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The map label for this gene is argD [H]

Identifier: 238896842

GI number: 238896842

Start: 4805496

End: 4806716

Strand: Reverse

Name: argD [H]

Synonym: KP1_5073

Alternate gene names: 238896842

Gene position: 4806716-4805496 (Counterclockwise)

Preceding gene: 238896843

Following gene: 238896839

Centisome position: 91.58

GC content: 60.61

Gene sequence:

>1221_bases
ATGGCAACTGAACAACCGGCAATCACCCGCGCCACATTCGATGAAGTTATTTTGCCAATTTATGCACCGGCAGAATTCAT
CCCGGTGAAGGGGAAAGGCAGCCGCGTCTGGGATCAGCAGGGGAAAGAGTATATCGATTTCGCCGGCGGTATCGCGGTGA
CGGCGCTTGGCCATTGCCATCCGGCGCTGGTGGCGGCGCTGCATCAGCAGGGCGAAACGCTGTGGCACACCAGCAACGTC
TTTACCAATGAGCCGGCGCTGCGTCTGGGACGTAAACTTGTCGAGGCTACCTTCGCCGAGCGCGTGGTGTTTATGAACTC
CGGCACCGAAGCCAATGAAACGGCCTTTAAGCTGGCGCGTCACTATGCGGTGACCCGCCATAGCCCGTATAAAACCAAAA
TCATCGCCTTCCATAATGCCTTTCATGGCCGCTCCCTGTTTACCGTTTCCGTCGGCGGTCAGCCGAAGTATTCCGATGGT
TTCGGCCCAAAACCGGCGGATATTGTCCATGTTCCCTTCAACGATCTGCAGGCGGTAAAAGCGGTGATGGATGACCACAC
CTGCGCGGTGGTGGTGGAGCCGATTCAGGGCGAAGGCGGCGTGACGGCGGCCACGCCGGCTTTCCTGCAGGGACTGCGCG
AGCTGTGCGATCAGCACCAGGCGCTGCTCGTCTTTGATGAAGTACAGTGCGGTATGGGGCGTACCGGATCGCTGTTCGCC
TATATGCACTACGGCGTGACCCCGGATATTCTGACCAGCGCCAAAGCGCTGGGCGGCGGCTTCCCGGTCAGCGCCATGCT
GACCACCCACGAGATCGCCAGCGCCTTCCATGCGGGCTCCCATGGCTCAACCTACGGCGGCAACCCGCTGGCCTGCGCGG
TCGCCAACGCCGCCTTCGATCTGATCAATACCCCGGCGGTGCTGGATGGCGTGAGCGCGAAGCGCGAACTGTTCGTCAAA
CACCTGCAGCGGCTGGATGCCGAGTTTGATCTGTTCAGTGATATACGCGGGATGGGCCTGCTGATCGGCGCGGAACTCAA
GCCGCAGCACAAAGGCCGCGCGCGTGATTTCCTCTATGCCGCGGCCGACGCCGGCGTCATGGTGCTCAACGCCGGGCCGG
ACGTGATGCGTTTTGTTCCCTCGCTGATCATCGACGAGCAGGATATTACTGAAGGGATGGCGCGCTTTGCCCAGGCGGTG
GCAAAGGTGATTAACGGTTGA

Upstream 100 bases:

>100_bases
GAAACGGTGATTTTCAGTTGCTATTGACTGATTTTTTATGCATATTTTGTGATTAGATTATCATAATCGCATCTGCGTAA
CGAAGAGGGATGGGCAAGAC

Downstream 100 bases:

>100_bases
TCTTCCGCAGCCAGATGCCATGGTGCGGCCGCTGACGCCATGCCACTGACGAAATGGTGTGCATGGTGTTCAGATGGCCC
AGAATGCGTTGCAGATGCTG

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT; DapATase; Succinyldiaminopimelate transferase [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MATEQPAITRATFDEVILPIYAPAEFIPVKGKGSRVWDQQGKEYIDFAGGIAVTALGHCHPALVAALHQQGETLWHTSNV
FTNEPALRLGRKLVEATFAERVVFMNSGTEANETAFKLARHYAVTRHSPYKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
FGPKPADIVHVPFNDLQAVKAVMDDHTCAVVVEPIQGEGGVTAATPAFLQGLRELCDQHQALLVFDEVQCGMGRTGSLFA
YMHYGVTPDILTSAKALGGGFPVSAMLTTHEIASAFHAGSHGSTYGGNPLACAVANAAFDLINTPAVLDGVSAKRELFVK
HLQRLDAEFDLFSDIRGMGLLIGAELKPQHKGRARDFLYAAADAGVMVLNAGPDVMRFVPSLIIDEQDITEGMARFAQAV
AKVING

Sequences:

>Translated_406_residues
MATEQPAITRATFDEVILPIYAPAEFIPVKGKGSRVWDQQGKEYIDFAGGIAVTALGHCHPALVAALHQQGETLWHTSNV
FTNEPALRLGRKLVEATFAERVVFMNSGTEANETAFKLARHYAVTRHSPYKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
FGPKPADIVHVPFNDLQAVKAVMDDHTCAVVVEPIQGEGGVTAATPAFLQGLRELCDQHQALLVFDEVQCGMGRTGSLFA
YMHYGVTPDILTSAKALGGGFPVSAMLTTHEIASAFHAGSHGSTYGGNPLACAVANAAFDLINTPAVLDGVSAKRELFVK
HLQRLDAEFDLFSDIRGMGLLIGAELKPQHKGRARDFLYAAADAGVMVLNAGPDVMRFVPSLIIDEQDITEGMARFAQAV
AKVING
>Mature_405_residues
ATEQPAITRATFDEVILPIYAPAEFIPVKGKGSRVWDQQGKEYIDFAGGIAVTALGHCHPALVAALHQQGETLWHTSNVF
TNEPALRLGRKLVEATFAERVVFMNSGTEANETAFKLARHYAVTRHSPYKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGF
GPKPADIVHVPFNDLQAVKAVMDDHTCAVVVEPIQGEGGVTAATPAFLQGLRELCDQHQALLVFDEVQCGMGRTGSLFAY
MHYGVTPDILTSAKALGGGFPVSAMLTTHEIASAFHAGSHGSTYGGNPLACAVANAAFDLINTPAVLDGVSAKRELFVKH
LQRLDAEFDLFSDIRGMGLLIGAELKPQHKGRARDFLYAAADAGVMVLNAGPDVMRFVPSLIIDEQDITEGMARFAQAVA
KVING

Specific function: Involved in both the arginine and lysine biosynthetic pathways [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=377, Percent_Identity=37.4005305039788, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI284507298, Length=300, Percent_Identity=38.3333333333333, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI13994255, Length=425, Percent_Identity=29.1764705882353, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI37574042, Length=402, Percent_Identity=29.8507462686567, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI226442709, Length=375, Percent_Identity=30.4, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI226442705, Length=402, Percent_Identity=28.8557213930348, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI24119277, Length=405, Percent_Identity=27.4074074074074, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI188536080, Length=419, Percent_Identity=21.9570405727924, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI38679950, Length=419, Percent_Identity=21.9570405727924, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI38679946, Length=419, Percent_Identity=21.9570405727924, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1789759, Length=404, Percent_Identity=88.1188118811881, Blast_Score=750, Evalue=0.0,
Organism=Escherichia coli, GI1788044, Length=401, Percent_Identity=60.3491271820449, Blast_Score=514, Evalue=1e-147,
Organism=Escherichia coli, GI1789016, Length=411, Percent_Identity=36.0097323600973, Blast_Score=231, Evalue=4e-62,
Organism=Escherichia coli, GI145693181, Length=392, Percent_Identity=34.9489795918367, Blast_Score=197, Evalue=8e-52,
Organism=Escherichia coli, GI1787560, Length=404, Percent_Identity=31.9306930693069, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1786991, Length=299, Percent_Identity=33.1103678929766, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1786349, Length=296, Percent_Identity=32.7702702702703, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=375, Percent_Identity=36, Blast_Score=241, Evalue=5e-64,
Organism=Caenorhabditis elegans, GI32564660, Length=433, Percent_Identity=28.8683602771363, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI25144274, Length=260, Percent_Identity=36.5384615384615, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI71992977, Length=429, Percent_Identity=28.9044289044289, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17541228, Length=427, Percent_Identity=25.5269320843091, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71981843, Length=164, Percent_Identity=32.9268292682927, Blast_Score=91, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6324432, Length=397, Percent_Identity=40.0503778337531, Blast_Score=297, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6323470, Length=401, Percent_Identity=34.1645885286783, Blast_Score=224, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6324386, Length=314, Percent_Identity=28.6624203821656, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321456, Length=441, Percent_Identity=25.3968253968254, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21357415, Length=378, Percent_Identity=36.5079365079365, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI28574759, Length=421, Percent_Identity=29.9287410926366, Blast_Score=178, Evalue=6e-45,
Organism=Drosophila melanogaster, GI161085790, Length=416, Percent_Identity=29.8076923076923, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21356575, Length=417, Percent_Identity=30.4556354916067, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI281366494, Length=434, Percent_Identity=23.2718894009217, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24667139, Length=434, Percent_Identity=23.2718894009217, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24667143, Length=434, Percent_Identity=23.2718894009217, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11; =2.6.1.17 [H]

Molecular weight: Translated: 43584; Mature: 43453

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATEQPAITRATFDEVILPIYAPAEFIPVKGKGSRVWDQQGKEYIDFAGGIAVTALGHCH
CCCCCCCHHHHHHHHHHEEEECCCEEEEECCCCCCCHHHCCCHHHHHCCCHHHHHHHCHH
PALVAALHQQGETLWHTSNVFTNEPALRLGRKLVEATFAERVVFMNSGTEANETAFKLAR
HHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHH
HYAVTRHSPYKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGFGPKPADIVHVPFNDLQAVK
HHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHH
AVMDDHTCAVVVEPIQGEGGVTAATPAFLQGLRELCDQHQALLVFDEVQCGMGRTGSLFA
HHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEHHCCCCCCCCEEE
YMHYGVTPDILTSAKALGGGFPVSAMLTTHEIASAFHAGSHGSTYGGNPLACAVANAAFD
EEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHH
LINTPAVLDGVSAKRELFVKHLQRLDAEFDLFSDIRGMGLLIGAELKPQHKGRARDFLYA
HHCCCHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCCCCCCCCCHHHHEEE
AADAGVMVLNAGPDVMRFVPSLIIDEQDITEGMARFAQAVAKVING
ECCCCEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATEQPAITRATFDEVILPIYAPAEFIPVKGKGSRVWDQQGKEYIDFAGGIAVTALGHCH
CCCCCCHHHHHHHHHHEEEECCCEEEEECCCCCCCHHHCCCHHHHHCCCHHHHHHHCHH
PALVAALHQQGETLWHTSNVFTNEPALRLGRKLVEATFAERVVFMNSGTEANETAFKLAR
HHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHH
HYAVTRHSPYKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGFGPKPADIVHVPFNDLQAVK
HHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHH
AVMDDHTCAVVVEPIQGEGGVTAATPAFLQGLRELCDQHQALLVFDEVQCGMGRTGSLFA
HHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEHHCCCCCCCCEEE
YMHYGVTPDILTSAKALGGGFPVSAMLTTHEIASAFHAGSHGSTYGGNPLACAVANAAFD
EEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHH
LINTPAVLDGVSAKRELFVKHLQRLDAEFDLFSDIRGMGLLIGAELKPQHKGRARDFLYA
HHCCCHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCCCCCCCCCHHHHEEE
AADAGVMVLNAGPDVMRFVPSLIIDEQDITEGMARFAQAVAKVING
ECCCCEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]