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The map label for this gene is aglA [H]

Identifier: 238897193

GI number: 238897193

Start: 5191238

End: 5192989

Strand: Reverse

Name: aglA [H]

Synonym: KP1_5463

Alternate gene names: 238897193

Gene position: 5192989-5191238 (Counterclockwise)

Preceding gene: 238897195

Following gene: 238897192

Centisome position: 98.94

GC content: 58.96

Gene sequence:

>1752_bases
ATGAATGGGATCACGAATCGCAACGGCGCGGCATGTTGTCGGACGGGCAAATTTTTATTCTCCAGTCAGGCCGGTAATCA
AGAAAAAGAAGGCCACTCACCCTACGAGTTGTTACATGAGGATTTCCCAATGCTCAGTCAAATACAACGCTTTGGCGGCG
CCATGTTTACCCCGGTTTTGTTGTTTCCTTTTGCCGGGATCGTGGTCGGTATCGCCATCATGCTGCGCAACCCGATGTTC
GTCGGCGAAGCGCTGACCGCACCCGACAGCCTGTTTGCCCAGATCGTTCACATCATTGAGGAGGGCGGCTGGACCGTCTT
TCGTAATATGCCGCTGATTTTCGCCGTCGGTCTGCCGATCGGCCTGGCGAAACAGGCCCAGGGCCGGGCCTGTCTGGCGG
TGCTGGTGAGCTTTCTCACCTGGAACTATTTTATCAACGCCATGGGGATGACCTGGGGCCACTTCTTCGGCGTCGATTTT
TCCGCTGAACCCACGGCCGGCAGCGGCCTGACGATGATTGCCGGGATTAAAACCCTCGACACCAGCATTATCGGCGCCAT
CGTCATCTCCGGTCTGGTGACGGCCCTGCACAATCGCTATTTCGATAAACCCCTGCCGGTATTCCTCGGCATCTTTCAGG
GTTCATCGTTTGTGGTCATTGTCGCCTTCCTCGCGATGATCCCTTGCGCCTGGCTGACCCTGCTCGGCTGGCCAAAGGTC
CAGCTGGGTATTGAATCGCTGCAGGCCTTTCTGCGCTCAGCCGGGGCGCTTGGGGTGTGGGTTTACATCTTCCTTGAGCG
CATCCTGATCCCCACCGGCCTGCACCACTTCGTCTATGGCCCGTTCATCTTTGGCCCTGCGGTGGTGGAGGGCGGACTGC
AGGTCTACTGGGCAGAGCATCTGCAGGCGTTCAGTCAGAGTACGGAACCGCTGAAGACGCTGTTCCCGGAGGGCGGCTTT
GCCCTGCACGGTAACTCGAAAGTGTTTGGGTCGGTGGGGATTGCGCTGGCGCTCTACTTCACCGCCGCGCCGGAAAACCG
CGTCAAGGTCGCCGGACTGCTGATCCCCGCCACCCTGACCGCGATGCTGGTCGGGATCACTGAGCCGCTGGAGTTCACCT
TCCTCTTCATCTCGCCGCTGCTGTTCGCCGTTCATGCGGTGCTGGCGGCGACTATGGCGACGGTGATGTACATCTGCGGG
GTAGTAGGCAACTTCGGCGGCGGCCTGCTCGATCAATTCTTGCCGCAAAACTGGATCCCAATGTTCCATCACCACGCTTC
GATGATGTTCATTCAGATAGGCATCGGCCTCTGTTTCACCGCCCTCTACTTCGTAGTCTTCCGTACCCTGATCCTGCGTC
TGAACCTGAAGACGCCTGGCAGGGAAGAGAGCGAAATCAAGCTCTACAGCAAGGCCGATTACCAGGCGGCACGAGGTAAA
ACCACGGCCGCCGCCGCGCCAGAGACCCGGCTGGGTCAGGCCGCTGGCTTCCTGCAGGCCCTCGGCGGCGCCGACAACAT
TGAAAGCATCAACAACTGCGCCACCCGACTGCGCATCGCGCTGGTCGATATGGCGAAAACGCAAAGTGACGATGTCTTTA
AAGCGCTGGGCGCCCACGGGGTAGTACGCCGCGGCAACGGGATTCAGGTCATCGTCGGCCTGCACGTTCCCCAGGTGCGC
GACCAGCTGGAAAACCTGATGAAAGATTCTCTTTCGACCGAACATACCACCATGACGGAGGCAGTATCATGA

Upstream 100 bases:

>100_bases
ACAATCGATTAAGAAACATTCATTTAGTTAATTTCGATGCCTGACTTATCGATGTCTAACTTTTGTTATCGAAGTAGACA
ACTTTGGCCAAATTAAAACC

Downstream 100 bases:

>100_bases
AAAAATTCTCAGTTGTTATCGCAGGCGGCGGCAGCACCTTCACCCCGGGCATTGTCCTGATGCTGCTGGCAAACCAGGAT
CGTTTTCCGCTGCGGTCGCT

Product: putative alpha-glucoside-specific PTS family enzyme IIBC component

Products: NA

Alternate protein names: Alpha-glucoside permease IIC component; PTS system alpha-glucoside-specific EIIC component; Alpha-glucoside-specific phosphotransferase enzyme IIB component; PTS system alpha-glucoside-specific EIIB component [H]

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MNGITNRNGAACCRTGKFLFSSQAGNQEKEGHSPYELLHEDFPMLSQIQRFGGAMFTPVLLFPFAGIVVGIAIMLRNPMF
VGEALTAPDSLFAQIVHIIEEGGWTVFRNMPLIFAVGLPIGLAKQAQGRACLAVLVSFLTWNYFINAMGMTWGHFFGVDF
SAEPTAGSGLTMIAGIKTLDTSIIGAIVISGLVTALHNRYFDKPLPVFLGIFQGSSFVVIVAFLAMIPCAWLTLLGWPKV
QLGIESLQAFLRSAGALGVWVYIFLERILIPTGLHHFVYGPFIFGPAVVEGGLQVYWAEHLQAFSQSTEPLKTLFPEGGF
ALHGNSKVFGSVGIALALYFTAAPENRVKVAGLLIPATLTAMLVGITEPLEFTFLFISPLLFAVHAVLAATMATVMYICG
VVGNFGGGLLDQFLPQNWIPMFHHHASMMFIQIGIGLCFTALYFVVFRTLILRLNLKTPGREESEIKLYSKADYQAARGK
TTAAAAPETRLGQAAGFLQALGGADNIESINNCATRLRIALVDMAKTQSDDVFKALGAHGVVRRGNGIQVIVGLHVPQVR
DQLENLMKDSLSTEHTTMTEAVS

Sequences:

>Translated_583_residues
MNGITNRNGAACCRTGKFLFSSQAGNQEKEGHSPYELLHEDFPMLSQIQRFGGAMFTPVLLFPFAGIVVGIAIMLRNPMF
VGEALTAPDSLFAQIVHIIEEGGWTVFRNMPLIFAVGLPIGLAKQAQGRACLAVLVSFLTWNYFINAMGMTWGHFFGVDF
SAEPTAGSGLTMIAGIKTLDTSIIGAIVISGLVTALHNRYFDKPLPVFLGIFQGSSFVVIVAFLAMIPCAWLTLLGWPKV
QLGIESLQAFLRSAGALGVWVYIFLERILIPTGLHHFVYGPFIFGPAVVEGGLQVYWAEHLQAFSQSTEPLKTLFPEGGF
ALHGNSKVFGSVGIALALYFTAAPENRVKVAGLLIPATLTAMLVGITEPLEFTFLFISPLLFAVHAVLAATMATVMYICG
VVGNFGGGLLDQFLPQNWIPMFHHHASMMFIQIGIGLCFTALYFVVFRTLILRLNLKTPGREESEIKLYSKADYQAARGK
TTAAAAPETRLGQAAGFLQALGGADNIESINNCATRLRIALVDMAKTQSDDVFKALGAHGVVRRGNGIQVIVGLHVPQVR
DQLENLMKDSLSTEHTTMTEAVS
>Mature_583_residues
MNGITNRNGAACCRTGKFLFSSQAGNQEKEGHSPYELLHEDFPMLSQIQRFGGAMFTPVLLFPFAGIVVGIAIMLRNPMF
VGEALTAPDSLFAQIVHIIEEGGWTVFRNMPLIFAVGLPIGLAKQAQGRACLAVLVSFLTWNYFINAMGMTWGHFFGVDF
SAEPTAGSGLTMIAGIKTLDTSIIGAIVISGLVTALHNRYFDKPLPVFLGIFQGSSFVVIVAFLAMIPCAWLTLLGWPKV
QLGIESLQAFLRSAGALGVWVYIFLERILIPTGLHHFVYGPFIFGPAVVEGGLQVYWAEHLQAFSQSTEPLKTLFPEGGF
ALHGNSKVFGSVGIALALYFTAAPENRVKVAGLLIPATLTAMLVGITEPLEFTFLFISPLLFAVHAVLAATMATVMYICG
VVGNFGGGLLDQFLPQNWIPMFHHHASMMFIQIGIGLCFTALYFVVFRTLILRLNLKTPGREESEIKLYSKADYQAARGK
TTAAAAPETRLGQAAGFLQALGGADNIESINNCATRLRIALVDMAKTQSDDVFKALGAHGVVRRGNGIQVIVGLHVPQVR
DQLENLMKDSLSTEHTTMTEAVS

Specific function: Involved in the transport and simultaneous phosphorylation at O-6 of the glucosyl moiety of sucrose and its five linkage-isomeric alpha-D-glucosyl-D-fructoses. Can also transport maltose, isomaltose and maltitol, phosphorylating at O-6 of their non-reduci

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=534, Percent_Identity=32.2097378277154, Blast_Score=225, Evalue=6e-60,
Organism=Escherichia coli, GI1787343, Length=540, Percent_Identity=30.1851851851852, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1786894, Length=533, Percent_Identity=33.5834896810507, Blast_Score=179, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR010975 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 63112; Mature: 63112

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGITNRNGAACCRTGKFLFSSQAGNQEKEGHSPYELLHEDFPMLSQIQRFGGAMFTPVL
CCCCCCCCCCHHHHCCCHHEECCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCHHHHHHH
LFPFAGIVVGIAIMLRNPMFVGEALTAPDSLFAQIVHIIEEGGWTVFRNMPLIFAVGLPI
HHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHCCCEEEEECCCEEEEECCCC
GLAKQAQGRACLAVLVSFLTWNYFINAMGMTWGHFFGVDFSAEPTAGSGLTMIAGIKTLD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
TSIIGAIVISGLVTALHNRYFDKPLPVFLGIFQGSSFVVIVAFLAMIPCAWLTLLGWPKV
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHH
QLGIESLQAFLRSAGALGVWVYIFLERILIPTGLHHFVYGPFIFGPAVVEGGLQVYWAEH
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
LQAFSQSTEPLKTLFPEGGFALHGNSKVFGSVGIALALYFTAAPENRVKVAGLLIPATLT
HHHHHCCCCHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHH
AMLVGITEPLEFTFLFISPLLFAVHAVLAATMATVMYICGVVGNFGGGLLDQFLPQNWIP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCH
MFHHHASMMFIQIGIGLCFTALYFVVFRTLILRLNLKTPGREESEIKLYSKADYQAARGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEECCCHHHHCCC
TTAAAAPETRLGQAAGFLQALGGADNIESINNCATRLRIALVDMAKTQSDDVFKALGAHG
CCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
VVRRGNGIQVIVGLHVPQVRDQLENLMKDSLSTEHTTMTEAVS
EEECCCCEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHCC
>Mature Secondary Structure
MNGITNRNGAACCRTGKFLFSSQAGNQEKEGHSPYELLHEDFPMLSQIQRFGGAMFTPVL
CCCCCCCCCCHHHHCCCHHEECCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCHHHHHHH
LFPFAGIVVGIAIMLRNPMFVGEALTAPDSLFAQIVHIIEEGGWTVFRNMPLIFAVGLPI
HHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHCCCEEEEECCCEEEEECCCC
GLAKQAQGRACLAVLVSFLTWNYFINAMGMTWGHFFGVDFSAEPTAGSGLTMIAGIKTLD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
TSIIGAIVISGLVTALHNRYFDKPLPVFLGIFQGSSFVVIVAFLAMIPCAWLTLLGWPKV
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHH
QLGIESLQAFLRSAGALGVWVYIFLERILIPTGLHHFVYGPFIFGPAVVEGGLQVYWAEH
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
LQAFSQSTEPLKTLFPEGGFALHGNSKVFGSVGIALALYFTAAPENRVKVAGLLIPATLT
HHHHHCCCCHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHH
AMLVGITEPLEFTFLFISPLLFAVHAVLAATMATVMYICGVVGNFGGGLLDQFLPQNWIP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCH
MFHHHASMMFIQIGIGLCFTALYFVVFRTLILRLNLKTPGREESEIKLYSKADYQAARGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEECCCHHHHCCC
TTAAAAPETRLGQAAGFLQALGGADNIESINNCATRLRIALVDMAKTQSDDVFKALGAHG
CCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
VVRRGNGIQVIVGLHVPQVRDQLENLMKDSLSTEHTTMTEAVS
EEECCCCEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11473129; 11322729 [H]