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The map label for this gene is codA [H]

Identifier: 238896848

GI number: 238896848

Start: 4810299

End: 4811681

Strand: Reverse

Name: codA [H]

Synonym: KP1_5080

Alternate gene names: 238896848

Gene position: 4811681-4810299 (Counterclockwise)

Preceding gene: 238896852

Following gene: 238896846

Centisome position: 91.68

GC content: 58.79

Gene sequence:

>1383_bases
TTGGGTAAGCCGCGATTGGGGTTAGACAGAAAACAAGCCGTATTGAATAGAGAGGGTGATATGACAGCAGCGCCGCTTTG
GTTGATTCAGAACGTACGCCTGGCAGACCGCGACGGCCTGTGGCAAATAGCCATTGATAAGGGCCGCTTTGGCGAGATCA
CGCCGATGGGGGAGGCGCACGATGAAAGCTACGAGGTATTGAACGCTCGCGGCGGGCTAGCGATCCCGCCTTTTATCGAG
CCGCATATCCATCTGGATACCACCCAGACGGCCGGCGAGCCGAACTGGAATCAGTCCGGTACTCTGTTCGAGGGGATTGA
GCGCTGGGCGGAGCGGAAAGCGCTGCTCAGCCATGAGGACGTCAAAGCCCGGGCGTGGAAAACCCTGAAGTGGCAGATCG
CCAATGGCGTGCAGTTTGTCCGCACTCATGTCGATGTTTCCGATCCCACGTTAACGGCGCTGAAGGCGATGCTGGAGGTC
AAACAGGAGGTGGCGCCATGGGTCGAGTTACAGATTGTCGCTTTTCCACAGGAGGGGATCCTCTCTTACCCCAACGGCGA
GGCGCTGCTGGAGGAGGCCCTCAAGCTGGGGGCGGACGTCGTCGGGGCGATCCCGCATTTTGAGTTCACCCGTGAATATG
GTGTGGAATCGCTGCATATCGCCTTCCGTCTGGCGCAGCAATATGACCGCCCACTGGATATTCACTGCGATGAAATTGAT
GATGAGCAGTCGCGCTTTGTTGAAACCGTTGCCGCGCTGGCGCTGAAAGCGGGGATAGGGCCGCGGGTAACGGCCAGCCA
TACCACCGCTATGCACTCCTATAATGGCGCTTATACCTCGCGTCTGTTCCGCTTGCTTAAGCTCTCCGGCATCAACTTTG
TCGCCAATCCGCTGGTGAATATTCATCTGCAGGGCCGGTTTGACGACTACCCGAAGCGACGGGGCATTACCCGGGTGAAG
GAGCTGTTGGCGGCGGGGATCAACGTTTGCTTTGGTCATGATGACGTCTTTGACCCGTGGTACCCGCTGGGGACCGGCAA
TATGCTGCAGGTCCTGCATATGGGGCTCCATGTTTGCCAGCTGATGGGCTACCAGCAGATCAACGACGGCCTGCAGCTTA
TCACCGACAACAGCGCCCGCACGTTTGGCCTCGAGGATTACGGCATTGTCAGCGGTAACCCGGCTAACCTGATCATTCTC
CCGGCGGAGAATGGCTTTGAGGCCGTCCGCTGCCAGGTGCCGGTGCGCTGGTCAATTCGCCAGGGAAGGGTGATCGCGAC
CACCCAGCCGGCGCAAAGCTGGATCCAAACTGACCGCGGTGGCGAGGAGCTTTCTTTTATGAGGAACAGCCCCCTTGCGG
ATGCAAAGGGGCCGAAGGCTTAG

Upstream 100 bases:

>100_bases
CTTCACCTACCACTTAATGGGTATGCGTTTGATTTGTCAGTATTTTTATAAGTCATGGAAAACGCTGACTTTTCCTTTTT
GCTGATTTTGTGTACAAGAA

Downstream 100 bases:

>100_bases
TGAGACGCCGCCTGAGCGTTGTTCTGGCGATGACGGGAGACGAAGCCGAGGATAAAGCACATTACGAATACCACGGCATA
GAGGCCGTTAGCGGTGTGCA

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MGKPRLGLDRKQAVLNREGDMTAAPLWLIQNVRLADRDGLWQIAIDKGRFGEITPMGEAHDESYEVLNARGGLAIPPFIE
PHIHLDTTQTAGEPNWNQSGTLFEGIERWAERKALLSHEDVKARAWKTLKWQIANGVQFVRTHVDVSDPTLTALKAMLEV
KQEVAPWVELQIVAFPQEGILSYPNGEALLEEALKLGADVVGAIPHFEFTREYGVESLHIAFRLAQQYDRPLDIHCDEID
DEQSRFVETVAALALKAGIGPRVTASHTTAMHSYNGAYTSRLFRLLKLSGINFVANPLVNIHLQGRFDDYPKRRGITRVK
ELLAAGINVCFGHDDVFDPWYPLGTGNMLQVLHMGLHVCQLMGYQQINDGLQLITDNSARTFGLEDYGIVSGNPANLIIL
PAENGFEAVRCQVPVRWSIRQGRVIATTQPAQSWIQTDRGGEELSFMRNSPLADAKGPKA

Sequences:

>Translated_460_residues
MGKPRLGLDRKQAVLNREGDMTAAPLWLIQNVRLADRDGLWQIAIDKGRFGEITPMGEAHDESYEVLNARGGLAIPPFIE
PHIHLDTTQTAGEPNWNQSGTLFEGIERWAERKALLSHEDVKARAWKTLKWQIANGVQFVRTHVDVSDPTLTALKAMLEV
KQEVAPWVELQIVAFPQEGILSYPNGEALLEEALKLGADVVGAIPHFEFTREYGVESLHIAFRLAQQYDRPLDIHCDEID
DEQSRFVETVAALALKAGIGPRVTASHTTAMHSYNGAYTSRLFRLLKLSGINFVANPLVNIHLQGRFDDYPKRRGITRVK
ELLAAGINVCFGHDDVFDPWYPLGTGNMLQVLHMGLHVCQLMGYQQINDGLQLITDNSARTFGLEDYGIVSGNPANLIIL
PAENGFEAVRCQVPVRWSIRQGRVIATTQPAQSWIQTDRGGEELSFMRNSPLADAKGPKA
>Mature_459_residues
GKPRLGLDRKQAVLNREGDMTAAPLWLIQNVRLADRDGLWQIAIDKGRFGEITPMGEAHDESYEVLNARGGLAIPPFIEP
HIHLDTTQTAGEPNWNQSGTLFEGIERWAERKALLSHEDVKARAWKTLKWQIANGVQFVRTHVDVSDPTLTALKAMLEVK
QEVAPWVELQIVAFPQEGILSYPNGEALLEEALKLGADVVGAIPHFEFTREYGVESLHIAFRLAQQYDRPLDIHCDEIDD
EQSRFVETVAALALKAGIGPRVTASHTTAMHSYNGAYTSRLFRLLKLSGINFVANPLVNIHLQGRFDDYPKRRGITRVKE
LLAAGINVCFGHDDVFDPWYPLGTGNMLQVLHMGLHVCQLMGYQQINDGLQLITDNSARTFGLEDYGIVSGNPANLIILP
AENGFEAVRCQVPVRWSIRQGRVIATTQPAQSWIQTDRGGEELSFMRNSPLADAKGPKA

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=415, Percent_Identity=78.7951807228916, Blast_Score=685, Evalue=0.0,
Organism=Escherichia coli, GI1786517, Length=298, Percent_Identity=27.5167785234899, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 51209; Mature: 51078

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKPRLGLDRKQAVLNREGDMTAAPLWLIQNVRLADRDGLWQIAIDKGRFGEITPMGEAH
CCCCCCCCCHHHHHHCCCCCCCCCHHHHHCCCEEECCCCEEEEEECCCCCCCCCCCCCCC
DESYEVLNARGGLAIPPFIEPHIHLDTTQTAGEPNWNQSGTLFEGIERWAERKALLSHED
CCHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
VKARAWKTLKWQIANGVQFVRTHVDVSDPTLTALKAMLEVKQEVAPWVELQIVAFPQEGI
HHHHHHHEEEEEECCCEEEEHEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCC
LSYPNGEALLEEALKLGADVVGAIPHFEFTREYGVESLHIAFRLAQQYDRPLDIHCDEID
CCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEEECCCCC
DEQSRFVETVAALALKAGIGPRVTASHTTAMHSYNGAYTSRLFRLLKLSGINFVANPLVN
CHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCEEE
IHLQGRFDDYPKRRGITRVKELLAAGINVCFGHDDVFDPWYPLGTGNMLQVLHMGLHVCQ
EEEECCCCCCHHHCCHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LMGYQQINDGLQLITDNSARTFGLEDYGIVSGNPANLIILPAENGFEAVRCQVPVRWSIR
HHCHHHHCCCEEEEECCCCEEECCCCCCEECCCCCCEEEEECCCCCCEEEEEECEEEECC
QGRVIATTQPAQSWIQTDRGGEELSFMRNSPLADAKGPKA
CCEEEEECCHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
GKPRLGLDRKQAVLNREGDMTAAPLWLIQNVRLADRDGLWQIAIDKGRFGEITPMGEAH
CCCCCCCCHHHHHHCCCCCCCCCHHHHHCCCEEECCCCEEEEEECCCCCCCCCCCCCCC
DESYEVLNARGGLAIPPFIEPHIHLDTTQTAGEPNWNQSGTLFEGIERWAERKALLSHED
CCHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
VKARAWKTLKWQIANGVQFVRTHVDVSDPTLTALKAMLEVKQEVAPWVELQIVAFPQEGI
HHHHHHHEEEEEECCCEEEEHEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCC
LSYPNGEALLEEALKLGADVVGAIPHFEFTREYGVESLHIAFRLAQQYDRPLDIHCDEID
CCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEEECCCCC
DEQSRFVETVAALALKAGIGPRVTASHTTAMHSYNGAYTSRLFRLLKLSGINFVANPLVN
CHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCEEE
IHLQGRFDDYPKRRGITRVKELLAAGINVCFGHDDVFDPWYPLGTGNMLQVLHMGLHVCQ
EEEECCCCCCHHHCCHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LMGYQQINDGLQLITDNSARTFGLEDYGIVSGNPANLIILPAENGFEAVRCQVPVRWSIR
HHCHHHHCCCEEEEECCCCEEECCCCCCEECCCCCCEEEEECCCCCCEEEEEECEEEECC
QGRVIATTQPAQSWIQTDRGGEELSFMRNSPLADAKGPKA
CCEEEEECCHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]