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The map label for this gene is kdgR [H]

Identifier: 238897011

GI number: 238897011

Start: 5002491

End: 5003507

Strand: Direct

Name: kdgR [H]

Synonym: KP1_5257

Alternate gene names: 238897011

Gene position: 5002491-5003507 (Clockwise)

Preceding gene: 238897010

Following gene: 238897012

Centisome position: 95.31

GC content: 61.55

Gene sequence:

>1017_bases
ATGGCGAAAGCGGCGCGTGCAACTATCAGCGATGTGGCGAAAGCCGCAAAGACCGGCAAAACCAGCATTTCACGTTATCT
TAACGGCGAGAAGCATCTGCTTTCCGACGACTTGTTATCACGTATTGAAAAAGCCATTGCCGAACTCGACTACCGCCCCA
GCCTGATGGCCCGCGGCCTCAAGCACGGCCGAACCCGCCTCATCGGCCTGATCATCGCCGATATCACCAATCCCTACTCG
GTCAACGTCATGAGCGGCATTGAAGCAGCCTGCCGGGAAAAGGGCTTCACCCTGCTGGTGTGTAATACCAATAACGAGCT
CGATCAGGAGCTGCACTACCTGGACCTGCTGCGCAGCTACCAGGTGGAAGGCATCGTGGTCAACGCAGTCGGTATGCGGG
AGGATGGCCTGAACCGCCTGCAGCAGTCGGCCCTGCCGATGGTGCTGATTGACCGTAAAATCCCCGACTTCGCCTGCGAT
GTGGTCGGGCTTGATAACGCCCAGGCCGCCACCACCGCCACCGAACATCTGGTGGAAAAAGGATTCGAGGCCATCCTGTT
TCTCAGCGAACCGCTGGGCTCGGTGAATACCCGTCGCGAGCGCCTGAGCGCCTTTCGCGCCACGCTTGCCCGCCACCACG
GCGTGGTGGCCGAAAACGCCGAGGTGCAGCTTAACGACGGCGCGATGCTGGACAACGTCCTGCGTCAGTTCCATGCCCGC
CACCGCGGGATGCGCAAAGCGGTCATCTCCGCCAACGGCGCGCTGACGCTGCAGGTAGCCCGCGCCCTGAAGCGCGTCGG
CCTGATCTGGGGGAGCGATATCGGCCTGCTGGGCTTCGACGAACTGGAGTGGGCGGAGCTGGCCGGCGTCGGTATTACCA
CCCTCAAACAGCCGACGTGGCAGATCGGCTACGCGGCGGTCGAACAGGTTATTCGGCGCATTGCCGGCACTAACGACCCC
ATCCGCGAACGGGTATTTTCCGGCGAGCTTATCGTCCGCGGATCAACCTCCCGTTAA

Upstream 100 bases:

>100_bases
CATCTTCATATCGCCCGGCAGCCGTTCTGCCGGGCAAAATGCTTGATATCGCTATTTTTCGCGCTAAGGTGTTGGCAGAT
TTTCAGCAAAGGAAGCCACC

Downstream 100 bases:

>100_bases
CGATCCTTCGTGATGCCGATCATAAATTAAACATCTCGCCCTTTCTTATGGAACCGATACCATCTAGCGTATTAAGGAGA
TTAAGCAACAAACGCCGGGA

Product: putative transcriptional regulator

Products: NA

Alternate protein names: Kdg operon repressor [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MAKAARATISDVAKAAKTGKTSISRYLNGEKHLLSDDLLSRIEKAIAELDYRPSLMARGLKHGRTRLIGLIIADITNPYS
VNVMSGIEAACREKGFTLLVCNTNNELDQELHYLDLLRSYQVEGIVVNAVGMREDGLNRLQQSALPMVLIDRKIPDFACD
VVGLDNAQAATTATEHLVEKGFEAILFLSEPLGSVNTRRERLSAFRATLARHHGVVAENAEVQLNDGAMLDNVLRQFHAR
HRGMRKAVISANGALTLQVARALKRVGLIWGSDIGLLGFDELEWAELAGVGITTLKQPTWQIGYAAVEQVIRRIAGTNDP
IRERVFSGELIVRGSTSR

Sequences:

>Translated_338_residues
MAKAARATISDVAKAAKTGKTSISRYLNGEKHLLSDDLLSRIEKAIAELDYRPSLMARGLKHGRTRLIGLIIADITNPYS
VNVMSGIEAACREKGFTLLVCNTNNELDQELHYLDLLRSYQVEGIVVNAVGMREDGLNRLQQSALPMVLIDRKIPDFACD
VVGLDNAQAATTATEHLVEKGFEAILFLSEPLGSVNTRRERLSAFRATLARHHGVVAENAEVQLNDGAMLDNVLRQFHAR
HRGMRKAVISANGALTLQVARALKRVGLIWGSDIGLLGFDELEWAELAGVGITTLKQPTWQIGYAAVEQVIRRIAGTNDP
IRERVFSGELIVRGSTSR
>Mature_337_residues
AKAARATISDVAKAAKTGKTSISRYLNGEKHLLSDDLLSRIEKAIAELDYRPSLMARGLKHGRTRLIGLIIADITNPYSV
NVMSGIEAACREKGFTLLVCNTNNELDQELHYLDLLRSYQVEGIVVNAVGMREDGLNRLQQSALPMVLIDRKIPDFACDV
VGLDNAQAATTATEHLVEKGFEAILFLSEPLGSVNTRRERLSAFRATLARHHGVVAENAEVQLNDGAMLDNVLRQFHARH
RGMRKAVISANGALTLQVARALKRVGLIWGSDIGLLGFDELEWAELAGVGITTLKQPTWQIGYAAVEQVIRRIAGTNDPI
RERVFSGELIVRGSTSR

Specific function: Transcriptional repressor of the kdg operon for pectin utilization [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=313, Percent_Identity=29.073482428115, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1790369, Length=340, Percent_Identity=27.3529411764706, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1788474, Length=336, Percent_Identity=25.297619047619, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1787948, Length=317, Percent_Identity=29.6529968454259, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789202, Length=335, Percent_Identity=25.9701492537313, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787906, Length=346, Percent_Identity=25.7225433526012, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789068, Length=336, Percent_Identity=24.1071428571429, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786268, Length=198, Percent_Identity=29.2929292929293, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787580, Length=322, Percent_Identity=23.2919254658385, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI48994940, Length=321, Percent_Identity=23.0529595015576, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790715, Length=342, Percent_Identity=23.6842105263158, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786540, Length=309, Percent_Identity=23.6245954692557, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37088; Mature: 36957

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAARATISDVAKAAKTGKTSISRYLNGEKHLLSDDLLSRIEKAIAELDYRPSLMARGL
CCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KHGRTRLIGLIIADITNPYSVNVMSGIEAACREKGFTLLVCNTNNELDQELHYLDLLRSY
HHHHHHHHHHHEEECCCCEEEEHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHC
QVEGIVVNAVGMREDGLNRLQQSALPMVLIDRKIPDFACDVVGLDNAQAATTATEHLVEK
CCCEEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCHHHHEEECCCCHHHHHHHHHHHHC
GFEAILFLSEPLGSVNTRRERLSAFRATLARHHGVVAENAEVQLNDGAMLDNVLRQFHAR
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEECCCEEEECCCHHHHHHHHHHHHH
HRGMRKAVISANGALTLQVARALKRVGLIWGSDIGLLGFDELEWAELAGVGITTLKQPTW
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCHHHCCCCCH
QIGYAAVEQVIRRIAGTNDPIRERVFSGELIVRGSTSR
HHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEECCCCC
>Mature Secondary Structure 
AKAARATISDVAKAAKTGKTSISRYLNGEKHLLSDDLLSRIEKAIAELDYRPSLMARGL
CCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KHGRTRLIGLIIADITNPYSVNVMSGIEAACREKGFTLLVCNTNNELDQELHYLDLLRSY
HHHHHHHHHHHEEECCCCEEEEHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHC
QVEGIVVNAVGMREDGLNRLQQSALPMVLIDRKIPDFACDVVGLDNAQAATTATEHLVEK
CCCEEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCHHHHEEECCCCHHHHHHHHHHHHC
GFEAILFLSEPLGSVNTRRERLSAFRATLARHHGVVAENAEVQLNDGAMLDNVLRQFHAR
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEECCCEEEECCCHHHHHHHHHHHHH
HRGMRKAVISANGALTLQVARALKRVGLIWGSDIGLLGFDELEWAELAGVGITTLKQPTW
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCHHHCCCCCH
QIGYAAVEQVIRRIAGTNDPIRERVFSGELIVRGSTSR
HHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]