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The map label for this gene is dhaK [H]

Identifier: 238896594

GI number: 238896594

Start: 4574923

End: 4576572

Strand: Direct

Name: dhaK [H]

Synonym: KP1_4795

Alternate gene names: 238896594

Gene position: 4574923-4576572 (Clockwise)

Preceding gene: 238896593

Following gene: 238896596

Centisome position: 87.17

GC content: 64.42

Gene sequence:

>1650_bases
ATGTCTCAATTCTTTTTTAACCAGCGCGCCAGCCTCGTCAACGATGTGATTGAGGGTACCATTATCGCCAGCCCGTGGAA
TAACCTCGCCCGTCTGGAGAGCGACCCGGCGATCCGGGTGGTGGTCCGTCGCGATCTGAATAAAAACAACGTGGCGGTGA
TCTCCGGCGGCGGCGCCGGCCATGAACCGGCGCACGTCGGCTTTATTGGTAAAGGCATGCTGACCGCCGCGGTCTGCGGC
GATCTGTTCGCCTCGCCGAGCGTCGACGCGGTGCTCACCGCCATTCAGGCAGTGACCGGCGAGGCGGGCTGCCTGCTGAT
CGTCAAAAACTACACCGGCGATCGGCTTAACTTCGGTCTGGCGGCGGAGAAAGCGCGCCGACTCGGCTACAACGTGGAGA
TGCTGATCGTCGGCGACGATATTTCGCTGCCGGATAACAAACAGCCGCGCGGCATCGCCGGGACCATTCTGGTGCATAAA
GTGGCTGGCTATTTCGCCGAGCGCGGCTTCAACCTCGCCACCGTCCTGCGTGAAGCGCAATACGCCGCCAGCCATACCGC
CAGCATCGGGGTGGCGCTGGCCAGCTGCCACCTGCCGCAGGAAGCCGACAGCGCGCCGCGCCATCAGGCCGGTCACGCCG
AGCTGGGAATGGGCATCCACGGAGAGCCGGGCGCCTCGACGATCGCCACGCAAAACAGTGCGGAAATCGTTAACCTGATG
GTGGAAAAACTGACCGCCGCCCTACCGGAAACCGGCCGCCTGGCGGTGATGCTCAATAACCTCGGCGGCGTGTCGGTGGC
TGAGATGGCGATCCTGACCCGCGAGCTGGCCAACACCCCGCTGCAGGCGCGCATTGACTGGTTAATAGGCCCGGCCTCGC
TGGTGACGGCGCTGGATATGAAAGGCTTCTCGCTGACCACCATCGTGCTGGAGGAGAGTATTGAGAAAGCGCTGCTTTCG
GATGTGGAAACCGCCAGCTGGCAGAAGCCGGTGCAGCCGCGGACTATCAACGTCGTGCCGTCCACCCTCGACAGCGCCCG
GGTGGATTTTACGCCCTCGGCCAACCCACAGGTGGGCGATTACGTGGCGCAGGTGACCGGCGCCCTCATCGATCTTGAAG
AACATCTCAACGCGCTGGATGCCAAAGTAGGCGACGGCGATACCGGCTCCACCTTCGCCGCCGGGGCGCGTGAAATTGCC
GAGCGGCTCGAGCGTCAGCAGCTGCCGCTGAACGATCTGCCAACGCTCTTCGCGCTGATCGGCGAACGCCTGACGGTGGT
GATGGGCGGCTCCAGCGGGGTATTGATGTCTATCTTCTTCACCGCTGCCGGGCAGAAGCTGGGGCAAGGCGCCAGCGTGG
CCGAGGCGCTGAACGCCGGTCTGGAACAGATGAAGTTTTACGGCGGCGCCGATGAGGGAGACCGGACGATGATCGACGCT
CTGCAGCCGGCGCTGGCGGCGCTGCTGGCCGAACCGGAGAATCTGCAGGCCGCTTTCGCCGCGGCGCAGGCCGGGGCGGA
TCGCACCTGCCAGTCAAGCAAAGCCGGCGCCGGACGCGCGTCCTATCTCAACAGCGATAGCCTGCTCGGCAACATGGACC
CCGGCGCCCACGCGGTGGCGATGGTGTTTAAGGCGCTGGCGGAACGCTAA

Upstream 100 bases:

>100_bases
CCACCAGCGCCTTATCCGTGACTAAAATTCACGTTGACCGTTACCGCTCCGGGGGCCTGCCTCCGGAGGGTGAGTTTTCG
CTTACTCTTCAGGAACCACT

Downstream 100 bases:

>100_bases
GCCTTCCCCGGTGGCGCTGCGCTTACCGGGGCGACGTAACACCGCCGAATAGCAGGTCGGGTAAGGCGTAAGCCGCCACC
CGACAAAAAACGGCACCGCC

Product: putative dihydroxyacetone kinase

Products: NA

Alternate protein names: DHA kinase; Glycerone kinase [H]

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MSQFFFNQRASLVNDVIEGTIIASPWNNLARLESDPAIRVVVRRDLNKNNVAVISGGGAGHEPAHVGFIGKGMLTAAVCG
DLFASPSVDAVLTAIQAVTGEAGCLLIVKNYTGDRLNFGLAAEKARRLGYNVEMLIVGDDISLPDNKQPRGIAGTILVHK
VAGYFAERGFNLATVLREAQYAASHTASIGVALASCHLPQEADSAPRHQAGHAELGMGIHGEPGASTIATQNSAEIVNLM
VEKLTAALPETGRLAVMLNNLGGVSVAEMAILTRELANTPLQARIDWLIGPASLVTALDMKGFSLTTIVLEESIEKALLS
DVETASWQKPVQPRTINVVPSTLDSARVDFTPSANPQVGDYVAQVTGALIDLEEHLNALDAKVGDGDTGSTFAAGAREIA
ERLERQQLPLNDLPTLFALIGERLTVVMGGSSGVLMSIFFTAAGQKLGQGASVAEALNAGLEQMKFYGGADEGDRTMIDA
LQPALAALLAEPENLQAAFAAAQAGADRTCQSSKAGAGRASYLNSDSLLGNMDPGAHAVAMVFKALAER

Sequences:

>Translated_549_residues
MSQFFFNQRASLVNDVIEGTIIASPWNNLARLESDPAIRVVVRRDLNKNNVAVISGGGAGHEPAHVGFIGKGMLTAAVCG
DLFASPSVDAVLTAIQAVTGEAGCLLIVKNYTGDRLNFGLAAEKARRLGYNVEMLIVGDDISLPDNKQPRGIAGTILVHK
VAGYFAERGFNLATVLREAQYAASHTASIGVALASCHLPQEADSAPRHQAGHAELGMGIHGEPGASTIATQNSAEIVNLM
VEKLTAALPETGRLAVMLNNLGGVSVAEMAILTRELANTPLQARIDWLIGPASLVTALDMKGFSLTTIVLEESIEKALLS
DVETASWQKPVQPRTINVVPSTLDSARVDFTPSANPQVGDYVAQVTGALIDLEEHLNALDAKVGDGDTGSTFAAGAREIA
ERLERQQLPLNDLPTLFALIGERLTVVMGGSSGVLMSIFFTAAGQKLGQGASVAEALNAGLEQMKFYGGADEGDRTMIDA
LQPALAALLAEPENLQAAFAAAQAGADRTCQSSKAGAGRASYLNSDSLLGNMDPGAHAVAMVFKALAER
>Mature_548_residues
SQFFFNQRASLVNDVIEGTIIASPWNNLARLESDPAIRVVVRRDLNKNNVAVISGGGAGHEPAHVGFIGKGMLTAAVCGD
LFASPSVDAVLTAIQAVTGEAGCLLIVKNYTGDRLNFGLAAEKARRLGYNVEMLIVGDDISLPDNKQPRGIAGTILVHKV
AGYFAERGFNLATVLREAQYAASHTASIGVALASCHLPQEADSAPRHQAGHAELGMGIHGEPGASTIATQNSAEIVNLMV
EKLTAALPETGRLAVMLNNLGGVSVAEMAILTRELANTPLQARIDWLIGPASLVTALDMKGFSLTTIVLEESIEKALLSD
VETASWQKPVQPRTINVVPSTLDSARVDFTPSANPQVGDYVAQVTGALIDLEEHLNALDAKVGDGDTGSTFAAGAREIAE
RLERQQLPLNDLPTLFALIGERLTVVMGGSSGVLMSIFFTAAGQKLGQGASVAEALNAGLEQMKFYGGADEGDRTMIDAL
QPALAALLAEPENLQAAFAAAQAGADRTCQSSKAGAGRASYLNSDSLLGNMDPGAHAVAMVFKALAER

Specific function: Catalyzes the phosphorylation of dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=571, Percent_Identity=39.4045534150613, Blast_Score=310, Evalue=2e-84,
Organism=Escherichia coli, GI87081857, Length=339, Percent_Identity=32.1533923303835, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17565018, Length=585, Percent_Identity=34.5299145299145, Blast_Score=253, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6323570, Length=593, Percent_Identity=33.5581787521079, Blast_Score=247, Evalue=4e-66,
Organism=Saccharomyces cerevisiae, GI6321055, Length=597, Percent_Identity=30.9882747068677, Blast_Score=209, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR004007
- InterPro:   IPR012734 [H]

Pfam domain/function: PF02733 Dak1; PF02734 Dak2 [H]

EC number: =2.7.1.29 [H]

Molecular weight: Translated: 57411; Mature: 57280

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFFFNQRASLVNDVIEGTIIASPWNNLARLESDPAIRVVVRRDLNKNNVAVISGGGAG
CCCCHHHHHHHHHHHHHCCCEEECCCHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCCC
HEPAHVGFIGKGMLTAAVCGDLFASPSVDAVLTAIQAVTGEAGCLLIVKNYTGDRLNFGL
CCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCH
AAEKARRLGYNVEMLIVGDDISLPDNKQPRGIAGTILVHKVAGYFAERGFNLATVLREAQ
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
YAASHTASIGVALASCHLPQEADSAPRHQAGHAELGMGIHGEPGASTIATQNSAEIVNLM
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCEECCCHHHHHHHH
VEKLTAALPETGRLAVMLNNLGGVSVAEMAILTRELANTPLQARIDWLIGPASLVTALDM
HHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHEECHHHHHHHHCC
KGFSLTTIVLEESIEKALLSDVETASWQKPVQPRTINVVPSTLDSARVDFTPSANPQVGD
CCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEECCCCCCCHHHH
YVAQVTGALIDLEEHLNALDAKVGDGDTGSTFAAGAREIAERLERQQLPLNDLPTLFALI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GERLTVVMGGSSGVLMSIFFTAAGQKLGQGASVAEALNAGLEQMKFYGGADEGDRTMIDA
CCCEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
LQPALAALLAEPENLQAAFAAAQAGADRTCQSSKAGAGRASYLNSDSLLGNMDPGAHAVA
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHH
MVFKALAER
HHHHHHHCC
>Mature Secondary Structure 
SQFFFNQRASLVNDVIEGTIIASPWNNLARLESDPAIRVVVRRDLNKNNVAVISGGGAG
CCCHHHHHHHHHHHHHCCCEEECCCHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCCC
HEPAHVGFIGKGMLTAAVCGDLFASPSVDAVLTAIQAVTGEAGCLLIVKNYTGDRLNFGL
CCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCH
AAEKARRLGYNVEMLIVGDDISLPDNKQPRGIAGTILVHKVAGYFAERGFNLATVLREAQ
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
YAASHTASIGVALASCHLPQEADSAPRHQAGHAELGMGIHGEPGASTIATQNSAEIVNLM
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCEECCCHHHHHHHH
VEKLTAALPETGRLAVMLNNLGGVSVAEMAILTRELANTPLQARIDWLIGPASLVTALDM
HHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHEECHHHHHHHHCC
KGFSLTTIVLEESIEKALLSDVETASWQKPVQPRTINVVPSTLDSARVDFTPSANPQVGD
CCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEECCCCCCCHHHH
YVAQVTGALIDLEEHLNALDAKVGDGDTGSTFAAGAREIAERLERQQLPLNDLPTLFALI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GERLTVVMGGSSGVLMSIFFTAAGQKLGQGASVAEALNAGLEQMKFYGGADEGDRTMIDA
CCCEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
LQPALAALLAEPENLQAAFAAAQAGADRTCQSSKAGAGRASYLNSDSLLGNMDPGAHAVA
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHH
MVFKALAER
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA