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The map label for this gene is mtlR [H]

Identifier: 238897044

GI number: 238897044

Start: 5041450

End: 5042049

Strand: Direct

Name: mtlR [H]

Synonym: KP1_5291

Alternate gene names: 238897044

Gene position: 5041450-5042049 (Clockwise)

Preceding gene: 238897043

Following gene: 238897046

Centisome position: 96.05

GC content: 54.67

Gene sequence:

>600_bases
ATGATGCACAACCTGGCGCGGCCGACGTCGCGCCCATTACGACTCCTGTCAGATATGCAGGCAATGATGGAAGAAACACA
AGCATTTGAAAACCGTGTGCTTGAGCGTCTGAATGCTGGCAAAACCGTACGAAGCTTCCTGATCGCCACCGTCGAGCTGT
TAACGGAAGCGGTCAATATTCTGGTGCTTCAGGTGTTCCGTAAAGACGACTACGCGGTGAAATACGCCGTCGAGCCCTTG
CTGGAGGGCAGCGGGCCGCTCGGCGATCTCTCTGTACGCCTGAAGCTGATTTATGGCCTTGGGGTGATAAGTCGTGCCGA
ATATGAAGACGCTGAGCTGCTGATGGCCCTGCGCGAAGAGCTTAACCACGACGGCAATGAGTACAGCTTTACCGACGACG
AAATTATCGGTCCGTTCGGCGAGCTGCACTGCGTCGCCGCCCTGCCGCCAACGCCGCAATTTGATGACAGCGATGCCGAA
CTGCTGGCAATGCAGAAACTGCGTTACCAGCAGATGGTGCGCTCAACGATGGTGCTGTCCCTGACTGAGCTGATTTCACG
AATCAGCTTAAAAAAAGCCTTTCAGAAATCAACGCTCTGA

Upstream 100 bases:

>100_bases
TCGCCGACAAGGGGCCGCAGGCCGCGCTGGCGCAGATTTCCGGCCTGGATGCCGCAAGTGATGTCGTCGCGGAGGCCGTT
AACGACTACAACGCGGAAAA

Downstream 100 bases:

>100_bases
TTCCGGTTCCGTCTGGTCGCAGGTCGGCCGGTAAAGCTGACGATAATATTCCAGACGCTGCAGGAACAACGCTTCCTTAT
CCTGAGGAATGTCTCGCGGT

Product: mannitol repressor protein

Products: NA

Alternate protein names: Mannitol repressor protein [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MMHNLARPTSRPLRLLSDMQAMMEETQAFENRVLERLNAGKTVRSFLIATVELLTEAVNILVLQVFRKDDYAVKYAVEPL
LEGSGPLGDLSVRLKLIYGLGVISRAEYEDAELLMALREELNHDGNEYSFTDDEIIGPFGELHCVAALPPTPQFDDSDAE
LLAMQKLRYQQMVRSTMVLSLTELISRISLKKAFQKSTL

Sequences:

>Translated_199_residues
MMHNLARPTSRPLRLLSDMQAMMEETQAFENRVLERLNAGKTVRSFLIATVELLTEAVNILVLQVFRKDDYAVKYAVEPL
LEGSGPLGDLSVRLKLIYGLGVISRAEYEDAELLMALREELNHDGNEYSFTDDEIIGPFGELHCVAALPPTPQFDDSDAE
LLAMQKLRYQQMVRSTMVLSLTELISRISLKKAFQKSTL
>Mature_199_residues
MMHNLARPTSRPLRLLSDMQAMMEETQAFENRVLERLNAGKTVRSFLIATVELLTEAVNILVLQVFRKDDYAVKYAVEPL
LEGSGPLGDLSVRLKLIYGLGVISRAEYEDAELLMALREELNHDGNEYSFTDDEIIGPFGELHCVAALPPTPQFDDSDAE
LLAMQKLRYQQMVRSTMVLSLTELISRISLKKAFQKSTL

Specific function: Acts as a repressor of the mtlAD operon [H]

COG id: COG3722

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yggD [H]

Homologues:

Organism=Escherichia coli, GI1790029, Length=195, Percent_Identity=84.1025641025641, Blast_Score=332, Evalue=9e-93,
Organism=Escherichia coli, GI1789297, Length=105, Percent_Identity=35.2380952380952, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007761 [H]

Pfam domain/function: PF05068 MtlR [H]

EC number: NA

Molecular weight: Translated: 22464; Mature: 22464

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHNLARPTSRPLRLLSDMQAMMEETQAFENRVLERLNAGKTVRSFLIATVELLTEAVNI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LVLQVFRKDDYAVKYAVEPLLEGSGPLGDLSVRLKLIYGLGVISRAEYEDAELLMALREE
HHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LNHDGNEYSFTDDEIIGPFGELHCVAALPPTPQFDDSDAELLAMQKLRYQQMVRSTMVLS
HCCCCCCCCCCCCHHHCCCHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LTELISRISLKKAFQKSTL
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMHNLARPTSRPLRLLSDMQAMMEETQAFENRVLERLNAGKTVRSFLIATVELLTEAVNI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LVLQVFRKDDYAVKYAVEPLLEGSGPLGDLSVRLKLIYGLGVISRAEYEDAELLMALREE
HHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LNHDGNEYSFTDDEIIGPFGELHCVAALPPTPQFDDSDAELLAMQKLRYQQMVRSTMVLS
HCCCCCCCCCCCCHHHCCCHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LTELISRISLKKAFQKSTL
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]