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The map label for this gene is atpA [H]

Identifier: 238897241

GI number: 238897241

Start: 5241058

End: 5242599

Strand: Reverse

Name: atpA [H]

Synonym: KP1_5516

Alternate gene names: 238897241

Gene position: 5242599-5241058 (Counterclockwise)

Preceding gene: 238897242

Following gene: 238897240

Centisome position: 99.89

GC content: 55.45

Gene sequence:

>1542_bases
ATGCAACTGAATTCCACCGAAATCAGCGAACTGATCAAGCAGCGCATTGCTCAGTTCAATGTTGTGAGCGAAGCTCATAA
CGAAGGTACTATTGTTTCTGTAAGTGACGGTGTTATCCGCATCCACGGCCTTGCCGAATGTATGCAGGGCGAGATGATCT
CCCTGCCGGGTAACCGTTACGCTATCGCACTGAACCTGGAGCGCGACTCCGTAGGTGCGGTGGTAATGGGTCCGTACGCT
GACCTCGCCGAAGGCATGAAGGTGAAATGTACTGGCCGTATCCTGGAAGTTCCGGTAGGCCGTGGCCTGCTGGGCCGCGT
GGTTAACACCCTGGGCGCGCCAATTGATGGTAAAGGTCCGCTGGAAAACGACGGTTTCTCCGCCGTTGAAGCGATCGCGC
CGGGCGTAATCGAACGTCAGTCCGTCGATCAGCCGGTACAGACCGGTTACAAATCCGTTGACGCCATGATCCCAATCGGT
CGTGGTCAGCGTGAACTGATCATCGGCGACCGTCAGACCGGTAAAACTGCGCTGGCTATCGATGCCATCATCAACCAGCG
TGATTCCGGCATCAAGTGCGTCTATGTCGCTATCGGTCAGAAAGCGTCCACCATCTCTAACGTGGTGCGTAAACTGGAAG
AGCACGGCGCGCTGGCTAACACCATCGTAGTGGTAGCGACTGCATCTGAATCTGCTGCACTGCAATACCTGGCGCCATAC
GCTGGTTGCGCAATGGGCGAATACTTCCGCGACCGCGGTGAAGATGCGCTGATCGTTTACGATGATCTGTCTAAACAGGC
TGTTGCTTATCGCCAGATCTCCCTGCTGCTCCGTCGTCCGCCTGGACGTGAAGCGTTCCCGGGCGACGTATTCTACCTCC
ACTCTCGTCTGCTGGAGCGTGCTGCGCGTGTTAACGCCGAATACGTTGAAGCCTTCACCAAAGGTGAAGTGAAAGGGAAA
ACCGGTTCTCTGACCGCGCTGCCGATTATCGAAACGCAGGCGGGTGACGTTTCCGCATTCGTTCCGACCAACGTAATCTC
TATTACCGATGGTCAGATCTTCCTGGAAACCAACCTGTTTAACGCCGGTATTCGTCCTGCGGTTAACCCGGGTATCTCCG
TATCCCGTGTTGGTGGTGCAGCGCAGACCAAGATCATGAAGAAACTGTCCGGTGGTATCCGTACCGCGCTGGCGCAGTAT
CGTGAACTGGCGGCGTTCTCCCAGTTTGCATCCGACCTTGACGATGCAACCCGCAAACAGCTGGACCACGGTCAGAAAGT
GACCGAGCTGCTGAAACAGAAACAGTATGCGCCGATGTCCGTCGCGCAGCAGTCTCTGGTTCTGTTCGCAGCAGAACGTG
GTTACCTGGCTGATGTAGAACTGGCGAAAATCGGTAGCTTCGAAGCCGCTCTGCTGGCTTACGTCGACCGTGATCACGCT
CCGCTGATGCAAGAGATTAACCAGTCCGGTGGCTATAACGACGAAATCGAAGGCAAGCTGAAAGGCATCCTCGATTCCTT
CAAAGCAACCCAGTCCTGGTAA

Upstream 100 bases:

>100_bases
AGGTATTATCATCCGTGCGGGTGATATGGTCATTGATGGCAGCGTACGCGGCCGTCTTGAGCGCCTTGCAGACGTCTTGC
AGTCTTAAGGGGACTGGAGC

Downstream 100 bases:

>100_bases
CGTCTGGCGGTCTGTCTTAGGGCAGGCCGCAAGGCATTGAGGAGAAGCTCATGGCCGGCGCAAAAGAGATACGTAGTAAG
ATCGCAAGCGTCCAGAACAC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLAECMQGEMISLPGNRYAIALNLERDSVGAVVMGPYA
DLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPLENDGFSAVEAIAPGVIERQSVDQPVQTGYKSVDAMIPIG
RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCVYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPY
AGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQY
RELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELAKIGSFEAALLAYVDRDHA
PLMQEINQSGGYNDEIEGKLKGILDSFKATQSW

Sequences:

>Translated_513_residues
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLAECMQGEMISLPGNRYAIALNLERDSVGAVVMGPYA
DLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPLENDGFSAVEAIAPGVIERQSVDQPVQTGYKSVDAMIPIG
RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCVYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPY
AGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQY
RELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELAKIGSFEAALLAYVDRDHA
PLMQEINQSGGYNDEIEGKLKGILDSFKATQSW
>Mature_513_residues
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLAECMQGEMISLPGNRYAIALNLERDSVGAVVMGPYA
DLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPLENDGFSAVEAIAPGVIERQSVDQPVQTGYKSVDAMIPIG
RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCVYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPY
AGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQY
RELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELAKIGSFEAALLAYVDRDHA
PLMQEINQSGGYNDEIEGKLKGILDSFKATQSW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=513, Percent_Identity=55.5555555555556, Blast_Score=555, Evalue=1e-158,
Organism=Homo sapiens, GI4757810, Length=513, Percent_Identity=55.5555555555556, Blast_Score=555, Evalue=1e-158,
Organism=Homo sapiens, GI19913426, Length=323, Percent_Identity=27.8637770897833, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI19913428, Length=314, Percent_Identity=28.6624203821656, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI32189394, Length=435, Percent_Identity=24.5977011494253, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI19913424, Length=259, Percent_Identity=27.7992277992278, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=98.2456140350877, Blast_Score=1033, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=340, Percent_Identity=26.4705882352941, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI1788251, Length=345, Percent_Identity=24.9275362318841, Blast_Score=100, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=515, Percent_Identity=54.3689320388349, Blast_Score=551, Evalue=1e-157,
Organism=Caenorhabditis elegans, GI71988080, Length=515, Percent_Identity=54.3689320388349, Blast_Score=551, Evalue=1e-157,
Organism=Caenorhabditis elegans, GI71988074, Length=515, Percent_Identity=50.6796116504854, Blast_Score=504, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI17510931, Length=368, Percent_Identity=26.0869565217391, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17570191, Length=313, Percent_Identity=27.7955271565495, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=448, Percent_Identity=24.7767857142857, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17509265, Length=47, Percent_Identity=65.9574468085106, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=254, Percent_Identity=27.1653543307087, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=513, Percent_Identity=53.2163742690059, Blast_Score=550, Evalue=1e-157,
Organism=Saccharomyces cerevisiae, GI6322581, Length=474, Percent_Identity=24.6835443037975, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6319603, Length=370, Percent_Identity=25.4054054054054, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24658560, Length=514, Percent_Identity=54.2801556420233, Blast_Score=545, Evalue=1e-155,
Organism=Drosophila melanogaster, GI281361666, Length=313, Percent_Identity=27.4760383386581, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24646341, Length=313, Percent_Identity=27.4760383386581, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI17136796, Length=313, Percent_Identity=27.4760383386581, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24638766, Length=434, Percent_Identity=25.3456221198157, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI28574560, Length=321, Percent_Identity=25.5451713395639, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24583992, Length=259, Percent_Identity=27.4131274131274, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24583988, Length=259, Percent_Identity=27.4131274131274, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24583986, Length=259, Percent_Identity=27.4131274131274, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24583984, Length=259, Percent_Identity=27.4131274131274, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55170; Mature: 55170

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLAECMQGEMISLPGNRY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEHHHHHCCCEEECCCCEE
AIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGP
EEEEEECCCCCCEEEECCCHHHHCCCEEEECCEEEECCCCCCHHHHHHHHHCCCCCCCCC
LENDGFSAVEAIAPGVIERQSVDQPVQTGYKSVDAMIPIGRGQRELIIGDRQTGKTALAI
CCCCCHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHEEECCCCCEEEEEECCCCCCHHEEH
DAIINQRDSGIKCVYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPY
HHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHH
AGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLER
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLF
HHHCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECCC
NAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQ
CCCCCCCCCCCCEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELAKIGSFEAALLAYVDRDHA
HHCCHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCEECCHHHHCCCHHHHHHHHHCCCCC
PLMQEINQSGGYNDEIEGKLKGILDSFKATQSW
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLAECMQGEMISLPGNRY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEHHHHHCCCEEECCCCEE
AIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGP
EEEEEECCCCCCEEEECCCHHHHCCCEEEECCEEEECCCCCCHHHHHHHHHCCCCCCCCC
LENDGFSAVEAIAPGVIERQSVDQPVQTGYKSVDAMIPIGRGQRELIIGDRQTGKTALAI
CCCCCHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHEEECCCCCEEEEEECCCCCCHHEEH
DAIINQRDSGIKCVYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPY
HHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHH
AGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLER
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLF
HHHCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECCC
NAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQ
CCCCCCCCCCCCEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELAKIGSFEAALLAYVDRDHA
HHCCHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCEECCHHHHCCCHHHHHHHHHCCCCC
PLMQEINQSGGYNDEIEGKLKGILDSFKATQSW
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA