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The map label for this gene is yaaU [H]

Identifier: 238896262

GI number: 238896262

Start: 4241845

End: 4243266

Strand: Reverse

Name: yaaU [H]

Synonym: KP1_4420

Alternate gene names: 238896262

Gene position: 4243266-4241845 (Counterclockwise)

Preceding gene: 238896263

Following gene: 238896261

Centisome position: 80.85

GC content: 58.51

Gene sequence:

>1422_bases
ATGAGTACATTACCAGTGGATAATCCCGGTATCGCTTCGGTACCGGTCAGTAGCGTCGGGGATGTGGCGCGGCTAATTAA
TTCCGGCAAGGAACATGCGAAATATGCGCGGATGATTGTCTTCCTCGCGCTGGGGGGCGTTTTTCTCGACGCATATGACT
TAACCACGCTCTCCTACGGTATTGATGACGTTGTACGTGAATTTCAGCTCTCACCGCTGCTGACCGGCCTGGTGACTTCG
TCCATTATGGTCGGGACTATCGTCGGCAATATTATCGGCGGCTGGTTGACCGATAAATATGGTCGCTATTCGGTTTTTAT
GGCCGATATGTTCTTTTTCGTGATTTCGGCTATCGCCGCCGGGCTGGCGCCGAACGTCTGGGTGTTGATTGGCGCCCGTT
TCCTGATGGGCATCGGCGTTGGCATCGACCTGCCGGTAGCGATGTCCTATCTGGCCGAGTTTTCCCGCTTTGCCGGCAAA
GGCAACAAAGCGGCTCGCCTCGCGGCGTGGTGCCCGATGTGGTACGCCGCCTCAACCGTCTGCTTTCTCATTATCTTCGG
CCTCTATTTCCTGCTGCCGCAGGAGCATCTTGACTGGCTATGGCGCGCCTCTCTGCTGTTCGGCGCCGTGCCGGCACTGC
TGATTATTGCCGTCCGCAGTCGATTTATGAATGAATCCCCGCTGTGGGCGGCGAACCAGGGCGATCTGACCTCTGCAGTG
CGTATTTTACGCGACTCCTGGGGGATCCATGCCCATGAGGTCCCGGCGGCGAAGCCCGCGCCAGCGCCGAAAGTGAGCTT
CCGCGTGCTGTTCGAAAAACCCTACCGCGAGCGGACTATCGTCGCCGGGGTGATGAATATCTGTATCTCCTTCGAGTACA
CGGCGATTGCCTTTTTCCTGCCGTCAATTCTTGCCCAGTTCCTCGGGGCTGGCGTCTTCGAAACTATTTCGGCATCGCTG
GGGCTGAACGCCCTGTTTGCTTTTACCGGTGGGCTGCTCGGTATGCATCTGGCGTGGAAATATCCTTCGCGTCATGTGGC
GATAGCCGGCTTCGCCCTGCAGTTTGTGGCGCTGATTGTGCTGGCGCTGGTGGGGCAACCGCACGCGACGGCAGGTATCG
TGCTGGCTATCGCGATGCTGGGGCTGTGGCTGTTCGCCGAAGGGTTTGGCCCGGGGGCGCAGCTGATGATCTACCCGGCG
CTCTCCTATCCTACTGCCATTCGCGCCACCGGGGTCGGTTTCAGCCGGGCACTCTCCGGGATCGGCAGCGCGCTGGCGTT
GTTTATTCTGCCGCTGCTGCAGGCCTACCTCGGCACGCAGATGTTCTGGGTGGTCTCGCTTGCCGCCATTATTCCCATTT
TCTTCCTGCTGGCGGTCCGTCATGAACCGACGCGAGAAGATATCGACGCACTTCATGAATAA

Upstream 100 bases:

>100_bases
ATTGATTATATTGATTTTTATAGAATTATTTGTTGTTTTGATTCTCGTCGCGCGCGGTCTATAACCGCTGATGACCTGCA
CAAAATAATAAGGTGAAAAA

Downstream 100 bases:

>100_bases
GGAACTGACAATGACCCTGCTCTCCACTGGCACCGATTATGACGCGCTGGCGGCCGCCTTCCGCCCGATATTCACCCGTA
TCGCCCAGGGCGCTGCGGAG

Product: putative general substrate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MSTLPVDNPGIASVPVSSVGDVARLINSGKEHAKYARMIVFLALGGVFLDAYDLTTLSYGIDDVVREFQLSPLLTGLVTS
SIMVGTIVGNIIGGWLTDKYGRYSVFMADMFFFVISAIAAGLAPNVWVLIGARFLMGIGVGIDLPVAMSYLAEFSRFAGK
GNKAARLAAWCPMWYAASTVCFLIIFGLYFLLPQEHLDWLWRASLLFGAVPALLIIAVRSRFMNESPLWAANQGDLTSAV
RILRDSWGIHAHEVPAAKPAPAPKVSFRVLFEKPYRERTIVAGVMNICISFEYTAIAFFLPSILAQFLGAGVFETISASL
GLNALFAFTGGLLGMHLAWKYPSRHVAIAGFALQFVALIVLALVGQPHATAGIVLAIAMLGLWLFAEGFGPGAQLMIYPA
LSYPTAIRATGVGFSRALSGIGSALALFILPLLQAYLGTQMFWVVSLAAIIPIFFLLAVRHEPTREDIDALHE

Sequences:

>Translated_473_residues
MSTLPVDNPGIASVPVSSVGDVARLINSGKEHAKYARMIVFLALGGVFLDAYDLTTLSYGIDDVVREFQLSPLLTGLVTS
SIMVGTIVGNIIGGWLTDKYGRYSVFMADMFFFVISAIAAGLAPNVWVLIGARFLMGIGVGIDLPVAMSYLAEFSRFAGK
GNKAARLAAWCPMWYAASTVCFLIIFGLYFLLPQEHLDWLWRASLLFGAVPALLIIAVRSRFMNESPLWAANQGDLTSAV
RILRDSWGIHAHEVPAAKPAPAPKVSFRVLFEKPYRERTIVAGVMNICISFEYTAIAFFLPSILAQFLGAGVFETISASL
GLNALFAFTGGLLGMHLAWKYPSRHVAIAGFALQFVALIVLALVGQPHATAGIVLAIAMLGLWLFAEGFGPGAQLMIYPA
LSYPTAIRATGVGFSRALSGIGSALALFILPLLQAYLGTQMFWVVSLAAIIPIFFLLAVRHEPTREDIDALHE
>Mature_472_residues
STLPVDNPGIASVPVSSVGDVARLINSGKEHAKYARMIVFLALGGVFLDAYDLTTLSYGIDDVVREFQLSPLLTGLVTSS
IMVGTIVGNIIGGWLTDKYGRYSVFMADMFFFVISAIAAGLAPNVWVLIGARFLMGIGVGIDLPVAMSYLAEFSRFAGKG
NKAARLAAWCPMWYAASTVCFLIIFGLYFLLPQEHLDWLWRASLLFGAVPALLIIAVRSRFMNESPLWAANQGDLTSAVR
ILRDSWGIHAHEVPAAKPAPAPKVSFRVLFEKPYRERTIVAGVMNICISFEYTAIAFFLPSILAQFLGAGVFETISASLG
LNALFAFTGGLLGMHLAWKYPSRHVAIAGFALQFVALIVLALVGQPHATAGIVLAIAMLGLWLFAEGFGPGAQLMIYPAL
SYPTAIRATGVGFSRALSGIGSALALFILPLLQAYLGTQMFWVVSLAAIIPIFFLLAVRHEPTREDIDALHE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786229, Length=403, Percent_Identity=28.0397022332506, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI87082159, Length=410, Percent_Identity=28.5365853658537, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1788068, Length=430, Percent_Identity=25.3488372093023, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788074, Length=384, Percent_Identity=25.78125, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789207, Length=253, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789312, Length=462, Percent_Identity=25.3246753246753, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87082404, Length=407, Percent_Identity=21.3759213759214, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 51044; Mature: 50913

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
>Mature Secondary Structure 
STLPVDNPGIASVPVSSVGDVARLINSGKEHAKYARMIVFLALGGVFLDAYDLTTLSYG
CCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1630901; 9278503 [H]