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The map label for this gene is yiaY [H]

Identifier: 238896966

GI number: 238896966

Start: 4941426

End: 4942652

Strand: Direct

Name: yiaY [H]

Synonym: KP1_5208

Alternate gene names: 238896966

Gene position: 4941426-4942652 (Clockwise)

Preceding gene: 238896964

Following gene: 238896967

Centisome position: 94.15

GC content: 66.75

Gene sequence:

>1227_bases
TTGCCAGCCAGCAACAAGGCAGAGCGCTGGATAATGTGTATAGTTGATTCCAGCCTGTTTGCCGAAAAGGAACCCGACAT
GTTGACCCCTTTTACCGTTTTGATGCCTGCAAATATTCGTTTTGGCCGTGGTCAGGCCGAGAGCGCCGCCCCCTGGCTGG
CGCAACAGGGCGGCCCAATTCTGCTGGTGCATGGCGCCCGCCCGCAGCGGGCGGCGTTTCTCCGCCAGCAGCTGGAGGCG
CTGCAGCTTGCGGTCACGACGCTGGCGATAAGTCGCGAACCCTGGCTTAGCGATATCGAGCAGGGCGTCCAGCTGGCGCG
CGAGAAAGGGATCAGAGCGGTGGTCAGCCTCGGCGGCGGCGCGGTGATTGACGCCGGTAAGGCGATTGCGGCGCTGGTCC
CCGCCGCCGGCCCGGTGATCGACTATCTGGAGGTGGTGGGAACGGGCCGTCAGCTGGAAGCCAGTCCCCTGCCGTTCGTG
GCGATCCCCACCACCGCTGGCACGGGCGCGGAGGTCACCAAAAATGCGGTGATCAACGTTCCGGAACAGCAGCGGAAAGT
GAGCCTGCGCGACGACCGAATGCTGCCTGACCTGGCGATTGTCGACCCGGCGCTAACCGACAACGCGCCGCGGAGCATCA
CCCTGAGCTCCGGCCTCGACGCCCTGACCCAGGTGATCGAGCCCTGGCTCTGCAGCCGGGCCACTCCCTTCACCGATGCT
CTCTGCCAGCAGGCGATCCCGCGGGGAATTCGCGCGCTAAAAATCCTGATGGAACAAGAGTGTCCAGCCAGCCGCGACGA
GATGGCCTGGGTCAGCCTGTGCGGCGGACTGGCGCTGGCGAACGCCGGGCTGGGGGTGATCCACGGCCTCGCCGGCCCGC
TGGGCGGCCTGAGCCGCGCCTCGCACGGCGCCCTATGCGGCAGTTTGTTGCCGTTTGGCCTGGCGCTCAATGAGTCGCAG
ATCAACGACCCTGGCCTGCGCCAGCGCGTTAACGATGTCCGCCGCTGGCTGGCCGACGGGCTGGACGTCCCTGTGGATCA
GGTCTGGGACAGTCTGCGGGAATGGAGCCATCGCGCTGGCCTTGGCACCCTGCGCGACCTCGGCGTAGCGCGCGATGCGC
TGGAACCGGCGGCGCTGGCCGCCAGCACCTCCTCATCGATGAAGGCCAACCCGGTCAGCCTGAGCGGCGAACAGCTGCTG
GAGATGCTGGAGGCGGCGTGGGAGTGA

Upstream 100 bases:

>100_bases
ACAGCACTTTCCGTACATTGATTGAAGAGCGTTTACCCAGAATTGTTAGCATCGTCAGCGATTCCTCAGCCATAAAAGAC
AGTTCATTCACTCTACTCTA

Downstream 100 bases:

>100_bases
GCGCCCCGGGATAAAATTTTGTTGCATAATGAATGCTCCGAATTTCATCTGCGCCAGGATGTACAATTTTTAATTACTTA
TCAACAGCGTACTTTGAAAT

Product: putative iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MPASNKAERWIMCIVDSSLFAEKEPDMLTPFTVLMPANIRFGRGQAESAAPWLAQQGGPILLVHGARPQRAAFLRQQLEA
LQLAVTTLAISREPWLSDIEQGVQLAREKGIRAVVSLGGGAVIDAGKAIAALVPAAGPVIDYLEVVGTGRQLEASPLPFV
AIPTTAGTGAEVTKNAVINVPEQQRKVSLRDDRMLPDLAIVDPALTDNAPRSITLSSGLDALTQVIEPWLCSRATPFTDA
LCQQAIPRGIRALKILMEQECPASRDEMAWVSLCGGLALANAGLGVIHGLAGPLGGLSRASHGALCGSLLPFGLALNESQ
INDPGLRQRVNDVRRWLADGLDVPVDQVWDSLREWSHRAGLGTLRDLGVARDALEPAALAASTSSSMKANPVSLSGEQLL
EMLEAAWE

Sequences:

>Translated_408_residues
MPASNKAERWIMCIVDSSLFAEKEPDMLTPFTVLMPANIRFGRGQAESAAPWLAQQGGPILLVHGARPQRAAFLRQQLEA
LQLAVTTLAISREPWLSDIEQGVQLAREKGIRAVVSLGGGAVIDAGKAIAALVPAAGPVIDYLEVVGTGRQLEASPLPFV
AIPTTAGTGAEVTKNAVINVPEQQRKVSLRDDRMLPDLAIVDPALTDNAPRSITLSSGLDALTQVIEPWLCSRATPFTDA
LCQQAIPRGIRALKILMEQECPASRDEMAWVSLCGGLALANAGLGVIHGLAGPLGGLSRASHGALCGSLLPFGLALNESQ
INDPGLRQRVNDVRRWLADGLDVPVDQVWDSLREWSHRAGLGTLRDLGVARDALEPAALAASTSSSMKANPVSLSGEQLL
EMLEAAWE
>Mature_407_residues
PASNKAERWIMCIVDSSLFAEKEPDMLTPFTVLMPANIRFGRGQAESAAPWLAQQGGPILLVHGARPQRAAFLRQQLEAL
QLAVTTLAISREPWLSDIEQGVQLAREKGIRAVVSLGGGAVIDAGKAIAALVPAAGPVIDYLEVVGTGRQLEASPLPFVA
IPTTAGTGAEVTKNAVINVPEQQRKVSLRDDRMLPDLAIVDPALTDNAPRSITLSSGLDALTQVIEPWLCSRATPFTDAL
CQQAIPRGIRALKILMEQECPASRDEMAWVSLCGGLALANAGLGVIHGLAGPLGGLSRASHGALCGSLLPFGLALNESQI
NDPGLRQRVNDVRRWLADGLDVPVDQVWDSLREWSHRAGLGTLRDLGVARDALEPAALAASTSSSMKANPVSLSGEQLLE
MLEAAWE

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=251, Percent_Identity=27.4900398406374, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI48994951, Length=321, Percent_Identity=30.2180685358255, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI87082107, Length=316, Percent_Identity=33.8607594936709, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1789163, Length=327, Percent_Identity=29.6636085626911, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787493, Length=318, Percent_Identity=27.9874213836478, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789386, Length=296, Percent_Identity=25, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17537053, Length=368, Percent_Identity=25.8152173913043, Blast_Score=114, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6321181, Length=383, Percent_Identity=27.9373368146214, Blast_Score=151, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24657991, Length=362, Percent_Identity=24.8618784530387, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 43286; Mature: 43155

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASNKAERWIMCIVDSSLFAEKEPDMLTPFTVLMPANIRFGRGQAESAAPWLAQQGGPI
CCCCCCCCEEEEEEECCHHHCCCCCCCCCCEEEEEECCEEECCCCCCCCCCHHHHCCCCE
LLVHGARPQRAAFLRQQLEALQLAVTTLAISREPWLSDIEQGVQLAREKGIRAVVSLGGG
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCC
AVIDAGKAIAALVPAAGPVIDYLEVVGTGRQLEASPLPFVAIPTTAGTGAEVTKNAVINV
EEEECCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCHHCCCCEECC
PEQQRKVSLRDDRMLPDLAIVDPALTDNAPRSITLSSGLDALTQVIEPWLCSRATPFTDA
CHHHHHCCCCCCCCCCCHHHCCCHHCCCCCCEEEHHCCHHHHHHHHHHHHHCCCCCHHHH
LCQQAIPRGIRALKILMEQECPASRDEMAWVSLCGGLALANAGLGVIHGLAGPLGGLSRA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHC
SHGALCGSLLPFGLALNESQINDPGLRQRVNDVRRWLADGLDVPVDQVWDSLREWSHRAG
CCHHHHHHHHHHCEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
LGTLRDLGVARDALEPAALAASTSSSMKANPVSLSGEQLLEMLEAAWE
CHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
PASNKAERWIMCIVDSSLFAEKEPDMLTPFTVLMPANIRFGRGQAESAAPWLAQQGGPI
CCCCCCCEEEEEEECCHHHCCCCCCCCCCEEEEEECCEEECCCCCCCCCCHHHHCCCCE
LLVHGARPQRAAFLRQQLEALQLAVTTLAISREPWLSDIEQGVQLAREKGIRAVVSLGGG
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCC
AVIDAGKAIAALVPAAGPVIDYLEVVGTGRQLEASPLPFVAIPTTAGTGAEVTKNAVINV
EEEECCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCHHCCCCEECC
PEQQRKVSLRDDRMLPDLAIVDPALTDNAPRSITLSSGLDALTQVIEPWLCSRATPFTDA
CHHHHHCCCCCCCCCCCHHHCCCHHCCCCCCEEEHHCCHHHHHHHHHHHHHCCCCCHHHH
LCQQAIPRGIRALKILMEQECPASRDEMAWVSLCGGLALANAGLGVIHGLAGPLGGLSRA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHC
SHGALCGSLLPFGLALNESQINDPGLRQRVNDVRRWLADGLDVPVDQVWDSLREWSHRAG
CCHHHHHHHHHHCEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
LGTLRDLGVARDALEPAALAASTSSSMKANPVSLSGEQLLEMLEAAWE
CHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]