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The map label for this gene is galE [H]

Identifier: 238916117

GI number: 238916117

Start: 179001

End: 180017

Strand: Direct

Name: galE [H]

Synonym: EUBELI_00151

Alternate gene names: 238916117

Gene position: 179001-180017 (Clockwise)

Preceding gene: 238916116

Following gene: 238916118

Centisome position: 8.35

GC content: 38.15

Gene sequence:

>1017_bases
ATGGCAATATTAGTTACAGGCGGAGCAGGCTTTATTGGAAGCCACACAGTAGTAGAACTTCAGAATGCGGGTTATGATGT
TGTAGTAGTTGATAATCTTGTAAATTCAAGCAGAAAGTCTTTAGACAGAGTTGAGAAGATTACAGGAAAGAAAGCCACAT
TTTATGAGGCAGACATTAATGACGCTGCAGCATTAAATGAGATATTTGAGAAAGAAAGTATCGATAGTGTTATACATTTT
GCAGGACTTAAGGCAGTAGGTGAGTCAGTAGCCAAGCCGCTTGAGTATTATATGAATAATATATCCGGTTCACTTACACT
TTTTGATGTTATGAGAAATCATGGTGTTAAGAATATTATATTCTCATCTTCAGCTACAGTTTATGGAGATCCTGCATTTG
TACCTATTACAGAGGAATGCCCTAAGGGTGAGATTACTAATCCTTATGGCAAGACTAAGGGAATGCTTGAGGAGATTCTT
ACAGATATCCAGAAGGCTGACCCGGAATGGAATGTAATTCTTTTAAGATACTTTAACCCAATTGGAGCACATGAGAGCGG
AACAATAGGAGAGAATCCTAACGGAGTTCCTAATAATCTTATGCCATATATAACACAGGTTGCTGTTGGAAAGTTAAAGG
AGCTTGGTGTATTTGGTAATGATTATGATACTCATGATGGAACAGGTGTAAGAGATTATATCCATGTGGTTGACCTTGCA
CTTGGACATGTTAAGGCTATAGAAAAGCTTAATGATAATCCGGGAATTGCAATATATAATCTTGGAACAGGCAATGGATA
TTCAGTGCTTGATATAGTAAAGAATTTTGAGGCTGCTACGGGAATACATATACCATATGTAATTAAGGCAAGAAGACCAG
GTGATATCGCAACATGCTACTGTGACGCAGGTAAGGCAGAGAGAGAGCTTCACTGGAAAGCAGAGCGAGATTTAAAGACT
ATGTGTGCTGATTCATGGAGATGGCAGAAGAATAATCCTAACGGATATGATGATTAA

Upstream 100 bases:

>100_bases
GACAAATAATATCGTAACACAAGACATATAATAAGCCACAGAACGACATGTTATATGAAGTTTTGTGGCTATATTAGTAT
AGAACATAAAGGAGATAATA

Downstream 100 bases:

>100_bases
GGAGTAGACAATGGGTAAGTATTTTGGAACTGACGGATTCAGAGGAGAAGCAAATGTAACTCTTACAGTTGACCATGCAT
TTAAGGTGGGAAGATTCTTA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MAILVTGGAGFIGSHTVVELQNAGYDVVVVDNLVNSSRKSLDRVEKITGKKATFYEADINDAAALNEIFEKESIDSVIHF
AGLKAVGESVAKPLEYYMNNISGSLTLFDVMRNHGVKNIIFSSSATVYGDPAFVPITEECPKGEITNPYGKTKGMLEEIL
TDIQKADPEWNVILLRYFNPIGAHESGTIGENPNGVPNNLMPYITQVAVGKLKELGVFGNDYDTHDGTGVRDYIHVVDLA
LGHVKAIEKLNDNPGIAIYNLGTGNGYSVLDIVKNFEAATGIHIPYVIKARRPGDIATCYCDAGKAERELHWKAERDLKT
MCADSWRWQKNNPNGYDD

Sequences:

>Translated_338_residues
MAILVTGGAGFIGSHTVVELQNAGYDVVVVDNLVNSSRKSLDRVEKITGKKATFYEADINDAAALNEIFEKESIDSVIHF
AGLKAVGESVAKPLEYYMNNISGSLTLFDVMRNHGVKNIIFSSSATVYGDPAFVPITEECPKGEITNPYGKTKGMLEEIL
TDIQKADPEWNVILLRYFNPIGAHESGTIGENPNGVPNNLMPYITQVAVGKLKELGVFGNDYDTHDGTGVRDYIHVVDLA
LGHVKAIEKLNDNPGIAIYNLGTGNGYSVLDIVKNFEAATGIHIPYVIKARRPGDIATCYCDAGKAERELHWKAERDLKT
MCADSWRWQKNNPNGYDD
>Mature_337_residues
AILVTGGAGFIGSHTVVELQNAGYDVVVVDNLVNSSRKSLDRVEKITGKKATFYEADINDAAALNEIFEKESIDSVIHFA
GLKAVGESVAKPLEYYMNNISGSLTLFDVMRNHGVKNIIFSSSATVYGDPAFVPITEECPKGEITNPYGKTKGMLEEILT
DIQKADPEWNVILLRYFNPIGAHESGTIGENPNGVPNNLMPYITQVAVGKLKELGVFGNDYDTHDGTGVRDYIHVVDLAL
GHVKAIEKLNDNPGIAIYNLGTGNGYSVLDIVKNFEAATGIHIPYVIKARRPGDIATCYCDAGKAERELHWKAERDLKTM
CADSWRWQKNNPNGYDD

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=58.2352941176471, Blast_Score=425, Evalue=1e-119,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=58.2352941176471, Blast_Score=425, Evalue=1e-119,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=58.2352941176471, Blast_Score=425, Evalue=1e-119,
Organism=Homo sapiens, GI7657641, Length=275, Percent_Identity=28, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1786974, Length=338, Percent_Identity=57.9881656804734, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1788353, Length=370, Percent_Identity=29.1891891891892, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI48994969, Length=358, Percent_Identity=26.2569832402235, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=56.8115942028986, Blast_Score=402, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=56.4841498559078, Blast_Score=402, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17568069, Length=282, Percent_Identity=25.886524822695, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=52.0348837209302, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI19923002, Length=342, Percent_Identity=58.187134502924, Blast_Score=417, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37015; Mature: 36884

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVTGGAGFIGSHTVVELQNAGYDVVVVDNLVNSSRKSLDRVEKITGKKATFYEADIN
CEEEEECCCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
DAAALNEIFEKESIDSVIHFAGLKAVGESVAKPLEYYMNNISGSLTLFDVMRNHGVKNII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEE
FSSSATVYGDPAFVPITEECPKGEITNPYGKTKGMLEEILTDIQKADPEWNVILLRYFNP
ECCCCEEECCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
IGAHESGTIGENPNGVPNNLMPYITQVAVGKLKELGVFGNDYDTHDGTGVRDYIHVVDLA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
LGHVKAIEKLNDNPGIAIYNLGTGNGYSVLDIVKNFEAATGIHIPYVIKARRPGDIATCY
HHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEE
CDAGKAERELHWKAERDLKTMCADSWRWQKNNPNGYDD
ECCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCC
>Mature Secondary Structure 
AILVTGGAGFIGSHTVVELQNAGYDVVVVDNLVNSSRKSLDRVEKITGKKATFYEADIN
EEEEECCCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
DAAALNEIFEKESIDSVIHFAGLKAVGESVAKPLEYYMNNISGSLTLFDVMRNHGVKNII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEE
FSSSATVYGDPAFVPITEECPKGEITNPYGKTKGMLEEILTDIQKADPEWNVILLRYFNP
ECCCCEEECCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
IGAHESGTIGENPNGVPNNLMPYITQVAVGKLKELGVFGNDYDTHDGTGVRDYIHVVDLA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
LGHVKAIEKLNDNPGIAIYNLGTGNGYSVLDIVKNFEAATGIHIPYVIKARRPGDIATCY
HHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEE
CDAGKAERELHWKAERDLKTMCADSWRWQKNNPNGYDD
ECCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]