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The map label for this gene is dsbC [H]

Identifier: 238896433

GI number: 238896433

Start: 4413690

End: 4414403

Strand: Reverse

Name: dsbC [H]

Synonym: KP1_4609

Alternate gene names: 238896433

Gene position: 4414403-4413690 (Counterclockwise)

Preceding gene: 238896434

Following gene: 238896432

Centisome position: 84.11

GC content: 58.12

Gene sequence:

>714_bases
ATGAAAAAAGGTTTATTGATGTTCACCCTGCTGGCGGCCTCCCTTTCAGGAGCGGCGCACGCCGATAGCGCGGCAATTAA
ACAGTCGCTGGCGAAGCTGGGTGTGCAGAGCACCGATATTCAACCATCGCCGGTTTCCGGGATGAGCACGGTGCTGACCG
ACAGCGGCGTGCTGTACGTGACCGACGACGGCAAACATATCATCCAGGGGCCGATGTACGACGTGAGCGGCGCGCAGCCG
GTCAACGTCACCAACCAGCTGCTGCTGGGTAAGCTGAACGCGCTGAGCAATGAGATGATTGTCTACAAAGCGCCGAAGGA
GCAGCACGTCATCACCGTCTTCACCGATATTACCTGCGGCTACTGTCATAAACTGCACGAGCAGATGAGCGACTACAACG
CGCTGGGGATCACCGTGCGCTATCTGGCTTTCCCGCGCCAGGGTCTGCAAAGCCAGGCGGAGCAGGACATGAAGGCCATC
TGGTGCGCGAAAGATCGCAACAAAGCGCTGGATGACGCCATGAATGGTAAAGGCGTGCAGCCGGCGAGCTGCAGCGTAGA
TATCGCCAAACATTACACCCTCGGCGTGCAGATGGGCGTCAACGGTACGCCGGCGATGGTCCTCAGTAACGGCATGGTGC
TGCCGGGCTATCAGGGGCCGAAAGAGCTGAAGGCGTTCCTTGATGAGCACAAAAAACAGACAAGCGGTAACTGA

Upstream 100 bases:

>100_bases
TCCACCACGCAGATATACACCCACGTGGCGACCGAGCGTCTGCGACAACTTCATCAACAGCACCACCCGCGGGCGTGAGT
GCTGAACAAAAGGACTGAGT

Downstream 100 bases:

>100_bases
TTCGCGTGAAACAACAGATACAACTACGCCGCCGCGAGGCGGTTGACGGCGTCGAACTCCCCGCCGACCTGCCGCCGCTG
CTGCAGCGGCTATATGCCAG

Product: thiol:disulfide interchange protein DsbC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MKKGLLMFTLLAASLSGAAHADSAAIKQSLAKLGVQSTDIQPSPVSGMSTVLTDSGVLYVTDDGKHIIQGPMYDVSGAQP
VNVTNQLLLGKLNALSNEMIVYKAPKEQHVITVFTDITCGYCHKLHEQMSDYNALGITVRYLAFPRQGLQSQAEQDMKAI
WCAKDRNKALDDAMNGKGVQPASCSVDIAKHYTLGVQMGVNGTPAMVLSNGMVLPGYQGPKELKAFLDEHKKQTSGN

Sequences:

>Translated_237_residues
MKKGLLMFTLLAASLSGAAHADSAAIKQSLAKLGVQSTDIQPSPVSGMSTVLTDSGVLYVTDDGKHIIQGPMYDVSGAQP
VNVTNQLLLGKLNALSNEMIVYKAPKEQHVITVFTDITCGYCHKLHEQMSDYNALGITVRYLAFPRQGLQSQAEQDMKAI
WCAKDRNKALDDAMNGKGVQPASCSVDIAKHYTLGVQMGVNGTPAMVLSNGMVLPGYQGPKELKAFLDEHKKQTSGN
>Mature_237_residues
MKKGLLMFTLLAASLSGAAHADSAAIKQSLAKLGVQSTDIQPSPVSGMSTVLTDSGVLYVTDDGKHIIQGPMYDVSGAQP
VNVTNQLLLGKLNALSNEMIVYKAPKEQHVITVFTDITCGYCHKLHEQMSDYNALGITVRYLAFPRQGLQSQAEQDMKAI
WCAKDRNKALDDAMNGKGVQPASCSVDIAKHYTLGVQMGVNGTPAMVLSNGMVLPGYQGPKELKAFLDEHKKQTSGN

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=236, Percent_Identity=77.1186440677966, Blast_Score=393, Evalue=1e-111,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 25427; Mature: 25427

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGLLMFTLLAASLSGAAHADSAAIKQSLAKLGVQSTDIQPSPVSGMSTVLTDSGVLYV
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHEECCCEEEE
TDDGKHIIQGPMYDVSGAQPVNVTNQLLLGKLNALSNEMIVYKAPKEQHVITVFTDITCG
ECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCHH
YCHKLHEQMSDYNALGITVRYLAFPRQGLQSQAEQDMKAIWCAKDRNKALDDAMNGKGVQ
HHHHHHHHHHCCCHHHEEEEEECCCHHHHHHHHHHHHHHEECCCCCCHHHHHHCCCCCCC
PASCSVDIAKHYTLGVQMGVNGTPAMVLSNGMVLPGYQGPKELKAFLDEHKKQTSGN
CCCCEEEEHHEEEEEEEECCCCCCCEEEECCEEECCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKGLLMFTLLAASLSGAAHADSAAIKQSLAKLGVQSTDIQPSPVSGMSTVLTDSGVLYV
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHEECCCEEEE
TDDGKHIIQGPMYDVSGAQPVNVTNQLLLGKLNALSNEMIVYKAPKEQHVITVFTDITCG
ECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCHH
YCHKLHEQMSDYNALGITVRYLAFPRQGLQSQAEQDMKAIWCAKDRNKALDDAMNGKGVQ
HHHHHHHHHHCCCHHHEEEEEECCCHHHHHHHHHHHHHHEECCCCCCHHHHHHCCCCCCC
PASCSVDIAKHYTLGVQMGVNGTPAMVLSNGMVLPGYQGPKELKAFLDEHKKQTSGN
CCCCEEEEHHEEEEEEEECCCCCCCEEEECCEEECCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609; 9370270 [H]