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The map label for this gene is dppB [H]

Identifier: 238896999

GI number: 238896999

Start: 4987401

End: 4988420

Strand: Reverse

Name: dppB [H]

Synonym: KP1_5244

Alternate gene names: 238896999

Gene position: 4988420-4987401 (Counterclockwise)

Preceding gene: 238897000

Following gene: 238896998

Centisome position: 95.04

GC content: 59.51

Gene sequence:

>1020_bases
ATGTTGCAGTTTATTCTCCGACGTCTGGGACTAGTCATCCCGACATTTATCGGTATCACCCTTCTCACCTTTGCCTTCGT
CCATATGATCCCCGGCGATCCGGTGATGATTATGGCGGGCGAACGTGGTATTTCCCCCGAACGTCACGCGCAGCTGCTGG
CCGAAATGGGCCTTGATAAGCCGCTGTGGCAGCAATATGCCCACTATATCTGGGGCGTGCTGCACGGCGATTTAGGCATC
TCGCTGAAAAGCCGCATTCCCGTGTGGCAGGAGTTTGTCCCACGCTTTAAAGCCACCCTTGAGCTGGGCGTCTGCGCGAT
GATCTTCGCCGTCGCCGTCGGCATTCCGGTGGGCGTGCTGGCTGCGGTAAAACGCGGCTCCATCTTTGACCACACCGCGG
TGGGCCTGGCGCTGACCGGCTACTCAATGCCTATCTTCTGGTGGGGCATGATGCTGATTATGCTGGTTTCGGTGCAGCTA
AACCTGACGCCGGTCTCCGGGCGCATCAGCGATACGGTGTTCCTTGACGATACCCTGCCGCTGACCGGCTTTATGCTGAT
CGACACCGCCATCTGGGGCGAGCAGGGCGACTTTATTGACGCCTTAATGCATATGATCCTGCCCGCTATCGTGCTGGGCA
CCATCCCGCTGGCGGTGATCGTGCGTATGACCCGTTCGTCGATGCTGGAAGTGCTTGGCGAAGACTATATCCGTACCGCG
CGCGCCAAAGGCCTGACCCGGATGCGGGTGATCGTGATCCACGCGCTGCGTAACGCGATGCTGCCGGTGGTCACGGTGAT
TGGTCTGCAGGTGGGCACCCTGCTGGCGGGCGCCATCCTGACGGAAACCATTTTCTCATGGCCTGGTTTAGGTCGCTGGC
TGATCGACGCGCTGCAGCGTCGCGATTATCCGGTGGTGCAGGGCGGGGTGCTGCTGGTGGCGACGATGATTATCCTCGTT
AACCTGCTGGTCGACCTGCTGTACGGCGTGGTGAACCCGCGTATCCGGCATAAGAAGTAA

Upstream 100 bases:

>100_bases
GAGAGGCGGGGGGCGTATTCCCGCTATTCCGGGGAATGCTTTTGTGAGCAATACAGACGCCCTGTCGCCAGGCGGGGCGT
CACTAGAGAGAATCCGGGTT

Downstream 100 bases:

>100_bases
GGGGCCATCATGTCACAAGTTACTGAAAATAAAGTTATCGCTGCGCCGGTACCCATGACTCCGCTGCAGGAGTTCTGGCA
CTATTTCAAACGCAACAAAG

Product: dipeptide transporter permease DppB

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGISPERHAQLLAEMGLDKPLWQQYAHYIWGVLHGDLGI
SLKSRIPVWQEFVPRFKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVQL
NLTPVSGRISDTVFLDDTLPLTGFMLIDTAIWGEQGDFIDALMHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTA
RAKGLTRMRVIVIHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILV
NLLVDLLYGVVNPRIRHKK

Sequences:

>Translated_339_residues
MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGISPERHAQLLAEMGLDKPLWQQYAHYIWGVLHGDLGI
SLKSRIPVWQEFVPRFKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVQL
NLTPVSGRISDTVFLDDTLPLTGFMLIDTAIWGEQGDFIDALMHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTA
RAKGLTRMRVIVIHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILV
NLLVDLLYGVVNPRIRHKK
>Mature_339_residues
MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGISPERHAQLLAEMGLDKPLWQQYAHYIWGVLHGDLGI
SLKSRIPVWQEFVPRFKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVQL
NLTPVSGRISDTVFLDDTLPLTGFMLIDTAIWGEQGDFIDALMHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTA
RAKGLTRMRVIVIHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILV
NLLVDLLYGVVNPRIRHKK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=94.1002949852507, Blast_Score=640, Evalue=0.0,
Organism=Escherichia coli, GI1787053, Length=342, Percent_Identity=42.3976608187134, Blast_Score=269, Evalue=2e-73,
Organism=Escherichia coli, GI1787761, Length=329, Percent_Identity=43.7689969604863, Blast_Score=234, Evalue=9e-63,
Organism=Escherichia coli, GI1787550, Length=283, Percent_Identity=38.1625441696113, Blast_Score=208, Evalue=4e-55,
Organism=Escherichia coli, GI1789888, Length=341, Percent_Identity=33.4310850439883, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1787497, Length=338, Percent_Identity=35.5029585798817, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1788504, Length=378, Percent_Identity=28.3068783068783, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37420; Mature: 37420

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGISPERHAQLLAEMGLDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCC
PLWQQYAHYIWGVLHGDLGISLKSRIPVWQEFVPRFKATLELGVCAMIFAVAVGIPVGVL
HHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVQLNLTPVSGRISDTVFLDDTLP
HHHHCCCCCHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCCC
LTGFMLIDTAIWGEQGDFIDALMHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAKGLTRMRVIVIHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQR
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPRIRHKK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGISPERHAQLLAEMGLDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCC
PLWQQYAHYIWGVLHGDLGISLKSRIPVWQEFVPRFKATLELGVCAMIFAVAVGIPVGVL
HHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVQLNLTPVSGRISDTVFLDDTLP
HHHHCCCCCHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCCC
LTGFMLIDTAIWGEQGDFIDALMHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAKGLTRMRVIVIHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQR
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPRIRHKK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]