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The map label for this gene is scsB [H]

Identifier: 238896444

GI number: 238896444

Start: 4421934

End: 4423943

Strand: Direct

Name: scsB [H]

Synonym: KP1_4621

Alternate gene names: 238896444

Gene position: 4421934-4423943 (Clockwise)

Preceding gene: 238896443

Following gene: 238896445

Centisome position: 84.25

GC content: 64.88

Gene sequence:

>2010_bases
ATGTATATGGTATTCAGGCGACTACTGGTCTGCCTGCTTTGGCTATGGCTGCCCGTCAGCCAGGCCGCCGATAGCGGCTG
GCTGCGCGCCGCCGACAATCAACACGCCAGCGTCCGCCTGCGGGCGCAAACCGAGAGCAATGGCGACACTCGCCTGCTTT
TAGACGTAGCGCTGGAAAAGGGCTGGAAAACCTACTGGCGTTCGCCAGGGGAAGGCGGCATCGCGCCGGCTATCGCCTGG
CATACGCCGCTGGAGGTGAACTGGCGCTGGCCGACGCCGCAGCGCTTCGACGTCGCGGGCATTTCCACTCAGGGCTATCA
CGGCGACGTCAGCTTTCCGATGACGCTGCGCGGGAAGATACCGCCGACGCTTAGCGGCGTCCTGACGCTCTCTACCTGCA
GCAATGTCTGCATTCTCACTGACTATCCCTTTTCGCTGGATATGACGACTCCGGCGGGGGAGCGATTTAATTATGATTTT
ACCCGCGCGATGGGCACACTGCCGCTGCGCGATGGCCTGACTTCGCAGCTGACCGCCAGCTACATCAGCGGCAAACTGAC
GGTGACCGCCCGCCGCGATGCCGGCTGGCAGCAGCCAGCGCTGTTTATCGACAGCATGGAGGATGTCGATTTCGGTAAGC
CGAGCTTTACCAGCCGCGGCGATACGCTGACCGCCACCATACCGGTCACCGATAGCTGGGGCGAAGCGGCGCCGGATCTG
CGCGGTAAAACCTTGTCGCTGGTGCTGGCGGATAGCGGCCAGGCGCAGGAAAGCCAAATCGCCGTCGCCGCCGGCAGCGC
CGCGCCGGGGCTGGCGTTAGGCTGGGTGCTGCTGATGGCGCTGGTCGGCGGGCTTATTCTCAACGTCATGCCCTGCGTGC
TGCCGGTGCTGGCGATGAAGCTCGGCTCGCTGGTGCAAACCGAAGGTCGCGAACGCGGCGCGGTGCGGCGGCAGTTCCTC
GCCTCGGTATTTGGGATCGTCGTCTCGTTCCTGGCGCTGGCGCTGATGATGACCGCGCTACGCCTGGGGAATCAGGCGCT
CGGCTGGGGCATCCAGTTCCAGAACCCGTGGTTTATCGGCGCGATGGCGCTGGTGATGGTGCTGTTCAGCGCCAGTTTAT
TGGGGCTGTTCGAAATCCGCCTCTCCTCCAGCGCCAGCACCTTCCTCGCCACCCGCGGCGGCAACGGCTTAATGGGCCAT
TTCTGGCAGGGCGCCTTCGCCACCCTGCTGGCGACGCCCTGCACCGCGCCGTTCCTCGGCACCGCCGTGTCGGTGGCGCT
GGTGGCGCCCCTGCCGCTGCTGTGGGGCATTTTCTTCGCCATGGGGATCGGCATGAGCCTGCCGTGGCTGCTGATCGTTG
CCTGGCCGGGTCTGGCGCAACGACTGCCACGCCCGGGCCGCTGGATGAATCATCTGCGGGTGGTGCTGGGGCTAATGATG
CTTGGTTCAGCGCTATGGCTGGTCAGCCTGCTGACGATCCACATCGGCCGTACGCCGGTGCTTACCCTGCTGGTGATTCT
GGCCATCGCCCTGCTAGTGGCCACCGCCTGGCGCTACCGCTGGCGGACGGCGCTGCGCGCGGGCGCCTTGGCCATCGTGG
TGGCGGGCGCCGTCGCCTTTGTCGCCCAACAGGACGGCCAGGGCCCGCGCCGGGACCGGGTTAACTGGCAGCCGCTCAGC
GAGCAGGCTATCGCCAGCGCCCTGGCGGAGCATAAGCGGGTATTTATTGATGTCACCGCCGACTGGTGCGTGACCTGTAA
AGCCAACAAATACAACGTGCTGCTGCGCGACGACGTCCAGCAGGCGCTGTTAGCGCCAGACGTAGTCGCCCTGCGCGGCG
ACTGGAGCCGCCCCTCCGCTGACATTAGCCAGTTTTTAACCGCACGCGGCAGCGCCGCGGTGCCGTTTAACCAGATTTAC
GGACCGGAATTGCCACAGGGACAGATTCTGCCTGTGCTGTTAGACCGCGAACACCTTCTCGCCACCCTGTCCGCCGCTAA
AGGAAAATAA

Upstream 100 bases:

>100_bases
TCCCCACCCCGATTGCGGGTGCATCTGCGATTATGCATCTTCCGTGAGTGATTGATTCTCCTGACAGTTCAGGTTAATTC
ATCACTTACGGAGCAAACTT

Downstream 100 bases:

>100_bases
CATGAGAGCTATCACCGCCTTATTACTGCTGTGCGTATCGGCCTTCAGCTTCGCCGCCCCGGCGGAAGAACCACAATCGA
ACGGTAATGACCAGTTAGCC

Product: copper-sensitivity suppressor protein B

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 669; Mature: 669

Protein sequence:

>669_residues
MYMVFRRLLVCLLWLWLPVSQAADSGWLRAADNQHASVRLRAQTESNGDTRLLLDVALEKGWKTYWRSPGEGGIAPAIAW
HTPLEVNWRWPTPQRFDVAGISTQGYHGDVSFPMTLRGKIPPTLSGVLTLSTCSNVCILTDYPFSLDMTTPAGERFNYDF
TRAMGTLPLRDGLTSQLTASYISGKLTVTARRDAGWQQPALFIDSMEDVDFGKPSFTSRGDTLTATIPVTDSWGEAAPDL
RGKTLSLVLADSGQAQESQIAVAAGSAAPGLALGWVLLMALVGGLILNVMPCVLPVLAMKLGSLVQTEGRERGAVRRQFL
ASVFGIVVSFLALALMMTALRLGNQALGWGIQFQNPWFIGAMALVMVLFSASLLGLFEIRLSSSASTFLATRGGNGLMGH
FWQGAFATLLATPCTAPFLGTAVSVALVAPLPLLWGIFFAMGIGMSLPWLLIVAWPGLAQRLPRPGRWMNHLRVVLGLMM
LGSALWLVSLLTIHIGRTPVLTLLVILAIALLVATAWRYRWRTALRAGALAIVVAGAVAFVAQQDGQGPRRDRVNWQPLS
EQAIASALAEHKRVFIDVTADWCVTCKANKYNVLLRDDVQQALLAPDVVALRGDWSRPSADISQFLTARGSAAVPFNQIY
GPELPQGQILPVLLDREHLLATLSAAKGK

Sequences:

>Translated_669_residues
MYMVFRRLLVCLLWLWLPVSQAADSGWLRAADNQHASVRLRAQTESNGDTRLLLDVALEKGWKTYWRSPGEGGIAPAIAW
HTPLEVNWRWPTPQRFDVAGISTQGYHGDVSFPMTLRGKIPPTLSGVLTLSTCSNVCILTDYPFSLDMTTPAGERFNYDF
TRAMGTLPLRDGLTSQLTASYISGKLTVTARRDAGWQQPALFIDSMEDVDFGKPSFTSRGDTLTATIPVTDSWGEAAPDL
RGKTLSLVLADSGQAQESQIAVAAGSAAPGLALGWVLLMALVGGLILNVMPCVLPVLAMKLGSLVQTEGRERGAVRRQFL
ASVFGIVVSFLALALMMTALRLGNQALGWGIQFQNPWFIGAMALVMVLFSASLLGLFEIRLSSSASTFLATRGGNGLMGH
FWQGAFATLLATPCTAPFLGTAVSVALVAPLPLLWGIFFAMGIGMSLPWLLIVAWPGLAQRLPRPGRWMNHLRVVLGLMM
LGSALWLVSLLTIHIGRTPVLTLLVILAIALLVATAWRYRWRTALRAGALAIVVAGAVAFVAQQDGQGPRRDRVNWQPLS
EQAIASALAEHKRVFIDVTADWCVTCKANKYNVLLRDDVQQALLAPDVVALRGDWSRPSADISQFLTARGSAAVPFNQIY
GPELPQGQILPVLLDREHLLATLSAAKGK
>Mature_669_residues
MYMVFRRLLVCLLWLWLPVSQAADSGWLRAADNQHASVRLRAQTESNGDTRLLLDVALEKGWKTYWRSPGEGGIAPAIAW
HTPLEVNWRWPTPQRFDVAGISTQGYHGDVSFPMTLRGKIPPTLSGVLTLSTCSNVCILTDYPFSLDMTTPAGERFNYDF
TRAMGTLPLRDGLTSQLTASYISGKLTVTARRDAGWQQPALFIDSMEDVDFGKPSFTSRGDTLTATIPVTDSWGEAAPDL
RGKTLSLVLADSGQAQESQIAVAAGSAAPGLALGWVLLMALVGGLILNVMPCVLPVLAMKLGSLVQTEGRERGAVRRQFL
ASVFGIVVSFLALALMMTALRLGNQALGWGIQFQNPWFIGAMALVMVLFSASLLGLFEIRLSSSASTFLATRGGNGLMGH
FWQGAFATLLATPCTAPFLGTAVSVALVAPLPLLWGIFFAMGIGMSLPWLLIVAWPGLAQRLPRPGRWMNHLRVVLGLMM
LGSALWLVSLLTIHIGRTPVLTLLVILAIALLVATAWRYRWRTALRAGALAIVVAGAVAFVAQQDGQGPRRDRVNWQPLS
EQAIASALAEHKRVFIDVTADWCVTCKANKYNVLLRDDVQQALLAPDVVALRGDWSRPSADISQFLTARGSAAVPFNQIY
GPELPQGQILPVLLDREHLLATLSAAKGK

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=560, Percent_Identity=26.25, Blast_Score=102, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 72472; Mature: 72472

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYMVFRRLLVCLLWLWLPVSQAADSGWLRAADNQHASVRLRAQTESNGDTRLLLDVALEK
CHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEECCCCCCEEEEEHHHHHH
GWKTYWRSPGEGGIAPAIAWHTPLEVNWRWPTPQRFDVAGISTQGYHGDVSFPMTLRGKI
HHHHHCCCCCCCCCCCEEEECCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCEEECCCC
PPTLSGVLTLSTCSNVCILTDYPFSLDMTTPAGERFNYDFTRAMGTLPLRDGLTSQLTAS
CCCHHHHEEEECCCCEEEEECCCCEEECCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHH
YISGKLTVTARRDAGWQQPALFIDSMEDVDFGKPSFTSRGDTLTATIPVTDSWGEAAPDL
HHCCEEEEEEECCCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCC
RGKTLSLVLADSGQAQESQIAVAAGSAAPGLALGWVLLMALVGGLILNVMPCVLPVLAMK
CCCEEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGSLVQTEGRERGAVRRQFLASVFGIVVSFLALALMMTALRLGNQALGWGIQFQNPWFIG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEECCCHHHH
AMALVMVLFSASLLGLFEIRLSSSASTFLATRGGNGLMGHFWQGAFATLLATPCTAPFLG
HHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHH
TAVSVALVAPLPLLWGIFFAMGIGMSLPWLLIVAWPGLAQRLPRPGRWMNHLRVVLGLMM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEECCCHHHHCCCCCHHHHHHHHHHHHHH
LGSALWLVSLLTIHIGRTPVLTLLVILAIALLVATAWRYRWRTALRAGALAIVVAGAVAF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAQQDGQGPRRDRVNWQPLSEQAIASALAEHKRVFIDVTADWCVTCKANKYNVLLRDDVQ
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCEEEEEECCCEEEEEHHHHH
QALLAPDVVALRGDWSRPSADISQFLTARGSAAVPFNQIYGPELPQGQILPVLLDREHLL
HHHHCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCEEEEEECHHHHH
ATLSAAKGK
HHHHHCCCC
>Mature Secondary Structure
MYMVFRRLLVCLLWLWLPVSQAADSGWLRAADNQHASVRLRAQTESNGDTRLLLDVALEK
CHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEECCCCCCEEEEEHHHHHH
GWKTYWRSPGEGGIAPAIAWHTPLEVNWRWPTPQRFDVAGISTQGYHGDVSFPMTLRGKI
HHHHHCCCCCCCCCCCEEEECCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCEEECCCC
PPTLSGVLTLSTCSNVCILTDYPFSLDMTTPAGERFNYDFTRAMGTLPLRDGLTSQLTAS
CCCHHHHEEEECCCCEEEEECCCCEEECCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHH
YISGKLTVTARRDAGWQQPALFIDSMEDVDFGKPSFTSRGDTLTATIPVTDSWGEAAPDL
HHCCEEEEEEECCCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCC
RGKTLSLVLADSGQAQESQIAVAAGSAAPGLALGWVLLMALVGGLILNVMPCVLPVLAMK
CCCEEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGSLVQTEGRERGAVRRQFLASVFGIVVSFLALALMMTALRLGNQALGWGIQFQNPWFIG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEECCCHHHH
AMALVMVLFSASLLGLFEIRLSSSASTFLATRGGNGLMGHFWQGAFATLLATPCTAPFLG
HHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHH
TAVSVALVAPLPLLWGIFFAMGIGMSLPWLLIVAWPGLAQRLPRPGRWMNHLRVVLGLMM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEECCCHHHHCCCCCHHHHHHHHHHHHHH
LGSALWLVSLLTIHIGRTPVLTLLVILAIALLVATAWRYRWRTALRAGALAIVVAGAVAF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAQQDGQGPRRDRVNWQPLSEQAIASALAEHKRVFIDVTADWCVTCKANKYNVLLRDDVQ
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCEEEEEECCCEEEEEHHHHH
QALLAPDVVALRGDWSRPSADISQFLTARGSAAVPFNQIYGPELPQGQILPVLLDREHLL
HHHHCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCEEEEEECHHHHH
ATLSAAKGK
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA