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The map label for this gene is cbiK [H]

Identifier: 238896294

GI number: 238896294

Start: 4275415

End: 4276209

Strand: Reverse

Name: cbiK [H]

Synonym: KP1_4455

Alternate gene names: 238896294

Gene position: 4276209-4275415 (Counterclockwise)

Preceding gene: 238896295

Following gene: 238896293

Centisome position: 81.47

GC content: 60.38

Gene sequence:

>795_bases
ATGAAAAAAGCACTTCTGGTGGTGAGCTTTGGCACCAGCTATCACGACACCCGCGAAAAGAACATCGACGCCTGCGAGCG
CGATCTGGCCGCCAGCTGCCCGGACCGCACGCTGTTCCGCGCCTTCACCTCGGGGATGATTATTCGCAAACTGCAGCAGC
GCGATGGTATTCATATCGATACTCCGCTGCAGGCTCTGCAAAAGCTGGCCGAGCAGGGATACCAGGATGTGGCTGTCCAG
TCCCTGCACATTATCAACGGCGACGAGTACGAGAAGATCGTTCGCGAAGTGCAGAGTATGCGCCCGCGCTTTCAGCGTCT
GACGCTGGGCGCGCCGCTGTTGAGCGGTCATGGCGATTATGTGCAGCTGATGCAGGCCCTGCGCCAGCAGATGCCGCCGC
TGGCGGCGACGGAGCGAGTGGTGTTTATGGGGCACGGCGCCAGCCACCACGCCTTCGCGGCCTACGCCTGTCTGGATCAT
ATGATGGCGGTGCAGGGTTTTCCGGCGCGGGTGGGGGCGGTGGAAAGCTATCCCGAAGTGGACATCGTCATTAACGAACT
CTCCCGCCAGGGCGTGACCGGCGTGCATCTGATGCCGCTGATGCTGGTGGCCGGCGATCATGCCATTAATGATATGGCCT
CCGACGAAGACGATTCGTGGAAAACCCGCTTTAATGCCGCCGGTATTCCTGCCACGCCGTGGCTGAACGGGTTAGGGGAA
AATCCGGCGGTGCGGGCAATGTTTGTTGCCCATCTGCAGCAGGCGCTGAATAACGCGATGGAGAAAGCAGCATGA

Upstream 100 bases:

>100_bases
CGTCCGGCGCCGCTGGTGACGGGCGATGAACTACTGCAAAGCCAGGCCGATTTCACTGCGCGGCTGACGCGCTGGCTGTC
GGCGACTTGAGGAAGAGGAT

Downstream 100 bases:

>100_bases
GCGGCAAACTCTACGCCCTGAGCACCGGGCCGGGGGCGGCCGATCTGATCACCGTGCGTGCGGCGCGGATCCTCGGCCAG
CTGGATGTGCTGTATGCGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MKKALLVVSFGTSYHDTREKNIDACERDLAASCPDRTLFRAFTSGMIIRKLQQRDGIHIDTPLQALQKLAEQGYQDVAVQ
SLHIINGDEYEKIVREVQSMRPRFQRLTLGAPLLSGHGDYVQLMQALRQQMPPLAATERVVFMGHGASHHAFAAYACLDH
MMAVQGFPARVGAVESYPEVDIVINELSRQGVTGVHLMPLMLVAGDHAINDMASDEDDSWKTRFNAAGIPATPWLNGLGE
NPAVRAMFVAHLQQALNNAMEKAA

Sequences:

>Translated_264_residues
MKKALLVVSFGTSYHDTREKNIDACERDLAASCPDRTLFRAFTSGMIIRKLQQRDGIHIDTPLQALQKLAEQGYQDVAVQ
SLHIINGDEYEKIVREVQSMRPRFQRLTLGAPLLSGHGDYVQLMQALRQQMPPLAATERVVFMGHGASHHAFAAYACLDH
MMAVQGFPARVGAVESYPEVDIVINELSRQGVTGVHLMPLMLVAGDHAINDMASDEDDSWKTRFNAAGIPATPWLNGLGE
NPAVRAMFVAHLQQALNNAMEKAA
>Mature_264_residues
MKKALLVVSFGTSYHDTREKNIDACERDLAASCPDRTLFRAFTSGMIIRKLQQRDGIHIDTPLQALQKLAEQGYQDVAVQ
SLHIINGDEYEKIVREVQSMRPRFQRLTLGAPLLSGHGDYVQLMQALRQQMPPLAATERVVFMGHGASHHAFAAYACLDH
MMAVQGFPARVGAVESYPEVDIVINELSRQGVTGVHLMPLMLVAGDHAINDMASDEDDSWKTRFNAAGIPATPWLNGLGE
NPAVRAMFVAHLQQALNNAMEKAA

Specific function: Chelates cobalt to the cobalamin precursor as part of the anaerobic pathway to cobalamin biosynthesis [H]

COG id: COG4822

COG function: function code H; Cobalamin biosynthesis protein CbiK, Co2+ chelatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010388 [H]

Pfam domain/function: PF06180 CbiK [H]

EC number: =4.99.1.3 [H]

Molecular weight: Translated: 29132; Mature: 29132

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKALLVVSFGTSYHDTREKNIDACERDLAASCPDRTLFRAFTSGMIIRKLQQRDGIHID
CCCEEEEEEECCCCCHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEC
TPLQALQKLAEQGYQDVAVQSLHIINGDEYEKIVREVQSMRPRFQRLTLGAPLLSGHGDY
CHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHH
VQLMQALRQQMPPLAATERVVFMGHGASHHAFAAYACLDHMMAVQGFPARVGAVESYPEV
HHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCH
DIVINELSRQGVTGVHLMPLMLVAGDHAINDMASDEDDSWKTRFNAAGIPATPWLNGLGE
HHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHCCCCCCCCHHHHCCCC
NPAVRAMFVAHLQQALNNAMEKAA
CHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKALLVVSFGTSYHDTREKNIDACERDLAASCPDRTLFRAFTSGMIIRKLQQRDGIHID
CCCEEEEEEECCCCCHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEC
TPLQALQKLAEQGYQDVAVQSLHIINGDEYEKIVREVQSMRPRFQRLTLGAPLLSGHGDY
CHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHH
VQLMQALRQQMPPLAATERVVFMGHGASHHAFAAYACLDHMMAVQGFPARVGAVESYPEV
HHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCH
DIVINELSRQGVTGVHLMPLMLVAGDHAINDMASDEDDSWKTRFNAAGIPATPWLNGLGE
HHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHCCCCCCCCHHHHCCCC
NPAVRAMFVAHLQQALNNAMEKAA
CHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 9150215; 10451360 [H]