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The map label for this gene is dppC [H]

Identifier: 238896998

GI number: 238896998

Start: 4986489

End: 4987391

Strand: Reverse

Name: dppC [H]

Synonym: KP1_5243

Alternate gene names: 238896998

Gene position: 4987391-4986489 (Counterclockwise)

Preceding gene: 238896999

Following gene: 238896997

Centisome position: 95.02

GC content: 63.01

Gene sequence:

>903_bases
ATGTCACAAGTTACTGAAAATAAAGTTATCGCTGCGCCGGTACCCATGACTCCGCTGCAGGAGTTCTGGCACTATTTCAA
ACGCAACAAAGGGGCGGTCGTCGGGCTGGTATACGTGGTGGTGATGATCGTCATCGCGGTATTCGCCAACTTCCTCGCCC
CCTATAACCCGGCGGATCAGTTCCGTGATTCGCTGCTGGCGCCGCCGTTCTGGCAGGACGGCGGCAGCATGGCGCATCTG
CTCGGCACCGACGACGTGGGCCGCGATATTCTGTCGCGCCTGATGTACGGCGCCCGCCTGTCGCTGCTGGTGGGCTGCCT
GGTGGTGGTCCTGTCGCTGATCCTCGGCGTGGTGCTCGGCCTGGTGGCGGGCTATTTCGGCGGAGTGGTGGACTCAATCA
TCATGCGCGTCGTCGATATTATGCTGGCGCTGCCGAGTCTGCTGCTGGCGCTGGTGCTGGTGGCAATCTTCGGGCCCTCC
ATCGTCAACGCCTCGCTGGCGCTAACCTTCGTGGCGCTCCCGCACTATGTGCGTCTCACGCGCGCCGCGGTGCTGGTGGA
GGTCAACCGTGACTACGTGACCGCCTCCCGCGTAGCGGGCGCCGGCGCGATGCGCCAGATGTTCGTTAATATTCTGCCTA
ACTGTCTCGCGCCGCTGATCGTTCAGGCGTCGCTGGGCTTTTCCAACGCCATTCTCGACATGGCAGCGCTGGGGTTCCTC
GGCATGGGCGCGCAGCCGCCGACGCCGGAGTGGGGCACCATGCTTTCCGACGTGTTGCAGTTCGCGCAGAGCGCCTGGTG
GGTAGTCACCTTCCCGGGCGTGGCGATCCTGCTGACGGTGCTGGCATTTAACCTGATGGGTGACGGTCTGCGTGACGCGC
TCGATCCCAAACTGAAGCAGTAA

Upstream 100 bases:

>100_bases
GCTGCTGGTGGCGACGATGATTATCCTCGTTAACCTGCTGGTCGACCTGCTGTACGGCGTGGTGAACCCGCGTATCCGGC
ATAAGAAGTAAGGGGCCATC

Downstream 100 bases:

>100_bases
GAGGTTCGAGATGGCGTTATTGAATGTAGATAAATTATCGGTGCATTTCGGCGATGAAAACGCGCCGTTCCGCGCCGTAG
ACCGCATCAGCTATAGCGTG

Product: dipeptide transporter

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSQVTENKVIAAPVPMTPLQEFWHYFKRNKGAVVGLVYVVVMIVIAVFANFLAPYNPADQFRDSLLAPPFWQDGGSMAHL
LGTDDVGRDILSRLMYGARLSLLVGCLVVVLSLILGVVLGLVAGYFGGVVDSIIMRVVDIMLALPSLLLALVLVAIFGPS
IVNASLALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFVNILPNCLAPLIVQASLGFSNAILDMAALGFL
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGVAILLTVLAFNLMGDGLRDALDPKLKQ

Sequences:

>Translated_300_residues
MSQVTENKVIAAPVPMTPLQEFWHYFKRNKGAVVGLVYVVVMIVIAVFANFLAPYNPADQFRDSLLAPPFWQDGGSMAHL
LGTDDVGRDILSRLMYGARLSLLVGCLVVVLSLILGVVLGLVAGYFGGVVDSIIMRVVDIMLALPSLLLALVLVAIFGPS
IVNASLALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFVNILPNCLAPLIVQASLGFSNAILDMAALGFL
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGVAILLTVLAFNLMGDGLRDALDPKLKQ
>Mature_299_residues
SQVTENKVIAAPVPMTPLQEFWHYFKRNKGAVVGLVYVVVMIVIAVFANFLAPYNPADQFRDSLLAPPFWQDGGSMAHLL
GTDDVGRDILSRLMYGARLSLLVGCLVVVLSLILGVVLGLVAGYFGGVVDSIIMRVVDIMLALPSLLLALVLVAIFGPSI
VNASLALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFVNILPNCLAPLIVQASLGFSNAILDMAALGFLG
MGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGVAILLTVLAFNLMGDGLRDALDPKLKQ

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=300, Percent_Identity=92.3333333333333, Blast_Score=490, Evalue=1e-140,
Organism=Escherichia coli, GI1787054, Length=284, Percent_Identity=41.9014084507042, Blast_Score=233, Evalue=9e-63,
Organism=Escherichia coli, GI1787760, Length=265, Percent_Identity=45.6603773584906, Blast_Score=225, Evalue=2e-60,
Organism=Escherichia coli, GI1787549, Length=288, Percent_Identity=39.9305555555556, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1789889, Length=252, Percent_Identity=38.4920634920635, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1787498, Length=297, Percent_Identity=32.6599326599327, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1788505, Length=223, Percent_Identity=30.9417040358744, Blast_Score=105, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32197; Mature: 32066

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVTENKVIAAPVPMTPLQEFWHYFKRNKGAVVGLVYVVVMIVIAVFANFLAPYNPADQ
CCCCCCCCEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
FRDSLLAPPFWQDGGSMAHLLGTDDVGRDILSRLMYGARLSLLVGCLVVVLSLILGVVLG
HHHHHCCCCCCCCCCCEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVAGYFGGVVDSIIMRVVDIMLALPSLLLALVLVAIFGPSIVNASLALTFVALPHYVRLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
RAAVLVEVNRDYVTASRVAGAGAMRQMFVNILPNCLAPLIVQASLGFSNAILDMAALGFL
HHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGVAILLTVLAFNLMGDGLRDALDPKLKQ
CCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCHHHHHCCCCCCC
>Mature Secondary Structure 
SQVTENKVIAAPVPMTPLQEFWHYFKRNKGAVVGLVYVVVMIVIAVFANFLAPYNPADQ
CCCCCCCEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
FRDSLLAPPFWQDGGSMAHLLGTDDVGRDILSRLMYGARLSLLVGCLVVVLSLILGVVLG
HHHHHCCCCCCCCCCCEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVAGYFGGVVDSIIMRVVDIMLALPSLLLALVLVAIFGPSIVNASLALTFVALPHYVRLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
RAAVLVEVNRDYVTASRVAGAGAMRQMFVNILPNCLAPLIVQASLGFSNAILDMAALGFL
HHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGVAILLTVLAFNLMGDGLRDALDPKLKQ
CCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]