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The map label for this gene is linR [H]

Identifier: 238896426

GI number: 238896426

Start: 4404652

End: 4405581

Strand: Reverse

Name: linR [H]

Synonym: KP1_4601

Alternate gene names: 238896426

Gene position: 4405581-4404652 (Counterclockwise)

Preceding gene: 238896428

Following gene: 238896421

Centisome position: 83.94

GC content: 56.56

Gene sequence:

>930_bases
ATGTCTGATCCCGATTTTAATTTGCTGGTAGCTCTCGACGTATTGCTGAGTGAAGCGAGTGTCGCAGGTGCGGCTCGTCG
TCTGAACCTCAGCACTTCGGCCATGAGCCGGACATTAAGCAGGTTACGCGATGTCACAGGAGACCCGATCCTGGTACGCG
CCGGGCGTAACATGGTACTGACCCCGTGGGCCGAAGCGACCCGGGATCGCGCCAGGCGTGCAGTGCACGATGCCAGGGCG
GTATTACAGCCCTCAACTGAAACGTTCAGCGCGCAAAATCTGGCGCGTCTTTTTACCATCAGGGCAAACGATGGTTTTGT
GGTGGCGTTTGGGCCTGCGCTTATAGCAGCGGTTGCCGACGCCGCGCCGGACGTCTGTATACGCTTCGCGCCTAAGCCGG
AAAAAACGTCGCGCTATCTTCGGGAAGGACTGGTTGATCTGGAGATTGGCGTTCAGAGTAATATGGGGCCAGAAATACGG
CTGCAACGACTGTTTGAGGATCGGTTTGTTGGCGTCGTCCGTAAAGGGCACCCGCTGGCTAAGCAGGCTGAAATAGGCGT
GAGTGATTATGTCGCCTGGGGCCATGTGGTAGCGTCACCCGAGGGCGCGTTGCACGGATCCGTTGACGATGCGCTGGCCG
AACTGGGGACAAAACGTAAAATTGCAAGCGTCGTACCGGGATTTCCGACAGCACTTTCCGTGGCGCTGGAATCGGATCTT
ATCGCCATGATACCCGCACTCTATTTACTCAATCAGCAGGTAACGGACCAGGTACACCTTTTCGAGCTGCCGTTCAAAAG
CCGTCGTATTACGGTATCGCAGATGTGGCACCCAAGAATGGAACGCGACCCCGGTCACCGCTGGCTGAGAGAGCAAATTC
TTGCGATATGCGGTGTGGCCCGGTCAGTCATGACTAAGGAGCCTGTATAG

Upstream 100 bases:

>100_bases
GACAAAACTATAAAGATGGCTTTTACCAGGCGGAAGGCGCACTATTTTCACTTTATTGTTGCATCAAACGCCTTATCTTA
ATGTGCTGGGAGGAAGGGTA

Downstream 100 bases:

>100_bases
CGATTGCTATAACATCAATTTATATTAAATGAATAATTCAATTCATTGATATGTAATATAAAATACATCAATCGAAGTAG
CGGTGTAGTAGCTAAATTGA

Product: putative LysR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSDPDFNLLVALDVLLSEASVAGAARRLNLSTSAMSRTLSRLRDVTGDPILVRAGRNMVLTPWAEATRDRARRAVHDARA
VLQPSTETFSAQNLARLFTIRANDGFVVAFGPALIAAVADAAPDVCIRFAPKPEKTSRYLREGLVDLEIGVQSNMGPEIR
LQRLFEDRFVGVVRKGHPLAKQAEIGVSDYVAWGHVVASPEGALHGSVDDALAELGTKRKIASVVPGFPTALSVALESDL
IAMIPALYLLNQQVTDQVHLFELPFKSRRITVSQMWHPRMERDPGHRWLREQILAICGVARSVMTKEPV

Sequences:

>Translated_309_residues
MSDPDFNLLVALDVLLSEASVAGAARRLNLSTSAMSRTLSRLRDVTGDPILVRAGRNMVLTPWAEATRDRARRAVHDARA
VLQPSTETFSAQNLARLFTIRANDGFVVAFGPALIAAVADAAPDVCIRFAPKPEKTSRYLREGLVDLEIGVQSNMGPEIR
LQRLFEDRFVGVVRKGHPLAKQAEIGVSDYVAWGHVVASPEGALHGSVDDALAELGTKRKIASVVPGFPTALSVALESDL
IAMIPALYLLNQQVTDQVHLFELPFKSRRITVSQMWHPRMERDPGHRWLREQILAICGVARSVMTKEPV
>Mature_308_residues
SDPDFNLLVALDVLLSEASVAGAARRLNLSTSAMSRTLSRLRDVTGDPILVRAGRNMVLTPWAEATRDRARRAVHDARAV
LQPSTETFSAQNLARLFTIRANDGFVVAFGPALIAAVADAAPDVCIRFAPKPEKTSRYLREGLVDLEIGVQSNMGPEIRL
QRLFEDRFVGVVRKGHPLAKQAEIGVSDYVAWGHVVASPEGALHGSVDDALAELGTKRKIASVVPGFPTALSVALESDLI
AMIPALYLLNQQVTDQVHLFELPFKSRRITVSQMWHPRMERDPGHRWLREQILAICGVARSVMTKEPV

Specific function: Positively regulates the transcription of the linD and linE genes that are involved in gamma-hexachlorocyclohexane degradation [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=299, Percent_Identity=25.0836120401338, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1790147, Length=301, Percent_Identity=24.5847176079734, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87081766, Length=285, Percent_Identity=23.859649122807, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33885; Mature: 33753

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPDFNLLVALDVLLSEASVAGAARRLNLSTSAMSRTLSRLRDVTGDPILVRAGRNMVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEECCCCEEE
TPWAEATRDRARRAVHDARAVLQPSTETFSAQNLARLFTIRANDGFVVAFGPALIAAVAD
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEEECCCCEEEEEHHHHHHHHHH
AAPDVCIRFAPKPEKTSRYLREGLVDLEIGVQSNMGPEIRLQRLFEDRFVGVVRKGHPLA
CCCCCEEEECCCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
KQAEIGVSDYVAWGHVVASPEGALHGSVDDALAELGTKRKIASVVPGFPTALSVALESDL
HHHCCCHHHHHHHCEEEECCCCCCCCCHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHH
IAMIPALYLLNQQVTDQVHLFELPFKSRRITVSQMWHPRMERDPGHRWLREQILAICGVA
HHHHHHHHHHHHHHHCCEEEEECCCCCCEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
RSVMTKEPV
HHHHHCCCC
>Mature Secondary Structure 
SDPDFNLLVALDVLLSEASVAGAARRLNLSTSAMSRTLSRLRDVTGDPILVRAGRNMVL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEECCCCEEE
TPWAEATRDRARRAVHDARAVLQPSTETFSAQNLARLFTIRANDGFVVAFGPALIAAVAD
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEEECCCCEEEEEHHHHHHHHHH
AAPDVCIRFAPKPEKTSRYLREGLVDLEIGVQSNMGPEIRLQRLFEDRFVGVVRKGHPLA
CCCCCEEEECCCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
KQAEIGVSDYVAWGHVVASPEGALHGSVDDALAELGTKRKIASVVPGFPTALSVALESDL
HHHCCCHHHHHHHCEEEECCCCCCCCCHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHH
IAMIPALYLLNQQVTDQVHLFELPFKSRRITVSQMWHPRMERDPGHRWLREQILAICGVA
HHHHHHHHHHHHHHHCCEEEEECCCCCCEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
RSVMTKEPV
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11916699 [H]