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The map label for this gene is sitC [H]

Identifier: 238896200

GI number: 238896200

Start: 4173177

End: 4174025

Strand: Direct

Name: sitC [H]

Synonym: KP1_4349

Alternate gene names: 238896200

Gene position: 4173177-4174025 (Clockwise)

Preceding gene: 238896199

Following gene: 238896201

Centisome position: 79.51

GC content: 60.78

Gene sequence:

>849_bases
ATGAGCTGGCTGCTGGAGCCGTTTGGCTATCACTATATGCTCAATGCGATGTGGGTGTCGGCGCTGGTGGGCGGCGTCTG
TGCGTTTCTCTCCTGCTACCTGATGCTCAAAGGCTGGTCGCTGATTGGCGACGCCCTCTCCCACTCGATTGTACCCGGCG
TCGCCGGGGCCTATATGCTCGGCCTGCCTTTCGCGCTCGGCGCATTTCTCTCCGGCGGTCTGGCGGCGGGCAGCATGCTG
TTTTTGCAACAGCGCTCGCGGCTAAAAGAGGATGCCATTATCGGGCTGATCTTCTCCTCCTTCTTCGGGATCGGGCTGTT
TATGGTGTCGCTGAATCCGACGTCGGTGAATATTCAGACCATTATCCTCGGCAATATTCTGGCCATCGCCCCGGAGGATA
TTATCCAGCTGGCGGCGATCGGCTTTATCTCAATGGCGATTCTGCTGCTGAAATGGAAAGACCTGATGGTGACCTTCTTT
GATGAACACCATGCCCGCTCGATTGGCCTGAACACCCGCGGCCTGAAGCTGCTGTTCTTTACCCTGCTGGCCGCCTGCAC
CGTGGCGGCGCTGCAGACCGTCGGCGCCTTTCTGGTCATCTGCCTGGTGGTCACTCCCGGGGCTACCGCGTGGCTGTTAA
CCGATCGCTTCCCGCGCCTGCTGGCTATCGCCGTGTCTATCGGCAGCCTGACCAGTTTCTTCGGCGCCTGGCTCAGCTAC
TATCTCGACGGCGCCACCGGCGGCATTATCGTGGTCGCGCAAACGCTGCTGTTCCTCATCACCTTTATCTTCGCGCCGAA
GCACGGCCTGCTGGCCAGCCGCCGCCGCGCCAGGGAGGCCGCATGCTGA

Upstream 100 bases:

>100_bases
GCGGCGTGCTGCGCCACGTCGCGCTCACCGGCGGGGAAGCGCAGGTTATCACCGATGACGAGCGGCCGTTTATCAGCCGG
CGCGCGGCGGGAGGCCCACG

Downstream 100 bases:

>100_bases
ACCTGTTCCTGGCCCCGTTCCAGTTTCCTTTTATGGTCAATGCGATAGCGATATCGATCGTCGTCGCCATTCCCTGCGCG
CTGCTGTCGGTGTTTCTGGT

Product: iron transport system inner membrane permease component

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSWLLEPFGYHYMLNAMWVSALVGGVCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAYMLGLPFALGAFLSGGLAAGSML
FLQQRSRLKEDAIIGLIFSSFFGIGLFMVSLNPTSVNIQTIILGNILAIAPEDIIQLAAIGFISMAILLLKWKDLMVTFF
DEHHARSIGLNTRGLKLLFFTLLAACTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLAIAVSIGSLTSFFGAWLSY
YLDGATGGIIVVAQTLLFLITFIFAPKHGLLASRRRAREAAC

Sequences:

>Translated_282_residues
MSWLLEPFGYHYMLNAMWVSALVGGVCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAYMLGLPFALGAFLSGGLAAGSML
FLQQRSRLKEDAIIGLIFSSFFGIGLFMVSLNPTSVNIQTIILGNILAIAPEDIIQLAAIGFISMAILLLKWKDLMVTFF
DEHHARSIGLNTRGLKLLFFTLLAACTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLAIAVSIGSLTSFFGAWLSY
YLDGATGGIIVVAQTLLFLITFIFAPKHGLLASRRRAREAAC
>Mature_281_residues
SWLLEPFGYHYMLNAMWVSALVGGVCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAYMLGLPFALGAFLSGGLAAGSMLF
LQQRSRLKEDAIIGLIFSSFFGIGLFMVSLNPTSVNIQTIILGNILAIAPEDIIQLAAIGFISMAILLLKWKDLMVTFFD
EHHARSIGLNTRGLKLLFFTLLAACTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLAIAVSIGSLTSFFGAWLSYY
LDGATGGIIVVAQTLLFLITFIFAPKHGLLASRRRAREAAC

Specific function: Part of an ATP-driven transport system yfeABC for chelated iron [H]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=240, Percent_Identity=28.75, Blast_Score=85, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 30334; Mature: 30202

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWLLEPFGYHYMLNAMWVSALVGGVCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAYML
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
GLPFALGAFLSGGLAAGSMLFLQQRSRLKEDAIIGLIFSSFFGIGLFMVSLNPTSVNIQT
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEE
IILGNILAIAPEDIIQLAAIGFISMAILLLKWKDLMVTFFDEHHARSIGLNTRGLKLLFF
EEEHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
TLLAACTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLAIAVSIGSLTSFFGAWLSY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLDGATGGIIVVAQTLLFLITFIFAPKHGLLASRRRAREAAC
HHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SWLLEPFGYHYMLNAMWVSALVGGVCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAYML
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
GLPFALGAFLSGGLAAGSMLFLQQRSRLKEDAIIGLIFSSFFGIGLFMVSLNPTSVNIQT
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEE
IILGNILAIAPEDIIQLAAIGFISMAILLLKWKDLMVTFFDEHHARSIGLNTRGLKLLFF
EEEHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
TLLAACTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLAIAVSIGSLTSFFGAWLSY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLDGATGGIIVVAQTLLFLITFIFAPKHGLLASRRRAREAAC
HHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9495751; 11586360; 12142430 [H]