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The map label for this gene is xylB [H]

Identifier: 238897028

GI number: 238897028

Start: 5019438

End: 5020892

Strand: Reverse

Name: xylB [H]

Synonym: KP1_5275

Alternate gene names: 238897028

Gene position: 5020892-5019438 (Counterclockwise)

Preceding gene: 238897029

Following gene: 238897027

Centisome position: 95.66

GC content: 65.5

Gene sequence:

>1455_bases
ATGTATATCGGCATCGATCTGGGGACGTCGGGCGTCAAAGCCATCCTGCTCAATGAGCAGGGTGAGGTAGTGGCATCGCA
TACCGAAAAACTCACCGTCTCGCGTCCGCATCCGCTGTGGTCGGAGCAAGATCCCGAACAGTGGTGGCTGGCGACGGACA
CGGCGATGAAAGCCCTGGGCGCGCAGCATAGCCTGCGCGACGTGAAGGCGCTGGGCATTGCCGGGCAGATGCACGGCGCC
ACCCTACTGGATAAATCGTTACAGGTGCTGCGTCCGGCCATTTTATGGAATGACGGCCGCTGCGCCGAAGAGTGCCAGCT
GCTGGAAGACAAAGTCAGCGCTTCCCGGCAGATCACCGGCAACCTGATGATGCCGGGCTTTACGGCGCCGAAGCTCTTAT
GGGTACAGCGCCACGAGGCGGCAGTGTTCAGCCAGGTCGATAAAGTGCTGCTGCCCAAGGATTATCTGCGCCTGCGCATG
ACCGGCGAGCTCGCCAGCGATATGTCTGACGCCGCCGGCACGATGTGGCTGGACGTCGCCCGGCGCGACTGGAGCGACGA
GATGCTCGCCGCCTGCGATCTCAGTCGGGATGCGATGCCGGCGCTGTTCGAAGGCAGCGACGTCACCGGGCAACTGCGAC
CTGAGGTGGCGCAGGCGTGGAATATGCCGCCGGCGCTGGTGGTGGGCGGCGGGGGCGACAACGCCGCGGGCGCGGTCGGG
GTCGGCATGGCCGATGCCGGTCAGGCGATGCTGTCGCTGGGTACGTCTGGCGTCTACTTCGCCGTCAGTGAAGGGTTCCT
TAGCAAACCCGAAAGCGCGGTGCACAGCTTCTGCCATGCCCTGCCGGGCCGCTGGCATTTGATGTCGGTGATGCTCAGCG
CGGCCTCCTGTCTGGACTGGGCGGCAAAATTAACCGGTCTCGCCAGCGTGCCGGCGCTGATCGCGGCGGCGCAGACGGCG
GATGAAAGCGCCGGTCCGGTGTGGTTCCTGCCCTATCTGTCTGGCGAACGCACGCCGCACAACAACCCGCAGGCTAAGGG
CGTCTTTTTTGGCCTGACGCATCAGCATGGGCCGGCAGAGCTGGCGCGGGCGGTGCTGGAGGGGGTGGGCTATGCGCTGG
CGGATGGTATGGACGTGGTGCACGCCTGCGGCATCAAGCCGCAGAGCATCACGCTTATCGGCGGCGGGGCGCGCAGCGCT
TACTGGCGGCAAATGCTGGCGGATATCAGCGGCCTGCAGCTCGATTACCGTACCGGGGGCGATGTCGGCCCGGCGCTGGG
GGCGGCCAGGCTGGCGCAGCTGGCGGTTCACGACGAGGCAGACCGCCCCGGGCTGCTGAAGCCGCTGCCGCTTGAACAAG
CCCATCGCCCAGACGATCGCCGTGTGGCCCACTATGCGCCGCAGCGGGAAACCTTCCGCCAGATTTATCAGCAACTGAAA
CCGCTGATGTCTTAG

Upstream 100 bases:

>100_bases
ACAAGTAATCATACGGCGGTGCCCGGGGTGACCGGCGCCGCAACCAGGATGCTCTGTTCGCGCCACGCTCAGCCGTGGCG
CGCGTTTAAGGAGAGGGAGT

Downstream 100 bases:

>100_bases
CCTCAGTCCGTCCGGCAGCGCCGGGCGGATTCCCTTCCTGAATGTCCCGGCTACATCCATCCATAAATGCGTATTTATTT
ATTCCGAAATCTCCGCTTTG

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MYIGIDLGTSGVKAILLNEQGEVVASHTEKLTVSRPHPLWSEQDPEQWWLATDTAMKALGAQHSLRDVKALGIAGQMHGA
TLLDKSLQVLRPAILWNDGRCAEECQLLEDKVSASRQITGNLMMPGFTAPKLLWVQRHEAAVFSQVDKVLLPKDYLRLRM
TGELASDMSDAAGTMWLDVARRDWSDEMLAACDLSRDAMPALFEGSDVTGQLRPEVAQAWNMPPALVVGGGGDNAAGAVG
VGMADAGQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPGRWHLMSVMLSAASCLDWAAKLTGLASVPALIAAAQTA
DESAGPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPAELARAVLEGVGYALADGMDVVHACGIKPQSITLIGGGARSA
YWRQMLADISGLQLDYRTGGDVGPALGAARLAQLAVHDEADRPGLLKPLPLEQAHRPDDRRVAHYAPQRETFRQIYQQLK
PLMS

Sequences:

>Translated_484_residues
MYIGIDLGTSGVKAILLNEQGEVVASHTEKLTVSRPHPLWSEQDPEQWWLATDTAMKALGAQHSLRDVKALGIAGQMHGA
TLLDKSLQVLRPAILWNDGRCAEECQLLEDKVSASRQITGNLMMPGFTAPKLLWVQRHEAAVFSQVDKVLLPKDYLRLRM
TGELASDMSDAAGTMWLDVARRDWSDEMLAACDLSRDAMPALFEGSDVTGQLRPEVAQAWNMPPALVVGGGGDNAAGAVG
VGMADAGQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPGRWHLMSVMLSAASCLDWAAKLTGLASVPALIAAAQTA
DESAGPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPAELARAVLEGVGYALADGMDVVHACGIKPQSITLIGGGARSA
YWRQMLADISGLQLDYRTGGDVGPALGAARLAQLAVHDEADRPGLLKPLPLEQAHRPDDRRVAHYAPQRETFRQIYQQLK
PLMS
>Mature_484_residues
MYIGIDLGTSGVKAILLNEQGEVVASHTEKLTVSRPHPLWSEQDPEQWWLATDTAMKALGAQHSLRDVKALGIAGQMHGA
TLLDKSLQVLRPAILWNDGRCAEECQLLEDKVSASRQITGNLMMPGFTAPKLLWVQRHEAAVFSQVDKVLLPKDYLRLRM
TGELASDMSDAAGTMWLDVARRDWSDEMLAACDLSRDAMPALFEGSDVTGQLRPEVAQAWNMPPALVVGGGGDNAAGAVG
VGMADAGQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPGRWHLMSVMLSAASCLDWAAKLTGLASVPALIAAAQTA
DESAGPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPAELARAVLEGVGYALADGMDVVHACGIKPQSITLIGGGARSA
YWRQMLADISGLQLDYRTGGDVGPALGAARLAQLAVHDEADRPGLLKPLPLEQAHRPDDRRVAHYAPQRETFRQIYQQLK
PLMS

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393575, Length=437, Percent_Identity=23.3409610983982, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI42794763, Length=439, Percent_Identity=22.0956719817768, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI4504007, Length=438, Percent_Identity=22.6027397260274, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI189409120, Length=438, Percent_Identity=22.6027397260274, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI88196792, Length=502, Percent_Identity=23.5059760956175, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI164663828, Length=466, Percent_Identity=24.2489270386266, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI164663830, Length=489, Percent_Identity=22.9038854805726, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1789987, Length=484, Percent_Identity=84.7107438016529, Blast_Score=807, Evalue=0.0,
Organism=Escherichia coli, GI1790361, Length=480, Percent_Identity=26.25, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1790005, Length=481, Percent_Identity=24.5322245322245, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787789, Length=512, Percent_Identity=23.828125, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1789168, Length=422, Percent_Identity=25.8293838862559, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17535599, Length=453, Percent_Identity=24.0618101545254, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI17864214, Length=475, Percent_Identity=24.6315789473684, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24654573, Length=418, Percent_Identity=24.8803827751196, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21356607, Length=320, Percent_Identity=24.375, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24657106, Length=252, Percent_Identity=24.6031746031746, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24657102, Length=252, Percent_Identity=24.6031746031746, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 51960; Mature: 51960

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIGIDLGTSGVKAILLNEQGEVVASHTEKLTVSRPHPLWSEQDPEQWWLATDTAMKALG
CEEEEEECCCCEEEEEECCCCCEEECCCCEEEECCCCCCCCCCCCHHEEEEHHHHHHHHC
AQHSLRDVKALGIAGQMHGATLLDKSLQVLRPAILWNDGRCAEECQLLEDKVSASRQITG
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHCCEECC
NLMMPGFTAPKLLWVQRHEAAVFSQVDKVLLPKDYLRLRMTGELASDMSDAAGTMWLDVA
CEECCCCCCCCEEEEHHHHHHHHHHHHHHHCCHHHHEEEECHHHHHHHHHHCCHHHHHHH
RRDWSDEMLAACDLSRDAMPALFEGSDVTGQLRPEVAQAWNMPPALVVGGGGDNAAGAVG
HCCCCHHHHHHHCCCCCCCCCEECCCCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCEEE
VGMADAGQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPGRWHLMSVMLSAASCLDW
CCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AAKLTGLASVPALIAAAQTADESAGPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPAE
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCHHH
LARAVLEGVGYALADGMDVVHACGIKPQSITLIGGGARSAYWRQMLADISGLQLDYRTGG
HHHHHHHHCCHHHHCCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEECCCC
DVGPALGAARLAQLAVHDEADRPGLLKPLPLEQAHRPDDRRVAHYAPQRETFRQIYQQLK
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCHHHCCCCHHHHHHHHHHHH
PLMS
HHCC
>Mature Secondary Structure
MYIGIDLGTSGVKAILLNEQGEVVASHTEKLTVSRPHPLWSEQDPEQWWLATDTAMKALG
CEEEEEECCCCEEEEEECCCCCEEECCCCEEEECCCCCCCCCCCCHHEEEEHHHHHHHHC
AQHSLRDVKALGIAGQMHGATLLDKSLQVLRPAILWNDGRCAEECQLLEDKVSASRQITG
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHCCEECC
NLMMPGFTAPKLLWVQRHEAAVFSQVDKVLLPKDYLRLRMTGELASDMSDAAGTMWLDVA
CEECCCCCCCCEEEEHHHHHHHHHHHHHHHCCHHHHEEEECHHHHHHHHHHCCHHHHHHH
RRDWSDEMLAACDLSRDAMPALFEGSDVTGQLRPEVAQAWNMPPALVVGGGGDNAAGAVG
HCCCCHHHHHHHCCCCCCCCCEECCCCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCEEE
VGMADAGQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPGRWHLMSVMLSAASCLDW
CCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AAKLTGLASVPALIAAAQTADESAGPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPAE
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCHHH
LARAVLEGVGYALADGMDVVHACGIKPQSITLIGGGARSAYWRQMLADISGLQLDYRTGG
HHHHHHHHCCHHHHCCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEECCCC
DVGPALGAARLAQLAVHDEADRPGLLKPLPLEQAHRPDDRRVAHYAPQRETFRQIYQQLK
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCHHHCCCCHHHHHHHHHHHH
PLMS
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1324398 [H]