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The map label for this gene is arsR [H]

Identifier: 238896417

GI number: 238896417

Start: 4398606

End: 4398935

Strand: Reverse

Name: arsR [H]

Synonym: KP1_4592

Alternate gene names: 238896417

Gene position: 4398935-4398606 (Counterclockwise)

Preceding gene: 238896420

Following gene: 238896416

Centisome position: 83.81

GC content: 60.91

Gene sequence:

>330_bases
ATGTCTTTATTGCCCCTGCAACTGTTCAAAAACCTCGCCGATGAAACTCGGCTGGGGATCGTATTGCTGCTCAAGGCGCG
TGGAGAGCTGTGCGTGTGCGATCTCTGTACGGCGCTCGCCCAGTCCCAGCCCAAGATCTCCCGCCATCTGGCGATGCTCC
GTGAGAGCGGATTGCTGCTGGATCGTAAACAGGGTAAGTGGGTCCATTACCGCCTCTCTCCGCAGATGCCGGCCTGGGCG
GCGCAGGTGATTGAGCAGGCCTGGCTCAGTCAGCAGGAGGATGTGCGGCTGATGATCAGCAGACTGGCTGGCGGGCCGGG
TTGCCGGTAA

Upstream 100 bases:

>100_bases
ATGCTCATCGCAGACGTGAATTAATATATATGTTTTTGCGCATGTATATTGATCTTACTTTGTGGCCCCGTATGCTGTCC
GTCACGCTTGAGGAGAAATC

Downstream 100 bases:

>100_bases
AAAATTTATCTTAACATATATGATTTTTCGAATGTGATTGGCGGAGGAACGATGTTGCTGGCAGGTACGATTTTTATCCT
GACCCTGGTGCTGGTGATTT

Product: ArsR family transcriptional repressor for arsenical resistance

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 109; Mature: 108

Protein sequence:

>109_residues
MSLLPLQLFKNLADETRLGIVLLLKARGELCVCDLCTALAQSQPKISRHLAMLRESGLLLDRKQGKWVHYRLSPQMPAWA
AQVIEQAWLSQQEDVRLMISRLAGGPGCR

Sequences:

>Translated_109_residues
MSLLPLQLFKNLADETRLGIVLLLKARGELCVCDLCTALAQSQPKISRHLAMLRESGLLLDRKQGKWVHYRLSPQMPAWA
AQVIEQAWLSQQEDVRLMISRLAGGPGCR
>Mature_108_residues
SLLPLQLFKNLADETRLGIVLLLKARGELCVCDLCTALAQSQPKISRHLAMLRESGLLLDRKQGKWVHYRLSPQMPAWAA
QVIEQAWLSQQEDVRLMISRLAGGPGCR

Specific function: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenat

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=101, Percent_Identity=77.2277227722772, Blast_Score=161, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12251; Mature: 12120

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00846 HTH_ARSR_1 ; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLPLQLFKNLADETRLGIVLLLKARGELCVCDLCTALAQSQPKISRHLAMLRESGLLL
CCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCEE
DRKQGKWVHYRLSPQMPAWAAQVIEQAWLSQQEDVRLMISRLAGGPGCR
ECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SLLPLQLFKNLADETRLGIVLLLKARGELCVCDLCTALAQSQPKISRHLAMLRESGLLL
CCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCEE
DRKQGKWVHYRLSPQMPAWAAQVIEQAWLSQQEDVRLMISRLAGGPGCR
ECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2408017; 1838573; 8416957 [H]