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The map label for this gene is arnC [H]

Identifier: 238916116

GI number: 238916116

Start: 178163

End: 178909

Strand: Direct

Name: arnC [H]

Synonym: EUBELI_00150

Alternate gene names: 238916116

Gene position: 178163-178909 (Clockwise)

Preceding gene: 238916115

Following gene: 238916117

Centisome position: 8.31

GC content: 39.22

Gene sequence:

>747_bases
ATGTTATCAGTAGTAATACCAACATTTAATGAAAGCAAGAACATCAGAAATCTTGTAGCACAGATTGATGTTGCTTTGAA
GGGTGTTGATTATGAAATTGTCTTTGTTGATGACAGTAAGGACAATACACCTGATGTAATTACGGAAGTTGCTAAGGAAT
ATCCACAGGTGAGAATGGAACACAGAAAGAATGGTACAGGATTAGCAACTGCTGTTCTCGATGGTTTTAAGCTTGCAAAG
GGAGAATATATGGCATGTATGGATGCTGATTTACAGCACCCGCCAATCGTTCTTAAATATATGTATAAGGCTATGGAAAG
TGGTGCAGATTTCTGTATACCTAGCCGACTTATTCCGGGTGGAGATGATGGCGGACTTAACTGGTACAGAAAGTTCGTAT
CTGGAACAGCAAGAAAGATAGGACAGGTTATGTTGCCTTGCCTTAGAAAGATATCAGATCCTACAAGCGGACTCTTTATG
TTCAGAAGAGAAGTTATTGAGAATGCTGACCTTCAGCCAATCGGATGGAAAATTATGGTTGAGGTTCTTGCAATGGGTAC
ATACAGCAAGGTTGTAGAAATCCCATATAAATTCCAGCAGAGAACAGAAGGTGAATCAAAGCTTTCAGGAAAGGTTACAT
TAGAGTACTTAAAGCAGCTTAAGAATCTCAGAAAGAGATACAATAAGAGCAACAGGTACGAGGTTGAAATATGGTCAACT
GAGCGTATGATGAAAGGCGACAAATAA

Upstream 100 bases:

>100_bases
CAGGCAACCATGGTTGTTACCAGAGTATAAAAAAATGTTTTACTTTGTCGTATATTGATGTATAATGACGAGAGAATTCT
TTTTAAAGGAGAGTATAATA

Downstream 100 bases:

>100_bases
TATCGTAACACAAGACATATAATAAGCCACAGAACGACATGTTATATGAAGTTTTGTGGCTATATTAGTATAGAACATAA
AGGAGATAATAATGGCAATA

Product: dolichol-phosphate mannosyltransferase

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MLSVVIPTFNESKNIRNLVAQIDVALKGVDYEIVFVDDSKDNTPDVITEVAKEYPQVRMEHRKNGTGLATAVLDGFKLAK
GEYMACMDADLQHPPIVLKYMYKAMESGADFCIPSRLIPGGDDGGLNWYRKFVSGTARKIGQVMLPCLRKISDPTSGLFM
FRREVIENADLQPIGWKIMVEVLAMGTYSKVVEIPYKFQQRTEGESKLSGKVTLEYLKQLKNLRKRYNKSNRYEVEIWST
ERMMKGDK

Sequences:

>Translated_248_residues
MLSVVIPTFNESKNIRNLVAQIDVALKGVDYEIVFVDDSKDNTPDVITEVAKEYPQVRMEHRKNGTGLATAVLDGFKLAK
GEYMACMDADLQHPPIVLKYMYKAMESGADFCIPSRLIPGGDDGGLNWYRKFVSGTARKIGQVMLPCLRKISDPTSGLFM
FRREVIENADLQPIGWKIMVEVLAMGTYSKVVEIPYKFQQRTEGESKLSGKVTLEYLKQLKNLRKRYNKSNRYEVEIWST
ERMMKGDK
>Mature_248_residues
MLSVVIPTFNESKNIRNLVAQIDVALKGVDYEIVFVDDSKDNTPDVITEVAKEYPQVRMEHRKNGTGLATAVLDGFKLAK
GEYMACMDADLQHPPIVLKYMYKAMESGADFCIPSRLIPGGDDGGLNWYRKFVSGTARKIGQVMLPCLRKISDPTSGLFM
FRREVIENADLQPIGWKIMVEVLAMGTYSKVVEIPYKFQQRTEGESKLSGKVTLEYLKQLKNLRKRYNKSNRYEVEIWST
ERMMKGDK

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=231, Percent_Identity=32.4675324675325, Blast_Score=99, Evalue=3e-21,
Organism=Escherichia coli, GI1788588, Length=212, Percent_Identity=26.8867924528302, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788692, Length=218, Percent_Identity=29.3577981651376, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71999402, Length=234, Percent_Identity=30.3418803418803, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6325441, Length=234, Percent_Identity=38.8888888888889, Blast_Score=147, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24585265, Length=228, Percent_Identity=29.8245614035088, Blast_Score=93, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022857
- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.7.8.30 [H]

Molecular weight: Translated: 28235; Mature: 28235

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVVIPTFNESKNIRNLVAQIDVALKGVDYEIVFVDDSKDNTPDVITEVAKEYPQVRME
CCEEEECCCCCCHHHHHHHHHHHHHEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
HRKNGTGLATAVLDGFKLAKGEYMACMDADLQHPPIVLKYMYKAMESGADFCIPSRLIPG
HCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
GDDGGLNWYRKFVSGTARKIGQVMLPCLRKISDPTSGLFMFRREVIENADLQPIGWKIMV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHH
EVLAMGTYSKVVEIPYKFQQRTEGESKLSGKVTLEYLKQLKNLRKRYNKSNRYEVEIWST
HHHHHCCHHHHHHCCHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
ERMMKGDK
HHHCCCCC
>Mature Secondary Structure
MLSVVIPTFNESKNIRNLVAQIDVALKGVDYEIVFVDDSKDNTPDVITEVAKEYPQVRME
CCEEEECCCCCCHHHHHHHHHHHHHEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
HRKNGTGLATAVLDGFKLAKGEYMACMDADLQHPPIVLKYMYKAMESGADFCIPSRLIPG
HCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
GDDGGLNWYRKFVSGTARKIGQVMLPCLRKISDPTSGLFMFRREVIENADLQPIGWKIMV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHH
EVLAMGTYSKVVEIPYKFQQRTEGESKLSGKVTLEYLKQLKNLRKRYNKSNRYEVEIWST
HHHHHCCHHHHHHCCHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
ERMMKGDK
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA