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The map label for this gene is scsC [H]

Identifier: 238896445

GI number: 238896445

Start: 4423945

End: 4424556

Strand: Direct

Name: scsC [H]

Synonym: KP1_4622

Alternate gene names: 238896445

Gene position: 4423945-4424556 (Clockwise)

Preceding gene: 238896444

Following gene: 238896446

Centisome position: 84.29

GC content: 54.9

Gene sequence:

>612_bases
ATGAGAGCTATCACCGCCTTATTACTGCTGTGCGTATCGGCCTTCAGCTTCGCCGCCCCGGCGGAAGAACCACAATCGAA
CGGTAATGACCAGTTAGCCCAGCTGCTGTTTAACGATCCGAATAGCCCGCGCACCGGCGCGAAAGAGCCAAAACTCACAA
TCGTCTCGTTTACCGATTACAACTGTCCTTACTGCAAACAGTTTGATCCGCTGCTGGAAAAAATCGTCCACGATAACCCG
GACATCCAGCTCATCGTTAAGCTGCTGCCGTTTAAAGGGCAGAGTTCGGTGAATGCCGCTAAAGCCGCGCTCTCCACCTG
GCGTCAGCAGCCCGATAAATTCTGGGCGCTGCATCAGCGGCTGATGGCGAAAAAAGGCTATCACGATGACGCCAGTATCG
CCGCCGCGCAGAAGAAAACCGCTACCGATAGCGTAAATATCGATGACAAGACCATGGATTCGCTGAAGATGAACCTGATT
TTGTCGCAGGTGCTGAATATTCAGGGCACCCCGGCAACGATCATCGGCGATCAGATGGTGGCCGGCGCGATCCCTGCTGA
TGAGCTGGAGGGGCTGGTGAAAGAGCAGCTGGCGAAAGCCCGTGGCCAGTAA

Upstream 100 bases:

>100_bases
CAGATTTACGGACCGGAATTGCCACAGGGACAGATTCTGCCTGTGCTGTTAGACCGCGAACACCTTCTCGCCACCCTGTC
CGCCGCTAAAGGAAAATAAC

Downstream 100 bases:

>100_bases
AATCAGGCGCTGGCTGCGCGAGCTGGCGGTGTGGCTGCTGATTGGCGCGGCGGTGAGCCTGGCGGTGGATTATTTTCGCC
AGCCCGCGCTGCCGCAAAAC

Product: copper-sensitivity suppressor protein C

Products: NA

Alternate protein names: Disulfide oxidoreductase D; Thiol-disulfide oxidoreductase D [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MRAITALLLLCVSAFSFAAPAEEPQSNGNDQLAQLLFNDPNSPRTGAKEPKLTIVSFTDYNCPYCKQFDPLLEKIVHDNP
DIQLIVKLLPFKGQSSVNAAKAALSTWRQQPDKFWALHQRLMAKKGYHDDASIAAAQKKTATDSVNIDDKTMDSLKMNLI
LSQVLNIQGTPATIIGDQMVAGAIPADELEGLVKEQLAKARGQ

Sequences:

>Translated_203_residues
MRAITALLLLCVSAFSFAAPAEEPQSNGNDQLAQLLFNDPNSPRTGAKEPKLTIVSFTDYNCPYCKQFDPLLEKIVHDNP
DIQLIVKLLPFKGQSSVNAAKAALSTWRQQPDKFWALHQRLMAKKGYHDDASIAAAQKKTATDSVNIDDKTMDSLKMNLI
LSQVLNIQGTPATIIGDQMVAGAIPADELEGLVKEQLAKARGQ
>Mature_203_residues
MRAITALLLLCVSAFSFAAPAEEPQSNGNDQLAQLLFNDPNSPRTGAKEPKLTIVSFTDYNCPYCKQFDPLLEKIVHDNP
DIQLIVKLLPFKGQSSVNAAKAALSTWRQQPDKFWALHQRLMAKKGYHDDASIAAAQKKTATDSVNIDDKTMDSLKMNLI
LSQVLNIQGTPATIIGDQMVAGAIPADELEGLVKEQLAKARGQ

Specific function: Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. May be required for the stability of secreted proteins with disulfide bonds. Not required for sporulation [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 22177; Mature: 22177

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAITALLLLCVSAFSFAAPAEEPQSNGNDQLAQLLFNDPNSPRTGAKEPKLTIVSFTDY
CHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCC
NCPYCKQFDPLLEKIVHDNPDIQLIVKLLPFKGQSSVNAAKAALSTWRQQPDKFWALHQR
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHH
LMAKKGYHDDASIAAAQKKTATDSVNIDDKTMDSLKMNLILSQVLNIQGTPATIIGDQMV
HHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHH
AGAIPADELEGLVKEQLAKARGQ
HCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRAITALLLLCVSAFSFAAPAEEPQSNGNDQLAQLLFNDPNSPRTGAKEPKLTIVSFTDY
CHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCC
NCPYCKQFDPLLEKIVHDNPDIQLIVKLLPFKGQSSVNAAKAALSTWRQQPDKFWALHQR
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHH
LMAKKGYHDDASIAAAQKKTATDSVNIDDKTMDSLKMNLILSQVLNIQGTPATIIGDQMV
HHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHH
AGAIPADELEGLVKEQLAKARGQ
HCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11844773; 11744713 [H]