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The map label for this gene is cbiL [H]

Identifier: 238896293

GI number: 238896293

Start: 4274708

End: 4275418

Strand: Reverse

Name: cbiL [H]

Synonym: KP1_4454

Alternate gene names: 238896293

Gene position: 4275418-4274708 (Counterclockwise)

Preceding gene: 238896294

Following gene: 238896292

Centisome position: 81.46

GC content: 65.96

Gene sequence:

>711_bases
ATGAGCGGCAAACTCTACGCCCTGAGCACCGGGCCGGGGGCGGCCGATCTGATCACCGTGCGTGCGGCGCGGATCCTCGG
CCAGCTGGATGTGCTGTATGCGCCAGCCGGCCGCAAAGGCGGCGACAGCCTCGCGCTCTCCATCGTGCGCGAGTACCTTG
GCGCACACACGGAGGTCCGCTGCTGCCATTTTCCGATGAGCGCCGACAGCGCGGAAAAAGAGGCGGTGTGGAACGACGTT
ACCGCGGCGCTGGCCCAGGAGGTGGCGGCGGGCAGGCAGGTCGGATTTATCACCCTCGGCGACGCCATGTTGTTCAGCAC
CTGGGTCTTTCTGCTGCAGCGGATTGGCTGCCCGGACTGGCTGGAGATTGTCCCTGGCGTTACCTCCTTCGCCGCCATTG
CCGCGCGGGCGAAAACCCCGCTGGCTATGGAGCAGCAGTCGCTGGCGGTGATCTCCTGTACCGCGCCGGAAGCGGACATT
GCCGCGGCGCTGCGCCAGCATGACAGTCTGGTGCTGATGAAAGTCTACGGCCGCTTTGCCCGCATTAAGGCGCTGCTGGC
GCAGGCGGGGCTGCTGGATGCGGCGCTGATGATGTCAGAGGCCACCCTGCCGGGCGAGCAGTGCTGGCGCCGTCTGCGCG
AGGTCAGCGATGACCAGCCGCTGCCCTATTTCTCGACCATCCTGGTTAACAAACAATGGGAGGAGGCGTAA

Upstream 100 bases:

>100_bases
CCACGCCGTGGCTGAACGGGTTAGGGGAAAATCCGGCGGTGCGGGCAATGTTTGTTGCCCATCTGCAGCAGGCGCTGAAT
AACGCGATGGAGAAAGCAGC

Downstream 100 bases:

>100_bases
TGAATCAGGTGAAATCGCTGAAGCAGCTTTCGTATGGGGGGCTGGCGGCCGCTGTTCTGCTGATCATCGTCCCGCAGGAG
GCGTTCGCCATGCATATCAT

Product: cobalt-precorrin-2 C(20)-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSGKLYALSTGPGAADLITVRAARILGQLDVLYAPAGRKGGDSLALSIVREYLGAHTEVRCCHFPMSADSAEKEAVWNDV
TAALAQEVAAGRQVGFITLGDAMLFSTWVFLLQRIGCPDWLEIVPGVTSFAAIAARAKTPLAMEQQSLAVISCTAPEADI
AAALRQHDSLVLMKVYGRFARIKALLAQAGLLDAALMMSEATLPGEQCWRRLREVSDDQPLPYFSTILVNKQWEEA

Sequences:

>Translated_236_residues
MSGKLYALSTGPGAADLITVRAARILGQLDVLYAPAGRKGGDSLALSIVREYLGAHTEVRCCHFPMSADSAEKEAVWNDV
TAALAQEVAAGRQVGFITLGDAMLFSTWVFLLQRIGCPDWLEIVPGVTSFAAIAARAKTPLAMEQQSLAVISCTAPEADI
AAALRQHDSLVLMKVYGRFARIKALLAQAGLLDAALMMSEATLPGEQCWRRLREVSDDQPLPYFSTILVNKQWEEA
>Mature_235_residues
SGKLYALSTGPGAADLITVRAARILGQLDVLYAPAGRKGGDSLALSIVREYLGAHTEVRCCHFPMSADSAEKEAVWNDVT
AALAQEVAAGRQVGFITLGDAMLFSTWVFLLQRIGCPDWLEIVPGVTSFAAIAARAKTPLAMEQQSLAVISCTAPEADIA
AALRQHDSLVLMKVYGRFARIKALLAQAGLLDAALMMSEATLPGEQCWRRLREVSDDQPLPYFSTILVNKQWEEA

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 25451; Mature: 25319

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00839 SUMT_1 ; PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGKLYALSTGPGAADLITVRAARILGQLDVLYAPAGRKGGDSLALSIVREYLGAHTEVR
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHCCCCEEE
CCHFPMSADSAEKEAVWNDVTAALAQEVAAGRQVGFITLGDAMLFSTWVFLLQRIGCPDW
EEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHCCCCHH
LEIVPGVTSFAAIAARAKTPLAMEQQSLAVISCTAPEADIAAALRQHDSLVLMKVYGRFA
HHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCEEHHHHHHHHH
RIKALLAQAGLLDAALMMSEATLPGEQCWRRLREVSDDQPLPYFSTILVNKQWEEA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCC
>Mature Secondary Structure 
SGKLYALSTGPGAADLITVRAARILGQLDVLYAPAGRKGGDSLALSIVREYLGAHTEVR
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHCCCCEEE
CCHFPMSADSAEKEAVWNDVTAALAQEVAAGRQVGFITLGDAMLFSTWVFLLQRIGCPDW
EEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHCCCCHH
LEIVPGVTSFAAIAARAKTPLAMEQQSLAVISCTAPEADIAAALRQHDSLVLMKVYGRFA
HHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCEEHHHHHHHHH
RIKALLAQAGLLDAALMMSEATLPGEQCWRRLREVSDDQPLPYFSTILVNKQWEEA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609 [H]