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The map label for this gene is pabA [H]

Identifier: 238896843

GI number: 238896843

Start: 4806807

End: 4807370

Strand: Reverse

Name: pabA [H]

Synonym: KP1_5074

Alternate gene names: 238896843

Gene position: 4807370-4806807 (Counterclockwise)

Preceding gene: 238896844

Following gene: 238896842

Centisome position: 91.59

GC content: 59.22

Gene sequence:

>564_bases
ATGATCCTGCTTATCGATAACTATGACTCTTTCACCTGGAATCTGTATCAGTACTTCTGCGAACTGGGGGCGGAAGTACT
GGTCAGGCGCAACGATGCGTTGACGCTGGAGGAGATAGCGGCGCTGGCGCCGGAGAAAATCGTGATCTCGCCAGGCCCCT
GCACGCCGGATGAGGCGGGGATTTCCCTCGCGGTTATCCGCCACTATGCCGGAAAAACGCCGCTGCTGGGCGTCTGTCTC
GGGCATCAGGCGATCGCCCAGGCGTTTGGCGCGACTATCGTGCGGGCGGCCCAGGTCATGCATGGCAAAACCTCGCTTAT
CGAGCATAACGGCGAAGGGGTGTTTCAGGGGCTGAATAATCCCCTGACGGTGACCCGCTATCACTCGCTGGTGATTGACC
CGCCGACGCTCCCGTCCGAGTTTAACGTCACTGCCCGCAGCGCCAGCGGTGAGATTATGGGGATCCGTCACCGCGAATGG
GATCTCGAGGGCGTGCAGTTTCATCCGGAAAGCATCCTCAGCGAGCAGGGCCATCAATTGCTGGCCAACTTTTTGAAACG
GTGA

Upstream 100 bases:

>100_bases
TGGGCGATCTGGCCCCGCTGGTGGCGATCTTTCGCAAAGTGGTAAGCGAAGCGCGGGAATCTGAGTAGAATAGCCCGGTT
TTGATTGTTCCGGAGCCGCT

Downstream 100 bases:

>100_bases
TTTTCAGTTGCTATTGACTGATTTTTTATGCATATTTTGTGATTAGATTATCATAATCGCATCTGCGTAACGAAGAGGGA
TGGGCAAGACATGGCAACTG

Product: para-aminobenzoate synthase component II

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MILLIDNYDSFTWNLYQYFCELGAEVLVRRNDALTLEEIAALAPEKIVISPGPCTPDEAGISLAVIRHYAGKTPLLGVCL
GHQAIAQAFGATIVRAAQVMHGKTSLIEHNGEGVFQGLNNPLTVTRYHSLVIDPPTLPSEFNVTARSASGEIMGIRHREW
DLEGVQFHPESILSEQGHQLLANFLKR

Sequences:

>Translated_187_residues
MILLIDNYDSFTWNLYQYFCELGAEVLVRRNDALTLEEIAALAPEKIVISPGPCTPDEAGISLAVIRHYAGKTPLLGVCL
GHQAIAQAFGATIVRAAQVMHGKTSLIEHNGEGVFQGLNNPLTVTRYHSLVIDPPTLPSEFNVTARSASGEIMGIRHREW
DLEGVQFHPESILSEQGHQLLANFLKR
>Mature_187_residues
MILLIDNYDSFTWNLYQYFCELGAEVLVRRNDALTLEEIAALAPEKIVISPGPCTPDEAGISLAVIRHYAGKTPLLGVCL
GHQAIAQAFGATIVRAAQVMHGKTSLIEHNGEGVFQGLNNPLTVTRYHSLVIDPPTLPSEFNVTARSASGEIMGIRHREW
DLEGVQFHPESILSEQGHQLLANFLKR

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=82.3529411764706, Blast_Score=327, Evalue=2e-91,
Organism=Escherichia coli, GI1787517, Length=187, Percent_Identity=44.3850267379679, Blast_Score=154, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6322638, Length=185, Percent_Identity=50.8108108108108, Blast_Score=209, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=27.9620853080569, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 20572; Mature: 20572

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00442 GATASE_TYPE_I ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLIDNYDSFTWNLYQYFCELGAEVLVRRNDALTLEEIAALAPEKIVISPGPCTPDEAG
CEEEEECCCCCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHCCCCEEEECCCCCCCCCCC
ISLAVIRHYAGKTPLLGVCLGHQAIAQAFGATIVRAAQVMHGKTSLIEHNGEGVFQGLNN
CCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCCC
PLTVTRYHSLVIDPPTLPSEFNVTARSASGEIMGIRHREWDLEGVQFHPESILSEQGHQL
CEEEEEEEEEEECCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCEECHHHHHHHHHHHH
LANFLKR
HHHHHCC
>Mature Secondary Structure
MILLIDNYDSFTWNLYQYFCELGAEVLVRRNDALTLEEIAALAPEKIVISPGPCTPDEAG
CEEEEECCCCCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHCCCCEEEECCCCCCCCCCC
ISLAVIRHYAGKTPLLGVCLGHQAIAQAFGATIVRAAQVMHGKTSLIEHNGEGVFQGLNN
CCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCCC
PLTVTRYHSLVIDPPTLPSEFNVTARSASGEIMGIRHREWDLEGVQFHPESILSEQGHQL
CEEEEEEEEEEECCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCEECHHHHHHHHHHHH
LANFLKR
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3894673 [H]