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The map label for this gene is yieG [H]

Identifier: 238897223

GI number: 238897223

Start: 5222924

End: 5224261

Strand: Reverse

Name: yieG [H]

Synonym: KP1_5494

Alternate gene names: 238897223

Gene position: 5224261-5222924 (Counterclockwise)

Preceding gene: 238897225

Following gene: 238897213

Centisome position: 99.54

GC content: 59.34

Gene sequence:

>1338_bases
ATGAGTCAACAACAAACCAGCCAGTCTTCTGGCCAGGGTCTGCTGGAGCGCGTATTTAAGCTGCGCGAGCACGGCACCAC
GGTGCGCACCGAAGCCATCGCCGGTTTCACCACGTTCCTGACGATGGTGTATATCGTTTTTGTTAACCCACAAATTCTTG
GCGTAGCGGGCATGGATACCAGCGCCGTGTTTGTGACCACCTGTCTGATTGCCGCTTTCGGCAGTATCCTGATGGGTCTG
TTCGCGAACCTGCCGGTCGCCCTGGCGCCGGCGATGGGCCTGAACGCCTTTTTCGCCTTTGTGGTGGTGCAGGCGATGGG
GCTGCCGTGGCAGGTGGGCATGGGCGCCATCTTCTGGGGCGCCGTGGGCCTGCTGCTGCTGACCATCTTCCGCGTACGTT
ACTGGATGATCGCCAATATTCCGCTTAGCCTGCGTGTAGGTATCACCAGCGGTATCGGCCTGTTTATCGGCATGATGGGC
CTGAAAAACGCCGGGGTGATTGTCGCCAATCCGGAAACGCTGGTCAGCATTGGTCATTTGACTTCCCACAGCGTACTGCT
GGGCGTGCTGGGCTTCTTTATCATCGCGATTCTGGCGTCGCGCAACATTCACGCCGCGGTACTGGTCTCTATCGTTGTGA
CCACCCTGCTGGGCTGGATGCTGGGCGACGTGCATTACACCGGGATCGTCTCGGCGCCGCCGAGCGTGGCTTCGGTGATT
GGTCAGGTCGATCTGGCGGGCTCCCTGAACCTGGGCCTGGCCGGCGTGATCTTCTCCTTTATGCTGGTCAACCTGTTTGA
CTCCTCCGGGACGCTGATTGGCGTGACGGATAAAGCGGGTCTCGCGGATGCCAACGGTAAATTCCCGCGCATGAAGCAAG
CGCTGTTTGTCGATAGCGTCTCGTCGGTGGCGGGCTCCTTCATCGGTACCTCGTCGGTGACGGCCTATATCGAATCTTCT
TCCGGCGTTTCCGTGGGCGGGCGTACCGGCCTGACCGCCGTTGTCGTTGGTATCCTGTTCCTGCTGGTTATTTTCCTCTC
TCCGCTGGCGGGGATGGTTCCTGGCTATGCCGCCGCGGGCGCGCTGATATACGTCGGCGTGCTGATGACCTCCAGCCTCG
CGCGCGTGAAGTGGAGCGACCTGACCGAGGCGGTGCCTGCGTTCATCACCGCAGTGATGATGCCGTTTAGCTTCTCGATC
ACCGAAGGTATCGCCCTGGGCTTTATCTCTTACTGCGTGATGAAGATCGGTACCGGCCGGCTGCGCGAGCTCAGCCCGTG
TGTGATTATCGTTTCGCTGCTGTTCGTGCTGAAAATTGTCTTTATCGATGCACATTAA

Upstream 100 bases:

>100_bases
AGCAAAATAAATGAAAAAAATTACCATACAACCGCGCCCGGTGCCGTAATTTGGTATAGGATAGCCTCGAATTTTCCCTC
CTTACGTTCGGAAACCGATA

Downstream 100 bases:

>100_bases
TCCGCACGCATGATGAAAAAGCCCGGCATCGCTGCCGGGCTTTTTTTATGCTTTAACCCGCCGAATATAGTCGCCGAAAG
CGGTCAGTTGGCCGCGCAGA

Product: putative membrane / transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSQQQTSQSSGQGLLERVFKLREHGTTVRTEAIAGFTTFLTMVYIVFVNPQILGVAGMDTSAVFVTTCLIAAFGSILMGL
FANLPVALAPAMGLNAFFAFVVVQAMGLPWQVGMGAIFWGAVGLLLLTIFRVRYWMIANIPLSLRVGITSGIGLFIGMMG
LKNAGVIVANPETLVSIGHLTSHSVLLGVLGFFIIAILASRNIHAAVLVSIVVTTLLGWMLGDVHYTGIVSAPPSVASVI
GQVDLAGSLNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADANGKFPRMKQALFVDSVSSVAGSFIGTSSVTAYIESS
SGVSVGGRTGLTAVVVGILFLLVIFLSPLAGMVPGYAAAGALIYVGVLMTSSLARVKWSDLTEAVPAFITAVMMPFSFSI
TEGIALGFISYCVMKIGTGRLRELSPCVIIVSLLFVLKIVFIDAH

Sequences:

>Translated_445_residues
MSQQQTSQSSGQGLLERVFKLREHGTTVRTEAIAGFTTFLTMVYIVFVNPQILGVAGMDTSAVFVTTCLIAAFGSILMGL
FANLPVALAPAMGLNAFFAFVVVQAMGLPWQVGMGAIFWGAVGLLLLTIFRVRYWMIANIPLSLRVGITSGIGLFIGMMG
LKNAGVIVANPETLVSIGHLTSHSVLLGVLGFFIIAILASRNIHAAVLVSIVVTTLLGWMLGDVHYTGIVSAPPSVASVI
GQVDLAGSLNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADANGKFPRMKQALFVDSVSSVAGSFIGTSSVTAYIESS
SGVSVGGRTGLTAVVVGILFLLVIFLSPLAGMVPGYAAAGALIYVGVLMTSSLARVKWSDLTEAVPAFITAVMMPFSFSI
TEGIALGFISYCVMKIGTGRLRELSPCVIIVSLLFVLKIVFIDAH
>Mature_444_residues
SQQQTSQSSGQGLLERVFKLREHGTTVRTEAIAGFTTFLTMVYIVFVNPQILGVAGMDTSAVFVTTCLIAAFGSILMGLF
ANLPVALAPAMGLNAFFAFVVVQAMGLPWQVGMGAIFWGAVGLLLLTIFRVRYWMIANIPLSLRVGITSGIGLFIGMMGL
KNAGVIVANPETLVSIGHLTSHSVLLGVLGFFIIAILASRNIHAAVLVSIVVTTLLGWMLGDVHYTGIVSAPPSVASVIG
QVDLAGSLNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADANGKFPRMKQALFVDSVSSVAGSFIGTSSVTAYIESSS
GVSVGGRTGLTAVVVGILFLLVIFLSPLAGMVPGYAAAGALIYVGVLMTSSLARVKWSDLTEAVPAFITAVMMPFSFSIT
EGIALGFISYCVMKIGTGRLRELSPCVIIVSLLFVLKIVFIDAH

Specific function: High-affinity uptake of adenine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=445, Percent_Identity=93.2584269662921, Blast_Score=807, Evalue=0.0,
Organism=Escherichia coli, GI87082309, Length=444, Percent_Identity=74.5495495495496, Blast_Score=666, Evalue=0.0,
Organism=Escherichia coli, GI1790499, Length=440, Percent_Identity=36.1363636363636, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI48994909, Length=436, Percent_Identity=37.3853211009174, Blast_Score=261, Evalue=6e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46518; Mature: 46387

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS00267 TACHYKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQQTSQSSGQGLLERVFKLREHGTTVRTEAIAGFTTFLTMVYIVFVNPQILGVAGMDT
CCCCCCCCCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
SAVFVTTCLIAAFGSILMGLFANLPVALAPAMGLNAFFAFVVVQAMGLPWQVGMGAIFWG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AVGLLLLTIFRVRYWMIANIPLSLRVGITSGIGLFIGMMGLKNAGVIVANPETLVSIGHL
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHH
TSHSVLLGVLGFFIIAILASRNIHAAVLVSIVVTTLLGWMLGDVHYTGIVSAPPSVASVI
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHH
GQVDLAGSLNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADANGKFPRMKQALFVDSV
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHH
SSVAGSFIGTSSVTAYIESSSGVSVGGRTGLTAVVVGILFLLVIFLSPLAGMVPGYAAAG
HHHHHHHCCCCHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ALIYVGVLMTSSLARVKWSDLTEAVPAFITAVMMPFSFSITEGIALGFISYCVMKIGTGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
LRELSPCVIIVSLLFVLKIVFIDAH
HHHCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQQQTSQSSGQGLLERVFKLREHGTTVRTEAIAGFTTFLTMVYIVFVNPQILGVAGMDT
CCCCCCCCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
SAVFVTTCLIAAFGSILMGLFANLPVALAPAMGLNAFFAFVVVQAMGLPWQVGMGAIFWG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AVGLLLLTIFRVRYWMIANIPLSLRVGITSGIGLFIGMMGLKNAGVIVANPETLVSIGHL
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHH
TSHSVLLGVLGFFIIAILASRNIHAAVLVSIVVTTLLGWMLGDVHYTGIVSAPPSVASVI
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHH
GQVDLAGSLNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADANGKFPRMKQALFVDSV
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHH
SSVAGSFIGTSSVTAYIESSSGVSVGGRTGLTAVVVGILFLLVIFLSPLAGMVPGYAAAG
HHHHHHHCCCCHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ALIYVGVLMTSSLARVKWSDLTEAVPAFITAVMMPFSFSITEGIALGFISYCVMKIGTGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
LRELSPCVIIVSLLFVLKIVFIDAH
HHHCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]