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The map label for this gene is yieK [H]

Identifier: 238897225

GI number: 238897225

Start: 5225176

End: 5225895

Strand: Reverse

Name: yieK [H]

Synonym: KP1_5497

Alternate gene names: 238897225

Gene position: 5225895-5225176 (Counterclockwise)

Preceding gene: 238897226

Following gene: 238897223

Centisome position: 99.57

GC content: 55.14

Gene sequence:

>720_bases
ATGAAAATGATTGTGACCGAAGATTATGAAGAGATGAGCCTGGTCGCCAGCCATCATGTTCTGGGCTATATCACGGCGCC
GCGGCGGGTGAATCTGGCGGTGACGGCGGGGAGCACGCCAAAGCGGATGTATGAGCATTTGACCGCCGCCGTGAAAGGCA
AAGCATTCTATGATCGGGTGCACTATTACAACTTCGATGAGATCCCTTTTCGCGGCCAGTCGCGAGAAGGCGTCACGATA
TCTAATTTGCGCCAGCTGTTTTTTACCCCGGCGCAGATCAAAGAAGAGAACATTCACAAGCTGACGCTGGACAACGCCGC
TCAGCACGATCGCCAGCTGGAAGAGGCTGGCGGTCTGGATCTGATGGTGCTGGGGCTGGGGGCCGACGGCCATTTTTGCG
GCAACCTGCCGAATACCACCCGCTTTCATGATCAGACGGTCGAAGTGCCGATTCATGGGGAAATGATTGCTCTTATCGCT
AACAGCGAGATGGGCGGGGATATCTCGGCAGTACCAAACAGCTATGTCACCATGGGGCCGAGAAGCGTGATGGCGGCGAA
AAATTTATTGCTAATTGTCAGCGGTGCGGCAAAAGCGCACGCGTTAAAGCAAGTGGTGGAAGGTCCGGTCAGCGTGCAGG
TGCCGGCTTCAGTGCTCAAATTGCACCCTTCACTGGTGATTATTGCCGATAAAGCGGCGGCGGCGGAGTTGCAGCAATAA

Upstream 100 bases:

>100_bases
ACGTCTGGCGCCCGGCCTACGCCGAGTTTGTGCAAAAACTGTTTAAATAACCTTTAGGGGGGCCTTCAGCCCCCGTTTTG
TGCTTGTGAAGGACGACAAG

Downstream 100 bases:

>100_bases
AAAGCTGCTAGTTCTATTCCCCGCTTACGCAGATGCATAGCGGGGGGTCATCGATGCCAACGTGCCGCTCACCAGGCCCT
TAACGCGTGATATCCCAGCC

Product: putative 6-phosphogluconolactonase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MKMIVTEDYEEMSLVASHHVLGYITAPRRVNLAVTAGSTPKRMYEHLTAAVKGKAFYDRVHYYNFDEIPFRGQSREGVTI
SNLRQLFFTPAQIKEENIHKLTLDNAAQHDRQLEEAGGLDLMVLGLGADGHFCGNLPNTTRFHDQTVEVPIHGEMIALIA
NSEMGGDISAVPNSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASVLKLHPSLVIIADKAAAAELQQ

Sequences:

>Translated_239_residues
MKMIVTEDYEEMSLVASHHVLGYITAPRRVNLAVTAGSTPKRMYEHLTAAVKGKAFYDRVHYYNFDEIPFRGQSREGVTI
SNLRQLFFTPAQIKEENIHKLTLDNAAQHDRQLEEAGGLDLMVLGLGADGHFCGNLPNTTRFHDQTVEVPIHGEMIALIA
NSEMGGDISAVPNSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASVLKLHPSLVIIADKAAAAELQQ
>Mature_239_residues
MKMIVTEDYEEMSLVASHHVLGYITAPRRVNLAVTAGSTPKRMYEHLTAAVKGKAFYDRVHYYNFDEIPFRGQSREGVTI
SNLRQLFFTPAQIKEENIHKLTLDNAAQHDRQLEEAGGLDLMVLGLGADGHFCGNLPNTTRFHDQTVEVPIHGEMIALIA
NSEMGGDISAVPNSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASVLKLHPSLVIIADKAAAAELQQ

Specific function: Unknown

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI19923881, Length=252, Percent_Identity=28.1746031746032, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI13027378, Length=251, Percent_Identity=29.0836653386454, Blast_Score=91, Evalue=9e-19,
Organism=Escherichia coli, GI48994958, Length=228, Percent_Identity=71.0526315789474, Blast_Score=355, Evalue=1e-99,
Organism=Escherichia coli, GI1786893, Length=252, Percent_Identity=28.968253968254, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789530, Length=231, Percent_Identity=24.2424242424242, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17554876, Length=250, Percent_Identity=30, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24581960, Length=252, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI19920764, Length=252, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: NA

Molecular weight: Translated: 26022; Mature: 26022

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMIVTEDYEEMSLVASHHVLGYITAPRRVNLAVTAGSTPKRMYEHLTAAVKGKAFYDRV
CCEEEECCHHHHHHHHHCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHH
HYYNFDEIPFRGQSREGVTISNLRQLFFTPAQIKEENIHKLTLDNAAQHDRQLEEAGGLD
EECCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHCCCCCEEEEECCHHHHHHHHHHHCCCE
LMVLGLGADGHFCGNLPNTTRFHDQTVEVPIHGEMIALIANSEMGGDISAVPNSYVTMGP
EEEEEECCCCCEECCCCCCCEECCCEEEEEECCCEEEEEECCCCCCCEECCCCCEEEECC
RSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASVLKLHPSLVIIADKAAAAELQQ
HHHHHHCCEEEEEECCHHHHHHHHHHCCCCEEEECHHHHHCCCCEEEEECCHHHHHCCC
>Mature Secondary Structure
MKMIVTEDYEEMSLVASHHVLGYITAPRRVNLAVTAGSTPKRMYEHLTAAVKGKAFYDRV
CCEEEECCHHHHHHHHHCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHH
HYYNFDEIPFRGQSREGVTISNLRQLFFTPAQIKEENIHKLTLDNAAQHDRQLEEAGGLD
EECCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHCCCCCEEEEECCHHHHHHHHHHHCCCE
LMVLGLGADGHFCGNLPNTTRFHDQTVEVPIHGEMIALIANSEMGGDISAVPNSYVTMGP
EEEEEECCCCCEECCCCCCCEECCCEEEEEECCCEEEEEECCCCCCCEECCCCCEEEECC
RSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASVLKLHPSLVIIADKAAAAELQQ
HHHHHHCCEEEEEECCHHHHHHHHHHCCCCEEEECHHHHHCCCCEEEEECCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]