [H]

Synonym: EUBELI_00421

Alternate gene names: 238916368

Gene position: 433396-434763 (Clockwise)

Preceding gene: 238916367

Following gene: 238916371

Centisome position: 20.21

GC content: 37.13

Gene sequence:

>1368_bases
ATGGCAAATTCACAAAAAGGCAAGATTGATATGACCACAGGTCATATCATGAGAAATATTATACTGTTTGCGATACCGAT
TATTATTGGAAATGTTTTGCAGCAGTTATATACTACGGTTGATGCACTTGTAATAGGTAAATACTGTGGTGATACATCTT
TAGCTGCGGTAGGAACGAGTTCGCAGCCTGTTGAAGTATTATTATGTGTCTTTTTAGGAATAGGAACAGGTGTGTCTATT
CTTATTTCACAATATACCGGGGCCAGGGAATCGAGAAAGGTTGTTTCAGTATGTGGAACTTCAATAACATTTATATATAT
TATAGGTATTCCGATTGGAATTCTTGGATGGTTTGCAGCACCGTATATTCTGGAATTTATGAAAGTGCCGCAGGATGTGT
GGAATGCCGCATTAATCTATACAAGGGTTGTATTCTTAGGCACACTTGGTAATCTGGGGTATAATATGAACGCCGGAATT
TTAAGAGGACTTGGAGACAGCAAGGCTTCGCTATGGTTTCTGGTTGTGTCATGTGTTTCTAATATAGTATTTGATTTATT
GTTTGTTGCAGGTTTTGGAATGGATGTAGCCGGGGCAGCACTTTCTACAAGTATTGCCATGTTTATTTCATGGATTGTAA
GTATTGTTTATATAAGAAAGAAGTTTCCAGAGATACAGTTTACATTTTTGCCGAGAAGATTCTCTGGAACAATGATGAAG
GATATTCTGGCTATTGGCTTACCTGTTGGTCTTAACAATTCGCTTTATTCATTAGGACATGTTGCATTACAGACCTTTAA
TAACTCACAGGGTGCTATATTTATGGCAGGAGGTGCAGTAGCAGGAAGAATTACAGGATGCTCTAACATAGCAATTACCG
GATTGTCTTCGGCGGCCACTACATTTTCAGGACAGAATTACGGTGCTAAGAAATACTCAAGAATTAAAGAAGGACACTGG
AGAATTCCATTGTGTTCAGGTCTTATTACATTAAGTTGTGGATTGTTTTTCATAATGATACATAAACCTATAATACGTTT
CTTTTCATCAGATGAAATGGTATTGATGTATGCGAGCAGGCATGTTGTTGTCATGCTGCTTTCACAGTGGTTTTTTGCTA
TCTTTAACTGTATAATATCTATTGTAAACGGAACCGGAAAGGTGCGTTATACTACAATTGTCAATATTCTTATGCTTTGG
GCGGTCAGAATTCCAAGTGCCTATATTATTAACAGATACTTTGATGGAACATGGGTAATGTTGTGCTTCCCAATTTCTTT
CAGTTTTGGAATGTTTGCAATGATAGGTTATTATCTGTTCTCGCCAGCATGGAAGGAAGTTATGAGAATGGCAGAAAAAA
ATTCATAA

Upstream 100 bases:

>100_bases
TTCTGTACTCCATGCCATAAATCACTAGAATATATAACTCAATTACAGTATTATTATAATTAACAGATACAGACAGGTTA
TTTTATGATAGGAGTATATT

Downstream 100 bases:

>100_bases
TGCCGGTAAAATATAAACCCCTGTATCAACATGCATGGAATTGTTGATACAGGGGTATTAATTTAACAAAATATTATTTC
AGAATAATTACTGAAGGAGT

Product: MATE family multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MANSQKGKIDMTTGHIMRNIILFAIPIIIGNVLQQLYTTVDALVIGKYCGDTSLAAVGTSSQPVEVLLCVFLGIGTGVSI
LISQYTGARESRKVVSVCGTSITFIYIIGIPIGILGWFAAPYILEFMKVPQDVWNAALIYTRVVFLGTLGNLGYNMNAGI
LRGLGDSKASLWFLVVSCVSNIVFDLLFVAGFGMDVAGAALSTSIAMFISWIVSIVYIRKKFPEIQFTFLPRRFSGTMMK
DILAIGLPVGLNNSLYSLGHVALQTFNNSQGAIFMAGGAVAGRITGCSNIAITGLSSAATTFSGQNYGAKKYSRIKEGHW
RIPLCSGLITLSCGLFFIMIHKPIIRFFSSDEMVLMYASRHVVVMLLSQWFFAIFNCIISIVNGTGKVRYTTIVNILMLW
AVRIPSAYIINRYFDGTWVMLCFPISFSFGMFAMIGYYLFSPAWKEVMRMAEKNS

Sequences:

>Translated_455_residues
MANSQKGKIDMTTGHIMRNIILFAIPIIIGNVLQQLYTTVDALVIGKYCGDTSLAAVGTSSQPVEVLLCVFLGIGTGVSI
LISQYTGARESRKVVSVCGTSITFIYIIGIPIGILGWFAAPYILEFMKVPQDVWNAALIYTRVVFLGTLGNLGYNMNAGI
LRGLGDSKASLWFLVVSCVSNIVFDLLFVAGFGMDVAGAALSTSIAMFISWIVSIVYIRKKFPEIQFTFLPRRFSGTMMK
DILAIGLPVGLNNSLYSLGHVALQTFNNSQGAIFMAGGAVAGRITGCSNIAITGLSSAATTFSGQNYGAKKYSRIKEGHW
RIPLCSGLITLSCGLFFIMIHKPIIRFFSSDEMVLMYASRHVVVMLLSQWFFAIFNCIISIVNGTGKVRYTTIVNILMLW
AVRIPSAYIINRYFDGTWVMLCFPISFSFGMFAMIGYYLFSPAWKEVMRMAEKNS
>Mature_454_residues
ANSQKGKIDMTTGHIMRNIILFAIPIIIGNVLQQLYTTVDALVIGKYCGDTSLAAVGTSSQPVEVLLCVFLGIGTGVSIL
ISQYTGARESRKVVSVCGTSITFIYIIGIPIGILGWFAAPYILEFMKVPQDVWNAALIYTRVVFLGTLGNLGYNMNAGIL
RGLGDSKASLWFLVVSCVSNIVFDLLFVAGFGMDVAGAALSTSIAMFISWIVSIVYIRKKFPEIQFTFLPRRFSGTMMKD
ILAIGLPVGLNNSLYSLGHVALQTFNNSQGAIFMAGGAVAGRITGCSNIAITGLSSAATTFSGQNYGAKKYSRIKEGHWR
IPLCSGLITLSCGLFFIMIHKPIIRFFSSDEMVLMYASRHVVVMLLSQWFFAIFNCIISIVNGTGKVRYTTIVNILMLWA
VRIPSAYIINRYFDGTWVMLCFPISFSFGMFAMIGYYLFSPAWKEVMRMAEKNS

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=411, Percent_Identity=22.1411192214112, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790477, Length=201, Percent_Identity=27.8606965174129, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49911; Mature: 49780

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANSQKGKIDMTTGHIMRNIILFAIPIIIGNVLQQLYTTVDALVIGKYCGDTSLAAVGTS
CCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
SQPVEVLLCVFLGIGTGVSILISQYTGARESRKVVSVCGTSITFIYIIGIPIGILGWFAA
CCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHH
PYILEFMKVPQDVWNAALIYTRVVFLGTLGNLGYNMNAGILRGLGDSKASLWFLVVSCVS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHH
NIVFDLLFVAGFGMDVAGAALSTSIAMFISWIVSIVYIRKKFPEIQFTFLPRRFSGTMMK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHCCHHHH
DILAIGLPVGLNNSLYSLGHVALQTFNNSQGAIFMAGGAVAGRITGCSNIAITGLSSAAT
HHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCEEEECCCHHHH
TFSGQNYGAKKYSRIKEGHWRIPLCSGLITLSCGLFFIMIHKPIIRFFSSDEMVLMYASR
CCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECH
HVVVMLLSQWFFAIFNCIISIVNGTGKVRYTTIVNILMLWAVRIPSAYIINRYFDGTWVM
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHEECCEEEE
LCFPISFSFGMFAMIGYYLFSPAWKEVMRMAEKNS
EEEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANSQKGKIDMTTGHIMRNIILFAIPIIIGNVLQQLYTTVDALVIGKYCGDTSLAAVGTS
CCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
SQPVEVLLCVFLGIGTGVSILISQYTGARESRKVVSVCGTSITFIYIIGIPIGILGWFAA
CCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHH
PYILEFMKVPQDVWNAALIYTRVVFLGTLGNLGYNMNAGILRGLGDSKASLWFLVVSCVS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHH
NIVFDLLFVAGFGMDVAGAALSTSIAMFISWIVSIVYIRKKFPEIQFTFLPRRFSGTMMK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHCCHHHH
DILAIGLPVGLNNSLYSLGHVALQTFNNSQGAIFMAGGAVAGRITGCSNIAITGLSSAAT
HHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCEEEECCCHHHH
TFSGQNYGAKKYSRIKEGHWRIPLCSGLITLSCGLFFIMIHKPIIRFFSSDEMVLMYASR
CCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECH
HVVVMLLSQWFFAIFNCIISIVNGTGKVRYTTIVNILMLWAVRIPSAYIINRYFDGTWVM
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHEECCEEEE
LCFPISFSFGMFAMIGYYLFSPAWKEVMRMAEKNS
EEEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]