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The map label for this gene is uxuA [H]

Identifier: 238896717

GI number: 238896717

Start: 4692270

End: 4693334

Strand: Reverse

Name: uxuA [H]

Synonym: KP1_4932

Alternate gene names: 238896717

Gene position: 4693334-4692270 (Counterclockwise)

Preceding gene: 238896720

Following gene: 238896716

Centisome position: 89.42

GC content: 55.68

Gene sequence:

>1065_bases
ATGCAGATGACAATGCGCTGGTTTGGACCAGAGGAAGACAAGATTTCATTAGAACATATTCGCCAGGTGCCTGGCGTTGA
GGGGGTGGTCGGCGCGCTCTACGACGTCGCGGTGGGCGAAGTATGGCCGGTGGATAAAATTGAGCGTCTGGTCGGTCAGG
CCCATGCCGCAGGCCTGAAAATGGAGGTGATCGAGAGCGTCAACATCCATGACGACATCAAAATCGGCCTACCTACCCGT
GACCGCTATATTGCCAACTACCAGCAGACCATCCGCAACCTTGCCCGCTTTGGCGTTAAAGTCATCTGCTATAACTTCAT
GCCGGTTTTCGACTGGATGAAGACGGATATGAACTACGTCCTGCCGGATGGCTCGCTGACGATGGCGTTTGAGAAGAAAG
ATATCGATAAGCGGCTGGAAGACGTGGTGAAGGAGGTGCTTGAGAATTCAAACGGCTTCGCCTTGCCGGGCTGGGAGCCG
GAACGGCTGGCGGAGGTGCAGACCCTGTTTGCCAAATATAGCGCGGTGGATGATCAGAAGCTGCGGGAGAACCTGGTTTA
TTTTCTGCAGGCGGTGATCCCGGTTTGCGAAGAGGTTGGGGTGAAAATGGCGATCCACCCGGACGACCCGCCGTACTCCA
TTTTTGGCCTGCCGCGGGTGGTCAAAAACCGCGACGATCTGGACTGGATCTGCCGGGCCGTCGATTCACCCGCCAACGGC
ATTACGCTCTGCACCGGCTCGATTGCCGAAGATCCTGATAATGACGTGTACGCCATCCTGGCCGAATTTACGCGGCGTAA
GCGAATTCATTTTGCCCACGTCCGCAATATAAAGCTGATGCAGGATAAAGACTTTTACGAGTGCGCCCATCCGTCAGAGT
ACGGCTCCCTGGATATGTACAAAGTGATGCAAGCGCTGTATGACAACGGATTCGACGGCTATATTCGCCCGGATCATGGT
CGCTTTATCTGGGGAGAGACCGGACGGCCGGGCTATGGCCTGTTCGACCGCGCCCTCGGCGTGACCTACCTGAAAGGACT
CTGGGAGGCGTTAAGCAAGCGTTAA

Upstream 100 bases:

>100_bases
GGCAGGAATGTGATCGCTATCACGACAGCCAACGCTCAATCATCTATGATTACTGGTATGGTAGTAGGGTAAATTAAACT
AAGTTGAGCAGGTGAAGACA

Downstream 100 bases:

>100_bases
TCCCTCTTCTGATCCCCCTCTTTTGCGGCTGGTTCGCCTCTGCGGCCGGCCGCCGTATCGACTCCTGCCCGCATTTTTTG
CACAACTTACAGCGCATTGC

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MQMTMRWFGPEEDKISLEHIRQVPGVEGVVGALYDVAVGEVWPVDKIERLVGQAHAAGLKMEVIESVNIHDDIKIGLPTR
DRYIANYQQTIRNLARFGVKVICYNFMPVFDWMKTDMNYVLPDGSLTMAFEKKDIDKRLEDVVKEVLENSNGFALPGWEP
ERLAEVQTLFAKYSAVDDQKLRENLVYFLQAVIPVCEEVGVKMAIHPDDPPYSIFGLPRVVKNRDDLDWICRAVDSPANG
ITLCTGSIAEDPDNDVYAILAEFTRRKRIHFAHVRNIKLMQDKDFYECAHPSEYGSLDMYKVMQALYDNGFDGYIRPDHG
RFIWGETGRPGYGLFDRALGVTYLKGLWEALSKR

Sequences:

>Translated_354_residues
MQMTMRWFGPEEDKISLEHIRQVPGVEGVVGALYDVAVGEVWPVDKIERLVGQAHAAGLKMEVIESVNIHDDIKIGLPTR
DRYIANYQQTIRNLARFGVKVICYNFMPVFDWMKTDMNYVLPDGSLTMAFEKKDIDKRLEDVVKEVLENSNGFALPGWEP
ERLAEVQTLFAKYSAVDDQKLRENLVYFLQAVIPVCEEVGVKMAIHPDDPPYSIFGLPRVVKNRDDLDWICRAVDSPANG
ITLCTGSIAEDPDNDVYAILAEFTRRKRIHFAHVRNIKLMQDKDFYECAHPSEYGSLDMYKVMQALYDNGFDGYIRPDHG
RFIWGETGRPGYGLFDRALGVTYLKGLWEALSKR
>Mature_354_residues
MQMTMRWFGPEEDKISLEHIRQVPGVEGVVGALYDVAVGEVWPVDKIERLVGQAHAAGLKMEVIESVNIHDDIKIGLPTR
DRYIANYQQTIRNLARFGVKVICYNFMPVFDWMKTDMNYVLPDGSLTMAFEKKDIDKRLEDVVKEVLENSNGFALPGWEP
ERLAEVQTLFAKYSAVDDQKLRENLVYFLQAVIPVCEEVGVKMAIHPDDPPYSIFGLPRVVKNRDDLDWICRAVDSPANG
ITLCTGSIAEDPDNDVYAILAEFTRRKRIHFAHVRNIKLMQDKDFYECAHPSEYGSLDMYKVMQALYDNGFDGYIRPDHG
RFIWGETGRPGYGLFDRALGVTYLKGLWEALSKR

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1790778, Length=395, Percent_Identity=38.7341772151899, Blast_Score=258, Evalue=5e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004628
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03786 UxuA [H]

EC number: =4.2.1.8 [H]

Molecular weight: Translated: 40481; Mature: 40481

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMTMRWFGPEEDKISLEHIRQVPGVEGVVGALYDVAVGEVWPVDKIERLVGQAHAAGLK
CCCEEECCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCH
MEVIESVNIHDDIKIGLPTRDRYIANYQQTIRNLARFGVKVICYNFMPVFDWMKTDMNYV
HHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LPDGSLTMAFEKKDIDKRLEDVVKEVLENSNGFALPGWEPERLAEVQTLFAKYSAVDDQK
ECCCCEEEEECHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHCCCHHH
LRENLVYFLQAVIPVCEEVGVKMAIHPDDPPYSIFGLPRVVKNRDDLDWICRAVDSPANG
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCHHHCCCCCHHHHHHHHCCCCCC
ITLCTGSIAEDPDNDVYAILAEFTRRKRIHFAHVRNIKLMQDKDFYECAHPSEYGSLDMY
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHCCCCCCCCCCHHH
KVMQALYDNGFDGYIRPDHGRFIWGETGRPGYGLFDRALGVTYLKGLWEALSKR
HHHHHHHCCCCCCCEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQMTMRWFGPEEDKISLEHIRQVPGVEGVVGALYDVAVGEVWPVDKIERLVGQAHAAGLK
CCCEEECCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCH
MEVIESVNIHDDIKIGLPTRDRYIANYQQTIRNLARFGVKVICYNFMPVFDWMKTDMNYV
HHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LPDGSLTMAFEKKDIDKRLEDVVKEVLENSNGFALPGWEPERLAEVQTLFAKYSAVDDQK
ECCCCEEEEECHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHCCCHHH
LRENLVYFLQAVIPVCEEVGVKMAIHPDDPPYSIFGLPRVVKNRDDLDWICRAVDSPANG
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCHHHCCCCCHHHHHHHHCCCCCC
ITLCTGSIAEDPDNDVYAILAEFTRRKRIHFAHVRNIKLMQDKDFYECAHPSEYGSLDMY
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHCCCCCCCCCCHHH
KVMQALYDNGFDGYIRPDHGRFIWGETGRPGYGLFDRALGVTYLKGLWEALSKR
HHHHHHHCCCCCCCEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]