Definition Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome.
Accession NC_012731
Length 5,248,520

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The map label for this gene is dppD [H]

Identifier: 238896997

GI number: 238896997

Start: 4985495

End: 4986478

Strand: Reverse

Name: dppD [H]

Synonym: KP1_5242

Alternate gene names: 238896997

Gene position: 4986478-4985495 (Counterclockwise)

Preceding gene: 238896998

Following gene: 238896996

Centisome position: 95.01

GC content: 59.45

Gene sequence:

>984_bases
ATGGCGTTATTGAATGTAGATAAATTATCGGTGCATTTCGGCGATGAAAACGCGCCGTTCCGCGCCGTAGACCGCATCAG
CTATAGCGTGAAGCAGGGTGAAGTGGTCGGTATCGTCGGAGAGTCCGGCTCCGGTAAATCTGTCAGCTCGCTGGCGATTA
TGGGGCTGATTGACTATCCCGGCCGGGTGATGGCGGACAAACTGGAATTTAACGGCCGCGATCTGCAGCGCATCTCTGAA
AAAGAGCGGCGCCAGCTGGTGGGGGCGGAAGTGGCGATGATCTTCCAGGATCCAATGACCAGCCTCAACCCGTGCTTTAC
CGTCGGCTACCAGATTATGGAAGCGATTAAGGTCCATCAGGGTGGTAATAAGCAAACCCGCCGCCAGCGGGCCATCGACC
TGCTGAACCTGGTGGGCATTCCCGATCCGGCCTCGCGGCTGGACGTCTATCCGCATCAGCTTTCCGGCGGCATGAGCCAG
CGCGTGATGATCGCGATGGCGATTGCCTGTCGGCCAAAACTACTGATTGCCGATGAACCGACCACCGCGCTGGACGTGAC
CATTCAGGCGCAAATCATTGAGCTACTGCTGGATCTGCAGCAGCAGGAGAATATGGCGCTGGTGCTGATCACCCACGACC
TGGCGCTGGTGGCGGAAGCCGCGCATAAAATTATCGTTATGTACGCGGGTCAGGTGGTGGAGACCGGTGACGCGAAAGAT
ATCTTCCGCGCGCCGCGCCATCCTTATACCCAGGCGCTGCTGCGCGCGCTGCCGGAATTCGCCCAGGATAAAGCGCGTCT
GGCCTCGCTGCCGGGCGTGGTGCCGGGGAAATATGACCGTCCCAACGGCTGCCTGCTTAATCCGCGCTGCCCCTATGCCA
CGGATAAATGCCGTAGCGAAGAGCCGGCGCTCGCGGATCTGACCGGCGGCCGCCAGTCTAAATGTCACTACCCACTCGAT
GATGCCGGGAGGCCTGGATTATGA

Upstream 100 bases:

>100_bases
CCGGGCGTGGCGATCCTGCTGACGGTGCTGGCATTTAACCTGATGGGTGACGGTCTGCGTGACGCGCTCGATCCCAAACT
GAAGCAGTAAGAGGTTCGAG

Downstream 100 bases:

>100_bases
GTACGCAAAAGGCCGCCACGCCACAACCGCTGTTGCAGGCCATTGATCTGAAAAAACACTATCCGGTGAAGAAGGGGTTA
TTCGCCCCGGAACGGCTGGT

Product: dipeptide transporter ATP-binding subunit

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MALLNVDKLSVHFGDENAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPGRVMADKLEFNGRDLQRISE
KERRQLVGAEVAMIFQDPMTSLNPCFTVGYQIMEAIKVHQGGNKQTRRQRAIDLLNLVGIPDPASRLDVYPHQLSGGMSQ
RVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLDLQQQENMALVLITHDLALVAEAAHKIIVMYAGQVVETGDAKD
IFRAPRHPYTQALLRALPEFAQDKARLASLPGVVPGKYDRPNGCLLNPRCPYATDKCRSEEPALADLTGGRQSKCHYPLD
DAGRPGL

Sequences:

>Translated_327_residues
MALLNVDKLSVHFGDENAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPGRVMADKLEFNGRDLQRISE
KERRQLVGAEVAMIFQDPMTSLNPCFTVGYQIMEAIKVHQGGNKQTRRQRAIDLLNLVGIPDPASRLDVYPHQLSGGMSQ
RVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLDLQQQENMALVLITHDLALVAEAAHKIIVMYAGQVVETGDAKD
IFRAPRHPYTQALLRALPEFAQDKARLASLPGVVPGKYDRPNGCLLNPRCPYATDKCRSEEPALADLTGGRQSKCHYPLD
DAGRPGL
>Mature_326_residues
ALLNVDKLSVHFGDENAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPGRVMADKLEFNGRDLQRISEK
ERRQLVGAEVAMIFQDPMTSLNPCFTVGYQIMEAIKVHQGGNKQTRRQRAIDLLNLVGIPDPASRLDVYPHQLSGGMSQR
VMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLDLQQQENMALVLITHDLALVAEAAHKIIVMYAGQVVETGDAKDI
FRAPRHPYTQALLRALPEFAQDKARLASLPGVVPGKYDRPNGCLLNPRCPYATDKCRSEEPALADLTGGRQSKCHYPLDD
AGRPGL

Specific function: Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system [H]

COG id: COG0444

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI42490749, Length=242, Percent_Identity=28.099173553719, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI148612844, Length=226, Percent_Identity=26.9911504424779, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI9961252, Length=247, Percent_Identity=27.9352226720648, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI9961250, Length=247, Percent_Identity=27.9352226720648, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI4505771, Length=247, Percent_Identity=27.9352226720648, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI255708477, Length=226, Percent_Identity=26.9911504424779, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI9665248, Length=242, Percent_Identity=28.9256198347107, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI21536378, Length=230, Percent_Identity=30, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1789963, Length=327, Percent_Identity=93.5779816513761, Blast_Score=627, Evalue=0.0,
Organism=Escherichia coli, GI48994883, Length=320, Percent_Identity=46.25, Blast_Score=304, Evalue=6e-84,
Organism=Escherichia coli, GI1787548, Length=330, Percent_Identity=44.5454545454545, Blast_Score=278, Evalue=3e-76,
Organism=Escherichia coli, GI145693107, Length=268, Percent_Identity=50.7462686567164, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI1787759, Length=317, Percent_Identity=41.9558359621451, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1788506, Length=258, Percent_Identity=45.7364341085271, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1787500, Length=318, Percent_Identity=37.1069182389937, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1789962, Length=317, Percent_Identity=36.2776025236593, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1787758, Length=309, Percent_Identity=35.9223300970874, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI48994997, Length=255, Percent_Identity=35.6862745098039, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1789890, Length=234, Percent_Identity=35.8974358974359, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1787547, Length=260, Percent_Identity=31.9230769230769, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1789891, Length=240, Percent_Identity=37.0833333333333, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1786398, Length=286, Percent_Identity=30.7692307692308, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787029, Length=254, Percent_Identity=32.2834645669291, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789032, Length=232, Percent_Identity=34.051724137931, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788225, Length=234, Percent_Identity=35.8974358974359, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1789672, Length=256, Percent_Identity=28.90625, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87081834, Length=223, Percent_Identity=32.2869955156951, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787089, Length=244, Percent_Identity=34.0163934426229, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87081791, Length=284, Percent_Identity=29.2253521126761, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786703, Length=216, Percent_Identity=33.3333333333333, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1787712, Length=251, Percent_Identity=29.0836653386454, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788644, Length=180, Percent_Identity=32.2222222222222, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788761, Length=242, Percent_Identity=30.1652892561983, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790162, Length=252, Percent_Identity=26.5873015873016, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787370, Length=241, Percent_Identity=27.3858921161826, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87081709, Length=236, Percent_Identity=25.8474576271186, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789873, Length=216, Percent_Identity=30.0925925925926, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788450, Length=234, Percent_Identity=26.0683760683761, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787105, Length=280, Percent_Identity=30.3571428571429, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786872, Length=219, Percent_Identity=29.6803652968037, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786563, Length=232, Percent_Identity=29.3103448275862, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789991, Length=221, Percent_Identity=27.1493212669683, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI48994943, Length=250, Percent_Identity=27.2, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786345, Length=242, Percent_Identity=26.8595041322314, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787792, Length=229, Percent_Identity=26.6375545851528, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87082267, Length=231, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790467, Length=220, Percent_Identity=27.7272727272727, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786803, Length=250, Percent_Identity=25.6, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786253, Length=223, Percent_Identity=29.1479820627803, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786319, Length=229, Percent_Identity=27.9475982532751, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787164, Length=231, Percent_Identity=29.4372294372294, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI48995001, Length=222, Percent_Identity=28.8288288288288, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786698, Length=218, Percent_Identity=28.8990825688073, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790190, Length=223, Percent_Identity=27.3542600896861, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788002, Length=227, Percent_Identity=26.431718061674, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788053, Length=197, Percent_Identity=28.4263959390863, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=229, Percent_Identity=29.6943231441048, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI193209708, Length=243, Percent_Identity=30.4526748971193, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25146777, Length=225, Percent_Identity=27.5555555555556, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193202349, Length=225, Percent_Identity=29.7777777777778, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115534520, Length=229, Percent_Identity=28.3842794759825, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17552232, Length=250, Percent_Identity=28.8, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17569143, Length=238, Percent_Identity=30.672268907563, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71984940, Length=216, Percent_Identity=28.7037037037037, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=225, Percent_Identity=29.3333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569145, Length=219, Percent_Identity=30.1369863013699, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=236, Percent_Identity=30.5084745762712, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322980, Length=269, Percent_Identity=27.8810408921933, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6324985, Length=234, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6323217, Length=230, Percent_Identity=29.1304347826087, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319856, Length=224, Percent_Identity=27.2321428571429, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641565, Length=223, Percent_Identity=30.9417040358744, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI28574744, Length=232, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574150, Length=221, Percent_Identity=23.5294117647059, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI116007328, Length=221, Percent_Identity=23.5294117647059, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI17136662, Length=218, Percent_Identity=27.5229357798165, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI19920532, Length=215, Percent_Identity=27.906976744186, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24580930, Length=215, Percent_Identity=27.906976744186, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI161076684, Length=239, Percent_Identity=25.9414225941423, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24581617, Length=239, Percent_Identity=25.9414225941423, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24581615, Length=239, Percent_Identity=25.9414225941423, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 35765; Mature: 35634

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MALLNVDKLSVHFGDENAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYP
CCEEEEEEEEEEECCCCCCHHHHHHHHHEECCCCEEEEEECCCCCCCHHHEEEEEEECCC
GRVMADKLEFNGRDLQRISEKERRQLVGAEVAMIFQDPMTSLNPCFTVGYQIMEAIKVHQ
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHC
GGNKQTRRQRAIDLLNLVGIPDPASRLDVYPHQLSGGMSQRVMIAMAIACRPKLLIADEP
CCCHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHCCCCHHHHHHHHHHHCCCEEEEECCC
TTALDVTIQAQIIELLLDLQQQENMALVLITHDLALVAEAAHKIIVMYAGQVVETGDAKD
CCEEEEEHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHEEEEEECCCEEECCCCHH
IFRAPRHPYTQALLRALPEFAQDKARLASLPGVVPGKYDRPNGCLLNPRCPYATDKCRSE
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCHHCCCC
EPALADLTGGRQSKCHYPLDDAGRPGL
CCCEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ALLNVDKLSVHFGDENAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYP
CEEEEEEEEEEECCCCCCHHHHHHHHHEECCCCEEEEEECCCCCCCHHHEEEEEEECCC
GRVMADKLEFNGRDLQRISEKERRQLVGAEVAMIFQDPMTSLNPCFTVGYQIMEAIKVHQ
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHC
GGNKQTRRQRAIDLLNLVGIPDPASRLDVYPHQLSGGMSQRVMIAMAIACRPKLLIADEP
CCCHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHCCCCHHHHHHHHHHHCCCEEEEECCC
TTALDVTIQAQIIELLLDLQQQENMALVLITHDLALVAEAAHKIIVMYAGQVVETGDAKD
CCEEEEEHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHEEEEEECCCEEECCCCHH
IFRAPRHPYTQALLRALPEFAQDKARLASLPGVVPGKYDRPNGCLLNPRCPYATDKCRSE
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCHHCCCC
EPALADLTGGRQSKCHYPLDDAGRPGL
CCCEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]