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The map label for this gene is lysA [H]

Identifier: 238916082

GI number: 238916082

Start: 130030

End: 131268

Strand: Direct

Name: lysA [H]

Synonym: EUBELI_00115

Alternate gene names: 238916082

Gene position: 130030-131268 (Clockwise)

Preceding gene: 238916081

Following gene: 238916083

Centisome position: 6.06

GC content: 38.58

Gene sequence:

>1239_bases
ATGGTAGGAGTTAATGAATTAAAAGAGATTGCCATAAAATGTGGAACACCATCGTATATATTTGATACAGATGAGCTATG
TGCAAGGATTGATGCCATGCAGCAGATTTTGGGATGCGGTGTTACAGTGTGTTATGCAATGAAGGCTAATCCGTTTCTTA
TCAGCGTGCTTGACAAGAAGCTTGACAAATTCGAGGTATGTTCTCCGGGTGAATTTGCGATATGCGAAAAAGAAGGCATA
AACAGGGAGAAGATTGTACTTTCGGGTGTTAATAAGGAAAAGAAAGATATTCTCTACACAATGAAGACAGGTGCTGTTGG
AATCTACACTGTGGAATCGCTTAACCAGCTTGAACTTATCAATTCATGTGCAGTTGAGTGTGGCATTAAGGTTAAGGTTC
TTATAAGAGTTACCAGCGGCAACCAGTTCGGTATTAATGAGCGTCAGGTATATGAGATTGCAGACAGAAAGGATGAACTT
AAGGGAATTATCCTTGAGGGAATCCAGTGCTATTCGGGAACCCAGAAGAAGAAATTAAGCCAGATAGAAGCTGAGGTAGT
ATGGTTACAGGCAATAGCACATACATGTGAGGCTGAACATGGTGTTGAGCTTAAAGAGATTGAATATGGTCCTGGCCTGT
CAGTTGATTACTTTGTTACAGACAAATGTGATGCCATGAATACTGATTTTGACGAGCTTAAAGAGTTTGCTGTGATGATT
AAAGAAATGTCCGAAAAGTTCAATGTTACTCTTGAGATGGGACGATATATTGCAGCTACCTGTGGAATACTTATAAGCAG
AATTGCTGATATGAAGATGAATGACACAACAAGATACGCAATTATTGACAGTGGAATTAATCATATTAATTATTATGGAC
AGGCTATGGCTATGAAGAAACCAAGATGTGAATTCATTCCAATGGAGTACACAGAAGGGTTTGCTGATGGCGTAGATCAT
GAGGTGGAAGTGTATTCACAGGGAGTGCAGCCGTATAATATATGTGGTTCATTATGTACAGTAGGAGATGTAATTGTTAA
GAATCTTGAATTAAAGGATGCTAAGATTGGTGATATGATAGCATTTTATAATATTGGAGCGTATTCTGTTACAGAGGGAA
TATATCTGTTCCTGAGCCGCCGAATGCCTGCAATTGTGATGTATTCAATGAAGAATGGCTACAGGATTGTTAGAAATCCA
GTGGACACTTTTTTAATAAACAGTGTTAGTACACAATAA

Upstream 100 bases:

>100_bases
CCAAATGTGCTCGTTAAGGTTGAAACAATGCCGATTACTAAGAATGGTAAAATTGACAGAAAAGAACTTATGAAGATATA
TAAAGAACAGGAGGCATAGG

Downstream 100 bases:

>100_bases
TTTTACAATTTTGTAACAAAATATGATTGACTATATGTGAATGAGAAGATAGAATGTTTTCTGTTCACAGATGTGTGATT
AATAATTTTTTTGCGAGGTT

Product: diaminopimelate decarboxylase

Products: NA

Alternate protein names: DAP decarboxylase [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MVGVNELKEIAIKCGTPSYIFDTDELCARIDAMQQILGCGVTVCYAMKANPFLISVLDKKLDKFEVCSPGEFAICEKEGI
NREKIVLSGVNKEKKDILYTMKTGAVGIYTVESLNQLELINSCAVECGIKVKVLIRVTSGNQFGINERQVYEIADRKDEL
KGIILEGIQCYSGTQKKKLSQIEAEVVWLQAIAHTCEAEHGVELKEIEYGPGLSVDYFVTDKCDAMNTDFDELKEFAVMI
KEMSEKFNVTLEMGRYIAATCGILISRIADMKMNDTTRYAIIDSGINHINYYGQAMAMKKPRCEFIPMEYTEGFADGVDH
EVEVYSQGVQPYNICGSLCTVGDVIVKNLELKDAKIGDMIAFYNIGAYSVTEGIYLFLSRRMPAIVMYSMKNGYRIVRNP
VDTFLINSVSTQ

Sequences:

>Translated_412_residues
MVGVNELKEIAIKCGTPSYIFDTDELCARIDAMQQILGCGVTVCYAMKANPFLISVLDKKLDKFEVCSPGEFAICEKEGI
NREKIVLSGVNKEKKDILYTMKTGAVGIYTVESLNQLELINSCAVECGIKVKVLIRVTSGNQFGINERQVYEIADRKDEL
KGIILEGIQCYSGTQKKKLSQIEAEVVWLQAIAHTCEAEHGVELKEIEYGPGLSVDYFVTDKCDAMNTDFDELKEFAVMI
KEMSEKFNVTLEMGRYIAATCGILISRIADMKMNDTTRYAIIDSGINHINYYGQAMAMKKPRCEFIPMEYTEGFADGVDH
EVEVYSQGVQPYNICGSLCTVGDVIVKNLELKDAKIGDMIAFYNIGAYSVTEGIYLFLSRRMPAIVMYSMKNGYRIVRNP
VDTFLINSVSTQ
>Mature_412_residues
MVGVNELKEIAIKCGTPSYIFDTDELCARIDAMQQILGCGVTVCYAMKANPFLISVLDKKLDKFEVCSPGEFAICEKEGI
NREKIVLSGVNKEKKDILYTMKTGAVGIYTVESLNQLELINSCAVECGIKVKVLIRVTSGNQFGINERQVYEIADRKDEL
KGIILEGIQCYSGTQKKKLSQIEAEVVWLQAIAHTCEAEHGVELKEIEYGPGLSVDYFVTDKCDAMNTDFDELKEFAVMI
KEMSEKFNVTLEMGRYIAATCGILISRIADMKMNDTTRYAIIDSGINHINYYGQAMAMKKPRCEFIPMEYTEGFADGVDH
EVEVYSQGVQPYNICGSLCTVGDVIVKNLELKDAKIGDMIAFYNIGAYSVTEGIYLFLSRRMPAIVMYSMKNGYRIVRNP
VDTFLINSVSTQ

Specific function: Lysine biosynthesis; last step. [C]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002986
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.20 [H]

Molecular weight: Translated: 46063; Mature: 46063

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGVNELKEIAIKCGTPSYIFDTDELCARIDAMQQILGCGVTVCYAMKANPFLISVLDKK
CCCHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEHHHHC
LDKFEVCSPGEFAICEKEGINREKIVLSGVNKEKKDILYTMKTGAVGIYTVESLNQLELI
CCCCCCCCCCCEEEECCCCCCCCEEEEECCCCCCHHEEEEEECCCEEEEEECCCHHHHHH
NSCAVECGIKVKVLIRVTSGNQFGINERQVYEIADRKDELKGIILEGIQCYSGTQKKKLS
HHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHH
QIEAEVVWLQAIAHTCEAEHGVELKEIEYGPGLSVDYFVTDKCDAMNTDFDELKEFAVMI
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHH
KEMSEKFNVTLEMGRYIAATCGILISRIADMKMNDTTRYAIIDSGINHINYYGQAMAMKK
HHHHHHHCEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHCCCC
PRCEFIPMEYTEGFADGVDHEVEVYSQGVQPYNICGSLCTVGDVIVKNLELKDAKIGDMI
CCCCEECCHHHCCHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
AFYNIGAYSVTEGIYLFLSRRMPAIVMYSMKNGYRIVRNPVDTFLINSVSTQ
EEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCHHHHHHHCCCCC
>Mature Secondary Structure
MVGVNELKEIAIKCGTPSYIFDTDELCARIDAMQQILGCGVTVCYAMKANPFLISVLDKK
CCCHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEHHHHC
LDKFEVCSPGEFAICEKEGINREKIVLSGVNKEKKDILYTMKTGAVGIYTVESLNQLELI
CCCCCCCCCCCEEEECCCCCCCCEEEEECCCCCCHHEEEEEECCCEEEEEECCCHHHHHH
NSCAVECGIKVKVLIRVTSGNQFGINERQVYEIADRKDELKGIILEGIQCYSGTQKKKLS
HHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHH
QIEAEVVWLQAIAHTCEAEHGVELKEIEYGPGLSVDYFVTDKCDAMNTDFDELKEFAVMI
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHH
KEMSEKFNVTLEMGRYIAATCGILISRIADMKMNDTTRYAIIDSGINHINYYGQAMAMKK
HHHHHHHCEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHCCCC
PRCEFIPMEYTEGFADGVDHEVEVYSQGVQPYNICGSLCTVGDVIVKNLELKDAKIGDMI
CCCCEECCHHHCCHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
AFYNIGAYSVTEGIYLFLSRRMPAIVMYSMKNGYRIVRNPVDTFLINSVSTQ
EEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA