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The map label for this gene is glxA [H]

Identifier: 238897130

GI number: 238897130

Start: 5129345

End: 5130298

Strand: Reverse

Name: glxA [H]

Synonym: KP1_5389

Alternate gene names: 238897130

Gene position: 5130298-5129345 (Counterclockwise)

Preceding gene: 238897131

Following gene: 238897128

Centisome position: 97.75

GC content: 64.68

Gene sequence:

>954_bases
ATGAAACTCACCGACGTGGCGATTGTCGCTGTAGAGGGCTTTAGCCCGTTTCACTACGCCGTCCCCTGCATGCTGTTTGG
CGATTCGGTTTCGGAAATCAAACGCTTTAATCTGCACATTTGCGCCGAGCGGCCGGGGCTGCTGCGCGCCCGCGATGGTT
TTGCGCTGTACGCCACCGGCGATTTCGCCGCGCTGGAACAGGCGGATATCGTGGTGGTGCCTTACTGGGGCGAGGTCGAT
CGGCGTCCGCCGCAGGCGCTGCTTGATAGCCTGGTGCGGGCCCGGGATAACGGCGCGGAGATTGTCGGCCTGTGTCTCGG
CGCGTTTGTCCTCGGCTACGCCGGGCTGCTGGATGGCAGGCGAGCGGCGACTCACTGGGAGTTCGAGCAGGATTTCCAGC
GCCGGTTTCCGCAGGTGCAGCTGGATATCAACGCCCTGTACGTCGACGACCAGCGGATCATTACTTCGGCGGGCACCGCG
GCGGCGCTGGACTGTTGCCTCTACATCATCCGCCAGCGTTTCGGCAGCCTCGCGGCCAACCAGATCGCCCGGCGGATGAT
TGTTTCGCCGCACCGCGAGGGCGGCCAGGCGCAGTTTATCGCCCAGCCGGTGCCGAAAAACACCCGCGATGCGCGAATCA
ACTGCCTGCTGGATTATCTGCAGCAGCATATTGCCGAGCCGCACAGTCTCGATTCGCTGGCCCGGGTGGTGGCGATGAGC
CGCCGTACCCTGACCCGCCACTTCGCCCGGGCAACCGGGATGAGCATTACCGACTGGCTGACCGCCGAACGTCTGCGCCG
CAGCCAGACTCTGCTTGAGGCGGGCGATCTGCCGGTCGAGCAGGTGGCGGAGGCGGTGGGCTATCTTTCAGCGGTCACCT
GGCGCCAGCAGTTTAAAGCGCGCTTTGGCGTCAGCCCGACGGAATGGCGGCGTACCTTTCGTCGCGGCGCTTAG

Upstream 100 bases:

>100_bases
GATGCGCCAGTATGCGCTGGATAATCAGATTGCCGATGTGGTGAGTATCCCGCAGGATGGGGAAACCGTGGTTTATTAAC
ATGCGCAAGGGGAAAGGACG

Downstream 100 bases:

>100_bases
CCGGCGAGGGTCGCACTGTCGATCACGAAGCGGTATTTCACGTCACCCTTGACCATTCTTTCCCAGGCTTCGTTGATCTC
ATCGCCGCGGATCAGTTCGA

Product: putative helix-turn-helix AraC-type trancriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKLTDVAIVAVEGFSPFHYAVPCMLFGDSVSEIKRFNLHICAERPGLLRARDGFALYATGDFAALEQADIVVVPYWGEVD
RRPPQALLDSLVRARDNGAEIVGLCLGAFVLGYAGLLDGRRAATHWEFEQDFQRRFPQVQLDINALYVDDQRIITSAGTA
AALDCCLYIIRQRFGSLAANQIARRMIVSPHREGGQAQFIAQPVPKNTRDARINCLLDYLQQHIAEPHSLDSLARVVAMS
RRTLTRHFARATGMSITDWLTAERLRRSQTLLEAGDLPVEQVAEAVGYLSAVTWRQQFKARFGVSPTEWRRTFRRGA

Sequences:

>Translated_317_residues
MKLTDVAIVAVEGFSPFHYAVPCMLFGDSVSEIKRFNLHICAERPGLLRARDGFALYATGDFAALEQADIVVVPYWGEVD
RRPPQALLDSLVRARDNGAEIVGLCLGAFVLGYAGLLDGRRAATHWEFEQDFQRRFPQVQLDINALYVDDQRIITSAGTA
AALDCCLYIIRQRFGSLAANQIARRMIVSPHREGGQAQFIAQPVPKNTRDARINCLLDYLQQHIAEPHSLDSLARVVAMS
RRTLTRHFARATGMSITDWLTAERLRRSQTLLEAGDLPVEQVAEAVGYLSAVTWRQQFKARFGVSPTEWRRTFRRGA
>Mature_317_residues
MKLTDVAIVAVEGFSPFHYAVPCMLFGDSVSEIKRFNLHICAERPGLLRARDGFALYATGDFAALEQADIVVVPYWGEVD
RRPPQALLDSLVRARDNGAEIVGLCLGAFVLGYAGLLDGRRAATHWEFEQDFQRRFPQVQLDINALYVDDQRIITSAGTA
AALDCCLYIIRQRFGSLAANQIARRMIVSPHREGGQAQFIAQPVPKNTRDARINCLLDYLQQHIAEPHSLDSLARVVAMS
RRTLTRHFARATGMSITDWLTAERLRRSQTLLEAGDLPVEQVAEAVGYLSAVTWRQQFKARFGVSPTEWRRTFRRGA

Specific function: May Be A Transcriptional Activator Of Genes Involved In The Multiple Antibiotic Resistance (Mar) Phenotype. It Can Also Activate Genes Such As Soda, Zwf And Micf. [C]

COG id: COG4977

COG function: function code K; Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 35533; Mature: 35533

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTDVAIVAVEGFSPFHYAVPCMLFGDSVSEIKRFNLHICAERPGLLRARDGFALYATG
CCCCEEEEEEEECCCCHHHHHHHHHCCCCHHHHHHCCEEEEECCCCCEEECCCEEEEEEC
DFAALEQADIVVVPYWGEVDRRPPQALLDSLVRARDNGAEIVGLCLGAFVLGYAGLLDGR
CHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
RAATHWEFEQDFQRRFPQVQLDINALYVDDQRIITSAGTAAALDCCLYIIRQRFGSLAAN
CHHCCCCHHHHHHHCCCEEEEEEEEEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QIARRMIVSPHREGGQAQFIAQPVPKNTRDARINCLLDYLQQHIAEPHSLDSLARVVAMS
HHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RRTLTRHFARATGMSITDWLTAERLRRSQTLLEAGDLPVEQVAEAVGYLSAVTWRQQFKA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RFGVSPTEWRRTFRRGA
HCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKLTDVAIVAVEGFSPFHYAVPCMLFGDSVSEIKRFNLHICAERPGLLRARDGFALYATG
CCCCEEEEEEEECCCCHHHHHHHHHCCCCHHHHHHCCEEEEECCCCCEEECCCEEEEEEC
DFAALEQADIVVVPYWGEVDRRPPQALLDSLVRARDNGAEIVGLCLGAFVLGYAGLLDGR
CHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
RAATHWEFEQDFQRRFPQVQLDINALYVDDQRIITSAGTAAALDCCLYIIRQRFGSLAAN
CHHCCCCHHHHHHHCCCEEEEEEEEEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QIARRMIVSPHREGGQAQFIAQPVPKNTRDARINCLLDYLQQHIAEPHSLDSLARVVAMS
HHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RRTLTRHFARATGMSITDWLTAERLRRSQTLLEAGDLPVEQVAEAVGYLSAVTWRQQFKA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RFGVSPTEWRRTFRRGA
HCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]