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The map label for this gene is yybE [H]

Identifier: 238916148

GI number: 238916148

Start: 212088

End: 212945

Strand: Reverse

Name: yybE [H]

Synonym: EUBELI_00182

Alternate gene names: 238916148

Gene position: 212945-212088 (Counterclockwise)

Preceding gene: 238916164

Following gene: 238916144

Centisome position: 9.93

GC content: 42.42

Gene sequence:

>858_bases
ATGGAATTATATCAGCTCAGGCAGTTTCAGGCTGCCGCCAGACACAAGAATATGACCCGTGCTGCCAGTGAACTGTGCAT
AGCACAGCCGGCATTAAGCAAGACAATCCATAAGCTTGAAGAAGAATTTGGCGCACAGCTTTTTATCCGTAATAAAAAAG
GGCTCGAATGTACCCGTCAGGGAGAAATTCTGCTTGAATATGCAGACAGAATACTGGCTCTTTCAGAAGATGCTACGCGT
GCTGTCAGTGAAAGTCTTGGCGATGCAGGCGACATAAGGCTCTGTCTCCGCTCAAGTGCAGTTCTTGTCAGCAATGTACT
TAAAGATTTTATCCATGAGCACCCTCATGTCAGCTTTTCAATATCTTCTGAACCAAAAGGGTGTGACCTGCTGATTGACT
CTGTCTCATCAGCTTATGATATTCCAGACAATGCACATCTTCTTATGACAGAAGAAATCTGCCTTGCCGTTTCATCATCA
CATCCACTTGCCCATACCGGACACATATCAGTAGAACAGATGATGAATGAGAAATTCATTGACCTTGCAGATACTCCATC
TTATGCCGGAGTGTTCAATTCAATATTCAGTAAATGTAAGAAAACTCCTCAGATAGCCTACTCATGCAATGATTACATAT
TACAGGGCAAACTCATAAGTCTCGGTCTTGGAGTATCATTTGTTGCCTCTGTAACATGGACAAGCAGCAGCCTTCCTGAA
AACATAAGCCTGCTGCATATAGATGACTGTCCACATTTCAGAAGCATTTATTATCAGCCGCTTGGCTCATTCTGCTCAGA
AAATCAGCGAATCTTCGAGCACCAGCTTGAAGAATATTTCAAAAATTTGAATAATTAA

Upstream 100 bases:

>100_bases
CGTTAATAATATTTGTGTTATCATAATCGTAAATATCCTGATTTCTATATTATGTTAATTGTAATTTTTATAAAATACTA
CATACAAGAGAGGTGCGAAC

Downstream 100 bases:

>100_bases
TGCACCTCTAATGGTGTGTCTTCACCGGCTGCAAACTGCACAACACTCTTAACTGAAGACTCAACCATGTCAGACACAGC
CTGATCTGTGAAAAATGCAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MELYQLRQFQAAARHKNMTRAASELCIAQPALSKTIHKLEEEFGAQLFIRNKKGLECTRQGEILLEYADRILALSEDATR
AVSESLGDAGDIRLCLRSSAVLVSNVLKDFIHEHPHVSFSISSEPKGCDLLIDSVSSAYDIPDNAHLLMTEEICLAVSSS
HPLAHTGHISVEQMMNEKFIDLADTPSYAGVFNSIFSKCKKTPQIAYSCNDYILQGKLISLGLGVSFVASVTWTSSSLPE
NISLLHIDDCPHFRSIYYQPLGSFCSENQRIFEHQLEEYFKNLNN

Sequences:

>Translated_285_residues
MELYQLRQFQAAARHKNMTRAASELCIAQPALSKTIHKLEEEFGAQLFIRNKKGLECTRQGEILLEYADRILALSEDATR
AVSESLGDAGDIRLCLRSSAVLVSNVLKDFIHEHPHVSFSISSEPKGCDLLIDSVSSAYDIPDNAHLLMTEEICLAVSSS
HPLAHTGHISVEQMMNEKFIDLADTPSYAGVFNSIFSKCKKTPQIAYSCNDYILQGKLISLGLGVSFVASVTWTSSSLPE
NISLLHIDDCPHFRSIYYQPLGSFCSENQRIFEHQLEEYFKNLNN
>Mature_285_residues
MELYQLRQFQAAARHKNMTRAASELCIAQPALSKTIHKLEEEFGAQLFIRNKKGLECTRQGEILLEYADRILALSEDATR
AVSESLGDAGDIRLCLRSSAVLVSNVLKDFIHEHPHVSFSISSEPKGCDLLIDSVSSAYDIPDNAHLLMTEEICLAVSSS
HPLAHTGHISVEQMMNEKFIDLADTPSYAGVFNSIFSKCKKTPQIAYSCNDYILQGKLISLGLGVSFVASVTWTSSSLPE
NISLLHIDDCPHFRSIYYQPLGSFCSENQRIFEHQLEEYFKNLNN

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=247, Percent_Identity=28.3400809716599, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1788887, Length=243, Percent_Identity=27.1604938271605, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI157672245, Length=215, Percent_Identity=28.3720930232558, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787530, Length=264, Percent_Identity=25, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI2367136, Length=241, Percent_Identity=23.6514522821577, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787601, Length=226, Percent_Identity=26.1061946902655, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787806, Length=139, Percent_Identity=32.3741007194245, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI87081904, Length=177, Percent_Identity=29.3785310734463, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788706, Length=177, Percent_Identity=28.8135593220339, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31834; Mature: 31834

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELYQLRQFQAAARHKNMTRAASELCIAQPALSKTIHKLEEEFGAQLFIRNKKGLECTRQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCC
GEILLEYADRILALSEDATRAVSESLGDAGDIRLCLRSSAVLVSNVLKDFIHEHPHVSFS
CHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEE
ISSEPKGCDLLIDSVSSAYDIPDNAHLLMTEEICLAVSSSHPLAHTGHISVEQMMNEKFI
ECCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHEECCCCCCCCCCCCCHHHHHHHHCC
DLADTPSYAGVFNSIFSKCKKTPQIAYSCNDYILQGKLISLGLGVSFVASVTWTSSSLPE
CCCCCCCHHHHHHHHHHHHCCCCCEEECCCCEEEECCCEEHHCCHHHHHHHHCCCCCCCC
NISLLHIDDCPHFRSIYYQPLGSFCSENQRIFEHQLEEYFKNLNN
CCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELYQLRQFQAAARHKNMTRAASELCIAQPALSKTIHKLEEEFGAQLFIRNKKGLECTRQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCC
GEILLEYADRILALSEDATRAVSESLGDAGDIRLCLRSSAVLVSNVLKDFIHEHPHVSFS
CHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEE
ISSEPKGCDLLIDSVSSAYDIPDNAHLLMTEEICLAVSSSHPLAHTGHISVEQMMNEKFI
ECCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHEECCCCCCCCCCCCCHHHHHHHHCC
DLADTPSYAGVFNSIFSKCKKTPQIAYSCNDYILQGKLISLGLGVSFVASVTWTSSSLPE
CCCCCCCHHHHHHHHHHHHCCCCCEEECCCCEEEECCCEEHHCCHHHHHHHHCCCCCCCC
NISLLHIDDCPHFRSIYYQPLGSFCSENQRIFEHQLEEYFKNLNN
CCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]