Click here to switch to the map view.

The map label for this gene is surE [H]

Identifier: 238896224

GI number: 238896224

Start: 4197536

End: 4198297

Strand: Reverse

Name: surE [H]

Synonym: KP1_4376

Alternate gene names: 238896224

Gene position: 4198297-4197536 (Counterclockwise)

Preceding gene: 238896225

Following gene: 238896223

Centisome position: 79.99

GC content: 61.68

Gene sequence:

>762_bases
ATGCGAATATTGCTGAGTAACGATGACGGGATCCATGCGCCGGGGATACAGACCCTGGCGAAGGCCTTAAGGGAGTTTGC
CGAGGTCCAGGTGGTTGCACCCGATCGTAACCGCAGCGGGGCCTCAAATTCGCTGACGCTGGAATCGTCCCTGCGTACGT
TTACCTTTGAAAATGGCGACATCGCCGTCCAGATGGGCACCCCGACCGACTGTGTCTATCTCGGCGTGAACGCGCTGATG
CGCCCGCGTCCGGACATCGTGGTTTCCGGCATTAATGCCGGCCCCAACCTGGGCGACGACGTCATCTATTCCGGCACCGT
GGCCGCGGCGATGGAAGGCCGTCATCTGGGGTTCCCCGCGCTGGCCGTGTCGCTGAACGGCTATCAGCATTACGATACCG
CCGCGGCGGTAACCTGCACCATTCTGCGCGCCTTAAGCCGCGAGCCGCTGCGTACCGGGCGGATCCTTAACATCAACGTG
CCGGATCTCCCGCTTGATCAAATCAAGGGCATTCGCGTGACCCGCTGCGGCAACCGCCATCCGGCCGACCAGGTGATCCC
GCAAAAAGATCCGCGCGGCAACACCCTGTACTGGATTGGCCCGCCGGGCGATAAGCGCGATGCCGGGCCGGGCACCGATT
TTGCGGCAGTGGATGAAGGCTATGTTTCCGTGACGCCATTGCACGTCGATTTAACCGCCCATCAGGCGCATGAGGTGGTC
ACCGATTGGCTGGAACGTGTCGGGGTTGACAGGCAATGGTAA

Upstream 100 bases:

>100_bases
AACTGGTGGGATGACGTAACCGTTGAACTACGTTTCTGGCTGCCGGCGGGCAGCTTCGCCACCAGCGTGGTCAGGGAGCT
TATCAATACAACGGGTGACT

Downstream 100 bases:

>100_bases
GTAAACGTGTTGAAAGTTTGTTGAATCAACTGCGCACGCAGGGCATCGTCGATGAACGTGTCCTCGAGGCGATCGCGCTG
GTCCCGCGCGAAAAGTTTGT

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: 5'/3'-nucleotidase; Nucleoside monophosphate phosphohydrolase; Exopolyphosphatase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MRILLSNDDGIHAPGIQTLAKALREFAEVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALM
RPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCTILRALSREPLRTGRILNINV
PDLPLDQIKGIRVTRCGNRHPADQVIPQKDPRGNTLYWIGPPGDKRDAGPGTDFAAVDEGYVSVTPLHVDLTAHQAHEVV
TDWLERVGVDRQW

Sequences:

>Translated_253_residues
MRILLSNDDGIHAPGIQTLAKALREFAEVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALM
RPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCTILRALSREPLRTGRILNINV
PDLPLDQIKGIRVTRCGNRHPADQVIPQKDPRGNTLYWIGPPGDKRDAGPGTDFAAVDEGYVSVTPLHVDLTAHQAHEVV
TDWLERVGVDRQW
>Mature_253_residues
MRILLSNDDGIHAPGIQTLAKALREFAEVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALM
RPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCTILRALSREPLRTGRILNINV
PDLPLDQIKGIRVTRCGNRHPADQVIPQKDPRGNTLYWIGPPGDKRDAGPGTDFAAVDEGYVSVTPLHVDLTAHQAHEVV
TDWLERVGVDRQW

Specific function: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'- monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase acti

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family [H]

Homologues:

Organism=Escherichia coli, GI1789101, Length=253, Percent_Identity=91.699604743083, Blast_Score=479, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002828 [H]

Pfam domain/function: PF01975 SurE [H]

EC number: =3.1.3.5; =3.1.3.6; =3.6.1.11 [H]

Molecular weight: Translated: 27365; Mature: 27365

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLSNDDGIHAPGIQTLAKALREFAEVQVVAPDRNRSGASNSLTLESSLRTFTFENGD
CEEEEECCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCEEEEECCCEEEEEECCC
IAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPA
EEEEECCCCCEEEECHHHHCCCCCCEEEECCCCCCCCCCCEEECCEEEEEECCCCCCCCE
LAVSLNGYQHYDTAAAVTCTILRALSREPLRTGRILNINVPDLPLDQIKGIRVTRCGNRH
EEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHCCEEEEECCCCC
PADQVIPQKDPRGNTLYWIGPPGDKRDAGPGTDFAAVDEGYVSVTPLHVDLTAHQAHEVV
CHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCEEEEEEEEEEECHHHHHHHH
TDWLERVGVDRQW
HHHHHHHCCCCCC
>Mature Secondary Structure
MRILLSNDDGIHAPGIQTLAKALREFAEVQVVAPDRNRSGASNSLTLESSLRTFTFENGD
CEEEEECCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCEEEEECCCEEEEEECCC
IAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPA
EEEEECCCCCEEEECHHHHCCCCCCEEEECCCCCCCCCCCEEECCEEEEEECCCCCCCCE
LAVSLNGYQHYDTAAAVTCTILRALSREPLRTGRILNINVPDLPLDQIKGIRVTRCGNRH
EEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHCCEEEEECCCCC
PADQVIPQKDPRGNTLYWIGPPGDKRDAGPGTDFAAVDEGYVSVTPLHVDLTAHQAHEVV
CHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCEEEEEEEEEEECHHHHHHHH
TDWLERVGVDRQW
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA