Click here to switch to the map view.

The map label for this gene is dsdX [H]

Identifier: 238897187

GI number: 238897187

Start: 5185935

End: 5187272

Strand: Direct

Name: dsdX [H]

Synonym: KP1_5457

Alternate gene names: 238897187

Gene position: 5185935-5187272 (Clockwise)

Preceding gene: 238897185

Following gene: 238897188

Centisome position: 98.81

GC content: 58.52

Gene sequence:

>1338_bases
ATGGAATCGCAAATTTGGGTTGTGAGCACATTGCTGATTAGCATCGTGTTAATTGTATTAACCATCGTCAAACTGAAGTT
TCATCCGTTTCTGGCGCTGCTGCTGGCGAGCTTTTTCGTCGGTGCGATGATGGGAATGGGCCCGCTGGAGATGGTCAACG
CCATTGAGAGCGGGATCGGCGGTACGCTGGGCTTCCTGGCGGCGGTGATCGGTCTCGGCACCATTCTCGGCAAGATGATG
GAGGTCTCCGGCGCGGCGGAGCGCATCGGCCTGACGCTCCAGCGCTGCCGCTGGCTGTCGGCGGATGTGATTATGGTGCT
GGTCGGCCTGATCTGCGGCATTACCCTGTTTGTCGAAGTCGGGGTGGTGCTGCTGATCCCGCTGGCATTCTCCATCGCCA
AAAAAACCAATACTTCGCTGCTGAAGCTGGCTATTCCGCTGTGTACCGCGCTGATGGCGGTGCACTGCGTGGTACCGCCG
CATCCGGCCGCGCTGTTCGTGGCGAATAAACTGGGGGCTGATATCGGGACGGTTATCGTCTATGGCCTGCTGGTCGGTCT
GATCGCCTCCCTGGTCGGCGGCCCGCTGTTCCTCAGGCTGCTCGGCAACCGCCTGCCGTTTAAACCAGTGCCAGCCGAGT
TTTCCAACCTCGACGTTCGCGAAGAATCGACGCTGCCGTCGCTCGGCGCTACGCTGTTTACCGTGCTGTTACCGATTGGC
CTGATGCTGGTGAAAACCGTCGCTGAACTGAATATGGCGAAAGGCGGCACGCTGTATACAGTGCTGGAATTTATCGGCAA
CCCCATCACCGCGATGTTTATCGCCGTCTTTGTCGCCTATTACATGCTCGGCATCCGTCGGCAAATGGGGATGGGCGTTC
TGCTGACTCATACCGAAAACGGCTTTGGGTCCATCGCCAACATCCTGCTGATTATCGGCGCCGGCGGCGCATTCAACGCG
ATTTTGAAATCCAGCGGCCTGGCCGATAGCCTCGCGGTGATCCTGTCGAACCTTGATATGCACCCGATTTTGCTGGCCTG
GCTGGTGGCGCTTATCCTGCACGCCGCCGTTGGCTCCGCCACCGTGGCGATGATGGGCGCTACCGCCATCGTTGCCCCGA
TGCTGCCGCTTTATCCCGGCGTAAGCCCGGAGATCATCGCCATTGCCATCGGTTCCGGCGCCATTGGCTGCACGATCGTC
ACCGATTCCCTGTTCTGGCTGGTAAAACAGTACTGCGGCGCCAGCCTCAGTGAAACGTTCAAGTACTACACGACAGCGAC
ATTTATCGCGTCGCTACTTGCACTGGCCGCCACCTTCCTGCTTTCTTTCATCATCTAA

Upstream 100 bases:

>100_bases
TTGATTCAATCTGGCTCATCTGAAAGGTCATTTATATCGTTTGTCAGCCCATGCCGAGTTTCTGTTCAATAACCACACGT
TACTTACGGCGAGGTGGGAT

Downstream 100 bases:

>100_bases
GCGAACGAGACGTAATATGAAAAACGCTGACCTGACCACCTTAACCGCGACCTTCCCGCTTGTGCAGGATCTGATCGCCC
TGAAAGAAACTACCTGGTTT

Product: permease DsdX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MESQIWVVSTLLISIVLIVLTIVKLKFHPFLALLLASFFVGAMMGMGPLEMVNAIESGIGGTLGFLAAVIGLGTILGKMM
EVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPP
HPAALFVANKLGADIGTVIVYGLLVGLIASLVGGPLFLRLLGNRLPFKPVPAEFSNLDVREESTLPSLGATLFTVLLPIG
LMLVKTVAELNMAKGGTLYTVLEFIGNPITAMFIAVFVAYYMLGIRRQMGMGVLLTHTENGFGSIANILLIIGAGGAFNA
ILKSSGLADSLAVILSNLDMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPGVSPEIIAIAIGSGAIGCTIV
TDSLFWLVKQYCGASLSETFKYYTTATFIASLLALAATFLLSFII

Sequences:

>Translated_445_residues
MESQIWVVSTLLISIVLIVLTIVKLKFHPFLALLLASFFVGAMMGMGPLEMVNAIESGIGGTLGFLAAVIGLGTILGKMM
EVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPP
HPAALFVANKLGADIGTVIVYGLLVGLIASLVGGPLFLRLLGNRLPFKPVPAEFSNLDVREESTLPSLGATLFTVLLPIG
LMLVKTVAELNMAKGGTLYTVLEFIGNPITAMFIAVFVAYYMLGIRRQMGMGVLLTHTENGFGSIANILLIIGAGGAFNA
ILKSSGLADSLAVILSNLDMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPGVSPEIIAIAIGSGAIGCTIV
TDSLFWLVKQYCGASLSETFKYYTTATFIASLLALAATFLLSFII
>Mature_445_residues
MESQIWVVSTLLISIVLIVLTIVKLKFHPFLALLLASFFVGAMMGMGPLEMVNAIESGIGGTLGFLAAVIGLGTILGKMM
EVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPP
HPAALFVANKLGADIGTVIVYGLLVGLIASLVGGPLFLRLLGNRLPFKPVPAEFSNLDVREESTLPSLGATLFTVLLPIG
LMLVKTVAELNMAKGGTLYTVLEFIGNPITAMFIAVFVAYYMLGIRRQMGMGVLLTHTENGFGSIANILLIIGAGGAFNA
ILKSSGLADSLAVILSNLDMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPGVSPEIIAIAIGSGAIGCTIV
TDSLFWLVKQYCGASLSETFKYYTTATFIASLLALAATFLLSFII

Specific function: Probable permease for an unknown substrate [H]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI1788707, Length=445, Percent_Identity=89.8876404494382, Blast_Score=795, Evalue=0.0,
Organism=Escherichia coli, GI48994935, Length=439, Percent_Identity=36.2186788154898, Blast_Score=265, Evalue=4e-72,
Organism=Escherichia coli, GI1790716, Length=427, Percent_Identity=33.7236533957845, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1790776, Length=427, Percent_Identity=31.8501170960187, Blast_Score=221, Evalue=8e-59,
Organism=Escherichia coli, GI2367370, Length=427, Percent_Identity=33.9578454332553, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI48994939, Length=415, Percent_Identity=34.9397590361446, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1789097, Length=438, Percent_Identity=30.5936073059361, Blast_Score=169, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 46674; Mature: 46674

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592420; 3275618; 9205837; 9278503; 3029015; 1659648; 12218016 [H]