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The map label for this gene is recG [H]

Identifier: 238897102

GI number: 238897102

Start: 5096133

End: 5098214

Strand: Direct

Name: recG [H]

Synonym: KP1_5356

Alternate gene names: 238897102

Gene position: 5096133-5098214 (Clockwise)

Preceding gene: 238897101

Following gene: 238897103

Centisome position: 97.1

GC content: 62.2

Gene sequence:

>2082_bases
ATGTCAGGCCGCCTGTTAGATGCCGTTCCGCTCAGTTCACTCACCGGTGTGGGCGCTGCGCAGAGCAGCAAACTGGCGAA
GATTGGCCTGCATACGGTACAGGATCTGCTGCTGCACCTGCCTTTACGCTACGAAGATCGCACCCATCTTTACCCGATAG
CCGAGCTGCTTCCCGGAGTTTATGCCACCGTGGAAGGTGAAGTGCTCAACAGCAATATCACCTTCGGCGGCCGGCGGATG
ATGACCTGCCAGATCAGCGATGGCACCGGCATCCTCACCATGCGCTTTTTCAACTTCAACGCGGCGATGAAAAACAGCCT
CGCGACCGGTCGTCGGGTGCTGGCCTACGGTGAAGCCAAACGCGGGAAGTACGGCGCCGAGATGATCCACCCGGAATATC
GCGTCCAGGGCGATATGAGCACCCCGGAGCTGCAGGAAACGTTAACCCCAGTCTATCCGACCACCGAAGGCATCAAGCAG
GCGACCCTGCGCAAGCTCACCGATCAGGCGCTTGAGCTCCTGGAAACCTGCGCGATTAGCGAACTCCTCCCGCCGGAGCT
GGCGCAGGGGATGATGAGCCTGCCGGAGGCGCTGCGTACGCTGCACCGCCCGCCTCCCTCCTTGCAACTTAGCGAGCTGG
AAAGCGGCAAGCACCCGGCGCAGCAGCGTCTGATTCTGGAAGAGCTGCTGGCGCATAACCTCAGCATGCTGGCGCTGCGG
GCAGGCGCCCAGCGCTATCACGCCCTGCCGCTCGGCGCCAACGATACCCTGAAAAACCAACTGCTGGCCTCCCTGCCCTT
TAAGCCCACCGGCGCGCAGGCGCGGGTTACCGCCGAGATTGAACACGATATGGCGCTGGACGTGCCGATGATGCGCCTGG
TGCAGGGCGACGTTGGCTCCGGTAAAACGCTGGTCGCTGCCCTGGCCGCCTTGCGCGCTATCGTCCACGGCAAACAGGTG
GCGCTGATGGCGCCCACCGAACTGCTTGCCGAGCAGCATGCCAATAACTTCCGCAACTGGTTCGAACCGCTGGGCATAGA
AGTCGGCTGGCTGGCGGGCAAACAGAAAGGCAAAGCCCGCCAGGCGCAGCAGGAGGCTATCGCCAGCGGCGAAGTGCAGA
TGATTGTCGGCACCCACGCCATCTTCCAGGAGCAGGTGCAGTTTAACGGCCTGGCGCTGGTGATTATTGACGAACAGCAC
CGCTTCGGCGTGCATCAGCGGCTGGCGCTGTGGGAGAAAGGTCAGCAGCAGGGATTCCACCCGCATCAGCTGATCATGAC
CGCCACGCCGATCCCCCGCACCCTGGCGATGACCGCCTACGCCGATCTGGACACCTCGATTATCGACGAGCTGCCGCCAG
GCCGAACTCCGGTGACCACCGTCGCCATCCCCGACACCCGGCGCAGCGATATTATCGACCGCGTGCGCAACGCCTGTACC
CATGAAGGTCGCCAGGCCTATTGGGTCTGTACGCTGATTGAAGAGTCCGATCTGCTGGAAGCCCAGGCGGCGGAAGCCAC
CTGGGAAGAGCTCAAACTGGCGCTGCCGGAGCTCAATATCGGCCTCGTCCACGGGCGGATGAAACCGGCGGAGAAGCAGG
CCGTGATGCAGGCCTTCAAGCAGGGTGAGATGCATCTGCTGGTAGCCACCACGGTGATTGAAGTCGGCGTCGACGTGCCT
AACTCAAGCCTGATGATTATCGAAAACCCGGAACGTCTGGGTCTGGCGCAGCTGCATCAGCTCAGAGGGCGCGTCGGGCG
CGGCGCGGTCGCTTCCCACTGCGTGCTACTCTATAAATCGCCGCTCTCCAAAACGGCGCAGAAACGTCTGCAGGTCCTGC
GCGACAGCAACGATGGTTTCGTCATTGCCCAGAAAGACCTCGAAATTCGCGGTCCCGGCGAGCTGCTCGGCACCCGCCAG
ACCGGCAACGCCGAATTTAAAGTGGCGGACTTACTGCGCGATCAGGCGATGATCCCCGATGTCCAGCGCATTGCTCGCCA
CATTCATGAACGCTATCCGCTGCAGGCCCAGGCGCTTATCGAGCGCTGGATGCCGGAAACCGAACGCTATTCCAACGCGT
AG

Upstream 100 bases:

>100_bases
CCAGACAAAAAGGTCTGCCTTACCCCCACGTTAACGAGCAGGGCGAAGTGGAAGCCGATGCCGCGTGGTGGGCTACCATG
CAGGCTGCGAGGTAAACCCA

Downstream 100 bases:

>100_bases
CGCGCTTTTGCCGCGCTGCGGGCAACTTTTCTACACAACGAGTGGATTATGAAACGAGAACTGGCCATCGAATTTTCGCG
TGTCACCGAAGCCGCCGCGC

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MSGRLLDAVPLSSLTGVGAAQSSKLAKIGLHTVQDLLLHLPLRYEDRTHLYPIAELLPGVYATVEGEVLNSNITFGGRRM
MTCQISDGTGILTMRFFNFNAAMKNSLATGRRVLAYGEAKRGKYGAEMIHPEYRVQGDMSTPELQETLTPVYPTTEGIKQ
ATLRKLTDQALELLETCAISELLPPELAQGMMSLPEALRTLHRPPPSLQLSELESGKHPAQQRLILEELLAHNLSMLALR
AGAQRYHALPLGANDTLKNQLLASLPFKPTGAQARVTAEIEHDMALDVPMMRLVQGDVGSGKTLVAALAALRAIVHGKQV
ALMAPTELLAEQHANNFRNWFEPLGIEVGWLAGKQKGKARQAQQEAIASGEVQMIVGTHAIFQEQVQFNGLALVIIDEQH
RFGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAIPDTRRSDIIDRVRNACT
HEGRQAYWVCTLIEESDLLEAQAAEATWEELKLALPELNIGLVHGRMKPAEKQAVMQAFKQGEMHLLVATTVIEVGVDVP
NSSLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKSPLSKTAQKRLQVLRDSNDGFVIAQKDLEIRGPGELLGTRQ
TGNAEFKVADLLRDQAMIPDVQRIARHIHERYPLQAQALIERWMPETERYSNA

Sequences:

>Translated_693_residues
MSGRLLDAVPLSSLTGVGAAQSSKLAKIGLHTVQDLLLHLPLRYEDRTHLYPIAELLPGVYATVEGEVLNSNITFGGRRM
MTCQISDGTGILTMRFFNFNAAMKNSLATGRRVLAYGEAKRGKYGAEMIHPEYRVQGDMSTPELQETLTPVYPTTEGIKQ
ATLRKLTDQALELLETCAISELLPPELAQGMMSLPEALRTLHRPPPSLQLSELESGKHPAQQRLILEELLAHNLSMLALR
AGAQRYHALPLGANDTLKNQLLASLPFKPTGAQARVTAEIEHDMALDVPMMRLVQGDVGSGKTLVAALAALRAIVHGKQV
ALMAPTELLAEQHANNFRNWFEPLGIEVGWLAGKQKGKARQAQQEAIASGEVQMIVGTHAIFQEQVQFNGLALVIIDEQH
RFGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAIPDTRRSDIIDRVRNACT
HEGRQAYWVCTLIEESDLLEAQAAEATWEELKLALPELNIGLVHGRMKPAEKQAVMQAFKQGEMHLLVATTVIEVGVDVP
NSSLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKSPLSKTAQKRLQVLRDSNDGFVIAQKDLEIRGPGELLGTRQ
TGNAEFKVADLLRDQAMIPDVQRIARHIHERYPLQAQALIERWMPETERYSNA
>Mature_692_residues
SGRLLDAVPLSSLTGVGAAQSSKLAKIGLHTVQDLLLHLPLRYEDRTHLYPIAELLPGVYATVEGEVLNSNITFGGRRMM
TCQISDGTGILTMRFFNFNAAMKNSLATGRRVLAYGEAKRGKYGAEMIHPEYRVQGDMSTPELQETLTPVYPTTEGIKQA
TLRKLTDQALELLETCAISELLPPELAQGMMSLPEALRTLHRPPPSLQLSELESGKHPAQQRLILEELLAHNLSMLALRA
GAQRYHALPLGANDTLKNQLLASLPFKPTGAQARVTAEIEHDMALDVPMMRLVQGDVGSGKTLVAALAALRAIVHGKQVA
LMAPTELLAEQHANNFRNWFEPLGIEVGWLAGKQKGKARQAQQEAIASGEVQMIVGTHAIFQEQVQFNGLALVIIDEQHR
FGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAIPDTRRSDIIDRVRNACTH
EGRQAYWVCTLIEESDLLEAQAAEATWEELKLALPELNIGLVHGRMKPAEKQAVMQAFKQGEMHLLVATTVIEVGVDVPN
SSLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKSPLSKTAQKRLQVLRDSNDGFVIAQKDLEIRGPGELLGTRQT
GNAEFKVADLLRDQAMIPDVQRIARHIHERYPLQAQALIERWMPETERYSNA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=693, Percent_Identity=92.6406926406926, Blast_Score=1304, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=401, Percent_Identity=38.9027431421446, Blast_Score=242, Evalue=6e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76489; Mature: 76358

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRLLDAVPLSSLTGVGAAQSSKLAKIGLHTVQDLLLHLPLRYEDRTHLYPIAELLPGV
CCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHCCCC
YATVEGEVLNSNITFGGRRMMTCQISDGTGILTMRFFNFNAAMKNSLATGRRVLAYGEAK
EEEEECEEEECCCEECCCEEEEEEECCCCCEEEEEEEECCHHHHHHHHCCCEEEEECCCC
RGKYGAEMIHPEYRVQGDMSTPELQETLTPVYPTTEGIKQATLRKLTDQALELLETCAIS
CCCCCHHHCCCCCEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLPPELAQGMMSLPEALRTLHRPPPSLQLSELESGKHPAQQRLILEELLAHNLSMLALR
HCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHH
AGAQRYHALPLGANDTLKNQLLASLPFKPTGAQARVTAEIEHDMALDVPMMRLVQGDVGS
HCCHHHEEECCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCC
GKTLVAALAALRAIVHGKQVALMAPTELLAEQHANNFRNWFEPLGIEVGWLAGKQKGKAR
CHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHH
QAQQEAIASGEVQMIVGTHAIFQEQVQFNGLALVIIDEQHRFGVHQRLALWEKGQQQGFH
HHHHHHHHCCCEEEEECHHHHHHHHHHHCCEEEEEECCCHHCCHHHHHHHHHHHHHCCCC
PHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAIPDTRRSDIIDRVRNACT
CCEEEEECCCCCHHHHHHHHHCCCHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
HEGRQAYWVCTLIEESDLLEAQAAEATWEELKLALPELNIGLVHGRMKPAEKQAVMQAFK
CCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHH
QGEMHLLVATTVIEVGVDVPNSSLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKS
CCCEEEEEEHHHHHHCCCCCCCCEEEEECCHHCCHHHHHHHHHCCCCCHHHHHHHHEECC
PLSKTAQKRLQVLRDSNDGFVIAQKDLEIRGPGELLGTRQTGNAEFKVADLLRDQAMIPD
HHHHHHHHHHHHHHCCCCCEEEEECCCEECCCHHHCCCCCCCCCCCHHHHHHHHHHCCCH
VQRIARHIHERYPLQAQALIERWMPETERYSNA
HHHHHHHHHHHCCCHHHHHHHHHCCCHHHCCCC
>Mature Secondary Structure 
SGRLLDAVPLSSLTGVGAAQSSKLAKIGLHTVQDLLLHLPLRYEDRTHLYPIAELLPGV
CCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHCCCC
YATVEGEVLNSNITFGGRRMMTCQISDGTGILTMRFFNFNAAMKNSLATGRRVLAYGEAK
EEEEECEEEECCCEECCCEEEEEEECCCCCEEEEEEEECCHHHHHHHHCCCEEEEECCCC
RGKYGAEMIHPEYRVQGDMSTPELQETLTPVYPTTEGIKQATLRKLTDQALELLETCAIS
CCCCCHHHCCCCCEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLPPELAQGMMSLPEALRTLHRPPPSLQLSELESGKHPAQQRLILEELLAHNLSMLALR
HCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHH
AGAQRYHALPLGANDTLKNQLLASLPFKPTGAQARVTAEIEHDMALDVPMMRLVQGDVGS
HCCHHHEEECCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCC
GKTLVAALAALRAIVHGKQVALMAPTELLAEQHANNFRNWFEPLGIEVGWLAGKQKGKAR
CHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHH
QAQQEAIASGEVQMIVGTHAIFQEQVQFNGLALVIIDEQHRFGVHQRLALWEKGQQQGFH
HHHHHHHHCCCEEEEECHHHHHHHHHHHCCEEEEEECCCHHCCHHHHHHHHHHHHHCCCC
PHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAIPDTRRSDIIDRVRNACT
CCEEEEECCCCCHHHHHHHHHCCCHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
HEGRQAYWVCTLIEESDLLEAQAAEATWEELKLALPELNIGLVHGRMKPAEKQAVMQAFK
CCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHH
QGEMHLLVATTVIEVGVDVPNSSLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKS
CCCEEEEEEHHHHHHCCCCCCCCEEEEECCHHCCHHHHHHHHHCCCCCHHHHHHHHEECC
PLSKTAQKRLQVLRDSNDGFVIAQKDLEIRGPGELLGTRQTGNAEFKVADLLRDQAMIPD
HHHHHHHHHHHHHHCCCCCEEEEECCCEECCCHHHCCCCCCCCCCCHHHHHHHHHHCCCH
VQRIARHIHERYPLQAQALIERWMPETERYSNA
HHHHHHHHHHHCCCHHHHHHHHHCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]